Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway

The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure

(2015) Na Xu et al.   JOURNAL OF PATHOLOGY

Inhibition of prenyltransferase activity by statins in both liver and muscle cell lines is not causative of cytotoxicity

(2015) Rowena H. Gee et al.   TOXICOLOGY

Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection

(2013) Xiu-Xing Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Glucose Transport by ROCK1 Differs from That of ROCK2 and Is Controlled by Actin Polymerization

(2012) Kwang-Hoon Chun et al.   ENDOCRINOLOGY

Cigarette Smoke–Induced Pulmonary Inflammatory Responses Are Mediated by EGR-1/GGPPS/MAPK Signaling

(2011) Ning Shen et al.   AMERICAN JOURNAL OF PATHOLOGY

Geranylgeranyl pyrophosphate stimulates PPARγ expression and adipogenesis through the inhibition of osteoblast differentiation

(2011) Megan M. Weivoda et al.   BONE

Mice with AS160/TBC1D4-Thr649Ala Knockin Mutation Are Glucose Intolerant with Reduced Insulin Sensitivity and Altered GLUT4 Trafficking

(2011) Shuai Chen et al.   Cell Metabolism

Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice

(2011) Xiao Yu et al.   EMBO JOURNAL

An Early Response Transcription Factor, Egr-1, Enhances Insulin Resistance in Type 2 Diabetes with Chronic Hyperinsulinism

(2011) Ning Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials

(2010) Naveed Sattar et al.   LANCET

Targeted Disruption of ROCK1 Causes Insulin Resistancein Vivo

(2009) Dae Ho Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms involved in cholesterol-induced neuronal insulin resistance

(2009) Changiz Taghibiglou et al.   NEUROPHARMACOLOGY

Palmitate acutely induces insulin resistance in isolated muscle from obese but not lean humans

(2008) A. Brianne Thrush et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Free fatty acids and skeletal muscle insulin resistance

(2008) Edward W Kraegen et al.   CURRENT OPINION IN LIPIDOLOGY

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Statin modulates insulin signaling and insulin resistance in liver and muscle of rats fed a high-fat diet

(2007) Cristina Alba Lalli et al.   METABOLISM-CLINICAL AND EXPERIMENTAL