Clemastine improves hypomyelination in rats with hypoxic–ischemic brain injury by reducing microglia-derived IL-1β via P38 signaling pathway

Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells

(2019) Souvarish Sarkar et al.   Science Signaling

Anti-Inflammatory Effect of Sulforaphane on LPS-Activated Microglia Potentially through JNK/AP-1/NF-κB Inhibition and Nrf2/HO-1 Activation

(2019) Lalita Subedi et al.   Cells

The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins

(2019) Vandana Deora et al.   GLIA

HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway

(2018) Shalini Swaroop et al.   Journal of Neuroinflammation

Neutralization of Interleukin-1β following Diffuse Traumatic Brain Injury in the Mouse attenuates the loss of Mature Oligodendrocytes

(2018) Johanna Flygt et al.   JOURNAL OF NEUROTRAUMA

White matter is what matters after cardiac arrest

(2018) Tobias Cronberg   LANCET NEUROLOGY

Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination

(2018) Sara Calabretta et al.   DEVELOPMENTAL CELL

Inhibitors of NF-κB and P2X7/NLRP3/Caspase 1 pathway in microglia: Novel therapeutic opportunities in neuroinflammation induced early-stage Alzheimer’s disease

(2018) Baban S. Thawkar et al.   JOURNAL OF NEUROIMMUNOLOGY

Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus

(2018) Wen-Jun Su et al.   Frontiers in Cellular Neuroscience

Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury

(2017) Lawrence R. Shiow et al.   GLIA

Activation of the NLRP3 inflammasome in microglia: the role of ceramide

(2017) Hannah Scheiblich et al.   JOURNAL OF NEUROCHEMISTRY

Microglia-derived IL-1β contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats

(2017) Qianpeng Han et al.   Journal of Neuroinflammation

Clemastine fumarate for promotion of optic nerve remyelination

(2017) Jeffrey A Cohen et al.   LANCET

The association between anemia and neurological outcome in hypoxic ischemic brain injury after cardiac arrest

(2017) Andrew Wormsbecker et al.   RESUSCITATION

The role of the NG2 proteoglycan in OPC and CNS network function

(2016) Dominik Sakry et al.   BRAIN RESEARCH

Administration of vitamin D 3 induces CNPase and myelin oligodendrocyte glycoprotein expression in the cerebral cortex of the murine model of cuprizone-induced demyelination

(2016) Farhad Mashayekhi et al.   FOLIA NEUROPATHOLOGICA

Effect of Inhaled Xenon on Cerebral White Matter Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest

(2016) Ruut Laitio et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation

(2016) Sandra M. Rocha et al.   Journal of Neuroinflammation

Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice

(2016) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Electromagnetic pulse activated brain microglia via the p38 MAPK pathway

(2016) Long-Long Yang et al.   NEUROTOXICOLOGY

The effect of triiodothyronine on maturation and differentiation of oligodendrocyte progenitor cells during remyelination following induced demyelination in male albino rat

(2016) H. El-Tahry et al.   TISSUE & CELL

Prophylactic Chronic Zinc Administration Increases Neuroinflammation in a Hypoxia-Ischemia Model

(2016) Constantino Tomas-Sanchez et al.   Journal of Immunology Research

IL-1β induces hypomyelination in the periventricular white matter through inhibition of oligodendrocyte progenitor cell maturation via FYN/MEK/ERK signaling pathway in septic neonatal rats

(2015) Di Xie et al.   GLIA

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Neuroinflammation: Targeting neuroinflammation through inhibition of NLRP3

(2015) Alex Chase   Nature Reviews Neurology

Rosiglitazone Promotes White Matter Integrity and Long-Term Functional Recovery After Focal Cerebral Ischemia

(2015) Lijuan Han et al.   STROKE

TAPP1 inhibits the differentiation of oligodendrocyte precursor cells via suppressing the Mek/Erk pathway

(2015) Yidan Chen et al.   Neuroscience Bulletin

Clemastine rescues behavioral changes and enhances remyelination in the cuprizone mouse model of demyelination

(2015) Zhifang Li et al.   Neuroscience Bulletin

IL-17A activates ERK1/2 and enhances differentiation of oligodendrocyte progenitor cells

(2014) Jane M. Rodgers et al.   GLIA

Interaction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation

(2014) JinXiang Dai et al.   GLIA

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Clemastine Confers Neuroprotection and Induces an Anti-Inflammatory Phenotype in SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

(2014) Savina Apolloni et al.   MOLECULAR NEUROBIOLOGY

Ischemia-Induced Neuroinflammation Is Associated with Disrupted Development of Oligodendrocyte Progenitors in a Model of Periventricular Leukomalacia

(2013) Sina Falahati et al.   DEVELOPMENTAL NEUROSCIENCE

Oligodendrocyte differentiation and signaling after transferrin internalization: A mechanism of action

(2013) María Julia Pérez et al.   EXPERIMENTAL NEUROLOGY

Microglial activation of the NLRP3 inflammasome by the priming signals derived from macrophages infected with mycobacteria

(2012) Hye-Mi Lee et al.   GLIA

Oligodendrocyte degeneration and recovery after focal cerebral ischemia

(2010) S.R. McIver et al.   NEUROSCIENCE