HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway

The p38 Mitogen-Activated Protein Kinase Critically Regulates Human Keratinocyte Inflammasome Activation

(2018) Gabriele Fenini et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection

(2017) Bibhabasu Hazra et al.   Science Signaling

The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection

(2017) Bibhabasu Hazra et al.   Science Signaling

Inflammasome Complexes: Emerging Mechanisms and Effector Functions

(2016) Vijay A.K. Rathinam et al.   CELL

Tyrosine phosphorylation modulates mitochondrial chaperonin Hsp60 and delays rotavirus NSP4-mediated apoptotic signaling in host cells

(2016) Shiladitya Chattopadhyay et al.   CELLULAR MICROBIOLOGY

HSP60 plays a regulatory role in IL-1β-induced microglial inflammation via TLR4-p38 MAPK axis

(2016) Shalini Swaroop et al.   Journal of Neuroinflammation

Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus?

(2016) Joshua Juwono et al.   Journal of Diabetes Research

Antisense oligonucleotides in therapy for neurodegenerative disorders

(2015) Melvin M. Evers et al.   ADVANCED DRUG DELIVERY REVIEWS

Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage

(2015) Denise N. Bronner et al.   IMMUNITY

Interleukin-1 and acute brain injury

(2015) Katie N. Murray et al.   Frontiers in Cellular Neuroscience

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease

(2014) Carmen Noelker et al.   Journal of Neuroinflammation

MicroRNA 155 Regulates Japanese Encephalitis Virus-Induced Inflammatory Response by Targeting Src Homology 2-Containing Inositol Phosphatase 1

(2014) M. C. Thounaojam et al.   JOURNAL OF VIROLOGY

Aberrant Expression of Interleukin-1β and Inflammasome Activation in Human Malignant Gliomas

(2014) Leonid Tarassishin et al.   PLoS One

Virus Infections in the Nervous System

(2013) Orkide O. Koyuncu et al.   Cell Host & Microbe

Interleukin-1β orchestrates underlying inflammatory responses in microglia via Krüppel-like factor 4

(2013) Deepak K. Kaushik et al.   JOURNAL OF NEUROCHEMISTRY

Activation of microglia induces symptoms of Parkinson’s disease in wild-type, but not in IL-1 knockout mice

(2013) Sachiko Tanaka et al.   Journal of Neuroinflammation

Rabies Virus Is Recognized by the NLRP3 Inflammasome and Activates Interleukin-1  Release in Murine Dendritic Cells

(2013) T. M. Lawrence et al.   JOURNAL OF VIROLOGY

Neuroinflammatory basis of metabolic syndrome

(2013) Sudarshana Purkayastha et al.   Molecular Metabolism

A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s disease

(2012) Branden Stansley et al.   Journal of Neuroinflammation

NLRP3 Inflammasome: Key Mediator of Neuroinflammation in Murine Japanese Encephalitis

(2012) Deepak Kumar Kaushik et al.   PLoS One

Heat Shock Protein 60 and Immune Inflammatory Responses in Atherosclerosis

(2011) Cecilia Grundtman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interleukin-1 and Stroke: Biomarker, Harbinger of Damage, and Therapeutic Target

(2011) Adam Denes et al.   CEREBROVASCULAR DISEASES

Role of microglia in CNS inflammation

(2011) Manuel B. Graeber et al.   FEBS LETTERS

Use of vivo-morpholinos for control of protein expression in the adult rat brain

(2011) Kathryn J. Reissner et al.   JOURNAL OF NEUROSCIENCE METHODS

Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease

(2010) F. Meissner et al.   BLOOD

Vivo-Morpholino knockdown of αIIb: A novel approach to inhibit thrombocyte function in adult zebrafish

(2010) Seongcheol Kim et al.   BLOOD CELLS MOLECULES AND DISEASES

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

The HSP60 immune system network

(2010) Francisco J. Quintana et al.   TRENDS IN IMMUNOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Octa-guanidine Morpholino Restores Dystrophin Expression in Cardiac and Skeletal Muscles and Ameliorates Pathology in Dystrophic mdx Mice

(2009) Bo Wu et al.   MOLECULAR THERAPY

Japanese Encephalitis—A Pathological and Clinical Perspective

(2009) Debapriya Ghosh et al.   PLoS Neglected Tropical Diseases

Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease

(2008) M. C. Pott Godoy et al.   BRAIN

Minocycline neuroprotects, reduces microglial activation, inhibits caspase 3 induction, and viral replication following Japanese encephalitis

(2008) Manoj Kumar Mishra et al.   JOURNAL OF NEUROCHEMISTRY

Japanese Encephalitis Virus infection induces IL-18 and IL-1β in microglia and astrocytes: Correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death

(2008) Sulagna Das et al.   JOURNAL OF NEUROIMMUNOLOGY

A Vicious Cycle Involving Release of Heat Shock Protein 60 from Injured Cells and Activation of Toll-Like Receptor 4 Mediates Neurodegeneration in the CNS

(2008) S. Lehnardt et al.   JOURNAL OF NEUROSCIENCE

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Interleukin-1β and interleukin-6 disturb the antioxidant enzyme system in bovine chondrocytes: a possible explanation for oxidative stress generation

(2008) M. Mathy-Hartert et al.   OSTEOARTHRITIS AND CARTILAGE