Immune and Inflammatory Determinants Underlying Alzheimer’s Disease Pathology

Biotin Deficiency Induces Th1- and Th17-Mediated Proinflammatory Responses in Human CD4+T Lymphocytes via Activation of the mTOR Signaling Pathway

(2018) Asif Elahi et al.   JOURNAL OF IMMUNOLOGY

Peripheral imbalanced TFH/TFR ratio correlates with intrathecal IgG synthesis in multiple sclerosis at clinical onset

(2018) Marco Puthenparampil et al.   Multiple Sclerosis Journal

Peripheral imbalanced TFH/TFR ratio correlates with intrathecal IgG synthesis in multiple sclerosis at clinical onset

(2018) Marco Puthenparampil et al.   Multiple Sclerosis Journal

IgM response against amyloid-beta in aging: a potential peripheral protective mechanism

(2018) Sudhanshu Agrawal et al.   Alzheimers Research & Therapy

Peripheral immune system in aging and Alzheimer’s disease

(2018) Wei Cao et al.   Molecular Neurodegeneration

T follicular helper (Tfh) cells in lupus: Activation and involvement in SLE pathogenesis

(2016) Patrick Blanco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Elimination of microglia improves cognitive function following cranial irradiation

(2016) Munjal M. Acharya et al.   Scientific Reports

Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses

(2016) Jialong Yang et al.   eLife

Advances in IL-21 biology—enhancing our understanding of human disease

(2015) Stuart G Tangye   CURRENT OPINION IN IMMUNOLOGY

Association of circulating follicular helper T cells with disease course of NMO spectrum disorders

(2015) Yu-Jing Li et al.   JOURNAL OF NEUROIMMUNOLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Pathophysiology of T follicular helper cells in humans and mice

(2015) Hideki Ueno et al.   NATURE IMMUNOLOGY

Innate immunity in Alzheimer's disease

(2015) Michael T Heneka et al.   NATURE IMMUNOLOGY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Circulating CCR7+ICOS+ Memory T Follicular Helper Cells in Patients with Multiple Sclerosis

(2015) Xueli Fan et al.   PLoS One

Intravenous Immunoglobulins for Alzheimer’s Disease

(2014) Lakshman Puli et al.   Current Alzheimer Research

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

(2014) Shane Crotty   IMMUNITY

T cell–derived interleukin (IL)-21 promotes brain injury following stroke in mice

(2014) Benjamin D.S. Clarkson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Beta-amyloid auto-antibodies are reduced in Alzheimer's disease

(2014) Bao-Xi Qu et al.   JOURNAL OF NEUROIMMUNOLOGY

Interleukin-21: a double-edged sword with therapeutic potential

(2014) Rosanne Spolski et al.   NATURE REVIEWS DRUG DISCOVERY

Human B-1 cells take the stage

(2013) Thomas L. Rothstein et al.   Annals of the New York Academy of Sciences

Th17 Cell-Mediated Neuroinflammation Is Involved in Neurodegeneration of Aβ1-42-Induced Alzheimer’s Disease Model Rats

(2013) Jun Zhang et al.   PLoS One

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

B-1 B Cell Development in the Fetus and Adult

(2012) Encarnacion Montecino-Rodriguez et al.   IMMUNITY

Type17 T-cells in Central Nervous System Autoimmunity and Tumors

(2012) Hideho Okada et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Protective Roles of Natural IgM Antibodies

(2012) Caroline Grönwall et al.   Frontiers in Immunology

IL-21 is the primary common   chain-binding cytokine required for human B-cell differentiation in vivo

(2011) M. Recher et al.   BLOOD

Targeting Interleukin-21 in Immune-Mediated Pathologies

(2010) Massimiliano Sarra et al.   CURRENT DRUG TARGETS

IgM Antibodies to Apoptosis-Associated Determinants Recruit C1q and Enhance Dendritic Cell Phagocytosis of Apoptotic Cells

(2009) Yifang Chen et al.   JOURNAL OF IMMUNOLOGY

T Follicular Helper (TFH) Cells in Normal and Dysregulated Immune Responses

(2008) Cecile King et al.   Annual Review of Immunology