IL-21 is the primary common   chain-binding cytokine required for human B-cell differentiation in vivo

STAT3-Mediated Up-Regulation of BLIMP1 Is Coordinated with BCL6 Down-Regulation to Control Human Plasma Cell Differentiation

(2014) S. A. Diehl et al.   JOURNAL OF IMMUNOLOGY

IL-21-Induced Isotype Switching to IgG and IgA by Human Naive B Cells Is Differentially Regulated by IL-4

(2014) D. T. Avery et al.   JOURNAL OF IMMUNOLOGY

Regulation of T follicular helper cell formation and function by antigen presenting cells

(2010) Elissa K Deenick et al.   CURRENT OPINION IN IMMUNOLOGY

Transplantation of hematopoietic stem cells in human severe combined immunodeficiency: longterm outcomes

(2010) Rebecca H. Buckley   IMMUNOLOGIC RESEARCH

B-cell function in severe combined immunodeficiency after stem cell or gene therapy: A review

(2010) Rebecca H. Buckley   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

B cell–intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

(2010) Danielle T. Avery et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

(2010) Michelle A. Linterman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism

(2010) Dimitra Zotos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An optimized assay for the enumeration of antigen-specific memory B cells in different compartments of the human body

(2010) Yanran Cao et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency

(2010) Capucine Picard et al.   MEDICINE

Control systems and decision making for antibody production

(2010) Christopher C Goodnow et al.   NATURE IMMUNOLOGY

Interleukin-15 expression affects homeostasis and function of B cells through NK cell-derived interferon-γ

(2009) Navkiran Gill et al.   CELLULAR IMMUNOLOGY

Memory B cells: Effectors of long-lived immune responses

(2009) Stuart G. Tangye et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12

(2009) Cindy S Ma et al.   IMMUNOLOGY AND CELL BIOLOGY

Outcomes of patients with severe combined immunodeficiency treated with hematopoietic stem cell transplantation with and without preconditioning

(2009) Niraj C. Patel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Long-term Clinical Outcome of Patients with Severe Combined Immunodeficiency Who Received Related Donor Bone Marrow Transplants without Pretransplant Chemotherapy or Post-transplant GVHD Prophylaxis

(2009) Mary Dell Railey et al.   JOURNAL OF PEDIATRICS

STAT3 is required for IL-21-induced secretion of IgE from human naive B cells

(2008) D. T. Avery et al.   BLOOD

Clinical and immunologic consequences of a somatic reversion in a patient with X-linked severe combined immunodeficiency

(2008) C. Speckmann et al.   BLOOD

The role of IL-21 in regulating B-cell function in health and disease

(2008) Rachel Ettinger et al.   IMMUNOLOGICAL REVIEWS