Human B-1 cells take the stage

Human antibodies reactive to NeuGcGM3 ganglioside have cytotoxic antitumor properties

(2013) Nely Rodríguez-Zhurbenko et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Immunophenotyping of putative human B1 B cells in healthy controls and common variable immunodeficiency (CVID) patients

(2012) O. Suchanek et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human CD20+CD43+CD27+CD5− B cells generate antibodies to capsular polysaccharides of Streptococcus pneumoniae

(2012) Bert Verbinnen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Human CD11b+B1 cells are not monocytes: A reply to “Gene profiling of CD11b+and CD11b−B1 cell subsets reveals potential cell sorting artifacts”: Figure 1.

(2012) Daniel O. Griffin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gene profiling of CD11b+and CD11b−B1 cell subsets reveals potential cell sorting artifacts: Figure 1.

(2012) Claude-Agnès Reynaud et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Unknown

(2012) Daniel Griffin et al.   MOLECULAR MEDICINE

Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling

(2012) Marcus Dühren-von Minden et al.   NATURE

Expression of plasma cell alloantigen 1 defines layered development of B-1a B-cell subsets with distinct innate-like functions

(2012) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct B-cell lineage commitment distinguishes adult bone marrow hematopoietic stem cells

(2012) E. E. B. Ghosn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antigen-specific memory in B-1a and its relationship to natural immunity

(2012) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antigen-specific antibody responses in B-1a and their relationship to natural immunity

(2012) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

(2012) Joan Yuan et al.   SCIENCE

Induction of Th17 cell differentiation by B-1 cells

(2012) Yi Wang et al.   Frontiers in Immunology

Human B1 Cell Frequency: Isolation and Analysis of Human B1 Cells

(2012) Daniel O. Griffin et al.   Frontiers in Immunology

B1a B Lymphocytes Are Atheroprotective by Secreting Natural IgM That Increases IgM Deposits and Reduces Necrotic Cores in Atherosclerotic Lesions

(2011) Tin Kyaw et al.   CIRCULATION RESEARCH

B-1 cells in the bone marrow are a significant source of natural IgM

(2011) Youn Soo Choi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A small CD11b+human B1 cell subpopulation stimulates T cells and is expanded in lupus

(2011) Daniel O. Griffin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human B1 cells are CD3−: A reply to “A human equivalent of mouse B-1 cells?” and “The nature of circulating CD27+CD43+B cells”: Figure 1.

(2011) Daniel O. Griffin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A human equivalent of mouse B-1 cells?: Figure 1.

(2011) Marc Descatoire et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The nature of circulating CD27+CD43+B cells: Figure 1.

(2011) Martin Perez-Andres et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70−

(2011) Daniel O. Griffin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulatory T Cells from IL-10-Deficient Mice Fail to Suppress Contact Hypersensitivity Reactions Due to Lack of Adenosine Production

(2011) Sabine Ring et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Pivotal Advance: Peritoneal cavity B-1 B cells have phagocytic and microbicidal capacities and present phagocytosed antigen to CD4+ T cells

(2011) D. Parra et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Distinct progenitors for B-1 and B-2 cells are present in adult mouse spleen

(2011) E. E. B. Ghosn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential

(2011) M. Yoshimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characteristics of Borrelia hermsii infection in human hematopoietic stem cell-engrafted mice mirror those of human relapsing fever

(2011) R. Vuyyuru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced production of B-1-specified common lymphoid progenitors results in diminished potential of adult marrow to generate B-1 cells

(2011) C. L. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A CD25− Positive Population of Activated B1 Cells Expresses LIFR and Responds to LIF

(2011) Joseph R. Tumang et al.   Frontiers in Immunology

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

IL-10 produced by activated human B cells regulates CD4+ T-cell activation in vitro

(2010) Jean-David Bouaziz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunoglobulin secretion by B1 cells: Differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells

(2010) Nichol E. Holodick et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

(2010) Hugo Mouquet et al.   NATURE

A retrospective seven-year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at university college london hospital: The first fifty patients

(2009) Tim Y.-T. Lu et al.   ARTHRITIS AND RHEUMATISM

A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice

(2009) Xuemei Zhong et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase ii/iii systemic lupus erythematosus evaluation of rituximab trial

(2009) Joan T. Merrill et al.   ARTHRITIS AND RHEUMATISM

Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells

(2009) S. Duber et al.   BLOOD

B cell depletion in lupus and Sjögrenʼs syndrome: an update

(2009) Andreea Coca et al.   CURRENT OPINION IN RHEUMATOLOGY

Adult BM generates CD5+ B1 cells containing abundant N-region additions

(2009) Nichol E. Holodick et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulation of Dendritic Cells and Macrophages by an Anti-Apoptotic Cell Natural Antibody that Suppresses TLR Responses and Inhibits Inflammatory Arthritis

(2009) Y. Chen et al.   JOURNAL OF IMMUNOLOGY

Identification and Characterization of a Human CD5+ Pre-Naive B Cell Population

(2009) J. Lee et al.   JOURNAL OF IMMUNOLOGY

Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells

(2009) Nichol E. Holodick et al.   MOLECULAR IMMUNOLOGY

CD19 signaling is impaired in murine peritoneal and splenic B-1 B lymphocytes

(2009) Trivikram Dasu et al.   MOLECULAR IMMUNOLOGY

Phenotypic Characterization of Autoreactive B Cells—Checkpoints of B Cell Tolerance in Patients with Systemic Lupus Erythematosus

(2009) Annett M. Jacobi et al.   PLoS One

A differentiation pathway for B1 cells in adult bone marrow

(2009) B. L. Esplin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease

(2009) M. Britschgi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural human antibodies to amyloid beta peptide

(2008) Paul Szabo et al.   AUTOIMMUNITY REVIEWS

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

(2008) Koichi Yanaba et al.   IMMUNITY

Regulatory B cells as inhibitors of immune responses and inflammation

(2008) Jean-David Bouaziz et al.   IMMUNOLOGICAL REVIEWS

T cell–independent development and induction of somatic hypermutation in human IgM+IgD+CD27+B cells

(2008) Ferenc A. Scheeren et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

(2007) Thomas Tiller et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Autoantibodies in lung cancer: possibilities for early detection and subsequent cure

(2007) C J Chapman et al.   THORAX