Endoplasmic Reticulum Stress Pathway, the Unfolded Protein Response, Modulates Immune Function in the Tumor Microenvironment to Impact Tumor Progression and Therapeutic Response

Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β–induced Serpine1

(2019) James V. McCann et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting the Tumor Microenvironment in Radiation Oncology: Proceedings from the 2018 ASTRO–AACR Research Workshop

(2019) Heather M. McGee et al.   CLINICAL CANCER RESEARCH

Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy

(2019) Tongyan Liu et al.   Journal of Hematology & Oncology

Knockdown of CEMIP suppresses proliferation and induces apoptosis in colorectal cancer cells: downregulation of GRP78 and attenuation of unfolded protein response

(2018) Guodong Liang et al.   Biochemistry and Cell Biology

Hexose-6-phosphate dehydrogenase controls cancer cell proliferation and migration through pleiotropic effects on the unfolded-protein response, calcium homeostasis, and redox balance

(2018) Maria Tsachaki et al.   FASEB JOURNAL

Endoplasmic reticulum chaperone GRP78 regulates macrophage function and insulin resistance in diet-induced obesity

(2018) Jong Hun Kim et al.   FASEB JOURNAL

T cell exhaustion in cancer: Mechanisms and clinical implications

(2018) Jin-Cheng Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oxidative stress drives CD8 + T-cell skin trafficking in patients with vitiligo through CXCL16 upregulation by activating the unfolded protein response in keratinocytes

(2017) Shuli Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Anastasis and the ER stress response: Solving the paradox of the unfolded protein response in cancer

(2017) Rafael Vincent M. Manalo   MEDICAL HYPOTHESES

Targeting the unfolded protein response in cancer

(2017) Rani Ojha et al.   PHARMACOLOGICAL RESEARCH

Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells

(2017) Jeffrey J. Rodvold et al.   Science Signaling

Novel prosurvival function of Yip1A in human cervical cancer cells: constitutive activation of the IRE1 and PERK pathways of the unfolded protein response

(2017) Yuki Taguchi et al.   Cell Death & Disease

Aurora kinase A inhibitor TCS7010 demonstrates pro‑apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells

(2017) Da Lee et al.   Oncology Letters

Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness

(2017) David R. Soto-Pantoja et al.   Oncotarget

Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP

(2017) Avital Lev et al.   Oncotarget

The microbiome and the hallmarks of cancer

(2017) Laura E. Fulbright et al.   PLoS Pathogens

Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells

(2017) Jeffrey J. Rodvold et al.   Science Signaling

Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate

(2017) Marco Corazzari et al.   Frontiers in Oncology

Silver nanoparticles induce irremediable endoplasmic reticulum stress leading to unfolded protein response dependent apoptosis in breast cancer cells

(2016) Jean-Christophe Simard et al.   APOPTOSIS

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Inflammatory immune infiltration in human tumors: Role in pathogenesis and prognostic and diagnostic value

(2016) A. V. Bogolyubova et al.   BIOCHEMISTRY-MOSCOW

Unfolded Protein Response Promotes Doxorubicin-Induced Nonsmall Cell Lung Cancer Cells Apoptosis via the mTOR Pathway Inhibition

(2016) Xiaofang Zhao et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Immune modulation by ER stress and inflammation in the tumor microenvironment

(2016) Jeffrey J. Rodvold et al.   CANCER LETTERS

A synthetic chalcone, 2'-hydroxy-2,3,5'-trimethoxychalcone triggers unfolded protein response-mediated apoptosis in breast cancer cells

(2016) Da Hyun Lee et al.   CANCER LETTERS

Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer

(2016) Katherine L. Cook et al.   CANCER RESEARCH

Reversing T-cell Dysfunction and Exhaustion in Cancer

(2016) H. M. Zarour   CLINICAL CANCER RESEARCH

Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses

(2016) Lauren N. Guthrie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis

(2016) Ehab A Ayaub et al.   JOURNAL OF PATHOLOGY

Estrogen signaling and unfolded protein response in breast cancer

(2016) Gayani Rajapaksa et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model

(2016) Leena Hilakivi-Clarke et al.   JNCI-Journal of the National Cancer Institute

Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors

(2016) Lei Zhang et al.   Molecular Oncology

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

(2016) Se Jin Im et al.   NATURE

How Cancers Escape Immune Destruction and Mechanisms of Action for the New Significantly Active Immune Therapies: Helping Nonimmunologists Decipher Recent Advances

(2016) J. L. Messerschmidt et al.   ONCOLOGIST

Muscadine Grape Skin Extract Induces an Unfolded Protein Response-Mediated Autophagy in Prostate Cancer Cells: A TMT-Based Quantitative Proteomic Analysis

(2016) Liza J. Burton et al.   PLoS One

Cancer-associated fibroblasts promote non-small cell lung cancer cell invasion by upregulation of glucose-regulated protein 78 (GRP78) expression in an integrated bionic microfluidic device

(2016) Ting Yu et al.   Oncotarget

Prostate cancer and the unfolded protein response

(2016) Margrethe Storm et al.   Oncotarget

Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model

(2016) Leena Hilakivi-Clarke et al.   JNCI-Journal of the National Cancer Institute

Spliced XBP1 promotes macrophage survival and autophagy by interacting with Beclin-1

(2015) Ping-Ge Tian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth

(2015) Hejing Huang et al.   CANCER LETTERS

Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response

(2015) K. Bartkowiak et al.   CANCER RESEARCH

The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?

(2015) Vicki Plaks et al.   Cell Stem Cell

Divergent androgen regulation of unfolded protein response pathways drives prostate cancer

(2015) X. Sheng et al.   EMBO Molecular Medicine

Celastrol induces unfolded protein response-dependent cell death in head and neck cancer

(2015) Andrew M. Fribley et al.   EXPERIMENTAL CELL RESEARCH

CD8+T Cell Exhaustion, Suppressed Gamma Interferon Production, and Delayed Memory Response Induced by Chronic Brucella melitensis Infection

(2015) Marina Durward-Diioia et al.   INFECTION AND IMMUNITY

Taxol-induced unfolded protein response activation in breast cancer cells exposed to hypoxia: ATF4 activation regulates autophagy and inhibits apoptosis

(2015) Annick Notte et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

(2015) Douglas Marvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Suppression of cancer relapse and metastasis by inhibiting cancer stemness

(2015) Youzhi Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

(2015) Mark A. Feitelson et al.   SEMINARS IN CANCER BIOLOGY

Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapy

(2015) Feven Tameire et al.   SEMINARS IN CANCER BIOLOGY

Controlling the unfolded protein response-mediated life and death decisions in cancer

(2015) Marion Maurel et al.   SEMINARS IN CANCER BIOLOGY

Overcoming T cell exhaustion in infection and cancer

(2015) Kristen E. Pauken et al.   TRENDS IN IMMUNOLOGY

T-cell exhaustion in the tumor microenvironment

(2015) Y Jiang et al.   Cell Death & Disease

Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis

(2015) Alpa Sidhu et al.   ACS Medicinal Chemistry Letters

Tumors: Wounds That Do Not Heal--Redux

(2015) H. F. Dvorak   Cancer Immunology Research

Phenotyping of tumor-associated macrophages in colorectal cancer: Impact on single cell invasion (tumor budding) and clinicopathological outcome

(2015) Viktor H. Koelzer et al.   OncoImmunology

Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth

(2015) Kazuyoshi Shiga et al.   Cancers

Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers

(2015) Robert Clarke et al.   Frontiers in Oncology

Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells

(2015) Wenwen Chien et al.   Oncotarget

Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells

(2014) Nameeta Mujumdar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The unfolded protein response as a target for cancer therapy

(2014) Anika Nagelkerke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Inhibition of Cancer Cell Growth by GRP78 siRNA Lipoplex via Activation of Unfolded Protein Response

(2014) Kazushi Matsumura et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer

(2014) Minghua Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metastases in Immune-Mediated Dormancy: A New Opportunity for Targeting Cancer

(2014) I. Romero et al.   CANCER RESEARCH

Targeting Cancer Cells via the Reactive Oxygen Species-Mediated Unfolded Protein Response with a Novel Synthetic Polyphenol Conjugate

(2014) S. Y. Shin et al.   CLINICAL CANCER RESEARCH

Knockdown of estrogen receptor-α induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation, promoting ROS-induced breast cancer cell death

(2014) Katherine L. Cook et al.   FASEB JOURNAL

Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

(2014) Evgeniy B. Eruslanov et al.   JOURNAL OF CLINICAL INVESTIGATION

Endoplasmic Reticulum Stress Regulator XBP-1 Contributes to Effector CD8+ T Cell Differentiation during Acute Infection

(2014) D. Kamimura et al.   JOURNAL OF IMMUNOLOGY

Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3α/β regulate foam cell formation

(2014) Cameron S. McAlpine et al.   JOURNAL OF LIPID RESEARCH

Chemical Induction of Unfolded Protein Response Enhances Cancer Cell Killing through Lytic Virus Infection

(2014) V. Prasad et al.   JOURNAL OF VIROLOGY

The unfolded protein response potentiates epithelial-to-mesenchymal transition (EMT) of gastric cancer cells under severe hypoxic conditions

(2014) Xinsheng Shen et al.   MEDICAL ONCOLOGY

MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer

(2014) Ayesha N Shajahan-Haq et al.   Molecular Cancer

The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells

(2014) Fabiola Osorio et al.   NATURE IMMUNOLOGY

Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor α-positive breast cancer

(2014) N Andruska et al.   ONCOGENE

Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability

(2014) Paul E. Harrington et al.   ACS Medicinal Chemistry Letters

A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients

(2014) Meiying Zhang et al.   Journal of Ovarian Research

GRP78 secreted by tumor cells stimulates differentiation of bone marrow mesenchymal stem cells to cancer-associated fibroblasts

(2013) Yanan Peng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Berberine combined with 2-deoxy-d-glucose synergistically enhances cancer cell proliferation inhibition via energy depletion and unfolded protein response disruption

(2013) Li-xia Fan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis

(2013) Quan Qiu et al.   EMBO JOURNAL

Targeting GRP78 and antiestrogen resistance in breast cancer

(2013) Katherine L Cook et al.   Future Medicinal Chemistry

The unfolded protein response regulator GRP78 is a novel predictive biomarker in colorectal cancer

(2013) Michael Thornton et al.   INTERNATIONAL JOURNAL OF CANCER

C/EBP Homologous Protein-induced Macrophage Apoptosis Protects Mice from Steatohepatitis

(2013) Harmeet Malhi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic Reticulum Stress Promotes Macrophage-derived Foam Cell Formation by Up-regulating Cluster of Differentiation 36 (CD36) Expression

(2013) Shutong Yao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

The UPR in atherosclerosis

(2013) Alex X. Zhou et al.   Seminars in Immunopathology

Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption

(2013) Ritesh K. Srivastava et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Macrophages

(2013) Sofia Edin et al.   OncoImmunology

The Tumor Microenvironment: A Pitch for Multiple Players

(2013) Giovanna Schiavoni et al.   Frontiers in Oncology

Minimally modified low-density lipoprotein induces macrophage endoplasmic reticulum stress via toll-like receptor 4

(2012) Shutong Yao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Endoplasmic Reticulum Stress, the Unfolded Protein Response, Autophagy, and the Integrated Regulation of Breast Cancer Cell Fate

(2012) R. Clarke et al.   CANCER RESEARCH

Tumor-infiltrating regulatory T cells delineated by upregulation of PD-1 and inhibitory receptors

(2012) Hyo Jin Park et al.   CELLULAR IMMUNOLOGY

Endoplasmic reticulum stress and its regulator XBP-1 contributes to dendritic cell maturation and activation induced by high mobility group box-1 protein

(2012) Xiao-mei Zhu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

(2012) B Luo et al.   ONCOGENE

A Peptidic Unconjugated GRP78/BiP Ligand Modulates the Unfolded Protein Response and Induces Prostate Cancer Cell Death

(2012) Danilo Maddalo et al.   PLoS One

Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature

(2012) Qiong-wen Zhang et al.   PLoS One

Tumor associated regulatory dendritic cells

(2012) Yang Ma et al.   SEMINARS IN CANCER BIOLOGY

Trial watch

(2012) Laura Senovilla et al.   OncoImmunology

Regulatory dendritic cells: New targets for cancer immunotherapy

(2011) Michael R. Shurin et al.   CANCER BIOLOGY & THERAPY

Tumor-Associated Macrophages Mediate Immunosuppression in the Renal Cancer Microenvironment by Activating the 15-Lipoxygenase-2 Pathway

(2011) I. Daurkin et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

ER stress and its regulator X-box-binding protein-1 enhance polyIC-induced innate immune response in dendritic cells

(2011) Fanlei Hu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes

(2011) Suleiman A Isa et al.   Lipids in Health and Disease

 B-Crystallin, an Effector of Unfolded Protein Response, Confers Anti-VEGF Resistance to Breast Cancer via Maintenance of Intracrine VEGF in Endothelial Cells

(2011) Q. Ruan et al.   MOLECULAR CANCER RESEARCH

Tumor-Associated Macrophages Recruit CCR6+ Regulatory T Cells and Promote the Development of Colorectal Cancer via Enhancing CCL20 Production in Mice

(2011) Jinlin Liu et al.   PLoS One

Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells

(2011) N. R. Mahadevan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

(2011) B. M. Gardner et al.   SCIENCE

Elusive Identities and Overlapping Phenotypes of Proangiogenic Myeloid Cells in Tumors

(2010) Seth B. Coffelt et al.   AMERICAN JOURNAL OF PATHOLOGY

Microarray analysis of nemorosone-induced cytotoxic effects on pancreatic cancer cells reveals activation of the unfolded protein response (UPR)

(2010) Frank Holtrup et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intratumoral forkhead box P3-positive regulatory T cells predict poor survival in cyclooxygenase-2-positive uveal melanoma

(2010) Dimitrios Mougiakakos et al.   CANCER

Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity

(2010) David G. DeNardo et al.   CANCER AND METASTASIS REVIEWS

Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis

(2010) Ansgar Brüning et al.   CANCER BIOLOGY & THERAPY

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Molecular Pathways Linking Inflammation and Cancer

(2010) A. Mantovani   CURRENT MOLECULAR MEDICINE

Tumors as Organs: Complex Tissues that Interface with the Entire Organism

(2010) Mikala Egeblad et al.   DEVELOPMENTAL CELL

Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions

(2010) Jeffrey G. Dickhout et al.   FASEB JOURNAL

Dual Roles for Immunity in Gastrointestinal Cancers

(2010) Cristina Ferrone et al.   JOURNAL OF CLINICAL ONCOLOGY

Discovery of a Novel Unfolded Protein Response Phenotype of Cancer Stem/Progenitor Cells from the Bone Marrow of Breast Cancer Patients

(2010) Kai Bartkowiak et al.   JOURNAL OF PROTEOME RESEARCH

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression

(2010) Jane C. Goodall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Lymphoidlike Stroma and Immune Escape by Tumors That Express the Chemokine CCL21

(2010) J. D. Shields et al.   SCIENCE

Macrophage Apoptosis in Advanced Atherosclerosis

(2009) Ira Tabas et al.   Annals of the New York Academy of Sciences

Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78

(2009) U. K. Misra et al.   APOPTOSIS

Activation and clinical significance of the unfolded protein response in breast cancer

(2009) P Scriven et al.   BRITISH JOURNAL OF CANCER

The unfolded protein response during prostate cancer development

(2009) Alex Yick-Lun So et al.   CANCER AND METASTASIS REVIEWS

Chemical Genomics Identifies the Unfolded Protein Response as a Target for Selective Cancer Cell Killing during Glucose Deprivation

(2009) S. Saito et al.   CANCER RESEARCH

Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance

(2009) R. Ye et al.   DIABETES

Cellular and molecular pathways linking inflammation and cancer

(2009) Chiara Porta et al.   IMMUNOBIOLOGY

Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response

(2009) Jiao Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Tumor-Educated CD11b high Ia low Regulatory Dendritic Cells Suppress T Cell Response through Arginase I

(2009) Qiuyan Liu et al.   JOURNAL OF IMMUNOLOGY

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

(2009) G. Solinas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE

Endoplasmic Reticulum Stress in Disease Pathogenesis

(2008) Jonathan H. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Polarized immune responses differentially regulate cancer development

(2008) Magnus Johansson et al.   IMMUNOLOGICAL REVIEWS

Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer

(2008) Michael P.A. Davies et al.   INTERNATIONAL JOURNAL OF CANCER

B- and T-cell Development Both Involve Activity of the Unfolded Protein Response Pathway

(2008) Ryan Brunsing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immune-mediated dormancy: an equilibrium with cancer

(2008) Michele W. L. Teng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cancer as an overhealing wound: an old hypothesis revisited

(2008) Matthias Schäfer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY