Chemical Induction of Unfolded Protein Response Enhances Cancer Cell Killing through Lytic Virus Infection

Viruses for Tumor Therapy

(2014) John Bell et al.   Cell Host & Microbe

Innate Immunity to Adenovirus

(2014) Rodinde Hendrickx et al.   HUMAN GENE THERAPY

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

(2014) Xi Chen et al.   NATURE

siPools: highly complex but accurately defined siRNA pools eliminate off-target effects

(2014) Michael Hannus et al.   NUCLEIC ACIDS RESEARCH

Epithelial-to-Mesenchymal Transition Activates PERK-eIF2  and Sensitizes Cells to Endoplasmic Reticulum Stress

(2014) Y.-x. Feng et al.   Cancer Discovery

Tracking Viral Genomes in Host Cells at Single-Molecule Resolution

(2013) I-Hsuan Wang et al.   Cell Host & Microbe

RETRACTED: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling

(2013) Jin A. Cho et al.   Cell Host & Microbe

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

Gene therapy clinical trials worldwide to 2012 - an update

(2013) Samantha L. Ginn et al.   JOURNAL OF GENE MEDICINE

A Direct and Versatile Assay Measuring Membrane Penetration of Adenovirus in Single Cells

(2013) M. Suomalainen et al.   JOURNAL OF VIROLOGY

New viruses for cancer therapy: meeting clinical needs

(2013) Tanner S. Miest et al.   NATURE REVIEWS MICROBIOLOGY

Synergistic cytotoxicity of radiation and oncolytic Lister strain vaccinia in V600D/EBRAF mutant melanoma depends on JNK and TNF-α signaling

(2013) J N Kyula et al.   ONCOGENE

Advances in stem cell therapy against gliomas

(2013) M. Sarah S. Bovenberg et al.   TRENDS IN MOLECULAR MEDICINE

SPOC1-Mediated Antiviral Host Cell Response Is Antagonized Early in Human Adenovirus Type 5 Infection

(2013) Sabrina Schreiner et al.   PLoS Pathogens

Adenoviruses - from pathogens to therapeutics: a report on the 10th International Adenovirus Meeting

(2012) Urs F. Greber et al.   CELLULAR MICROBIOLOGY

Adenovirus signalling in entry

(2012) Nina Wolfrum et al.   CELLULAR MICROBIOLOGY

Radiovirotherapy: Principles and Prospects in Oncology

(2012) Y. Touchefeu et al.   CURRENT PHARMACEUTICAL DESIGN

Cell-Free Transmission of Human Adenovirus by Passive Mass Transfer in Cell Culture Simulated in a Computer Model

(2012) Artur Yakimovich et al.   JOURNAL OF VIROLOGY

The Adenoviral Oncogene E1A-13S Interacts with a Specific Isoform of the Tumor Suppressor PML To Enhance Viral Transcription

(2012) J. Berscheminski et al.   JOURNAL OF VIROLOGY

Characterization of the 55-Residue Protein Encoded by the 9S E1A mRNA of Species C Adenovirus

(2012) Matthew S. Miller et al.   JOURNAL OF VIROLOGY

Ad3-hTERT-E1A, a Fully Serotype 3 Oncolytic Adenovirus, in Patients With Chemotherapy Refractory Cancer

(2012) Otto Hemminki et al.   MOLECULAR THERAPY

Oncolytic virotherapy

(2012) Stephen J Russell et al.   NATURE BIOTECHNOLOGY

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

(2012) B. C. S. Cross et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRE1  Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2

(2012) J.-P. Upton et al.   SCIENCE

Niclosamide Is a Proton Carrier and Targets Acidic Endosomes with Broad Antiviral Effects

(2012) Andreas Jurgeit et al.   PLoS Pathogens

Virus-Tumor Interactome Screen Reveals ER Stress Response Can Reprogram Resistant Cancers for Oncolytic Virus-Triggered Caspase-2 Cell Death

(2011) Douglas J. Mahoney et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Kinesin-1-Mediated Capsid Disassembly and Disruption of the Nuclear Pore Complex Promote Virus Infection

(2011) Sten Strunze et al.   Cell Host & Microbe

Drifting Motions of the Adenovirus Receptor CAR and Immobile Integrins Initiate Virus Uncoating and Membrane Lytic Protein Exposure

(2011) Christoph J. Burckhardt et al.   Cell Host & Microbe

Functional Genetic and Biophysical Analyses of Membrane Disruption by Human Adenovirus

(2011) C. L. Moyer et al.   JOURNAL OF VIROLOGY

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

The Unfolded Protein Response: Integrating Stress Signals Through the Stress Sensor IRE1α

(2011) Claudio Hetz et al.   PHYSIOLOGICAL REVIEWS

Chemotactic antiviral cytokines promote infectious apical entry of human adenovirus into polarized epithelial cells

(2011) Verena Lütschg et al.   Nature Communications

Oncolytic (replication-competent) adenoviruses as anticancer agents

(2010) Karoly Toth et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Differential Effects of the Putative GBF1 Inhibitors Golgicide A and AG1478 on Enterovirus Replication

(2010) L. van der Linden et al.   JOURNAL OF VIROLOGY

Stepwise Loss of Fluorescent Core Protein V from Human Adenovirus during Entry into Cells

(2010) D. Puntener et al.   JOURNAL OF VIROLOGY

An RNA replication-center assay for high content image-based quantifications of human rhinovirus and coxsackievirus infections

(2010) Andreas Jurgeit et al.   Virology Journal

Increasing the Efficacy of Oncolytic Adenovirus Vectors

(2010) Karoly Toth et al.   Viruses-Basel

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

Adenovirus Transport via Direct Interaction of Cytoplasmic Dynein with the Viral Capsid Hexon Subunit

(2009) K. Helen Bremner et al.   Cell Host & Microbe

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

(2009) Julie Hollien et al.   JOURNAL OF CELL BIOLOGY

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

(2009) Kasper M.A. Rouschop et al.   JOURNAL OF CLINICAL INVESTIGATION

Golgicide A reveals essential roles for GBF1 in Golgi assembly and function

(2009) José B Sáenz et al.   Nature Chemical Biology

Intrinsic Structural Disorder in Adenovirus E1A: a Viral Molecular Hub Linking Multiple Diverse Processes

(2008) P. Pelka et al.   JOURNAL OF VIROLOGY

Unfolded protein response and cell death after depletion of brefeldin A-inhibited guanine nucleotide-exchange protein GBF1

(2008) C. Citterio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenovirus Small e1a Alters Global Patterns of Histone Modification

(2008) G. A. Horwitz et al.   SCIENCE

Key Role of Splenic Myeloid DCs in the IFN-αβ Response to Adenoviruses In Vivo

(2008) György Fejer et al.   PLoS Pathogens