Bioengineering strategies for nephrologists: kidney was not built in a day

Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats

(2019) Teppei Goto et al.   Nature Communications

Renal reabsorption in 3D vascularized proximal tubule models

(2019) Neil Y. C. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flow-enhanced vascularization and maturation of kidney organoids in vitro

(2019) Kimberly A. Homan et al.   NATURE METHODS

Tubuloids derived from human adult kidney and urine for personalized disease modeling

(2019) Frans Schutgens et al.   NATURE BIOTECHNOLOGY

Kidney Xenotransplantation

(2019) Brian I. Shaw et al.   Clinical Journal of the American Society of Nephrology

A human proximal tubule-on-a-chip to study renal disease and toxicity

(2019) Courtney M. Sakolish et al.   Biomicrofluidics

Long-Term Survival of Pig-to-Rhesus Macaque Renal Xenografts is Dependent on CD4 T cell Depletion

(2019) S C Kim et al.   AMERICAN JOURNAL OF TRANSPLANTATION

OPTN/SRTR 2017 Annual Data Report: Kidney

(2019) A. Hart et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Engineering the vasculature of decellularized rat kidney scaffolds using human induced pluripotent stem cell-derived endothelial cells

(2019) Osele Ciampi et al.   Scientific Reports

In vivo regeneration of interspecies chimeric kidneys using a nephron progenitor cell replacement system

(2019) Toshinari Fujimoto et al.   Scientific Reports

Directed differentiation of human induced pluripotent stem cells into mature stratified bladder urothelium

(2019) Kotaro Suzuki et al.   Scientific Reports

Kidney organoids: accurate models or fortunate accidents

(2019) Melissa H. Little et al.   GENES & DEVELOPMENT

iPSC-Derived Embryoid Bodies as Models of c-Met-Mutated Hereditary Papillary Renal Cell Carcinoma

(2019) Jin Wook Hwang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Kidney Regeneration in Later-Stage Mouse Embryos via Transplanted Renal Progenitor Cells

(2019) Shuichiro Yamanaka et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Human kidney organoids: progress and remaining challenges

(2019) Ryuichi Nishinakamura   Nature Reviews Nephrology

Bioink formulations to ameliorate bioprinting-induced loss of cellular viability

(2019) Sudipto Datta et al.   Biointerphases

Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells

(2019) Munemasa Mori et al.   NATURE MEDICINE

Generation of infant- and pediatric-derived urinary induced pluripotent stem cells competent to form kidney organoids

(2019) Jaap Mulder et al.   PEDIATRIC RESEARCH

A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

(2019) Astgik Petrosyan et al.   Nature Communications

3D bioprinting of tissues and organs for regenerative medicine

(2018) Sanjairaj Vijayavenkataraman et al.   ADVANCED DRUG DELIVERY REVIEWS

Development of a microfluidic system comprising dialysis and secretion components for a bioassay of renal clearance

(2018) Yu SAKUTA et al.   ANALYTICAL SCIENCES

Kidney-on-a-Chip: A New Technology for Predicting Drug Efficacy, Interactions, and Drug-induced Nephrotoxicity

(2018) Jeonghwan Lee et al.   CURRENT DRUG METABOLISM

From portable dialysis to a bioengineered kidney

(2018) Maaike K. van Gelder et al.   Expert Review of Medical Devices

Biocompatibility and hemocompatibility of efficiently decellularized whole porcine kidney for tissue engineering

(2018) Kamal Hany Hussein et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip

(2018) Samira Musah et al.   Nature Protocols

Upregulation of CD80 on glomerular podocytes plays an important role in development of proteinuria following pig-to-baboon xeno-renal transplantation - an experimental study

(2018) Christopher J. Rivard et al.   TRANSPLANT INTERNATIONAL

Segmental Additive Tissue Engineering

(2018) Martina Sladkova et al.   Scientific Reports

Bioinks for 3D bioprinting: an overview

(2018) P. Selcan Gungor-Ozkerim et al.   Biomaterials Science

Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo

(2018) Cathelijne W. van den Berg et al.   Stem Cell Reports

Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip

(2018) Jelle Vriend et al.   AAPS Journal

Innovations in Wearable and Implantable Artificial Kidneys

(2018) Megha Salani et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Evaluation of the host immune response to decellularized lung scaffolds derived from α-Gal knockout pigs in a non-human primate model

(2018) Elizabeth C. Stahl et al.   BIOMATERIALS

Concept and Computational Design for a Bioartificial Nephron-On-A-Chip

(2018) E. Weinberg et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip

(2018) Courtney Sakolish et al.   Scientific Reports

Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes

(2018) Shunsuke Tanigawa et al.   Stem Cell Reports

Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Gene Editing Technique in Xenotransplantation

(2018) Meisam Naeimi Kararoudi et al.   Frontiers in Immunology

Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics

(2018) Haojia Wu et al.   Cell Stem Cell

Kidney-on-a-chip: untapped opportunities

(2018) Nureddin Ashammakhi et al.   KIDNEY INTERNATIONAL

Evaluation of variability in human kidney organoids

(2018) Belinda Phipson et al.   NATURE METHODS

Tomorrow today: organ-on-a-chip advances towards clinically relevant pharmaceutical and medical in vitro models

(2018) Mario Rothbauer et al.   CURRENT OPINION IN BIOTECHNOLOGY

A disease model of diabetic nephropathy in a glomerulus-on-a-chip microdevice

(2017) Li Wang et al.   LAB ON A CHIP

Interspecies organogenesis generates autologous functional islets

(2017) Tomoyuki Yamaguchi et al.   NATURE

3D bioprinting using stem cells

(2017) Chin Siang Ong et al.   PEDIATRIC RESEARCH

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

(2017) Dong Niu et al.   SCIENCE

Asymmetric BMP4 signalling improves the realism of kidney organoids

(2017) Christopher G. Mills et al.   Scientific Reports

3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing

(2017) Shelby M. King et al.   Frontiers in Physiology

Experimental Evaluation of Kidney Regeneration by Organ Scaffold Recellularization

(2017) Andrea Remuzzi et al.   Scientific Reports

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle

(2017) Lawrence Vernetti et al.   Scientific Reports

First Implantation of Silicon Nanopore Membrane Hemofilters

(2016) Clark Kensinger et al.   ASAIO JOURNAL

3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors

(2016) Zhongwei Li et al.   Cell Stem Cell

Molecular Criteria for Defining the Naive Human Pluripotent State

(2016) Thorold W. Theunissen et al.   Cell Stem Cell

Kidney-on-a-chip technology for renal proximal tubule tissue reconstruction

(2016) Tom T.G. Nieskens et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Development of a wearable bioartificial kidney using the Bioartificial Renal Epithelial Cell System (BRECS)

(2016) Kimberly A. Johnston et al.   Journal of Tissue Engineering and Regenerative Medicine

Development of a microphysiological model of human kidney proximal tubule function

(2016) Elijah J. Weber et al.   KIDNEY INTERNATIONAL

Stem cells and interspecies chimaeras

(2016) Jun Wu et al.   NATURE

Diffusive Silicon Nanopore Membranes for Hemodialysis Applications

(2016) Steven Kim et al.   PLoS One

Kidney-on-a-Chip Technology for Drug-Induced Nephrotoxicity Screening

(2016) Martijn J. Wilmer et al.   TRENDS IN BIOTECHNOLOGY

Susceptibility of porcine endogenous retrovirus to anti-retroviral inhibitors

(2016) Takele Argaw et al.   XENOTRANSPLANTATION

Development of a Functional Glomerulus at the Organ Level on a Chip to Mimic Hypertensive Nephropathy

(2016) Mengying Zhou et al.   Scientific Reports

Functional Kidney Bioengineering with Pluripotent Stem-Cell-Derived Renal Progenitor Cells and Decellularized Kidney Scaffolds

(2016) Chan Du et al.   Advanced Healthcare Materials

Bioengineered kidney tubules efficiently excrete uremic toxins

(2016) J. Jansen et al.   Scientific Reports

Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips

(2016) Kimberly A. Homan et al.   Scientific Reports

Translational value of animal models of kidney failure

(2015) Alberto Ortiz et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro

(2015) M. Adler et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Human Urine-Derived Renal Progenitors for Personalized Modeling of Genetic Kidney Disorders

(2015) E. Lazzeri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Maintenance Dialysis throughout the World in Years 1990 and 2010

(2015) B. Thomas et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

(2015) Ilka Maschmeyer et al.   LAB ON A CHIP

Worldwide access to treatment for end-stage kidney disease: a systematic review

(2015) Thaminda Liyanage et al.   LANCET

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

Urine excretion strategy for stem cell-generated embryonic kidneys

(2015) Shinya Yokote et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Organ Generation UsingMixl1-Inducible Mouse Pluripotent Stem Cells in Blastocyst Complementation

(2015) Toshihiro Kobayashi et al.   STEM CELLS AND DEVELOPMENT

Pig kidney graft survival in a baboon for 136 days: longest life-supporting organ graft survival to date

(2015) Hayato Iwase et al.   XENOTRANSPLANTATION

Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model

(2015) Laura Higginbotham et al.   XENOTRANSPLANTATION

Regulatory aspects of clinical xenotransplantation

(2015) Henk-Jan Schuurman   International Journal of Surgery

Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells

(2015) Damien Maggiorani et al.   PLoS One

Natural Scaffolds for Renal Differentiation of Human Embryonic Stem Cells for Kidney Tissue Engineering

(2015) Cynthia A. Batchelder et al.   PLoS One

Optimization and Critical Evaluation of Decellularization Strategies to Develop Renal Extracellular Matrix Scaffolds as Biological Templates for Organ Engineering and Transplantation

(2014) M. Caralt et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

A bio-artificial renal epithelial cell system conveys survival advantage in a porcine model of septic shock

(2014) Angela J. Westover et al.   Journal of Tissue Engineering and Regenerative Medicine

A Bioartificial Renal Tubule Device Embedding Human Renal Stem/Progenitor Cells

(2014) Anna Giovanna Sciancalepore et al.   PLoS One

Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia

(2014) V. Raghavan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bioengineering Dermo-Epidermal Skin Grafts with Blood and Lymphatic Capillaries

(2014) D. Marino et al.   Science Translational Medicine

Induction of epithelial-to-mesenchymal transition in proximal tubular epithelial cells on microfluidic devices

(2013) Mengying Zhou et al.   BIOMATERIALS

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

(2013) Kyung-Jin Jang et al.   Integrative Biology

Human embryonic stem cells differentiate into functional renal proximal tubular–like cells

(2013) Karthikeyan Narayanan et al.   KIDNEY INTERNATIONAL

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

Regeneration and experimental orthotopic transplantation of a bioengineered kidney

(2013) Jeremy J Song et al.   NATURE MEDICINE

The glomerular basement membrane as a barrier to albumin

(2013) Jung Hee Suh et al.   Nature Reviews Nephrology

Tissue Specificity of Decellularized Rhesus Monkey Kidney and Lung Scaffolds

(2013) Karina H. Nakayama et al.   PLoS One

Sustained Release of BMP-2 in Bioprinted Alginate for Osteogenicity in Mice and Rats

(2013) Michelle T. Poldervaart et al.   PLoS One

Recellularization of Well-Preserved Acellular Kidney Scaffold Using Embryonic Stem Cells

(2013) Barbara Bonandrini et al.   TISSUE ENGINEERING PART A

Generation of Kidney from Pluripotent Stem Cells via Blastocyst Complementation

(2012) Jo-ichi Usui et al.   AMERICAN JOURNAL OF PATHOLOGY

Podocyte Biology and Pathogenesis of Kidney Disease

(2012) Jochen Reiser et al.   Annual Review of Medicine

Investigation of ifosfamide nephrotoxicity induced in a liver-kidney co-culture biochip

(2012) Leila Choucha-Snouber et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evaluation of hydrogels for bio-printing applications

(2012) Sean V. Murphy et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Engineering of polarized tubular structures in a microfluidic device to study calcium phosphate stone formation

(2012) Zengjiang Wei et al.   LAB ON A CHIP

The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule

(2012) Sarah E. Jenkinson et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Direct Human Cartilage Repair Using Three-Dimensional Bioprinting Technology

(2012) Xiaofeng Cui et al.   TISSUE ENGINEERING PART A

Bioprinted Amniotic Fluid-Derived Stem Cells Accelerate Healing of Large Skin Wounds

(2012) Aleksander Skardal et al.   Stem Cells Translational Medicine

An overview of tissue and whole organ decellularization processes

(2011) Peter M. Crapo et al.   BIOMATERIALS

Albumin handling by renal tubular epithelial cells in a microfluidic bioreactor

(2011) Nicholas Ferrell et al.   BIOTECHNOLOGY AND BIOENGINEERING

Formation of a thymus from rat ES cells in xenogeneic nude mouse↔rat ES chimeras

(2011) Ayako Isotani et al.   GENES TO CELLS

Renal Tissue Engineering with Decellularized Rhesus Monkey Kidneys: Age-Related Differences

(2011) Karina H. Nakayama et al.   TISSUE ENGINEERING PART A

Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells

(2010) Toshihiro Kobayashi et al.   CELL

Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice

(2010) Silvia Espejel et al.   JOURNAL OF CLINICAL INVESTIGATION

Late-term results of tissue-engineered vascular grafts in humans

(2010) Narutoshi Hibino et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Notch Activation Differentially Regulates Renal Progenitors Proliferation and Differentiation Toward the Podocyte Lineage in Glomerular Disorders

(2010) Laura Lasagni et al.   STEM CELLS

Embryonic Stem Cells Proliferate and Differentiate when Seeded into Kidney Scaffolds

(2009) E. A. Ross et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Implantable Artificial Kidney

(2009) William H. Fissell et al.   SEMINARS IN DIALYSIS

High-performance silicon nanopore hemofiltration membranes

(2008) William H. Fissell et al.   JOURNAL OF MEMBRANE SCIENCE

Efficacy and Safety of Renal Tubule Cell Therapy for Acute Renal Failure

(2008) J. Tumlin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regeneration of Glomerular Podocytes by Human Renal Progenitors

(2008) E. Ronconi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Stem cells in the embryonic kidney

(2008) R. Nishinakamura   KIDNEY INTERNATIONAL

Two-step oligoclonal development of male germ cells

(2008) H. Ueno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA