A human proximal tubule-on-a-chip to study renal disease and toxicity

A novel microfluidic device to model the human proximal tubule and glomerulus

(2017) Courtney M. Sakolish et al.   RSC Advances

A microfluidic renal proximal tubule with active reabsorptive function

(2017) Else M. Vedula et al.   PLoS One

Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function

(2016) SY Chang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Development of a microphysiological model of human kidney proximal tubule function

(2016) Elijah J. Weber et al.   KIDNEY INTERNATIONAL

The Flaws and Human Harms of Animal Experimentation

(2015) AYSHA AKHTAR   CAMBRIDGE QUARTERLY OF HEALTHCARE ETHICS

Preparation, characterization, and in vitro cytotoxicity of COM and COD crystals with various sizes

(2015) Xin-Yuan Sun et al.   Materials Science & Engineering C-Materials for Biological Applications

Neutrophil gelatinase-associated lipocalin and innate immune responses to bacterial infections

(2015) Dimitrios Nasioudis et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Drug-Induced Nephrotoxicity: Clinical Impact and Preclinical in Vitro Models

(2014) Ho Yee Tiong et al.   MOLECULAR PHARMACEUTICS

Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia

(2014) V. Raghavan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Noninvasive Biomarkers for Nephrotoxicity Using HK-2 Human Kidney Epithelial Cells

(2014) Sun Young Kim et al.   TOXICOLOGICAL SCIENCES

Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner

(2014) Alexander Birbrair et al.   Stem Cell Research & Therapy

Precompetitive consortium approach to validation of the next generation of biomarkers in schizophrenia

(2013) Colin T Dourish et al.   Biomarkers in Medicine

Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment

(2013) Kyung-Jin Jang et al.   Integrative Biology

Animal models of chronic kidney disease: useful but not perfect

(2013) G. J. Becker et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

In vitro evaluation of biomarkers for cisplatin-induced nephrotoxicity using HK-2 human kidney epithelial cells

(2013) So-Jung Sohn et al.   TOXICOLOGY LETTERS

Epithelial-mesenchymal transition and fibrosis are mutually exclusive reponses in shear-activated proximal tubular epithelial cells

(2012) Bryan M. Grabias et al.   FASEB JOURNAL

The role of IL-7 in renal proximal tubule epithelial cells fibrosis

(2012) Pei-fang Hsieh et al.   MOLECULAR IMMUNOLOGY

Actin Structure and Function

(2011) Roberto Dominguez et al.   Annual Review of Biophysics

Cellular and molecular mechanisms of renal fibrosis

(2011) Youhua Liu   Nature Reviews Nephrology

Neutrophil gelatinase-associated lipocalin: a  promising biomarker for human acute kidney injury

(2010) Prasad Devarajan   Biomarkers in Medicine

Comparison of the novel HK-2 human renal proximal tubular cell line with the standard LLC-PK1 cell line in studying drug-induced nephrotoxicity

(2010) Patrina Gunness et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Fluid-shear-stress-induced translocation of aquaporin-2 and reorganization of actin cytoskeleton in renal tubular epithelial cells

(2010) Kyung-Jin Jang et al.   Integrative Biology

Permeability–selectivity analysis for ultrafiltration: Effect of pore geometry

(2009) Dharmesh M. Kanani et al.   JOURNAL OF MEMBRANE SCIENCE

Differential proteomic analysis of cyclosporine A-induced toxicity in renal proximal tubule cells

(2009) M. Puigmule et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Shear-induced reorganization of renal proximal tubule cell actin cytoskeleton and apical junctional complexes

(2008) Y. Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA