- Home
- Publications
- Publication Search
- Publication Details
Title
Regulation of translesion DNA synthesis in mammalian cells
Authors
Keywords
-
Journal
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-01-26
DOI
10.1002/em.22359
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching
- (2019) Masataka Tsuda et al. PLoS One
- Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen
- (2019) Mark Hedglin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A PolH transcript with a short 3'UTR enhances PolH expression and mediates cisplatin resistance
- (2019) Jin Zhang et al. CANCER RESEARCH
- A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy
- (2019) Jessica L. Wojtaszek et al. CELL
- DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy
- (2019) Bas Pilzecker et al. NUCLEIC ACIDS RESEARCH
- Translesion and Repair DNA Polymerases: Diverse Structure and Mechanism
- (2018) Wei Yang et al. Annual Review of Biochemistry
- Long non-coding RNA ROR promotes radioresistance in hepatocelluar carcinoma cells by acting as a ceRNA for microRNA-145 to regulate RAD18 expression
- (2018) Ying Chen et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2–Ubiquitin Interaction
- (2018) Murugendra Vanarotti et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender
- (2018) Vikash Jha et al. JOURNAL OF MOLECULAR BIOLOGY
- RNA-splicing factor SART3 regulates translesion DNA synthesis
- (2018) Min Huang et al. NUCLEIC ACIDS RESEARCH
- PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress
- (2018) Emily M Schleicher et al. NUCLEIC ACIDS RESEARCH
- p15PAF binding to PCNA modulates the DNA sliding surface
- (2018) Matteo De March et al. NUCLEIC ACIDS RESEARCH
- Maneuvers on PCNA Rings during DNA Replication and Repair
- (2018) Dea Slade Genes
- Mechanisms of DNA Damage Tolerance: Post-Translational Regulation of PCNA
- (2018) Wendy Leung et al. Genes
- Ubiquitome Analysis Reveals PCNA-Associated Factor 15 (PAF15) as a Specific Ubiquitination Target of UHRF1 in Embryonic Stem Cells
- (2017) Elisabeth Karg et al. JOURNAL OF MOLECULAR BIOLOGY
- Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork
- (2017) Katherine N. Choe et al. MOLECULAR CELL
- FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2
- (2017) Antonio Porro et al. Nature Communications
- Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis
- (2017) Xiaolu Ma et al. Nature Communications
- Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?
- (2017) Kinrin Yamanaka et al. PLoS Genetics
- Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases
- (2017) Linlin Zhao et al. Genes
- Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases
- (2017) Ryan Barnes et al. Genes
- Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis
- (2016) Yulia Pustovalova et al. BIOCHEMISTRY
- REV1 promotes PCNA monoubiquitylation through interacting with ubiquitylated RAD18
- (2016) Zhifeng Wang et al. JOURNAL OF CELL SCIENCE
- The Functions of Serine 687 Phosphorylation of Human DNA Polymerase η in UV Damage Tolerance
- (2016) Xiaoxia Dai et al. MOLECULAR & CELLULAR PROTEOMICS
- USP7 is a SUMO deubiquitinase essential for DNA replication
- (2016) Emilio Lecona et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells
- (2016) Leticia K. Lerner et al. NUCLEIC ACIDS RESEARCH
- PCNA tool belts and polymerase bridges form during translesion synthesis
- (2016) Elizabeth M. Boehm et al. NUCLEIC ACIDS RESEARCH
- Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA
- (2016) Emmanuelle Despras et al. Nature Communications
- A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis
- (2016) Yanzhe Gao et al. Nature Communications
- USP7 is a SUMO deubiquitinase essential for DNA replication
- (2016) Emilio Lecona et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Regulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteins
- (2015) Justyna McIntyre et al. DNA REPAIR
- Eukaryotic DNA polymerase ζ
- (2015) Alena V. Makarova et al. DNA REPAIR
- Regulation of the Rev1-pol complex during bypass of a DNA interstrand cross-link
- (2015) M. Budzowska et al. EMBO JOURNAL
- Posttranslational Regulation of Human DNA Polymerase ι
- (2015) Justyna McIntyre et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- USP7 is essential for maintaining Rad18 stability and DNA damage tolerance
- (2015) A Zlatanou et al. ONCOGENE
- Relevance of Simultaneous Mono-Ubiquitinations of Multiple Units of PCNA Homo-Trimers in DNA Damage Tolerance
- (2015) Rie Kanao et al. PLoS One
- Enhanced expression of DNA polymerase eta contributes to cisplatin resistance of ovarian cancer stem cells
- (2015) Amit Kumar Srivastava et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis
- (2015) Janice Ortega et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor suppressor miR-145 reverses drug resistance by directly targeting DNA damage-related gene RAD18 in colorectal cancer
- (2015) Rui-Lei Liu et al. TUMOR BIOLOGY
- USP7 Is a Suppressor of PCNA Ubiquitination and Oxidative-Stress-Induced Mutagenesis in Human Cells
- (2015) Shu-ichiro Kashiwaba et al. Cell Reports
- DNA polymerase η is regulated by poly(rC)-binding protein 1 via mRNA stability
- (2014) Cong Ren et al. BIOCHEMICAL JOURNAL
- Translesion Polymerase Is Upregulated by Cancer Therapeutics and Confers Anticancer Drug Resistance
- (2014) M. T. Tomicic et al. CANCER RESEARCH
- The ADP-ribosyltransferase PARP10/ARTD10 Interacts with Proliferating Cell Nuclear Antigen (PCNA) and Is Required for DNA Damage Tolerance
- (2014) Claudia M. Nicolae et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis
- (2014) Michelle K. Zeman et al. JOURNAL OF CELL BIOLOGY
- SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination
- (2014) Jinhua Han et al. JOURNAL OF CELL BIOLOGY
- Transcriptional Repressor ZBTB1 Promotes Chromatin Remodeling and Translesion DNA Synthesis
- (2014) Hyungjin Kim et al. MOLECULAR CELL
- Modification of PCNA by ISG15 Plays a Crucial Role in Termination of Error-Prone Translesion DNA Synthesis
- (2014) Jung Mi Park et al. MOLECULAR CELL
- A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses
- (2014) Qin Liang et al. Nature Chemical Biology
- PIP degron proteins, substrates of CRL4Cdt2, and not PIP boxes, interfere with DNA polymerase η and κ focus formation on UV damage
- (2014) Nikolay Tsanov et al. NUCLEIC ACIDS RESEARCH
- USP7 modulates UV-induced PCNA monoubiquitination by regulating DNA polymerase eta stability
- (2014) J Qian et al. ONCOGENE
- Variants of mouse DNA polymerase κ reveal a mechanism of efficient and accurate translesion synthesis past a benzo[a]pyrene dG adduct
- (2014) Yang Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Pol purified with accessory subunits is active in translesion DNA synthesis and complements Pol in cisplatin bypass
- (2014) Y.-S. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNA regulation of DNA repair gene expression in 4-aminobiphenyl-treated HepG2 cells
- (2014) Lin Chen Huan et al. TOXICOLOGY
- NMR Mapping of PCNA Interaction with Translesion Synthesis DNA Polymerase Rev1 Mediated by Rev1-BRCT Domain
- (2013) Yulia Pustovalova et al. JOURNAL OF MOLECULAR BIOLOGY
- Regulation of PCNA–protein interactions for genome stability
- (2013) Niels Mailand et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability
- (2013) S. F. Mansilla et al. NUCLEIC ACIDS RESEARCH
- Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation
- (2013) Lingna Lv et al. NUCLEIC ACIDS RESEARCH
- A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks
- (2013) Michael Durando et al. NUCLEIC ACIDS RESEARCH
- BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade
- (2013) F. Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translesion DNA Synthesis and Mutagenesis in Eukaryotes
- (2013) J. E. Sale Cold Spring Harbor Perspectives in Biology
- Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells
- (2013) Jin-Gu Lee et al. Nature Communications
- Crystallization and X-ray diffraction analysis of the ternary complex of the C-terminal domain of human REV1 in complex with REV7 bound to a REV3 fragment involved in translesion DNA synthesis
- (2012) Sotaro Kikuchi et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- NMR Structure and Dynamics of the C-Terminal Domain from Human Rev1 and Its Complex with Rev1 Interacting Region of DNA Polymerase η
- (2012) Alexandra Pozhidaeva et al. BIOCHEMISTRY
- MiR-96 Downregulates REV1 and RAD51 to Promote Cellular Sensitivity to Cisplatin and PARP Inhibition
- (2012) Yemin Wang et al. CANCER RESEARCH
- Spartan/C1orf124 is important to prevent UV-induced mutagenesis
- (2012) Yuka Machida et al. CELL CYCLE
- Epidermal Growth Factor Receptor Protects Proliferating Cell Nuclear Antigen from Cullin 4A Protein-mediated Proteolysis
- (2012) Yuan-Hung Lo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) ζ, and Pol κ
- (2012) Jessica Wojtaszek et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multifaceted Recognition of Vertebrate Rev1 by Translesion Polymerases ζ and κ
- (2012) Jessica Wojtaszek et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proliferating Cell Nuclear Antigen (PCNA)-binding Protein C1orf124 Is a Regulator of Translesion Synthesis
- (2012) Gargi Ghosal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA Polymerase δ and ζ Switch by Sharing Accessory Subunits of DNA Polymerase δ
- (2012) Andrey G. Baranovskiy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- c-Jun N-terminal kinase–mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks
- (2012) Laura R. Barkley et al. MOLECULAR BIOLOGY OF THE CELL
- Spartan/C1orf124, a Reader of PCNA Ubiquitylation and a Regulator of UV-Induced DNA Damage Response
- (2012) Richard C. Centore et al. MOLECULAR CELL
- Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
- (2012) Lou K. Povlsen et al. NATURE CELL BIOLOGY
- Y-family DNA polymerases and their role in tolerance of cellular DNA damage
- (2012) Julian E. Sale et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage
- (2012) Emily J Davis et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- DVC1 (C1orf124) is a DNA damage–targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks
- (2012) Anna Mosbech et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Regulation of Rev1 by the Fanconi anemia core complex
- (2012) Hyungjin Kim et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Regulation of error-prone translesion synthesis by Spartan/C1orf124
- (2012) Myoung Shin Kim et al. NUCLEIC ACIDS RESEARCH
- Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance
- (2012) Szilvia Juhasz et al. NUCLEIC ACIDS RESEARCH
- Ubiquitin mediates the physical and functional interaction between human DNA polymerases η and ι
- (2012) Justyna McIntyre et al. NUCLEIC ACIDS RESEARCH
- A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis
- (2012) Alena V. Makarova et al. NUCLEIC ACIDS RESEARCH
- Structural basis of human DNA polymerase -mediated chemoresistance to cisplatin
- (2012) Y. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pol31 and Pol32 subunits of yeast DNA polymerase are also essential subunits of DNA polymerase
- (2012) R. E. Johnson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deubiquitinases as a Signaling Target of Oxidative Stress
- (2012) Xiomaris M. Cotto-Rios et al. Cell Reports
- Structural insights into the assembly of human translesion polymerase complexes
- (2012) Wei Xie et al. Protein & Cell
- ATR signalling: more than meeting at the fork
- (2011) Edward A. Nam et al. BIOCHEMICAL JOURNAL
- X-ray structure of the complex of regulatory subunits of human DNA polymerase delta
- (2011) Andrey G. Baranovskiy et al. CELL CYCLE
- Multiple two-polymerase mechanisms in mammalian translesion DNA synthesis
- (2011) Zvi Livneh et al. CELL CYCLE
- PIDD orchestrates translesion DNA synthesis in response to UV irradiation
- (2011) E Logette et al. CELL DEATH AND DIFFERENTIATION
- Selective and Cell-Active Inhibitors of the USP1/ UAF1 Deubiquitinase Complex Reverse Cisplatin Resistance in Non-small Cell Lung Cancer Cells
- (2011) Junjun Chen et al. CHEMISTRY & BIOLOGY
- DNA polymerase eta is targeted by Mdm2 for polyubiquitination and proteasomal degradation in response to ultraviolet irradiation
- (2011) Yong-Sam Jung et al. DNA REPAIR
- ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage
- (2011) Thomas Göhler et al. JOURNAL OF CELL BIOLOGY
- Molecular Chaperone Hsp90 Regulates REV1-Mediated Mutagenesis
- (2011) F. Mayca Pozo et al. MOLECULAR AND CELLULAR BIOLOGY
- Pirh2 E3 Ubiquitin Ligase Monoubiquitinates DNA Polymerase Eta To Suppress Translesion DNA Synthesis
- (2011) Y.-S. Jung et al. MOLECULAR AND CELLULAR BIOLOGY
- The hMsh2-hMsh6 Complex Acts in Concert with Monoubiquitinated PCNA and Pol η in Response to Oxidative DNA Damage in Human Cells
- (2011) Anastasia Zlatanou et al. MOLECULAR CELL
- NBS1 Recruits RAD18 via a RAD6-like Domain and Regulates Pol η-Dependent Translesion DNA Synthesis
- (2011) Hiromi Yanagihara et al. MOLECULAR CELL
- Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes
- (2011) Daili J A Netz et al. Nature Chemical Biology
- PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells
- (2011) Ayal Hendel et al. PLoS Genetics
- PCNA is ubiquitinated by RNF8
- (2010) Sufang Zhang et al. CELL CYCLE
- Crosstalk between replicative and translesional DNA polymerases: PDIP38 interacts directly with Polη
- (2010) Agnès Tissier et al. DNA REPAIR
- PCNA-coupled p21 degradation after DNA damage: The exception that confirms the rule?
- (2010) Gastón Soria et al. DNA REPAIR
- Crystal Structure of Human REV7 in Complex with a Human REV3 Fragment and Structural Implication of the Interaction between DNA Polymerase ζ and REV1
- (2010) Kodai Hara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human ELG1 Regulates the Level of Ubiquitinated Proliferating Cell Nuclear Antigen (PCNA) through Its Interactions with PCNA and USP1
- (2010) Kyoo-young Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylated Rad18 directs DNA Polymerase η to sites of stalled replication
- (2010) Tovah A. Day et al. JOURNAL OF CELL BIOLOGY
- WRN participates in translesion synthesis pathway through interaction with NBS1
- (2010) Junya Kobayashi et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The Molecular Chaperone Hsp90 Regulates Accumulation of DNA Polymerase η at Replication Stalling Sites in UV-Irradiated Cells
- (2010) Takayuki Sekimoto et al. MOLECULAR CELL
- Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination
- (2010) Marzena Bienko et al. MOLECULAR CELL
- CRL4Cdt2 E3 Ubiquitin Ligase Monoubiquitinates PCNA to Promote Translesion DNA Synthesis
- (2010) Kenta Terai et al. MOLECULAR CELL
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Error-prone translesion synthesis mediates acquired chemoresistance
- (2010) K. Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Y-family DNA polymerases in mammalian cells
- (2009) Caixia Guo et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- Chk1 and Claspin potentiate PCNA ubiquitination
- (2008) X. H. Yang et al. GENES & DEVELOPMENT
- Human Wrnip1 Is Localized in Replication Factories in a Ubiquitin-binding Zinc Finger-dependent Manner
- (2008) Nicola Crosetto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation
- (2008) G. Soria et al. JOURNAL OF CELL SCIENCE
- Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A
- (2008) Adelina A. Davies et al. MOLECULAR CELL
- Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination
- (2008) I. Unk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks
- (2008) A. Motegi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells
- (2008) A. Niimi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human DNA polymerase activity and translocation is regulated by phosphorylation
- (2008) Y.-w. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started