A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks

Spartan/C1orf124 is important to prevent UV-induced mutagenesis

(2012) Yuka Machida et al.   CELL CYCLE

Stalled Polη at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV1

(2012) Wakana Ito et al.   GENES TO CELLS

c-Jun N-terminal kinase–mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks

(2012) Laura R. Barkley et al.   MOLECULAR BIOLOGY OF THE CELL

Spartan/C1orf124, a Reader of PCNA Ubiquitylation and a Regulator of UV-Induced DNA Damage Response

(2012) Richard C. Centore et al.   MOLECULAR CELL

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress

(2012) Alberto Ciccia et al.   MOLECULAR CELL

DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage

(2012) Emily J Davis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DVC1 (C1orf124) is a DNA damage–targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

(2012) Anna Mosbech et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance

(2012) Szilvia Juhasz et al.   NUCLEIC ACIDS RESEARCH

Different Sets of Translesion Synthesis DNA Polymerases Protect From Genome Instability Induced by Distinct Food-Derived Genotoxins

(2012) Piya Temviriyanukul et al.   TOXICOLOGICAL SCIENCES

Ubiquitination and deubiquitination of PCNA in response to stalling of the replication fork

(2011) Stephanie Brown et al.   CELL CYCLE

PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance

(2011) Peter H.L. Krijger et al.   DNA REPAIR

DNA polymerase eta is targeted by Mdm2 for polyubiquitination and proteasomal degradation in response to ultraviolet irradiation

(2011) Yong-Sam Jung et al.   DNA REPAIR

Pirh2 E3 Ubiquitin Ligase Monoubiquitinates DNA Polymerase Eta To Suppress Translesion DNA Synthesis

(2011) Y.-S. Jung et al.   MOLECULAR AND CELLULAR BIOLOGY

NBS1 Recruits RAD18 via a RAD6-like Domain and Regulates Pol η-Dependent Translesion DNA Synthesis

(2011) Hiromi Yanagihara et al.   MOLECULAR CELL

SHPRH and HLTF Act in a Damage-Specific Manner to Coordinate Different Forms of Postreplication Repair and Prevent Mutagenesis

(2011) Jia-Ren Lin et al.   MOLECULAR CELL

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells

(2011) Ayal Hendel et al.   PLoS Genetics

Cooperation of replication Protein A with the ubiquitin ligase Rad18 in DNA damage bypass

(2010) Diana Huttner et al.   CELL CYCLE

RAD18-dependent Recruitment of SNM1A to DNA Repair Complexes by a Ubiquitin-binding Zinc Finger

(2010) Kailin Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network

(2010) Liyi Geng et al.   JOURNAL OF CELL BIOLOGY

Phosphorylated Rad18 directs DNA Polymerase η to sites of stalled replication

(2010) Tovah A. Day et al.   JOURNAL OF CELL BIOLOGY

Structure and mechanism of human DNA polymerase η

(2010) Christian Biertümpfel et al.   NATURE

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange

(2010) Bret D Freudenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen

(2009) Asami Hishiki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pirh2 E3 Ubiquitin Ligase Targets DNA Polymerase Eta for 20S Proteasomal Degradation

(2009) Y.-S. Jung et al.   MOLECULAR AND CELLULAR BIOLOGY

Chk1 and Claspin potentiate PCNA ubiquitination

(2008) X. H. Yang et al.   GENES & DEVELOPMENT

DNA Damage-induced Ubiquitylation of RFC2 Subunit of Replication Factor C Complex

(2008) Junya Tomida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Proliferating Cell Nuclear Antigen Ubiquitination and Chromatin Structure on the Dynamic Properties of the Y-family DNA Polymerases

(2008) Simone Sabbioneda et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A

(2008) Adelina A. Davies et al.   MOLECULAR CELL

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

(2008) A. Niimi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA