Structural basis of human DNA polymerase  -mediated chemoresistance to cisplatin

Multiple two-polymerase mechanisms in mammalian translesion DNA synthesis

(2011) Zvi Livneh et al.   CELL CYCLE

The status of platinum anticancer drugs in the clinic and in clinical trials

(2010) Nial J. Wheate et al.   DALTON TRANSACTIONS

Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4

(2010) Jimson HY Wong et al.   EMBO JOURNAL

Structure of duplex DNA containing the cisplatin 1,2-{Pt(NH3)2}2+-d(GpG) cross-link at 1.77Å resolution

(2010) Ryan C. Todd et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

DNA polymeraseη protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy

(2010) Kai-yuan Teng et al.   Journal of Translational Medicine

Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs

(2010) S. B. Howell et al.   MOLECULAR PHARMACOLOGY

Structural basis for the suppression of skin cancers by DNA polymerase η

(2010) Timothy D. Silverstein et al.   NATURE

Structure and mechanism of human DNA polymerase η

(2010) Christian Biertümpfel et al.   NATURE

Error-prone translesion synthesis mediates acquired chemoresistance

(2010) K. Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simultaneous Disruption of Two DNA Polymerases, Polη and Polζ, in Avian DT40 Cells Unmasks the Role of Polη in Cellular Response to Various DNA Lesions

(2010) Kouji Hirota et al.   PLoS Genetics

Structural Insight into Translesion Synthesis by DNA Pol II

(2009) Feng Wang et al.   CELL

Polymerase   mRNA Expression Predicts Survival of Non-Small Cell Lung Cancer Patients Treated with Platinum-Based Chemotherapy

(2009) P. Ceppi et al.   CLINICAL CANCER RESEARCH

Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase ι

(2009) Kevin N Kirouac et al.   EMBO JOURNAL

Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals

(2009) Sigal Shachar et al.   EMBO JOURNAL

Structural Insights into the Generation of Single-Base Deletions by the Y Family DNA Polymerase Dbh

(2008) Ryan C. Wilson et al.   MOLECULAR CELL

Transcription-coupled DNA repair: two decades of progress and surprises

(2008) Philip C. Hanawalt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase

(2008) Jessica A. Brown et al.   NUCLEIC ACIDS RESEARCH