Autophagy and microbial pathogenesis

The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

(2019) Sydney Lavoie et al.   eLife

Human cytomegalovirus hijacks the autophagic machinery and LC3 homologs in order to optimize cytoplasmic envelopment of mature infectious particles

(2019) Clémence Taisne et al.   Scientific Reports

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

(2019) Joep Grootjans et al.   SCIENCE

Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing

(2019) Yifan Zhang et al.   NATURE IMMUNOLOGY

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

(2019) Xiang Gui et al.   NATURE

Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis

(2019) Karolina Slowicka et al.   Nature Communications

A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy

(2019) Yue Xu et al.   CELL

Autophagy-Independent Functions of the Autophagy Machinery

(2019) Lorenzo Galluzzi et al.   CELL

Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins

(2019) Junghyun Lim et al.   eLife

Toll‐like receptor signalling cross‐activates the autophagic pathway to restrict Salmonella Typhimurium growth in macrophages

(2019) Wei Liu et al.   CELLULAR MICROBIOLOGY

Autophagy-virus interplay in plants: from antiviral recognition to proviral manipulation

(2019) Nirbhay Kumar Kushwaha et al.   MOLECULAR PLANT PATHOLOGY

Autophagy and Inflammation

(2018) Yu Matsuzawa-Ishimoto et al.   Annual Review of Immunology

Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria

(2018) Matthew T. Sorbara et al.   Cell Host & Microbe

Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii -Mediated Inflammation

(2018) Elise Burger et al.   Cell Host & Microbe

Inflammation-Induced, STING-Dependent Autophagy Restricts Zika Virus Infection in the Drosophila Brain

(2018) Yuan Liu et al.   Cell Host & Microbe

Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice

(2018) Johanna Pott et al.   Cell Host & Microbe

Knockout of autophagy gene, ATG5 in mice vaginal cells abrogates cytokine response and pathogen clearance during vaginal infection of Candida albicans

(2018) Ankit Shroff et al.   CELLULAR IMMUNOLOGY

The WD40 domain of ATG16L1 is required for its non‐canonical role in lipidation of LC3 at single membranes

(2018) Katherine Fletcher et al.   EMBO JOURNAL

Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling

(2018) Mohammad Samie et al.   NATURE IMMUNOLOGY

Enteroviral Infection Inhibits Autophagic Flux via Disruption of the SNARE Complex to Enhance Viral Replication

(2018) Yasir Mohamud et al.   Cell Reports

Enteroviruses Remodel Autophagic Trafficking through Regulation of Host SNARE Proteins to Promote Virus Replication and Cell Exit

(2018) Abigail K. Corona et al.   Cell Reports

Calcium sequestration by fungal melanin inhibits calcium–calmodulin signalling to prevent LC3-associated phagocytosis

(2018) Irene Kyrmizi et al.   Nature Microbiology

Impaired Autophagy in Intestinal Epithelial Cells Alters Gut Microbiota and Host Immune Responses

(2018) Lingyu Yang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING

(2018) Konrad Aden et al.   JOURNAL OF EXPERIMENTAL MEDICINE

There was collusion: Microbes in inflammatory bowel disease

(2018) Serre-Yu Wong et al.   PLoS Pathogens

Autophagy proteins suppress protective type I interferon signalling in response to the murine gut microbiota

(2018) Patricia K. Martin et al.   Nature Microbiology

An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread

(2018) Joel M. J. Tan et al.   Nature Microbiology

Beyond self-eating: The control of nonautophagic functions and signaling pathways by autophagy-related proteins

(2017) Ken Cadwell et al.   JOURNAL OF CELL BIOLOGY

Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis

(2017) Markus Tschurtschenthaler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IKKα controls ATG16L1 degradation to prevent ER stress during inflammation

(2017) Michaela A. Diamanti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice

(2017) Bin Cao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

(2017) Yu Matsuzawa-Ishimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Myeloid ATG16L1 Facilitates Host–Bacteria Interactions in Maintaining Intestinal Homeostasis

(2017) Hong Zhang et al.   JOURNAL OF IMMUNOLOGY

The Inflammatory Bowel Disease–Associated Autophagy GeneAtg16L1T300AActs as a Dominant Negative Variant in Mice

(2017) Ping Gao et al.   JOURNAL OF IMMUNOLOGY

PLA2G16 represents a switch between entry and clearance of Picornaviridae

(2017) Jacqueline Staring et al.   NATURE

Listeria monocytogenestriggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy

(2017) Gabriel Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine

(2017) Shai Bel et al.   SCIENCE

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

(2017) W. K. Eddie Ip et al.   SCIENCE

Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy

(2017) Jose-Andres C. Portillo et al.   PLoS Pathogens

Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes

(2017) Eliana Real et al.   Nature Microbiology

Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation

(2017) Sjoerd J. L. van Wijk et al.   Nature Microbiology

LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB

(2017) Jessica Noad et al.   Nature Microbiology

Targeting by AutophaGy proteins (TAG): Targeting of IFNG-inducible GTPases to membranes by the LC3 conjugation system of autophagy

(2016) Sungwoo Park et al.   Autophagy

Fanconi Anemia Proteins Function in Mitophagy and Immunity

(2016) Rhea Sumpter et al.   CELL

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

(2016) Zhenyu Zhong et al.   CELL

Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity

(2016) Tonia Akoumianaki et al.   Cell Host & Microbe

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis

(2016) Qun Lu et al.   Cell Host & Microbe

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation

(2016) Sunmin Park et al.   Cell Host & Microbe

Noncanonical Fungal Autophagy Inhibits Inflammation in Response to IFN-γ via DAPK1

(2016) Vasilis Oikonomou et al.   Cell Host & Microbe

Intrinsic Defense Mechanisms of the Intestinal Epithelium

(2016) Deepshika Ramanan et al.   Cell Host & Microbe

Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy

(2016) Tomonori Kimura et al.   EMBO JOURNAL

Exocytosis of Varicella-Zoster Virus Virions Involves a Convergence of Endosomal and Autophagy Pathways

(2016) Erin M. Buckingham et al.   JOURNAL OF VIROLOGY

Global Analysis of Host and Bacterial Ubiquitinome in Response to Salmonella Typhimurium Infection

(2016) Evgenij Fiskin et al.   MOLECULAR CELL

LAP-like process as an immune mechanism downstream of IFN-γ in control of the human malariaPlasmodium vivaxliver stage

(2016) Rachasak Boonhok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ATG conjugation systems are important for degradation of the inner autophagosomal membrane

(2016) Kotaro Tsuboyama et al.   SCIENCE

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease

(2016) H. Chu et al.   SCIENCE

TLR-7 activation enhances IL-22–mediated colonization resistance against vancomycin-resistant enterococcus

(2016) Michael C. Abt et al.   Science Translational Medicine

The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1

(2016) Emilio Boada-Romero et al.   Nature Communications

RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy

(2016) Robert J. Heath et al.   Cell Reports

Autophagy is a key tolerance mechanism during Staphylococcus aureus infection

(2015) Katie Maurer et al.   Autophagy

Phosphatidylserine Vesicles Enable Efficient En Bloc Transmission of Enteroviruses

(2015) Ying-Han Chen et al.   CELL

Autophagy Mediates Tolerance to Staphylococcus aureus Alpha-Toxin

(2015) Katie Maurer et al.   Cell Host & Microbe

Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation

(2015) Xiaorong Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

IRGM Governs the Core Autophagy Machinery to Conduct Antimicrobial Defense

(2015) Santosh Chauhan et al.   MOLECULAR CELL

ATG16L1 deficiency in macrophages drives clearance of uropathogenic E. coli in an IL-1β-dependent manner

(2015) J W Symington et al.   Mucosal Immunology

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

(2015) Jacqueline M. Kimmey et al.   NATURE

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

(2015) Elizabeth M. Selleck et al.   mBio

Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

(2015) Min Zhang et al.   eLife

The Immune Receptor NOD1 and Kinase RIP2 Interact with Bacterial Peptidoglycan on Early Endosomes to Promote Autophagy and Inflammatory Signaling

(2014) Aaron T. Irving et al.   Cell Host & Microbe

A LC3-Interacting Motif in the Influenza A Virus M2 Protein Is Required to Subvert Autophagy and Maintain Virion Stability

(2014) Rupert Beale et al.   Cell Host & Microbe

Inflammatory Bowel Disease as a Model for Translating the Microbiome

(2014) Curtis Huttenhower et al.   IMMUNITY

Antiviral Autophagy Restricts Rift Valley Fever Virus Infection and Is Conserved from Flies to Mammals

(2014) Ryan H. Moy et al.   IMMUNITY

The Parasitophorous Vacuole Membrane of Toxoplasma gondii Is Targeted for Disruption by Ubiquitin-like Conjugation Systems of Autophagy

(2014) Jayoung Choi et al.   IMMUNITY

Innate Host Defense Requires TFEB-Mediated Transcription of Cytoprotective and Antimicrobial Genes

(2014) Orane Visvikis et al.   IMMUNITY

Role of Mouse and Human Autophagy Proteins in IFN- -Induced Cell-Autonomous Responses against Toxoplasma gondii

(2014) J. Ohshima et al.   JOURNAL OF IMMUNOLOGY

Dectin-1–Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages

(2014) Jenny M. Tam et al.   JOURNAL OF INFECTIOUS DISEASES

Functional Role of Autophagy-Mediated Proteome Remodeling in Cell Survival Signaling and Innate Immunity

(2014) Robin Mathew et al.   MOLECULAR CELL

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1

(2014) Hannah C. Dooley et al.   MOLECULAR CELL

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

(2014) Aditya Murthy et al.   NATURE

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

(2014) Etienne Meunier et al.   NATURE

An enteric virus can replace the beneficial function of commensal bacteria

(2014) Elisabeth Kernbauer et al.   NATURE

Autophagy is essential for effector CD8+ T cell survival and memory formation

(2014) Xiaojin Xu et al.   NATURE IMMUNOLOGY

The E2-Like Conjugation Enzyme Atg3 Promotes Binding of IRG and Gbp Proteins to Chlamydia- and Toxoplasma-Containing Vacuoles and Host Resistance

(2014) Arun K. Haldar et al.   PLoS One

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

(2014) K. G. Lassen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonlytic viral spread enhanced by autophagy components

(2014) S. W. Bird et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

(2014) Antonella de Luca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy is a critical regulator of memory CD8+ T cell formation

(2014) Daniel J Puleston et al.   eLife

Macroautophagy Proteins Assist Epstein Barr Virus Production and Get Incorporated Into the Virus Particles

(2014) Heike Nowag et al.   EBioMedicine

ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis

(2013) Sandra Cabrera et al.   Autophagy

Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signaling

(2013) Junyan Shi et al.   Autophagy

Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling

(2013) Hiroyasu Konno et al.   CELL

A Deficiency in the Autophagy Gene Atg16L1 Enhances Resistance to Enteric Bacterial Infection

(2013) Amanda M. Marchiando et al.   Cell Host & Microbe

Intestinal Epithelial Autophagy Is Essential for Host Defense against Invasive Bacteria

(2013) Jamaal L. Benjamin et al.   Cell Host & Microbe

The Globally Disseminated M1T1 Clone of Group A Streptococcus Evades Autophagy for Intracellular Replication

(2013) Timothy C. Barnett et al.   Cell Host & Microbe

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

(2013) Khushbu K Patel et al.   EMBO JOURNAL

FIP200 regulates targeting of Atg16L1 to the isolation membrane

(2013) Taki Nishimura et al.   EMBO REPORTS

Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice From Salmonella Infection

(2013) Kara L. Conway et al.   GASTROENTEROLOGY

Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohn's disease

(2013) J Jasper Deuring et al.   GUT

Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing

(2013) Susana Romao et al.   JOURNAL OF CELL BIOLOGY

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

(2013) Paolo S. Manzanillo et al.   NATURE

Autophagosomes form at ER–mitochondria contact sites

(2013) Maho Hamasaki et al.   NATURE

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

Paneth cells as a site of origin for intestinal inflammation

(2013) Timon E. Adolph et al.   NATURE

Receptor interacting protein kinase 2–mediated mitophagy regulates inflammasome activation during virus infection

(2013) Christopher Lupfer et al.   NATURE IMMUNOLOGY

Vaccine Activation of the Nutrient Sensor GCN2 in Dendritic Cells Enhances Antigen Presentation

(2013) R. Ravindran et al.   SCIENCE

COX5B Regulates MAVS-mediated Antiviral Signaling through Interaction with ATG5 and Repressing ROS Production

(2013) Yuanyuan Zhao et al.   PLoS Pathogens

The Zebrafish as a New Model for the In Vivo Study of Shigella flexneri Interaction with Phagocytes and Bacterial Autophagy

(2013) Serge Mostowy et al.   PLoS Pathogens

Toxoplasma gondii-Induced Activation of EGFR Prevents Autophagy Protein-Mediated Killing of the Parasite

(2013) Luis Muniz-Feliciano et al.   PLoS Pathogens

The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

(2013) Liang Ge et al.   eLife

Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

(2012) Seungmin Hwang et al.   Cell Host & Microbe

Pancreatic Acinar Cell-Specific Autophagy Disruption Reduces Coxsackievirus Replication and Pathogenesis In Vivo

(2012) Mehrdad Alirezaei et al.   Cell Host & Microbe

A Neuron-Specific Role for Autophagy in Antiviral Defense against Herpes Simplex Virus

(2012) Brian Yordy et al.   Cell Host & Microbe

The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin-Dependent Autophagy of Intracellular Salmonella Typhimurium

(2012) Alan Huett et al.   Cell Host & Microbe

Selective Subversion of Autophagy Complexes Facilitates Completion of the Brucella Intracellular Cycle

(2012) Tregei Starr et al.   Cell Host & Microbe

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

(2012) Yu Lei et al.   IMMUNITY

Macrophage Autophagy in Immunity to Cryptococcus neoformans and Candida albicans

(2012) André Moraes Nicola et al.   INFECTION AND IMMUNITY

A Dual Role for Receptor-interacting Protein Kinase 2 (RIP2) Kinase Activity in Nucleotide-binding Oligomerization Domain 2 (NOD2)-dependent Autophagy

(2012) Craig R. Homer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Atg16L1 deficiency confers protection from uropathogenic Escherichia coli infection in vivo

(2012) C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

(2012) A. Choy et al.   SCIENCE

Human Rhinovirus 2 Induces the Autophagic Pathway and Replicates More Efficiently in Autophagic Cells

(2011) K. A. Klein et al.   JOURNAL OF VIROLOGY

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network

(2011) Isabel Pombo Grégoire et al.   PLoS Pathogens

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Entrapment of Intracytosolic Bacteria by Septin Cage-like Structures

(2010) Serge Mostowy et al.   Cell Host & Microbe

Autophagy Protects against Sindbis Virus Infection of the Central Nervous System

(2010) Anthony Orvedahl et al.   Cell Host & Microbe

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

Listeriolysin O Is Necessary and Sufficient to Induce Autophagy during Listeria monocytogenes Infection

(2010) Nicole Meyer-Morse et al.   PLoS One

A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn disease

(2009) Ken Cadwell et al.   Autophagy

The autophagic pathway is a key component in the lysosomal dependent entry ofTrypanosoma cruziinto the host cell

(2009) Patricia S. Romano et al.   Autophagy

Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes

(2009) Monique Gannagé et al.   Cell Host & Microbe

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

Interaction of ICP34.5 with Beclin 1 Modulates Herpes Simplex Virus Type 1 Pathogenesis through Control of CD4+ T-Cell Responses

(2009) D. A. Leib et al.   JOURNAL OF VIROLOGY

Listeria monocytogenes ActA-mediated escape from autophagic recognition

(2009) Yuko Yoshikawa et al.   NATURE CELL BIOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

(2009) K. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

(2009) T. Saitoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling

(2009) Michal Caspi Tal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral Bcl-2-Mediated Evasion of Autophagy Aids Chronic Infection of γHerpesvirus 68

(2009) Xiaofei E et al.   PLoS Pathogens

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

Autophagosome Supports Coxsackievirus B3 Replication in Host Cells

(2008) J. Wong et al.   JOURNAL OF VIROLOGY

Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles

(2008) Cheryl L. Birmingham et al.   NATURE

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Autophagic control of listeria through intracellular innate immune recognition in drosophila

(2008) Tamaki Yano et al.   NATURE IMMUNOLOGY