An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread

Listeriolysin O: from bazooka to Swiss army knife

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Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack

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Mammalian autophagy and the plasma membrane

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A functional ATG16L1 (T300A) variant is associated with necrotizing enterocolitis in premature infants

(2016) Venkatesh Sampath et al.   PEDIATRIC RESEARCH

Digesting the Expanding Mechanisms of Autophagy

(2016) Nicholas T. Ktistakis et al.   TRENDS IN CELL BIOLOGY

Plasma membrane and cytoskeleton dynamics during single-cell wound healing

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Ca2+-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins

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Autophagy Mediates Tolerance to Staphylococcus aureus Alpha-Toxin

(2015) Katie Maurer et al.   Cell Host & Microbe

Lysosomal proteins in cell death and autophagy

(2015) Michaela Mrschtik et al.   FEBS Journal

Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol

(2015) M. Maekawa et al.   JOURNAL OF CELL SCIENCE

ATG12–ATG3 interacts with Alix to promote basal autophagic flux and late endosome function

(2015) Lyndsay Murrow et al.   NATURE CELL BIOLOGY

Pore-forming toxins: ancient, but never really out of fashion

(2015) Matteo Dal Peraro et al.   NATURE REVIEWS MICROBIOLOGY

ATG16L1 T300A Polymorphism is Correlated with Gastric Cancer Susceptibility

(2015) Florin Burada et al.   PATHOLOGY & ONCOLOGY RESEARCH

The autophagic machinery ensures nonlytic transmission of mycobacteria

(2015) Lilli Gerstenmaier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defying death: Cellular survival strategies following plasmalemmal injury by bacterial toxins

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Organelle targeting during bacterial infection: insights from Listeria

(2015) Alice Lebreton et al.   TRENDS IN CELL BIOLOGY

Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection

(2015) Feiran Lu et al.   eLife

Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread

(2014) Mark A. Czuczman et al.   NATURE

ESCRT Machinery Is Required for Plasma Membrane Repair

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Damage control: cellular mechanisms of plasma membrane repair

(2014) Norma W. Andrews et al.   TRENDS IN CELL BIOLOGY

Diverse Autophagosome Membrane Sources Coalesce in Recycling Endosomes

(2013) Claudia Puri et al.   CELL

A Deficiency in the Autophagy Gene Atg16L1 Enhances Resistance to Enteric Bacterial Infection

(2013) Amanda M. Marchiando et al.   Cell Host & Microbe

Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice From Salmonella Infection

(2013) Kara L. Conway et al.   GASTROENTEROLOGY

Stiffened lipid platforms at molecular force foci

(2013) A. Anishkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

More Than a Pore: The Cellular Response to Cholesterol-Dependent Cytolysins

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Vacuolating Cytotoxin and Variants in Atg16L1 That Disrupt Autophagy Promote Helicobacter pylori Infection in Humans

(2012) Deepa Raju et al.   GASTROENTEROLOGY

Mechanism of polarized lysosome exocytosis in epithelial cells

(2012) J. Xu et al.   JOURNAL OF CELL SCIENCE

Membrane Damage during Listeria monocytogenes Infection Triggers a Caspase-7 Dependent Cytoprotective Response

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Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

(2011) Mireille Ouimet et al.   Cell Metabolism

Pore-forming toxins induce multiple cellular responses promoting survival

(2011) Manuel R. Gonzalez et al.   CELLULAR MICROBIOLOGY

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Blebbing confers resistance against cell lysis

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Listeriolysin O Is Necessary and Sufficient to Induce Autophagy during Listeria monocytogenes Infection

(2010) Nicole Meyer-Morse et al.   PLoS One

The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease

(2009) Bengt Fadeel et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Differential Involvement of Atg16L1 in Crohn Disease and Canonical Autophagy

(2009) Naonobu Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lifeact cannot visualize some forms of stress-induced twisted f-actin

(2009) Lise N Munsie et al.   NATURE METHODS

Role of cortical tension in bleb growth

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Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

Functional and Phylogenetic Characterization of Vaginolysin, the Human-Specific Cytolysin from Gardnerella vaginalis

(2008) S. E. Gelber et al.   JOURNAL OF BACTERIOLOGY

Cholesterol Accumulation by Macrophages Impairs Phagosome Maturation

(2008) Kassidy K. Huynh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The LXR agonist T0901317 promotes the reverse cholesterol transport from macrophages by increasing plasma efflux potential

(2008) Ilaria Zanotti et al.   JOURNAL OF LIPID RESEARCH

Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles

(2008) Cheryl L. Birmingham et al.   NATURE

Cellular cholesterol trafficking and compartmentalization

(2008) Elina Ikonen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant

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