Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

Mouse Genome Engineering via CRISPR-Cas9 for Study of Immune Function

(2015) Stephane Pelletier et al.   IMMUNITY

The Parasitophorous Vacuole Membrane of Toxoplasma gondii Is Targeted for Disruption by Ubiquitin-like Conjugation Systems of Autophagy

(2014) Jayoung Choi et al.   IMMUNITY

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

(2014) Aditya Murthy et al.   NATURE

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans

(2014) Antonella de Luca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential role for UVRAG in autophagy and maintenance of cardiac function

(2013) Zongpei Song et al.   CARDIOVASCULAR RESEARCH

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

(2013) F. Ann Ran et al.   CELL

Noncanonical Autophagy Promotes the Visual Cycle

(2013) Ji-Young Kim et al.   CELL

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

The Autophagy Regulator Rubicon Is a Feedback Inhibitor of CARD9-Mediated Host Innate Immunity

(2012) Chul-Su Yang et al.   Cell Host & Microbe

Autophagy Protein Rubicon Mediates Phagocytic NADPH Oxidase Activation in Response to Microbial Infection or TLR Stimulation

(2012) Chul-Su Yang et al.   Cell Host & Microbe

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis

(2012) T. Willinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

(2012) A. Choy et al.   SCIENCE

Autophagy and cytokines

(2011) James Harris   CYTOKINE

Cooperation of p40phoxwith p47phoxfor Nox2-based NADPH Oxidase Activation during Fcγ Receptor (FcγR)-mediated Phagocytosis

(2011) Takehiko Ueyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy: cellular defense to excessive inflammation

(2011) Eun-Kyeong Jo et al.   MICROBES AND INFECTION

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

(2011) Oliver Florey et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

(2010) Hannah E.J. Polson et al.   Autophagy

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Role of autophagy in suppression of inflammation and cancer

(2010) Eileen White et al.   CURRENT OPINION IN CELL BIOLOGY

Regulation of NADPH Oxidase Activity in Phagocytes

(2010) Franck Debeurme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RUN Domain of Rubicon Is Important for hVps34 Binding, Lipid Kinase Inhibition, and Autophagy Suppression

(2010) Qiming Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rubicon controls endosome maturation as a Rab7 effector

(2010) Q. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation and Biological Activities of Oxidized Phospholipids

(2009) Valery N. Bochkov et al.   ANTIOXIDANTS & REDOX SIGNALING

Systematical Optimization of Reverse-Phase Chromatography for Shotgun Proteomics

(2009) Ping Xu et al.   JOURNAL OF PROTEOME RESEARCH

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

(2009) Yun Zhong et al.   NATURE CELL BIOLOGY

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Activation of antibacterial autophagy by NADPH oxidases

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

Oxidized Lipids Formed Non-enzymatically by Reactive Oxygen Species

(2008) William L. Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL