Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

NADPH Oxidase NOX2 Defines a New Antagonistic Role for Reactive Oxygen Species and cAMP/PKA in the Regulation of Insulin Secretion

(2012) N. Li et al.   DIABETES

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Endotoxin Priming of Neutrophils Requires Endocytosis and NADPH Oxidase-dependent Endosomal Reactive Oxygen Species

(2012) Fred S. Lamb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes

(2012) Andrea Longatti et al.   JOURNAL OF CELL BIOLOGY

Wnt5a Potentiates TGF-  Signaling to Promote Colonic Crypt Regeneration After Tissue Injury

(2012) H. Miyoshi et al.   SCIENCE

Listeriolysin O Suppresses Phospholipase C-Mediated Activation of the Microbicidal NADPH Oxidase to Promote Listeria monocytogenes Infection

(2011) Grace Y. Lam et al.   Cell Host & Microbe

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

Dll1- and Dll4-Mediated Notch Signaling Are Required for Homeostasis of Intestinal Stem Cells

(2011) Luca Pellegrinet et al.   GASTROENTEROLOGY

Crucial role for autophagy in degranulation of mast cells

(2011) Hiroko Ushio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

(2011) Oliver Florey et al.   NATURE CELL BIOLOGY

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Mucin dynamics and enteric pathogens

(2011) Michael A. McGuckin et al.   NATURE REVIEWS MICROBIOLOGY

Does NAD(P)H oxidase-derived H2O2 participate in hypotonicity-induced insulin release by activating VRAC in β-cells?

(2011) R. Crutzen et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

(2011) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

(2010) M. Morimoto et al.   JOURNAL OF CELL SCIENCE

Autophagy is essential for mouse sense of balance

(2010) Guillermo Mariño et al.   JOURNAL OF CLINICAL INVESTIGATION

Plasma membrane contributes to the formation of pre-autophagosomal structures

(2010) Brinda Ravikumar et al.   NATURE CELL BIOLOGY

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

(2010) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The many roles of NOX2 NADPH oxidase-derived ROS in immunity

(2010) Grace Y. Lam et al.   Seminars in Immunopathology

A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn disease

(2009) Ken Cadwell et al.   Autophagy

Early endosomes and endosomal coatomer are required for autophagy

(2009) Minoo Razi et al.   JOURNAL OF CELL BIOLOGY

Macrophage NADPH Oxidase Flavocytochrome b Localizes to the Plasma Membrane and Rab11-Positive Recycling Endosomes

(2009) A.-J. Casbon et al.   JOURNAL OF IMMUNOLOGY

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Activation of antibacterial autophagy by NADPH oxidases

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of Protein Transduction Domains in Mediating Cell Delivery of a Secreted CRE Protein†

(2008) Paul A. Shaw et al.   BIOCHEMISTRY

Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia

(2008) Hye Seung Jung et al.   Cell Metabolism

Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet

(2008) Chie Ebato et al.   Cell Metabolism

Munc13-2−/−baseline secretion defect reveals source of oligomeric mucins in mouse airways

(2008) Yunxiang Zhu et al.   JOURNAL OF PHYSIOLOGY-LONDON

The intestinal epithelium: sensors to effectors in nematode infection

(2008) D Artis et al.   Mucosal Immunology

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Regulated Airway Goblet Cell Mucin Secretion

(2007) C. William Davis et al.   Annual Review of Physiology