The Role of Lysyl Oxidase Enzymes in Cardiac Function and Remodeling
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Role of Lysyl Oxidase Enzymes in Cardiac Function and Remodeling
Authors
Keywords
-
Journal
Cells
Volume 8, Issue 12, Pages 1483
Publisher
MDPI AG
Online
2019-11-22
DOI
10.3390/cells8121483
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mechanical regulation of gene expression in cardiac myocytes and fibroblasts
- (2019) Jeffrey J. Saucerman et al. Nature Reviews Cardiology
- Myofibroblast Phenotype and Reversibility of Fibrosis in Patients With End-Stage Heart Failure
- (2019) Chandan K. Nagaraju et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Induction of LOX by TGF‐β1/Smad/AP‐1 signaling aggravates rat myocardial fibrosis and heart failure
- (2019) Min Lu et al. IUBMB LIFE
- NOTCH activation promotes valve formation by regulating the endocardial secretome
- (2019) Rebeca Torregrosa-Carrión et al. MOLECULAR & CELLULAR PROTEOMICS
- Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues
- (2019) Gabriela Leão Santos et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The non-steroidal mineralocorticoid receptor antagonist finerenone prevents cardiac fibrotic remodeling
- (2019) Daniel Lavall et al. BIOCHEMICAL PHARMACOLOGY
- Severe Cardiac Dysfunction and Death Caused by Arrhythmogenic Right Ventricular Cardiomyopathy Type 5 Are Improved by Inhibition of Glycogen Synthase Kinase-3β
- (2019) Laura Padrón-Barthe et al. CIRCULATION
- Emerging Roles of Lysyl Oxidases in the Cardiovascular System: New Concepts and Therapeutic Challenges
- (2019) Martínez-González et al. Biomolecules
- Inhibitor of lysyl oxidase improves cardiac function and the collagen/MMP profile in response to volume overload
- (2018) Elia C El Hajj et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Inhibition of enzymes involved in collagen cross-linking reduces vascular smooth muscle cell calcification
- (2018) Eva Jover et al. FASEB JOURNAL
- LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy
- (2018) Leonie Rossow et al. ONCOGENE
- Crystal structure of human lysyl oxidase-like 2 (hLOXL2) in a precursor state
- (2018) Xi Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Is This the Last Requiem for Simtuzumab?
- (2018) Peter Fickert HEPATOLOGY
- The lysyl oxidase like 2/3 enzymatic inhibitor, PXS‐5153A, reduces crosslinks and ameliorates fibrosis
- (2018) Heidi Schilter et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
- (2018) Nora Franceschini et al. Nature Communications
- Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II–induced hypertrophy
- (2017) María Galán et al. FASEB JOURNAL
- Transforming growth factor (TGF)-β1 signal pathway: A promising therapeutic target for attenuating cardiac fibrosis
- (2017) Jin Xie et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2)
- (2017) Martin W. Rowbottom et al. JOURNAL OF MEDICINAL CHEMISTRY
- Detrimental role of lysyl oxidase in cardiac remodeling
- (2017) Elia C. El Hajj et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- MicroRNA-19b is a potential biomarker of increased myocardial collagen cross-linking in patients with aortic stenosis and heart failure
- (2017) Javier Beaumont et al. Scientific Reports
- Effects of 6-months' Exercise on Cardiac Function, Structure and Metabolism in Female Hypertensive Rats–The Decisive Role of Lysyl Oxidase and Collagen III
- (2017) Rolf Schreckenberg et al. Frontiers in Physiology
- Functional importance of lysyl oxidase family propeptide regions
- (2017) Philip C. Trackman Journal of Cell Communication and Signaling
- Transgenic mice overexpressing desmocollin-2 (DSC2) develop cardiomyopathy associated with myocardial inflammation and fibrotic remodeling
- (2017) Andreas Brodehl et al. PLoS One
- Mechanisms underlying the cardiac antifibrotic effects of losartan metabolites
- (2017) José Luis Miguel-Carrasco et al. Scientific Reports
- Lysyl oxidase expression in cardiac fibroblasts is regulated by α2β1 integrin interactions with the cellular microenvironment
- (2016) Albert E. Gao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome
- (2016) Shiwani Sharma et al. EXPERIMENTAL EYE RESEARCH
- Cross-linking versus RAGE: How do high molecular weight advanced glycation products induce cardiac dysfunction?
- (2016) Dorien Deluyker et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase
- (2016) Sebastian Kalamajski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanical control of cardiac myofibroblasts
- (2016) Sander van Putten et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats
- (2016) Ernesto Martínez-Martínez et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- TRAF3IP2 mediates aldosterone/salt-induced cardiac hypertrophy and fibrosis
- (2016) Siva S.V.P. Sakamuri et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment
- (2016) Jin Yang et al. Nature Communications
- The role of myofibroblasts in wound healing
- (2016) B. Hinz Current Research in Translational Medicine
- Disruption of Collagen Homeostasis Can Reverse Established Age-Related Myocardial Fibrosis
- (2015) Nicole L. Rosin et al. AMERICAN JOURNAL OF PATHOLOGY
- Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart
- (2015) Kate M. Herum et al. CARDIOVASCULAR RESEARCH
- Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction
- (2015) José González-Santamaría et al. CARDIOVASCULAR RESEARCH
- Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression
- (2015) A. Martin et al. EMBO JOURNAL
- Featured Article: Cardioprotective effects of lysyl oxidase inhibition against volume overload-induced extracellular matrix remodeling
- (2015) Elia C El Hajj et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Loss of lysyl oxidase-like 3 causes cleft palate and spinal deformity in mice
- (2015) Jian Zhang et al. HUMAN MOLECULAR GENETICS
- Excess Linoleic Acid Increases Collagen I/III Ratio and “Stiffens” the Heart Muscle Following High Fat Diets
- (2015) Julianne Beam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice
- (2015) Oliver Adam et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Lysyl Oxidases Play a Causal Role in Vascular Remodeling in Clinical and Experimental Pulmonary Arterial Hypertension
- (2014) A. H. Nave et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Lysyl oxidase (LOX) in vascular remodelling: insight from a new animal model
- (2014) M. Orriols et al. ATHEROSCLEROSIS
- Exfoliation Syndrome and Systemic Cardiovascular Diseases
- (2014) Gábor Holló JOURNAL OF GLAUCOMA
- Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKα1
- (2014) Gauthier Noppe et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Expression of matrix metalloproteinases, their inhibitors, and lysyl oxidase in myocardial samples from dogs with end-stage systemic and cardiac diseases
- (2013) Sonja Fonfara et al. AMERICAN JOURNAL OF VETERINARY RESEARCH
- Osteopontin-mediated myocardial fibrosis in heart failure: a role for lysyl oxidase?
- (2013) Begoña López et al. CARDIOVASCULAR RESEARCH
- The pathogenesis of cardiac fibrosis
- (2013) Ping Kong et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats
- (2013) Germán E. González et al. CLINICAL SCIENCE
- LOXL4 Is Induced by Transforming Growth Factor 1 through Smad and JunB/Fra2 and Contributes to Vascular Matrix Remodeling
- (2013) O. Busnadiego et al. MOLECULAR AND CELLULAR BIOLOGY
- Global Gene Expression Profiling in PAI-1 Knockout Murine Heart and Kidney: Molecular Basis of Cardiac-Selective Fibrosis
- (2013) Asish K. Ghosh et al. PLoS One
- Left and Right Ventricle Late Remodeling Following Myocardial Infarction in Rats
- (2013) Ivanita Stefanon et al. PLoS One
- Role of miR-21 in the pathogenesis of atrial fibrosis
- (2012) Oliver Adam et al. BASIC RESEARCH IN CARDIOLOGY
- Immunohistochemical detection of differentially localized up-regulation of lysyl oxidase and down-regulation of matrix metalloproteinase-1 in rhesus monkey model of chronic myocardial infarction
- (2012) Yuping Xie et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Collagen Cross-Linking But Not Collagen Amount Associates With Elevated Filling Pressures in Hypertensive Patients With Stage C Heart Failure
- (2012) Begoña López et al. HYPERTENSION
- Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice
- (2012) Haruya Ohmura et al. HYPERTENSION RESEARCH
- TNF-α increases cardiac fibroblast lysyl oxidase expression through TGF-β and PI3Kinase signaling pathways
- (2011) Tetyana G. Voloshenyuk et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling
- (2011) Tetyana G. Voloshenyuk et al. CYTOKINE
- Increased lysyl oxidase expression and collagen cross-linking during atrial fibrillation
- (2011) Oliver Adam et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Diastolic Tissue Doppler Indexes Correlate With the Degree of Collagen Expression and Cross-Linking in Heart Failure and Normal Ejection Fraction
- (2011) Mario Kasner et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- The Conserved Scavenger Receptor Cysteine-Rich Superfamily in Therapy and Diagnosis
- (2011) V. G. Martinez et al. PHARMACOLOGICAL REVIEWS
- Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects
- (2010) Begoña López et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Intracellular lysyl oxidase: Effect of a specific inhibitor on nuclear mass in proliferating cells
- (2010) Fawzy A. Saad et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- T Lymphocyte Regulation of Lysyl Oxidase in Diet-Induced Cardiac Fibrosis
- (2010) Sherma Zibadi et al. Cardiovascular Toxicology
- Transforming growth factor (TGF)-β signaling in cardiac remodeling
- (2010) Marcin Dobaczewski et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- T-lymphocytes mediate left ventricular fibrillar collagen cross-linking and diastolic dysfunction in mice
- (2010) Qianli Yu et al. MATRIX BIOLOGY
- In search of a new therapeutic target for the treatment of genetically triggered thoracic aortic aneurysms and cardiovascular conditions: insights from human and animal lathyrism
- (2010) H. M. F. Sherif Interactive Cardiovascular and Thoracic Surgery
- Myocardial lysyl oxidase regulation of cardiac remodeling in a murine model of diet-induced metabolic syndrome
- (2009) Sherma Zibadi et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Lysyl oxidase as a potential therapeutic target
- (2009) C. Rodríguez et al. DRUG NEWS & PERSPECTIVES
- Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase
- (2009) Masahito Horiguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases
- (2008) C. Rodriguez et al. CARDIOVASCULAR RESEARCH
- A synthetic peptide from transforming growth factor- 1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats
- (2008) N. Hermida et al. CARDIOVASCULAR RESEARCH
- Impact of Treatment on Myocardial Lysyl Oxidase Expression and Collagen Cross-Linking in Patients With Heart Failure
- (2008) Begoña López et al. HYPERTENSION
- Dystrophin-deficient cardiomyopathy in mouse: Expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart
- (2008) Christopher F. Spurney et al. NEUROMUSCULAR DISORDERS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started