Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction

Disruption of Collagen Homeostasis Can Reverse Established Age-Related Myocardial Fibrosis

(2015) Nicole L. Rosin et al.   AMERICAN JOURNAL OF PATHOLOGY

Induction of the calcineurin variant CnAβ1 after myocardial infarction reduces post-infarction ventricular remodelling by promoting infarct vascularization

(2014) Marina M. López-Olañeta et al.   CARDIOVASCULAR RESEARCH

Developmental Heterogeneity of Cardiac Fibroblasts Does Not Predict Pathological Proliferation and Activation

(2014) Shah R. Ali et al.   CIRCULATION RESEARCH

Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis

(2014) Thomas Moore-Morris et al.   JOURNAL OF CLINICAL INVESTIGATION

Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5

(2014) Kristin V.T. Engebretsen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A Pathogenetic Role for Endothelin-1 in Peritoneal Dialysis-Associated Fibrosis

(2014) O. Busnadiego et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Osteopontin-mediated myocardial fibrosis in heart failure: a role for lysyl oxidase?

(2013) Begoña López et al.   CARDIOVASCULAR RESEARCH

The pathogenesis of cardiac fibrosis

(2013) Ping Kong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype

(2013) Chris J. Watson et al.   HUMAN MOLECULAR GENETICS

LOXL4 Is Induced by Transforming Growth Factor  1 through Smad and JunB/Fra2 and Contributes to Vascular Matrix Remodeling

(2013) O. Busnadiego et al.   MOLECULAR AND CELLULAR BIOLOGY

Left and Right Ventricle Late Remodeling Following Myocardial Infarction in Rats

(2013) Ivanita Stefanon et al.   PLoS One

Impaired Collagen Biosynthesis and Cross‐linking in Aorta of Patients With Bicuspid Aortic Valve

(2013) Dick Wågsäter et al.   Journal of the American Heart Association

Fibroblasts in post-infarction inflammation and cardiac repair

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Immunohistochemical detection of differentially localized up-regulation of lysyl oxidase and down-regulation of matrix metalloproteinase-1 in rhesus monkey model of chronic myocardial infarction

(2012) Yuping Xie et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice

(2012) Haruya Ohmura et al.   HYPERTENSION RESEARCH

Myofibroblasts in the Infarct Area: Concepts and Challenges

(2012) Evangelos P. Daskalopoulos et al.   MICROSCOPY AND MICROANALYSIS

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

(2012) Karl T. Weber et al.   Nature Reviews Cardiology

Calcineurin Splicing Variant Calcineurin Aβ1 Improves Cardiac Function After Myocardial Infarction Without Inducing Hypertrophy

(2011) Leanne E. Felkin et al.   CIRCULATION

Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling

(2011) Tetyana G. Voloshenyuk et al.   CYTOKINE

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

(2011) C. C.-L. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction

(2010) Sih Min Tan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects

(2010) Begoña López et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Targeting Fibrosis for the Treatment of Heart Failure: A Role for Transforming Growth Factor-β

(2010) Amanda J Edgley et al.   Cardiovascular Therapeutics

Temporal and Spatial Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases Following Myocardial Infarction

(2010) Merry L. Lindsey et al.   Cardiovascular Therapeutics

Transforming growth factor (TGF)-β signaling in cardiac remodeling

(2010) Marcin Dobaczewski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myocardial lysyl oxidase regulation of cardiac remodeling in a murine model of diet-induced metabolic syndrome

(2009) Sherma Zibadi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Inhibition of transforming growth factor-β signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart

(2009) Jason A. Lucas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Bioreductively Activated Lysyl Oxidase Inhibitors against Hypoxic Tumours

(2009) Carlotta Granchi et al.   ChemMedChem

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology

Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction

(2008) Stefan Frantz et al.   BASIC RESEARCH IN CARDIOLOGY

A synthetic peptide from transforming growth factor- 1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats

(2008) N. Hermida et al.   CARDIOVASCULAR RESEARCH

Transforming Growth Factor-β Blockade Down-Regulates the Renin-Angiotensin System and Modifies Cardiac Remodeling after Myocardial Infarction

(2008) Leigh J. Ellmers et al.   ENDOCRINOLOGY