Transgenic mice overexpressing desmocollin-2 (DSC2) develop cardiomyopathy associated with myocardial inflammation and fibrotic remodeling
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Transgenic mice overexpressing desmocollin-2 (DSC2) develop cardiomyopathy associated with myocardial inflammation and fibrotic remodeling
Authors
Keywords
Mouse models, Heart, Gene expression, Genetically modified animals, Cardiomyopathies, Fibrosis, Inflammation, Hyperexpression techniques
Journal
PLoS One
Volume 12, Issue 3, Pages e0174019
Publisher
Public Library of Science (PLoS)
Online
2017-03-25
DOI
10.1371/journal.pone.0174019
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mutations inFLNCare Associated with Familial Restrictive Cardiomyopathy
- (2016) Andreas Brodehl et al. HUMAN MUTATION
- Novel regulators of cardiac inflammation: Matricellular proteins expand their repertoire
- (2016) Marieke Rienks et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Homozygous Desmocollin-2 Mutations and Arrhythmogenic Cardiomyopathy
- (2015) Alessandra Lorenzon et al. AMERICAN JOURNAL OF CARDIOLOGY
- Complement system modulation as a target for treatment of arrhythmogenic cardiomyopathy
- (2015) Manolis Mavroidis et al. BASIC RESEARCH IN CARDIOLOGY
- Desmosome regulation and signaling in disease
- (2015) Joshua A. Broussard et al. CELL AND TISSUE RESEARCH
- Loss of Cardiomyocyte Integrin-Linked Kinase Produces an Arrhythmogenic Cardiomyopathy in Mice
- (2015) Khai Le Quang et al. Circulation-Arrhythmia and Electrophysiology
- Dsprul: A spontaneous mouse mutation in desmoplakin as a model of Carvajal-Huerta syndrome
- (2015) C. Herbert Pratt et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Normalization of Naxos plakoglobin levels restores cardiac function in mice
- (2015) Zhiwei Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Exercise Triggers ARVC Phenotype in Mice Expressing a Disease-Causing Mutated Version of Human Plakophilin-2
- (2015) Francisco M. Cruz et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- The Effects of Knockdown of Rho-Associated Kinase 1 and Zipper-Interacting Protein Kinase on Gene Expression and Function in Cultured Human Arterial Smooth Muscle Cells
- (2015) Jing-Ti Deng et al. PLoS One
- Desmosomes in the Heart: A Review of Clinical and Mechanistic Analyses
- (2014) Dipal M. Patel et al. CELL COMMUNICATION AND ADHESION
- Homozygous Founder Mutation in Desmocollin-2 ( DSC2 ) Causes Arrhythmogenic Cardiomyopathy in the Hutterite Population
- (2013) Brenda Gerull et al. Circulation-Cardiovascular Genetics
- HSulf sulfatases catalyze processive and oriented 6-O-desulfation of heparan sulfate that differentially regulates fibroblast growth factor activity
- (2013) Amal Seffouh et al. FASEB JOURNAL
- Histological and ultrastructural abnormalities in murine desmoglein 2-mutant hearts
- (2012) Sebastian Kant et al. CELL AND TISSUE RESEARCH
- Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study
- (2012) John Gomes et al. EUROPEAN HEART JOURNAL
- Arrhythmogenic right ventricular cardiomyopathy: severe structural alterations are associated with inflammation
- (2012) Oscar Campuzano et al. JOURNAL OF CLINICAL PATHOLOGY
- Desmoglein 2 mutant mice develop cardiac fibrosis and dilation
- (2011) Claudia A. Krusche et al. BASIC RESEARCH IN CARDIOLOGY
- Molecular changes in the heart of a severe case of arrhythmogenic right ventricular cardiomyopathy caused by a desmoglein-2 null allele
- (2011) Katja Gehmlich et al. CARDIOVASCULAR PATHOLOGY
- Desmosomes
- (2011) Adi D. Dubash et al. CURRENT BIOLOGY
- Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy
- (2011) Deqiang Li et al. HUMAN MOLECULAR GENETICS
- Early inflammatory response during the development of right ventricular heart failure in a rat model
- (2010) Maria E. Campian et al. EUROPEAN JOURNAL OF HEART FAILURE
- Assessment of inflammation in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia
- (2010) Maria E. Campian et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- De novo desmin-mutation N116S is associated with arrhythmogenic right ventricular cardiomyopathy
- (2010) Baerbel Klauke et al. HUMAN MOLECULAR GENETICS
- Cardiomyocyte-targeted overexpression of the coxsackie–adenovirus receptor causes a cardiomyopathy in association with β-catenin signaling
- (2010) Laura Caruso et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Compound and Digenic Heterozygosity Contributes to Arrhythmogenic Right Ventricular Cardiomyopathy
- (2010) Tianhong Xu et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Myocyte necrosis underlies progressive myocardial dystrophy in mousedsg2-related arrhythmogenic right ventricular cardiomyopathy
- (2009) Kalliopi Pilichou et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The role of osteopontin in inflammatory processes
- (2009) Susan Amanda Lund et al. Journal of Cell Communication and Signaling
- Hyper-adhesion: a new concept in cell–cell adhesion
- (2008) David Garrod et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Periostin as a Heterofunctional Regulator of Cardiac Development and Disease
- (2008) Simon Conway et al. CURRENT GENOMICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More