Translational Application of Circulating DNA in Oncology: Review of the Last Decades Achievements

Effect of systemic treatment on the micronuclei frequency in the peripheral blood of patients with metastatic colorectal cancer

(2019) Taxiarchis Nikolouzakis et al.   Oncology Letters

Identification of extracellular vesicles and characterization of miRNA expression profiles in human blastocoel fluid

(2019) R. Battaglia et al.   Scientific Reports

Gut Microbiota and Cancer: From Pathogenesis to Therapy

(2019) Silvia Vivarelli et al.   Cancers

Clinical Utilization Pattern of Liquid Biopsies (LB) to Detect Actionable Driver Mutations, Guide Treatment Decisions and Monitor Disease Burden During Treatment of 33 Metastatic Colorectal Cancer (mCRC) Patients (pts) at a Fox Chase Cancer Center GI Oncology Subspecialty Clinic

(2019) Pooja Ghatalia et al.   Frontiers in Oncology

KCNMA1 Expression is Downregulated in Colorectal Cancer via Epigenetic Mechanisms

(2019) Maria Sofia Basile et al.   Cancers

Exosomes: biogenesis, biologic function and clinical potential

(2019) Yuan Zhang et al.   Cell and Bioscience

Clinical Implications of Circulating Tumor DNA Tumor Mutational Burden (ctDNA TMB) in Non‐Small Cell Lung Cancer

(2019) Young Kwang Chae et al.   ONCOLOGIST

Prognostic significance of deregulated microRNAs in uveal melanomas

(2019) Luca Falzone et al.   Molecular Medicine Reports

The interplay of circulating tumor DNA and chromatin modification, therapeutic resistance, and metastasis

(2019) Lei Zhang et al.   Molecular Cancer

Combining 18F-FDG PET/CT-based Metabolically Active Tumor Volume and Circulating Cell-free DNA Significantly Improves Outcome Prediction in Chemorefractory Metastatic Colorectal Cancer

(2019) Erwin Woff et al.   JOURNAL OF NUCLEAR MEDICINE

Prediction and monitoring of relapse in stage III melanoma using circulating tumor DNA

(2019) L Tan et al.   ANNALS OF ONCOLOGY

Life and death of circulating cell-free DNA

(2019) Anatoli Kustanovich et al.   CANCER BIOLOGY & THERAPY

TP53, EGFR and PIK3CA gene variations observed as prominent biomarkers in breast and lung cancer by plasma cell-free DNA genomic testing

(2019) Savli Hakan et al.   JOURNAL OF BIOTECHNOLOGY

Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma

(2019) Marie-Lisa Eich et al.   MODERN PATHOLOGY

Serial Monitoring of Circulating Tumor DNA in Patients With Metastatic Colorectal Cancer to Predict the Therapeutic Response

(2019) Ning Jia et al.   Frontiers in Genetics

Identification of Novel MicroRNAs and Their Diagnostic and Prognostic Significance in Oral Cancer

(2019) Falzone et al.   Cancers

Detection of ERBB2 (HER2) Gene Amplification Events in Cell-Free DNA and Response to Anti-HER2 Agents in a Large Asian Cancer Patient Cohort

(2019) Jeeyun Lee et al.   Frontiers in Oncology

Inflammation and Metabolism in Cancer Cell—Mitochondria Key Player

(2019) Monica Neagu et al.   Frontiers in Oncology

PIK3CA hotspot mutations in circulating tumor cells and paired circulating tumor DNA in breast cancer: a direct comparison study

(2019) Eleni Tzanikou et al.   Molecular Oncology

Characterization of the Pathophysiological Role of CD47 in Uveal Melanoma

(2019) Maria Cristina Petralia et al.   MOLECULES

The analysis of miRNA expression profiling datasets reveals inverse microRNA patterns in glioblastoma and Alzheimer's disease

(2019) Saverio Candido et al.   ONCOLOGY REPORTS

Discovery of potent telomerase activators: Unfolding new therapeutic and anti-aging perspectives

(2019) Dimitris Tsoukalas et al.   Molecular Medicine Reports

Adverse and hormetic effects in rats exposed for 12 months to low dose mixture of 13 chemicals: RLRS part III

(2019) Anca Oana Docea et al.   TOXICOLOGY LETTERS

Noncoding RNAs in Extracellular Fluids as Cancer Biomarkers: The New Frontier of Liquid Biopsies

(2019) Barbara Pardini et al.   Cancers

Current and Future Trends on Diagnosis and Prognosis of Glioblastoma: From Molecular Biology to Proteomics

(2019) Silantyev et al.   Cells

How liquid biopsies can change clinical practice in oncology

(2019) G Siravegna et al.   ANNALS OF ONCOLOGY

Genotoxic, cytotoxic, and cytopathological effects in rats exposed for 18 months to a mixture of 13 chemicals in doses below NOAEL levels

(2019) Aristidis Tsatsakis et al.   TOXICOLOGY LETTERS

Integrated analysis of colorectal cancer microRNA datasets: identification of microRNAs associated with tumor development

(2018) Luca Falzone et al.   Aging-US

Frequencies and expression levels of programmed death ligand 1 (PD-L1) in circulating tumor RNA (ctRNA) in various cancer types

(2018) Toshiyuki Ishiba et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients

(2018) Ashleigh C. McEvoy et al.   BMC CANCER

Cancer screening in the United States, 2018: A review of current American Cancer Society guidelines and current issues in cancer screening

(2018) Robert A. Smith et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Liquid Biopsies and Cancer Immunotherapy

(2018) Jonathan R. Thompson et al.   CANCER JOURNAL

The Role of Circulating Tumor DNA in Renal Cell Carcinoma

(2018) Paulo G. Bergerot et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Molecular profiling of lung cancer specimens and liquid biopsies using MALDI-TOF mass spectrometry

(2018) Eleonora Bonaparte et al.   Diagnostic Pathology

Dynamics of multiple resistance mechanisms in plasma DNA during EGFR‐targeted therapies in non‐small cell lung cancer

(2018) Dana Wai Yi Tsui et al.   EMBO Molecular Medicine

Circulating Cell-Free DNA as a Prognostic and Molecular Marker for Patients with Brain Tumors under Perillyl Alcohol-Based Therapy

(2018) Giselle Faria et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cutaneous melanoma: From pathogenesis to therapy (Review)

(2018) Giulia Leonardi et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Correlation between circulating cell-free PIK3CA tumor DNA levels and treatment response in patients with PIK3CA -mutated metastatic breast cancer

(2018) Annette R. Kodahl et al.   Molecular Oncology

Improving diagnosis, prognosis and prediction by using biomarkers in CRC patients (Review)

(2018) Taxiarchis Nikolouzakis et al.   ONCOLOGY REPORTS

‘Liquid biopsy’ for cancer promises early detection

(2018) Jocelyn Kaiser   SCIENCE

Detection and localization of surgically resectable cancers with a multi-analyte blood test

(2018) Joshua D. Cohen et al.   SCIENCE

Overexpression of macrophage migration inhibitory factor and functionally‑related genes, D‑DT, CD74, CD44, CXCR2 and CXCR4, in glioblastoma

(2018) Mario Presti et al.   Oncology Letters

Circulating Tumor DNA Genomics Correlate with Resistance to Abiraterone and Enzalutamide in Prostate Cancer

(2018) Matti Annala et al.   Cancer Discovery

Monitoring circulating tumor DNA revealed dynamic changes in KRAS status in patients with metastatic colorectal cancer

(2018) Yuji Takayama et al.   Oncotarget

Role of circulating tumor DNA in the management of early-stage lung cancer

(2018) Heng Zhao et al.   Thoracic Cancer

Advances in liquid biopsy approaches for early detection and monitoring of cancer

(2018) Anna Babayan et al.   Genome Medicine

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

(2018) Simeon U Springer et al.   eLife

Liquid biopsy for early stage lung cancer

(2018) Wenhua Liang et al.   Journal of Thoracic Disease

Diagnostic accuracy of droplet digital PCR for detection of EGFR T790M mutation in circulating tumor DNA

(2018) Rui Zhang et al.   Cancer Management and Research

Improved EGFR mutation detection using combined exosomal RNA and circulating tumor DNA in NSCLC patient plasma

(2018) A K Krug et al.   ANNALS OF ONCOLOGY

Utility of circulating tumor DNA in cancer diagnostics with emphasis on early detection

(2018) Clare Fiala et al.   BMC Medicine

Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review)

(2018) Alessia Finotti et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Anticancer and Differentiation Properties of the Nitric Oxide Derivative of Lopinavir in Human Glioblastoma Cells

(2018) Maria Basile et al.   MOLECULES

Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity

(2018) Ni Ni Moe Myint et al.   Cell Death & Disease

Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors

(2018) Lise Barlebo Ahlborn et al.   Oncotarget

MMP-9 as a Candidate Marker of Response to BRAF Inhibitors in Melanoma Patients With BRAFV600E Mutation Detected in Circulating-Free DNA

(2018) Rossella Salemi et al.   Frontiers in Pharmacology

Assessing the Impact of Circulating Tumor DNA (ctDNA) in Patients With Colorectal Cancer: Separating Fact From Fiction

(2018) Emmanuel Gabriel et al.   Frontiers in Oncology

Detection of HER2-positive Circulating Tumor Cells Using the LiquidBiopsy System in Breast Cancer

(2018) Weirong Chen et al.   Clinical Breast Cancer

COSMIC: the Catalogue Of Somatic Mutations In Cancer

(2018) John G Tate et al.   NUCLEIC ACIDS RESEARCH

Analysis of KRAS, NRAS and BRAF mutational profile by combination of in-tube hybridization and universal tag-microarray in tumor tissue and plasma of colorectal cancer patients

(2018) Francesco Damin et al.   PLoS One

Liquid biopsy in ovarian cancer: the potential of circulating miRNAs and exosomes

(2018) Lydia Giannopoulou et al.   Translational Research

Identification of rare levels of methylated tumor DNA fragments using an optimized bias based pre-amplification-digital droplet PCR (OBBPA-ddPCR)

(2018) Mario Menschikowski et al.   Oncotarget

Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer

(2018) Hiroki Osumi et al.   Cancer Medicine

Evolution of Cancer Pharmacological Treatments at the Turn of the Third Millennium

(2018) Luca Falzone et al.   Frontiers in Pharmacology

The Potential Clinical Utility of Circulating Tumor DNA in Esophageal Adenocarcinoma: From Early Detection to Therapy

(2018) Juliann E. Kosovec et al.   Frontiers in Oncology

Hormetic Neurobehavioral effects of low dose toxic chemical mixtures in real-life risk simulation (RLRS) in rats

(2018) Aristidis M. Tsatsakis et al.   FOOD AND CHEMICAL TOXICOLOGY

Evaluation of three advanced methodologies, COLD-PCR, microarray and ddPCR, for identifying the mutational status by liquid biopsies in metastatic colorectal cancer patients

(2018) Silvia Galbiati et al.   CLINICA CHIMICA ACTA

Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer

(2017) Emil Christensen et al.   EUROPEAN UROLOGY

Recent advances in circulating tumor cells and cell-free DNA in metastatic prostate cancer: a review

(2017) Sunil Parimi et al.   Expert Review of Anticancer Therapy

Droplet-based digital PCR and next generation sequencing for monitoring circulating tumor DNA: a cancer diagnostic perspective

(2017) Mathilde Postel et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Identification of novel mutations in Japanese ovarian clear cell carcinoma patients using optimized targeted NGS for clinical diagnosis

(2017) Yoshiaki Maru et al.   GYNECOLOGIC ONCOLOGY

Study of Preanalytic and Analytic Variables for Clinical Next-Generation Sequencing of Circulating Cell-Free Nucleic Acid

(2017) Meenakshi Mehrotra et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Applications of DNA-Based Liquid Biopsy for Central Nervous System Neoplasms

(2017) Joanna Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

De-novo and acquired resistance to immune checkpoint targeting

(2017) Nicholas L Syn et al.   LANCET ONCOLOGY

Liquid biopsy: a step forward towards precision medicine in urologic malignancies

(2017) Ashley Di Meo et al.   Molecular Cancer

Current and Emerging Applications of Droplet Digital PCR in Oncology

(2017) Susana Olmedillas-López et al.   Molecular Diagnosis & Therapy

The risk of HCV infection among health-care workers and its association with extrahepatic manifestations

(2017) Adriana Garozzo et al.   Molecular Medicine Reports

Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides

(2017) Venerando Rapisarda et al.   Molecular Medicine Reports

Immunological effects of occupational exposure to lead

(2017) Concettina Fenga et al.   Molecular Medicine Reports

NF-κB inhibition is associated with OPN/MMP-9 downregulation in cutaneous melanoma

(2017) Claudio Guarneri et al.   ONCOLOGY REPORTS

Feasibility of monitoring advanced melanoma patients using cell-free DNA from plasma

(2017) Tara C. Gangadhar et al.   Pigment Cell & Melanoma Research

Intratumor and Intertumor Heterogeneity in Melanoma

(2017) Tomasz M. Grzywa et al.   Translational Oncology

Liquid biopsy: unlocking the potentials of cell-free DNA

(2017) David Chu et al.   VIRCHOWS ARCHIV

Clinical and biological significance of circulating tumor cells, circulating tumor DNA, and exosomes as biomarkers in colorectal cancer

(2017) Shiyu Jia et al.   Oncotarget

Prognostic value of EGFR and KRAS in circulating tumor DNA in patients with advanced non-small cell lung cancer: a systematic review and meta-analysis

(2017) Gaowei Fan et al.   Oncotarget

Environment and bladder cancer: molecular analysis by interaction networks

(2017) Andrea Polo et al.   Oncotarget

Cross-Platform Comparison of Four Leading Technologies for Detecting EGFR Mutations in Circulating Tumor DNA from Non-Small Cell Lung Carcinoma Patient Plasma

(2017) Ting Xu et al.   Theranostics

Lactobacillus rhamnosus GG: An Overview to Explore the Rationale of Its Use in Cancer

(2017) Giuseppe L. Banna et al.   Frontiers in Pharmacology

CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function

(2017) et al.   Genes

Association Of Plasma And Urinary Mutant DNA With Clinical Outcomes In Muscle Invasive Bladder Cancer

(2017) K. M. Patel et al.   Scientific Reports

Genomic and Epigenomic Alterations in Cancer

(2016) Balabhadrapatruni V.S.K. Chakravarthi et al.   AMERICAN JOURNAL OF PATHOLOGY

Characterization of the cell-free DNA released by cultured cancer cells

(2016) Abel Jacobus Bronkhorst et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Origins, structures, and functions of circulating DNA in oncology

(2016) A. R. Thierry et al.   CANCER AND METASTASIS REVIEWS

Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin

(2016) Matthew W. Snyder et al.   CELL

A historical and evolutionary perspective on the biological significance of circulating DNA and extracellular vesicles

(2016) Janine Aucamp et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Detection of TP53/PIK3CA Mutations in Cell-Free Plasma DNA From Metastatic Breast Cancer Patients Using Next Generation Sequencing

(2016) Chiaki Nakauchi et al.   Clinical Breast Cancer

Circulating Tumor DNA as an Early Indicator of Response to T-cell Transfer Immunotherapy in Metastatic Melanoma

(2016) Liqiang Xi et al.   CLINICAL CANCER RESEARCH

Circulating Tumor DNA as a Cancer Biomarker: Fact or Fiction?

(2016) F. Leung et al.   CLINICAL CHEMISTRY

A Study of Hypermethylated Circulating Tumor DNA as a Universal Colorectal Cancer Biomarker

(2016) S. Garrigou et al.   CLINICAL CHEMISTRY

Genomic complexity of urothelial bladder cancer revealed in urinary cfDNA

(2016) Fiona S Togneri et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genomic Alterations in Liquid Biopsies from Patients with Bladder Cancer

(2016) Karin Birkenkamp-Demtröder et al.   EUROPEAN UROLOGY

New challenges in risk assessment of chemicals when simulating real exposure scenarios; simultaneous multi-chemicals' low dose exposure

(2016) Aristidis M. Tsatsakis et al.   FOOD AND CHEMICAL TOXICOLOGY

Monitoring the HER2 copy number status in circulating tumor DNA by droplet digital PCR in patients with gastric cancer

(2016) Katsutoshi Shoda et al.   Gastric Cancer

Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach

(2016) AM Tsatsakis et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Occupational exposure to carcinogens: Benzene, pesticides and fibers

(2016) Luca Falzone et al.   Molecular Medicine Reports

Nucleosome-free DNA regions differentially affect distant communication in chromatin

(2016) Ekaterina V. Nizovtseva et al.   NUCLEIC ACIDS RESEARCH

Clusters of circulating tumor cells traverse capillary-sized vessels

(2016) Sam H. Au et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Change in FDG-PET Signal and Plasma Cell-Free DNA Level Predicts Erlotinib Response in EGFR Wild-Type NSCLC Patients

(2016) Anne Winther-Larsen et al.   Translational Oncology

The Long and Short of Circulating Cell-Free DNA and the Ins and Outs of Molecular Diagnostics

(2016) Peiyong Jiang et al.   TRENDS IN GENETICS

Fluoro-edenite induces fibulin-3 overexpression in non-malignant human mesothelial cells

(2016) Venerando Rapisarda et al.   Oncology Letters

Diagnosis of pancreatic lesions collected by endoscopic ultrasound-guided fine-needle aspiration using next-generation sequencing

(2016) Eri Kameta et al.   Oncology Letters

Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer

(2016) Peter Ulz et al.   Nature Communications

Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer

(2016) Evelyn Kidess-Sigal et al.   Oncotarget

Alu methylation serves as a biomarker for non-invasive diagnosis of glioma

(2016) Jian Chen et al.   Oncotarget

Epithelial-to-mesenchymal transition leads to loss of EpCAM and different physical properties in circulating tumor cells from metastatic breast cancer

(2016) Kyung-A Hyun et al.   Oncotarget

Computational identification of microRNAs associated to both epithelial to mesenchymal transition and NGAL/MMP-9 pathways in bladder cancer

(2016) Luca Falzone et al.   Oncotarget

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

(2016) James A. McCubrey et al.   Oncotarget

Colon Cancer Cells Gene Expression Signature As Response to 5- Fluorouracil, Oxaliplatin, and Folinic Acid Treatment

(2016) Carolina Negrei et al.   Frontiers in Pharmacology

Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer

(2016) Howard I. Scher et al.   JAMA Oncology

Genomic Alterations in Cell-Free DNA and Enzalutamide Resistance in Castration-Resistant Prostate Cancer

(2016) Alexander W. Wyatt et al.   JAMA Oncology

Prospective Validation of Rapid Plasma Genotyping for the Detection ofEGFRandKRASMutations in Advanced Lung Cancer

(2016) Adrian G. Sacher et al.   JAMA Oncology

Monitoring PD-L1 positive circulating tumor cells in non-small cell lung cancer patients treated with the PD-1 inhibitor Nivolumab

(2016) Chiara Nicolazzo et al.   Scientific Reports

Initial diagnosis of chronic myelogenous leukemia based on quantification of M-BCR status using droplet digital PCR

(2015) Helen Louise Lund et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Circulating cell-free AR and CYP17A1 copy number variations may associate with outcome of metastatic castration-resistant prostate cancer patients treated with abiraterone

(2015) S Salvi et al.   BRITISH JOURNAL OF CANCER

Detection of BRAF-V600E and V600K in melanoma circulating tumour cells by droplet digital PCR

(2015) Anna L. Reid et al.   CLINICAL BIOCHEMISTRY

Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer

(2015) A. A. Azad et al.   CLINICAL CANCER RESEARCH

Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease

(2015) Eleonor Olsson et al.   EMBO Molecular Medicine

Frequent expression of PD-L1 on circulating breast cancer cells

(2015) Martine Mazel et al.   Molecular Oncology

Plasma AR and abiraterone-resistant prostate cancer

(2015) Alessandro Romanel et al.   Science Translational Medicine

Urinary Cell-Free DNA Quantification as Non-Invasive Biomarker in Patients with Bladder Cancer

(2015) Antonin Brisuda et al.   UROLOGIA INTERNATIONALIS

Correlation between the overexpression of Yin Yang 1 and the expression levels of miRNAs in Burkitt's lymphoma: A computational study

(2015) SAMEH HAFSI et al.   Oncology Letters

Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas

(2015) O. A. Zill et al.   Cancer Discovery

An epigenetic biomarker combination of PCDH17 and POU4F2 detects bladder cancer accurately by methylation analyses of urine sediment DNA in Han Chinese

(2015) Yongqiang Wang et al.   Oncotarget

Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA

(2015) Richard B. Lanman et al.   PLoS One

SNPase-ARMS qPCR: Ultrasensitive Mutation-Based Detection of Cell-Free Tumor DNA in Melanoma Patients

(2015) Julia Stadler et al.   PLoS One

MET amplification as a potential therapeutic target in gastric cancer

(2015) Hisato Kawakami et al.   Oncotarget

Circulating tumor cells and circulating tumor DNA for precision medicine: dream or reality?

(2014) M. Ignatiadis et al.   ANNALS OF ONCOLOGY

Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer

(2014) F. Rothé et al.   ANNALS OF ONCOLOGY

Chromosomal Instability in Cell-Free DNA Is a Serum Biomarker for Prostate Cancer

(2014) E. Schutz et al.   CLINICAL CHEMISTRY

Quantitative Cell-Free Circulating BRAFV600E Mutation Analysis by Use of Droplet Digital PCR in the Follow-up of Patients with Melanoma Being Treated with BRAF Inhibitors

(2014) M. F. Sanmamed et al.   CLINICAL CHEMISTRY

Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients

(2014) Jordan Madic et al.   INTERNATIONAL JOURNAL OF CANCER

An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage

(2014) Aaron M Newman et al.   NATURE MEDICINE

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

(2014) Emmanuel S. Antonarakis et al.   NEW ENGLAND JOURNAL OF MEDICINE

Assessment of EGFR Mutations in Circulating Tumor Cell Preparations from NSCLC Patients by Next Generation Sequencing: Toward a Real-Time Liquid Biopsy for Treatment

(2014) Antonio Marchetti et al.   PLoS One

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load

(2014) Florent Mouliere et al.   Translational Oncology

Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA

(2014) D. A. Haber et al.   Cancer Discovery

Isolation and Molecular Characterization of Circulating Melanoma Cells

(2014) Xi Luo et al.   Cell Reports

The correlation between cell-free DNA and tumour burden was estimated by PET/CT in patients with advanced NSCLC

(2013) A D Nygaard et al.   BRITISH JOURNAL OF CANCER

Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing

(2013) E. Heitzer et al.   CANCER RESEARCH

Quantification of Plasma Cell-Free DNA1in Predicting Therapeutic Efficacy of Sorafenib on Metastatic Clear Cell Renal Cell Carcinoma

(2013) Gang Feng et al.   DISEASE MARKERS

Hypermethylation of TWIST1 and NID2 in Tumor Tissues and Voided Urine in Urinary Bladder Cancer Patients

(2013) Zeynep Yegin et al.   DNA AND CELL BIOLOGY

Diagnostic and prognostic value of circulating tumor-related DNA in cancer patients

(2013) Diego M Marzese et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

“Reactive” response evaluation of primary human astrocytes after methylmercury exposure

(2013) Giuseppe A. Malfa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

(2013) Muhammed Murtaza et al.   NATURE

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Absolute quantification by droplet digital PCR versus analog real-time PCR

(2013) Christopher M Hindson et al.   NATURE METHODS

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

(2013) Sarah-Jane Dawson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Monitoring of Plasma Cell-Free DNA in Predicting Postoperative Recurrence of Clear Cell Renal Cell Carcinoma

(2013) JingJing Wan et al.   UROLOGIA INTERNATIONALIS

Alu elements: an intrinsic source of human genome instability

(2013) Catherine Ade et al.   Current Opinion in Virology

Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing

(2013) Ellen Heitzer et al.   Genome Medicine

Next-generation sequencing in the clinical genetic screening of patients with pheochromocytoma and paraganglioma

(2013) Joakim Crona et al.   Endocrine Connections

Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level

(2012) K Sakaizawa et al.   BRITISH JOURNAL OF CANCER

Global DNA hypomethylation in cancer: review of validated methods and clinical significance

(2012) Estela G. Toraño et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Genome-wide nucleosome positioning during embryonic stem cell development

(2012) Vladimir B Teif et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA

(2012) T. Forshew et al.   Science Translational Medicine

Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing

(2012) R. J. Leary et al.   Science Translational Medicine

Urine Cell-Free DNA integrity as a marker for early bladder cancer diagnosis: Preliminary data

(2012) Valentina Casadio et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Evaluation of a Droplet Digital Polymerase Chain Reaction Format for DNA Copy Number Quantification

(2011) Leonardo B. Pinheiro et al.   ANALYTICAL CHEMISTRY

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

(2011) Benjamin J. Hindson et al.   ANALYTICAL CHEMISTRY

Genomic analysis of circulating cell-free DNA infers breast cancer dormancy

(2011) J. A. Shaw et al.   GENOME RESEARCH

Determinants of nucleosome organization in primary human cells

(2011) Anton Valouev et al.   NATURE

Detection and quantification of rare mutations with massively parallel sequencing

(2011) I. Kinde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Universal noninvasive detection of solid organ transplant rejection

(2011) T. M. Snyder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

(2010) David J. McBride et al.   GENES CHROMOSOMES & CANCER

Mass spectrometric based analysis, characterization and applications of circulating cell free DNA isolated from human body fluids

(2010) Vaneet K. Sharma et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Performance of Epigenetic Markers SEPT9 and ALX4 in Plasma for Detection of Colorectal Precancerous Lesions

(2010) Marc Tänzer et al.   PLoS One

Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing

(2010) R. J. Leary et al.   Science Translational Medicine

Next Generation DNA Sequencing and the Future of Genomic Medicine

(2010) Matthew W. Anderson et al.   Genes

TP53 R249S Mutations, Exposure to Aflatoxin, and Occurrence of Hepatocellular Carcinoma in a Cohort of Chronic Hepatitis B Virus Carriers from Qidong, China

(2009) K. Szymanska et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

Identification and Validation of the Methylated TWIST1 and NID2 Genes through Real-Time Methylation-Specific Polymerase Chain Reaction Assays for the Noninvasive Detection of Primary Bladder Cancer in Urine Samples

(2009) Isabelle Renard et al.   EUROPEAN UROLOGY

Introduction: Unknown Primary Cancer

(2009) F. Anthony Greco et al.   SEMINARS IN ONCOLOGY

Next-generation DNA sequencing

(2008) Jay Shendure et al.   NATURE BIOTECHNOLOGY

Circulating mutant DNA to assess tumor dynamics

(2008) Frank Diehl et al.   NATURE MEDICINE

Sensitive Detection of Colorectal Cancer in Peripheral Blood by Septin 9 DNA Methylation Assay

(2008) Robert Grützmann et al.   PLoS One