SNPase-ARMS qPCR: Ultrasensitive Mutation-Based Detection of Cell-Free Tumor DNA in Melanoma Patients

Large multiallelic copy number variations in humans

(2015) Robert E Handsaker et al.   NATURE GENETICS

Molecular Subtypes in Stage II-III Colon Cancer Defined by Genomic Instability: Early Recurrence-Risk Associated with a High Copy-Number Variation and Loss of RUNX3 and CDKN2A

(2015) Marianne Berg et al.   PLoS One

High-sensitivity PCR method for detecting BRAF V600Emutations in metastatic colorectal cancer using LNA/DNA chimeras to block wild-type alleles

(2014) Dong Chen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Mapping the deletion endpoints in individuals with 22q11.2 Deletion Syndrome by droplet digital PCR

(2014) Vicki J Hwang et al.   BMC Medical Genetics

Noninvasive Detection of Response and Resistance in EGFR-Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA

(2014) G. R. Oxnard et al.   CLINICAL CANCER RESEARCH

Detection of Cancer DNA in Plasma of Patients with Early-Stage Breast Cancer

(2014) J. A. Beaver et al.   CLINICAL CANCER RESEARCH

Quantitative Cell-Free Circulating BRAFV600E Mutation Analysis by Use of Droplet Digital PCR in the Follow-up of Patients with Melanoma Being Treated with BRAF Inhibitors

(2014) M. F. Sanmamed et al.   CLINICAL CHEMISTRY

Liquid Biopsies: Genotyping Circulating Tumor DNA

(2014) Luis A. Diaz et al.   JOURNAL OF CLINICAL ONCOLOGY

Detecting cancer by monitoring circulating tumor DNA

(2014) Paul T Spellman et al.   NATURE MEDICINE

An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage

(2014) Aaron M Newman et al.   NATURE MEDICINE

Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA

(2014) Alain R Thierry et al.   NATURE MEDICINE

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load

(2014) Florent Mouliere et al.   Translational Oncology

Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA

(2014) D. A. Haber et al.   Cancer Discovery

Efficacy of Intermittent Combined RAF and MEK Inhibition in a Patient with Concurrent BRAF- and NRAS-Mutant Malignancies

(2014) O. Abdel-Wahab et al.   Cancer Discovery

Intrapatient Homogeneity of BRAFV600E Expression in Melanoma

(2013) Alexander M. Menzies et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Multiplex Picodroplet Digital PCR to Detect KRAS Mutations in Circulating DNA from the Plasma of Colorectal Cancer Patients

(2013) V. Taly et al.   CLINICAL CHEMISTRY

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

(2013) Sarah-Jane Dawson et al.   NEW ENGLAND JOURNAL OF MEDICINE

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation

(2013) Minakshi Guha et al.   PLoS One

Tumor Homogeneity between Primary and Metastatic Sites for BRAF Status in Metastatic Melanoma Determined by Immunohistochemical and Molecular Testing

(2013) Lucile Boursault et al.   PLoS One

Going with the Flow: From Circulating Tumor Cells to DNA

(2013) F.-C. Bidard et al.   Science Translational Medicine

Mutation-based detection and monitoring of cell-free tumor DNA in peripheral blood of cancer patients

(2012) L. Benesova et al.   ANALYTICAL BIOCHEMISTRY

Detection of Tumor PIK3CA Status in Metastatic Breast Cancer Using Peripheral Blood

(2012) M. J. Higgins et al.   CLINICAL CANCER RESEARCH

Comparison of a PNA Clamp PCR and an ARMS/Scorpion PCR Assay for the Detection of K-ras Mutations

(2012) Oddmund Nordgård et al.   DIAGNOSTIC MOLECULAR PATHOLOGY

Evaluation of qPCR curve analysis methods for reliable biomarker discovery: Bias, resolution, precision, and implications

(2012) Jan M. Ruijter et al.   METHODS

Multiparametric Analysis of Cell-Free DNA in Melanoma Patients

(2012) Francesca Salvianti et al.   PLoS One

BRAFV600E detection in melanoma is highly improved by COLD-PCR

(2011) Pamela Pinzani et al.   CLINICA CHIMICA ACTA

Quantitative Detection of EGFR Mutations in Circulating Tumor DNA Derived from Lung Adenocarcinomas

(2011) K. Taniguchi et al.   CLINICAL CANCER RESEARCH

A Novel Poisson Distribution–Based Approach for Testing Boundaries of Real-Time PCR Assays for Food Pathogen Quantification

(2011) PETER ROSSMANITH et al.   JOURNAL OF FOOD PROTECTION

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

(2011) Deniz Pekin et al.   LAB ON A CHIP

Detection of PIK3CA mutations in circulating free DNA in patients with breast cancer

(2010) Ruth E. Board et al.   BREAST CANCER RESEARCH AND TREATMENT

Allele specific Taqman-based real-time PCR assay to quantify circulating BRAFV600E mutated DNA in plasma of melanoma patients

(2010) Pamela Pinzani et al.   CLINICA CHIMICA ACTA

Cell-free DNA in the blood as a solid tumor biomarker—A critical appraisal of the literature

(2010) Klaus Jung et al.   CLINICA CHIMICA ACTA

BLAST+: architecture and applications

(2009) Christiam Camacho et al.   BMC BIOINFORMATICS

Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study

(2009) R E Board et al.   BRITISH JOURNAL OF CANCER

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Suppression of mTOR complex 2-dependent AKT phosphorylation in melanoma cells by combined treatment with rapamycin and LY294002

(2008) J. Werzowa et al.   BRITISH JOURNAL OF DERMATOLOGY

Multiplexed Assays for Detection of Mutations in PIK3CA

(2008) R. E. Board et al.   CLINICAL CHEMISTRY

Circulating mutant DNA to assess tumor dynamics

(2008) Frank Diehl et al.   NATURE MEDICINE

Comparative lesion sequencing provides insights into tumor evolution

(2008) S. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA