The Hemocompatibility of Nanoparticles: A Review of Cell–Nanoparticle Interactions and Hemostasis

BloodSurf 2017: News from the Blood-Biomaterial Frontier

(2019) Irini Sotiri et al.   Acta Biomaterialia

Red blood cells: the forgotten player in hemostasis and thrombosis

(2019) J. W. Weisel et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Immunomodulatory role of chitosan-based nanoparticles and oligosaccharides in cyclophosphamide treated mice

(2019) Jayesh Mudgal et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Silica nanoparticles trigger the vascular endothelial dysfunction and prethrombotic state via miR-451 directly regulating the IL6R signaling pathway

(2019) Lin Feng et al.   Particle and Fibre Toxicology

Direct effects of poly(ε-caprolactone) lipid-core nanocapsules on human immune cells

(2019) Silvana Sandri et al.   Nanomedicine

A coarse-grained red blood cell membrane model to study stomatocyte-discocyte-echinocyte morphologies

(2019) Nadeeshani Maheshika Geekiyanage et al.   PLoS One

Neutrophils in innate immunity and systems biology‐level approaches

(2019) Viktoria Rungelrath et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

The blood compatibility challenge. Part 3: Material associated activation of blood cascades and cells

(2019) Maud Gorbet et al.   Acta Biomaterialia

Cytokine production by human neutrophils: Revisiting the “dark side of the moon”

(2018) Nicola Tamassia et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Phosphatidylserine-exposing cells contribute to the hypercoagulable state in patients with multiple myeloma

(2018) Li Guo et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The Interplay Between Nanoparticles and Neutrophils

(2018) Ming-Hsien Lin et al.   Journal of Biomedical Nanotechnology

Which Dendrimer to Attain the Desired Properties? Focus on Phosphorhydrazone Dendrimers

(2018) Anne-Marie Caminade et al.   MOLECULES

Nanotechnology and primary hemostasis: Differential effects of nanoparticles on platelet responses

(2018) María Francisca Matus et al.   VASCULAR PHARMACOLOGY

Nanoparticle Properties Modulate Their Attachment and Effect on Carrier Red Blood Cells

(2018) Daniel C. Pan et al.   Scientific Reports

Significantly increased low shear rate viscosity, blood elastic modulus, and RBC aggregation in adults following cardiac surgery

(2018) Yi-Fan Wu et al.   Scientific Reports

Immunotoxicity of Silver Nanoparticles (AgNPs) on the Leukocytes of Common Bottlenose Dolphins (Tursiops truncatus)

(2018) Wen-Ta Li et al.   Scientific Reports

Hemodynamic Functionality of Transfused Red Blood Cells in the Microcirculation of Blood Recipients

(2018) Gregory Barshtein et al.   Frontiers in Physiology

Influence of particle size and shape on their margination and wall-adhesion: implications in drug delivery vehicle design across nano-to-micro scale

(2018) Michaela Cooley et al.   Nanoscale

Red blood cell aggregates and their effect on non-Newtonian blood viscosity at low hematocrit in a two-fluid low shear rate microfluidic system

(2018) Rym Mehri et al.   PLoS One

Nanotechnology-enabled materials for hemostatic and anti-infection treatments in orthopedic surgery

(2018) Haolin Sun et al.   International Journal of Nanomedicine

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

(2018) Vivian P. Vu et al.   Nature Nanotechnology

Evaluation of the in vitro and in vivo proinflammatory activities of gold (+) and gold (−) nanoparticles

(2017) Isabelle Durocher et al.   INFLAMMATION RESEARCH

Surface modification minimizes the toxicity of silver nanoparticles: an in vitro and in vivo study

(2017) Balaram Das et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Mononuclear phagocytes as a target, not a barrier, for drug delivery

(2017) Seok-Beom Yong et al.   JOURNAL OF CONTROLLED RELEASE

Fibrous nanocellulose, crystalline nanocellulose, carbon nanotubes, and crocidolite asbestos elicit disparate immune responses upon pharyngeal aspiration in mice

(2017) Eun-Jung Park et al.   Journal of Immunotoxicology

Avoiding the mononuclear phagocyte system using human albumin for mesoporous silica nanoparticle system

(2017) Sofia Nascimento dos Santos et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Advances in Alzheimer’s Diagnosis and Therapy: The Implications of Nanotechnology

(2017) Mohammad Javad Hajipour et al.   TRENDS IN BIOTECHNOLOGY

The effects of nanomaterials on blood coagulation in hemostasis and thrombosis

(2017) Jan Simak et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Nanoparticles: Properties, applications and toxicities

(2017) Ibrahim Khan et al.   Arabian Journal of Chemistry

Stroke Management: An Emerging Role of Nanotechnology

(2017) Deepaneeta Sarmah et al.   Micromachines

Human Lung Mononuclear Phagocytes in Health and Disease

(2017) Faezzah Baharom et al.   Frontiers in Immunology

In vivo and in vitro evaluation of hydroxyapatite nanoparticle morphology on the acute inflammatory response

(2016) Shiuli Pujari-Palmer et al.   BIOMATERIALS

Utilization of nanoparticle technology in rheumatoid arthritis treatment

(2016) Sanam Dolati et al.   BIOMEDICINE & PHARMACOTHERAPY

The role of leukocytes in thrombosis

(2016) Laura L. Swystun et al.   BLOOD

Protein corona over silver nanoparticles triggers conformational change of proteins and drop in bactericidal potential of nanoparticles: Polyethylene glycol capping as preventive strategy

(2016) Deependra Kumar Ban et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Hemorheological characteristics of red blood cells exposed to surface functionalized graphene quantum dots

(2016) Jeongho Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Cationic liposomes induce cell necrosis through lysosomal dysfunction and late-stage autophagic flux inhibition

(2016) Kaixuan Yang et al.   Nanomedicine

Gold nanoparticles induce apoptosis, endoplasmic reticulum stress events and cleavage of cytoskeletal proteins in human neutrophils

(2016) Claudie Noël et al.   TOXICOLOGY IN VITRO

The Nanopharmacology and Nanotoxicology of Nanomaterials: New Opportunities and Challenges

(2016) Anna Radomska et al.   Advances in Clinical and Experimental Medicine

Towards understanding of nanoparticle–protein corona

(2015) Cuicui Ge et al.   ARCHIVES OF TOXICOLOGY

Nanoparticles enhance the ability of human neutrophils to exert phagocytosis by a Syk-dependent mechanism

(2015) K. Babin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Protein Corona of Nanoparticles: Distinct Proteins Regulate the Cellular Uptake

(2015) Sandra Ritz et al.   BIOMACROMOLECULES

Nanotoxicity of Silver Nanoparticles to Red Blood Cells: Size Dependent Adsorption, Uptake, and Hemolytic Activity

(2015) Li Qiang Chen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The impact of cationic solid lipid nanoparticles on human neutrophil activation and formation of neutrophil extracellular traps (NETs)

(2015) Tsong-Long Hwang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Nanoparticle uptake: The phagocyte problem

(2015) Heather Herd Gustafson et al.   Nano Today

In vivo toxicity of cationic micelles and liposomes

(2015) Kristina Bram Knudsen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Eryptosis Indices as a Novel Predictive Parameter for Biocompatibility of Fe3O4 Magnetic Nanoparticles on Erythrocytes

(2015) Qian Ran et al.   Scientific Reports

Magnetic Nanoparticles in Cancer Theranostics

(2015) Oliviero L. Gobbo et al.   Theranostics

Evaluation of Hemagglutination Activity of Chitosan Nanoparticles Using Human Erythrocytes

(2015) Jefferson Muniz de Lima et al.   Biomed Research International

Leucocyte classification for leukaemia detection using image processing techniques

(2014) Lorenzo Putzu et al.   ARTIFICIAL INTELLIGENCE IN MEDICINE

Role for nanomaterial-autophagy interaction in neurodegenerative disease

(2014) Stephan T. Stern et al.   Autophagy

New perspectives on the thrombotic complications of haemolysis

(2014) Camilla L'Acqua et al.   BRITISH JOURNAL OF HAEMATOLOGY

Toxic effects of silver nanoparticles and nanowires on erythrocyte rheology

(2014) Min Jung Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Assessment of the toxic potential of graphene family nanomaterials

(2014) Xiaoqing Guo et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Endotoxins affect diverse biological activity of chitosans in matters of hemocompatibility and cytocompatibility

(2014) Andrea Nolte et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Non-Newtonian Flow of Blood in Arterioles: Consequences for Wall Shear Stress Measurements

(2014) Krishna Sriram et al.   MICROCIRCULATION

The unexpected effect of PEGylated gold nanoparticles on the primary function of erythrocytes

(2014) Zeng He et al.   Nanoscale

Engineered nanoparticles interacting with cells: size matters

(2014) Li Shang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Hemocompatibility evaluation of different silver nanoparticle concentrations employing a modified Chandler-loop in vitro assay on human blood

(2013) Stefanie Krajewski et al.   Acta Biomaterialia

Implementation of alternative test strategies for the safety assessment of engineered nanomaterials

(2013) A. E. Nel   JOURNAL OF INTERNAL MEDICINE

New Insights into the Role of Erythrocytes in Thrombus Formation

(2013) Dana Huskens et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Nanosize and Surface Charge Effects of Hydroxyapatite Nanoparticles on Red Blood Cell Suspensions

(2012) Yingchao Han et al.   ACS Applied Materials & Interfaces

Influence of Geometry, Porosity, and Surface Characteristics of Silica Nanoparticles on Acute Toxicity: Their Vasculature Effect and Tolerance Threshold

(2012) Tian Yu et al.   ACS Nano

The influence of nanodiamond on the oxygenation states and micro rheological properties of human red blood cells in vitro

(2012) Yu-Chung Lin   JOURNAL OF BIOMEDICAL OPTICS

Cationic PAMAM Dendrimers Disrupt Key Platelet Functions

(2012) Clinton F. Jones et al.   MOLECULAR PHARMACEUTICS

Impact of Silica Nanoparticle Design on Cellular Toxicity and Hemolytic Activity

(2011) Tian Yu et al.   ACS Nano

Interaction of Mesoporous Silica Nanoparticles with Human Red Blood Cell Membranes: Size and Surface Effects

(2011) Yannan Zhao et al.   ACS Nano

Effects of Cobalt Nanoparticles on Human T Cells In Vitro

(2011) Haitao Jiang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

The Effects of Oral Consumption of Selenium Nanoparticles on Chemotactic and Respiratory Burst Activities of Neutrophils in Comparison with Sodium Selenite in Sheep

(2011) Gholam Ali Kojouri et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Platelets at work in primary hemostasis

(2011) Katleen Broos et al.   BLOOD REVIEWS

Interactions of nanoparticles with plasma proteins: implication on clearance and toxicity of drug delivery systems

(2011) Priya Prakash Karmali et al.   Expert Opinion on Drug Delivery

Size-dependent in vivo toxicity of PEG-coated gold nanoparticles

(2011) Xiao-Dong Zhang et al.   International Journal of Nanomedicine

Iron core/shell nanoparticles as magnetic drug carriers: possible interactions with the vascular compartment

(2011) Inge K Herrmann et al.   Nanomedicine

Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles

(2011) Khaled Greish et al.   Nanotoxicology

Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials

(2011) Feng Zhao et al.   Small

Platelets and Primary Haemostasis

(2011) Kenneth J. Clemetson   THROMBOSIS RESEARCH

The Role of Particle Geometry and Mechanics in the Biological Domain

(2011) James P. Best et al.   Advanced Healthcare Materials

Rapid Uptake of Gold Nanorods by Primary Human Blood Phagocytes and Immunomodulatory Effects of Surface Chemistry

(2010) Matthias Bartneck et al.   ACS Nano

Close Encounters of the Small Kind: Adverse Effects of Man-Made Materials Interfacing with the Nano-Cosmos of Biological Systems

(2010) Anna A. Shvedova et al.   Annual Review of Pharmacology and Toxicology

Crystallization behavior of poly(ε-caprolactone)/layered double hydroxide nanocomposites

(2010) Zhe Yang et al.   JOURNAL OF APPLIED POLYMER SCIENCE

Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery (review)

(2010) Ryan B. Huang et al.   MOLECULAR MEMBRANE BIOLOGY

Nanomaterial cytotoxicity is composition, size, and cell type dependent

(2010) Syed K Sohaebuddin et al.   Particle and Fibre Toxicology

Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction

(2010) Denise N. Johnson-Lyles et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Cationic Poly(amidoamine) Dendrimer Induces Lysosomal Apoptotic Pathway at Therapeutically Relevant Concentrations

(2009) Thommey P. Thomas et al.   BIOMACROMOLECULES

Procoagulant Behavior and Platelet Microparticle Generation on Nanoporous Alumina

(2009) Natalia Ferraz et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

The role of monocytes in thrombotic disorders

(2009) Gregory Lip et al.   THROMBOSIS AND HAEMOSTASIS

Role of the platelet chemokine platelet factor 4 (PF4) in hemostasis and thrombosis

(2009) M. Anna Kowalska et al.   THROMBOSIS RESEARCH

The Receptor-Mediated Endocytosis of Nonspherical Particles

(2008) P. Decuzzi et al.   BIOPHYSICAL JOURNAL

Comparative genotoxicity of cobalt nanoparticles and ions on human peripheral leukocytes in vitro

(2008) R. Colognato et al.   MUTAGENESIS

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA