Implementation of alternative test strategies for the safety assessment of engineered nanomaterials

Systems toxicology

(2014) Thomas HArtung   ALTEX-Alternatives to Animal Experimentation

Perspectives on validation of high-throughput assays supporting 21st century toxicity testing

(2014) Richard Judson   ALTEX-Alternatives to Animal Experimentation

Surface Charge and Cellular Processing of Covalently Functionalized Multiwall Carbon Nanotubes Determine Pulmonary Toxicity

(2013) Ruibin Li et al.   ACS Nano

Nano-SAR Development for Bioactivity of Nanoparticles with Considerations of Decision Boundaries

(2013) Rong Liu et al.   Small

Use of Metal Oxide Nanoparticle Band Gap To Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation

(2012) Haiyuan Zhang et al.   ACS Nano

Toxicity profiling of engineered nanomaterials via multivariate dose-response surface modeling

(2012) Trina Patel et al.   Annals of Applied Statistics

Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management

(2012) Robert Kavlock et al.   CHEMICAL RESEARCH IN TOXICOLOGY

TOX 21: New Dimensions of Toxicity Testing

(2012) Charles W. Schmidt   ENVIRONMENTAL HEALTH PERSPECTIVES

Multi-walled carbon nanotubes: sampling criteria and aerosol characterization

(2012) Bean T. Chen et al.   INHALATION TOXICOLOGY

Development of risk-based nanomaterial groups for occupational exposure control

(2012) E. D. Kuempel et al.   JOURNAL OF NANOPARTICLE RESEARCH

Pluronic F108 Coating Decreases the Lung Fibrosis Potential of Multiwall Carbon Nanotubes by Reducing Lysosomal Injury

(2012) Xiang Wang et al.   NANO LETTERS

Acute pulmonary dose–responses to inhaled multi-walled carbon nanotubes

(2012) Dale W. Porter et al.   Nanotoxicology

Implementation of a Multidisciplinary Approach to Solve Complex Nano EHS Problems by the UC Center for the Environmental Implications of Nanotechnology

(2012) Tian Xia et al.   Small

Incorporating Biological, Chemical, and Toxicological Knowledge Into Predictive Models of Toxicity

(2012) David J. Dix et al.   TOXICOLOGICAL SCIENCES

A Comprehensive Statistical Analysis of Predicting In Vivo Hazard Using High-Throughput In Vitro Screening

(2012) Russell S. Thomas et al.   TOXICOLOGICAL SCIENCES

Long, Needle-like Carbon Nanotubes and Asbestos Activate the NLRP3 Inflammasome through a Similar Mechanism

(2011) Jaana Palomäki et al.   ACS Nano

Use of a High-Throughput Screening Approach Coupled with In Vivo Zebrafish Embryo Screening To Develop Hazard Ranking for Engineered Nanomaterials

(2011) Saji George et al.   ACS Nano

Dispersal State of Multiwalled Carbon Nanotubes Elicits Profibrogenic Cellular Responses That Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung

(2011) Xiang Wang et al.   ACS Nano

Informing Selection of Nanomaterial Concentrations for ToxCast in Vitro Testing Based on Occupational Exposure Potential

(2011) Sumit Gangwal et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Nanotoxicology: in Vitro–in Vivo Dosimetry

(2011) Günter Oberdörster   ENVIRONMENTAL HEALTH PERSPECTIVES

Self-Organizing Map Analysis of Toxicity-Related Cell Signaling Pathways for Metal and Metal Oxide Nanoparticles

(2011) Robert Rallo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Role of Fe Doping in Tuning the Band Gap of TiO2for the Photo-Oxidation-Induced Cytotoxicity Paradigm

(2011) Saji George et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-walled carbon nanotube-induced mitotic disruption

(2011) L.M. Sargent et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

No time to lose—high throughput screening to assess nanomaterial safety

(2011) R. Damoiseaux et al.   Nanoscale

Predictive models for nanotoxicology: Current challenges and future opportunities

(2011) Katherine A. Clark et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Classification NanoSAR Development for Cytotoxicity of Metal Oxide Nanoparticles

(2011) Rong Liu et al.   Small

Use of a Rapid Cytotoxicity Screening Approach To Engineer a Safer Zinc Oxide Nanoparticle through Iron Doping

(2010) Saji George et al.   ACS Nano

Quantitative Techniques for Assessing and Controlling the Dispersion and Biological Effects of Multiwalled Carbon Nanotubes in Mammalian Tissue Culture Cells

(2010) Xiang Wang et al.   ACS Nano

Concept of Assessing Nanoparticle Hazards Considering Nanoparticle Dosemetric and Chemical/Biological Response Metrics

(2010) Erik K. Rushton et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Biocompatible Nanoscale Dispersion of Single-Walled Carbon Nanotubes Minimizes in vivo Pulmonary Toxicity

(2010) Gökhan M. Mutlu et al.   NANO LETTERS

A critical review of the biological mechanisms underlying thein vivoandin vitrotoxicity of carbon nanotubes: The contribution of physico-chemical characteristics

(2010) Helinor J. Johnston et al.   Nanotoxicology

A theoretical framework for predicting the oxidative stress potential of oxide nanoparticles

(2010) Enrico Burello et al.   Nanotoxicology

Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity

(2010) Raymond F Hamilton et al.   Particle and Fibre Toxicology

Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

(2010) Ken Donaldson et al.   Particle and Fibre Toxicology

Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes

(2010) Robert R Mercer et al.   Particle and Fibre Toxicology

A Predictive Toxicological Paradigm for the Safety Assessment of Nanomaterials

(2009) Huan Meng et al.   ACS Nano

Potential Health Impact of Nanoparticles

(2009) Tian Xia et al.   Annual Review of Public Health

In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project

(2009) Richard S. Judson et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology

(2009) G. Oberdörster   JOURNAL OF INTERNAL MEDICINE

Toxicology for the twenty-first century

(2009) Thomas Hartung   NATURE

Inhaled carbon nanotubes reach the subpleural tissue in mice

(2009) Jessica P. Ryman-Rasmussen et al.   Nature Nanotechnology

Putting Chemicals on a Path To Better Risk Assessment

(2009) E. Stokstad   SCIENCE

Toward the Development of “Nano-QSARs”: Advances and Challenges

(2009) Tomasz Puzyn et al.   Small

Toxicity Testing in the 21st Century: A View from the Chemical Industry

(2009) James S. Bus et al.   TOXICOLOGICAL SCIENCES

Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes

(2009) Dale W. Porter et al.   TOXICOLOGY

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis

(2008) A. A. Shvedova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Structural Defects Play a Major Role in the Acute Lung Toxicity of Multiwall Carbon Nanotubes: Toxicological Aspects

(2008) Julie Muller et al.   CHEMICAL RESEARCH IN TOXICOLOGY

History and Evolution of Control Banding: A Review

(2008) David M. Zalk et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE

Progress towards monodisperse single-walled carbon nanotubes

(2008) Mark C. Hersam   Nature Nanotechnology

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology

Transforming Environmental Health Protection

(2008) Francis S. Collins et al.   SCIENCE

Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model

(2007) R. R. Mercer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY