Cationic liposomes induce cell necrosis through lysosomal dysfunction and late-stage autophagic flux inhibition

Codelivery of salinomycin and chloroquine by liposomes enables synergistic antitumor activity in vitro

(2016) Fangyuan Xie et al.   Nanomedicine

Cationic nanocarriers induce cell necrosis through impairment of Na+/K+-ATPase and cause subsequent inflammatory response

(2015) Xiawei Wei et al.   CELL RESEARCH

CD20 Antibody-Conjugated Immunoliposomes for Targeted Chemotherapy of Melanoma Cancer Initiating Cells

(2015) Hao Song et al.   Journal of Biomedical Nanotechnology

Co-delivery of doxorubicin and PEGylated C16-ceramide by nanoliposomes for enhanced therapy against multidrug resistance

(2015) Xiao Su et al.   Nanomedicine

Liposomal siRNA nanocarriers for cancer therapy

(2014) Bulent Ozpolat et al.   ADVANCED DRUG DELIVERY REVIEWS

Autophagy: An emerging target for cancer therapy

(2014) Maria Høyer-Hansen et al.   Autophagy

Inhibition of autophagy enhances the anticancer activity of silver nanoparticles

(2014) Jun Lin et al.   Autophagy

Overexpression of UCP1 in tobacco induces mitochondrial biogenesis and amplifies a broad stress response

(2014) Pedro Barreto et al.   BMC PLANT BIOLOGY

Amine-Containing Molecules and the Induction of an Expanded Lysosomal Volume Phenotype: A Structure–Activity Relationship Study

(2014) Randall Logan et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Autophagy inhibition strategy for advanced nanomedicine

(2014) Lin Mei et al.   Nanomedicine

Why should autophagic flux be assessed?

(2013) Xiao-jie Zhang et al.   ACTA PHARMACOLOGICA SINICA

Autophagy and formation of tubulovesicular autophagosomes provide a barrier against nonviral gene delivery

(2013) Rebecca Roberts et al.   Autophagy

Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance

(2013) Wen Yue et al.   Autophagy

Inhibition of hepatocellular carcinoma growth using immunoliposomes for co-delivery of adriamycin and ribonucleotide reductase M2 siRNA

(2013) Jie Gao et al.   BIOMATERIALS

Accelerating the clearance of mutant huntingtin protein aggregates through autophagy induction by europium hydroxide nanorods

(2013) Peng-Fei Wei et al.   BIOMATERIALS

Oxidative stress response elicited by mitochondrial dysfunction: Implication in the pathophysiology of aging

(2013) Chih-Hao Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1

(2012) M. Paulina Ordonez et al.   HUMAN MOLECULAR GENETICS

Rhomboid Protease PARL Mediates the Mitochondrial Membrane Potential Loss-induced Cleavage of PGAM5

(2012) Shiori Sekine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

(2011) Xiaowei Ma et al.   ACS Nano

Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

(2011) Hong-Min Ni et al.   Autophagy

The selective growth inhibition of oral cancer by iron core-gold shell nanoparticles through mitochondria-mediated autophagy

(2011) Ya-Na Wu et al.   BIOMATERIALS

Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies

(2011) W. Alduaij et al.   BLOOD

Mitophagy Plays an Essential Role in Reducing Mitochondrial Production of Reactive Oxygen Species and Mutation of Mitochondrial DNA by Maintaining Mitochondrial Quantity and Quality in Yeast

(2011) Yusuke Kurihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy as a target for anticancer therapy

(2011) Filip Janku et al.   Nature Reviews Clinical Oncology

Human Macrophages Infected with a High Burden of ESAT-6-Expressing M. tuberculosis Undergo Caspase-1- and Cathepsin B-Independent Necrosis

(2011) Amanda Welin et al.   PLoS One

Oxidative stress and toxicity of gold nanoparticles in Mytilus edulis

(2010) Sara Tedesco et al.   AQUATIC TOXICOLOGY

Induction of genuine autophagy by cationic lipids in mammalian cells

(2010) Na Man et al.   Autophagy

The molecular mechanism of mitochondria autophagy in yeast

(2010) Tomotake Kanki et al.   MOLECULAR MICROBIOLOGY

C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy

(2010) Pengfei Wei et al.   NANOTECHNOLOGY

Nanomaterial cytotoxicity is composition, size, and cell type dependent

(2010) Syed K Sohaebuddin et al.   Particle and Fibre Toxicology

Lysosomal Storage Disease: Revealing Lysosomal Function and Physiology

(2010) Emma J. Parkinson-Lawrence et al.   PHYSIOLOGY

Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction

(2010) Denise N. Johnson-Lyles et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Methodological considerations for assessing autophagy modulators: A study with calcium phosphate precipitates

(2009) Sovan Sarkar et al.   Autophagy

Autophagy-mediated chemosensitization in cancer cells by fullerene C60 nanocrystal

(2009) Qiang Zhang et al.   Autophagy

Lyophilized HER2-specific PEGylated immunoliposomes for active siRNA gene silencing

(2009) Jie Gao et al.   BIOMATERIALS

Live Imaging of Neuronal Degradation by Microglia Reveals a Role for v0-ATPase a1 in Phagosomal Fusion In Vivo

(2008) Francesca Peri et al.   CELL

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE