DNA damage response and repair pathway modulation by non-histone protein methylation: implications in neurodegeneration
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
DNA damage response and repair pathway modulation by non-histone protein methylation: implications in neurodegeneration
Authors
Keywords
-
Journal
Journal of Cell Communication and Signaling
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-11-20
DOI
10.1007/s12079-019-00538-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- PTEN arginine methylation by PRMT6 suppresses PI3K–AKT signaling and modulates pre-mRNA splicing
- (2019) Jiawen Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects
- (2019) Joy Mitra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions
- (2019) Jianping Guo et al. NATURE CELL BIOLOGY
- SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis
- (2019) Guihua Wang et al. NATURE CELL BIOLOGY
- PRMT7 methylates eukaryotic translation initiation factor 2α and regulates its role in stress granule formation
- (2019) Nasim Haghandish et al. MOLECULAR BIOLOGY OF THE CELL
- Methylation of C/EBPα by PRMT1 inhibits its tumor suppressive function in breast cancer
- (2019) Li-ming Liu et al. CANCER RESEARCH
- UBAP2L arginine methylation by PRMT1 modulates stress granule assembly
- (2019) Chuyu Huang et al. CELL DEATH AND DIFFERENTIATION
- Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis
- (2019) Erika N Guerrero et al. HUMAN MOLECULAR GENETICS
- SETD1A methyltransferase is physically and functionally linked to the DNA damage repair protein RAD18
- (2019) Manal Alsulami et al. MOLECULAR & CELLULAR PROTEOMICS
- Cellular consequences of arginine methylation
- (2019) Benjamin M. Lorton et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Preserving genome integrity and function: the DNA damage response and histone modifications
- (2019) Jae Jin Kim et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Arginine methylation of the DDX 5 helicase RGG / RG motif by PRMT 5 regulates resolution of RNA:DNA hybrids
- (2019) Sofiane Y Mersaoui et al. EMBO JOURNAL
- Mechanisms of Mitochondrial DNA Repair in Mammals
- (2018) L. A. Zinovkina BIOCHEMISTRY-MOSCOW
- SOD1 in Amyotrophic Lateral Sclerosis: “Ambivalent” Behavior Connected to the Disease
- (2018) Orietta Pansarasa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations
- (2018) Liang Chen et al. MOLECULAR CELL
- Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization
- (2018) Lifeng Huang et al. NUCLEIC ACIDS RESEARCH
- PRMT5-mediated arginine methylation of TDP1 for the repair of topoisomerase I covalent complexes
- (2018) Ishita Rehman et al. NUCLEIC ACIDS RESEARCH
- A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy
- (2018) Maneka Chitiprolu et al. Nature Communications
- R-Loops in Motor Neuron Diseases
- (2018) Martina G. L. Perego et al. MOLECULAR NEUROBIOLOGY
- Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis
- (2018) Haibo Wang et al. Nature Communications
- Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase
- (2018) Jędrzej M. Małecki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Methylation of UHRF1 by SET7 is essential for DNA double-strand break repair
- (2018) Ja Young Hahm et al. NUCLEIC ACIDS RESEARCH
- Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability
- (2018) Sonia Silva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The story of protein arginine methylation: characterization, regulation, and function
- (2017) Chao Peng et al. Expert Review of Proteomics
- Human METTL12 is a mitochondrial methyltransferase that modifies citrate synthase
- (2017) Virginie F. Rhein et al. FEBS LETTERS
- DNA damage responses in central nervous system and age-associated neurodegeneration
- (2017) Muralidhar L. Hegde et al. MECHANISMS OF AGEING AND DEVELOPMENT
- PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination
- (2017) Thomas L. Clarke et al. MOLECULAR CELL
- Histone methylation and the DNA damage response
- (2017) Fade Gong et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells
- (2017) Mattia Poletto et al. NUCLEIC ACIDS RESEARCH
- New factors in mammalian DNA repair—the chromatin connection
- (2017) G Raschellà et al. ONCOGENE
- The tale of a tail: histone H4 acetylation and the repair of DNA breaks
- (2017) Surbhi Dhar et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Systematic Proteomic Analysis of Protein Methylation in Prokaryotes and Eukaryotes Revealed Distinct Substrate Specificity
- (2017) Min Zhang et al. PROTEOMICS
- Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
- (2016) Steve Horvath et al. Aging-US
- Biochemistry and regulation of the protein arginine methyltransferases (PRMTs)
- (2016) Yalemi Morales et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Protein lysine methylation by seven- -strand methyltransferases
- (2016) P. O. Falnes et al. BIOCHEMICAL JOURNAL
- DNA damage tolerance by recombination: Molecular pathways and DNA structures
- (2016) Dana Branzei et al. DNA REPAIR
- Epigenome Maintenance in Response to DNA Damage
- (2016) Juliette Dabin et al. MOLECULAR CELL
- 53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms
- (2016) Raquel Cuella-Martin et al. MOLECULAR CELL
- XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia
- (2016) Nicolas C. Hoch et al. NATURE
- Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells
- (2016) Sara C. Larsen et al. Science Signaling
- Repair Pathway Choices and Consequences at the Double-Strand Break
- (2016) Raphael Ceccaldi et al. TRENDS IN CELL BIOLOGY
- G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression
- (2016) Xi Zhang et al. Nature Communications
- Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells
- (2016) Sara C. Larsen et al. Science Signaling
- Opposite effects of two estrogen receptors on tau phosphorylation through disparate effects on the miR-218/PTPA pathway
- (2015) Yan-Si Xiong et al. AGING CELL
- Mutations in PNKP Cause Recessive Ataxia with Oculomotor Apraxia Type 4
- (2015) Jose Bras et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Chromatin dynamics after DNA damage: The legacy of the access–repair–restore model
- (2015) Sophie E. Polo et al. DNA REPAIR
- Spatiotemporal regulation of posttranslational modifications in the DNA damage response
- (2015) N. P. Dantuma et al. EMBO JOURNAL
- SET7/9 regulates cancer cell proliferation by influencing β-catenin stability
- (2015) Changchun Shen et al. FASEB JOURNAL
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
- (2015) Meaghan Morris et al. NATURE NEUROSCIENCE
- Comprehensive identification of arginine methylation in primary T cells reveals regulatory roles in cell signalling
- (2015) Vincent Geoghegan et al. Nature Communications
- Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis
- (2015) Dong Hu et al. Nature Communications
- Arginine methylation of hnRNPUL1 regulates interaction with NBS1 and recruitment to sites of DNA damage
- (2015) Gayathri Gurunathan et al. Scientific Reports
- Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi–Goutières syndrome
- (2015) Yoong Wearn Lim et al. eLife
- Regulation of the DNA damage response by ubiquitin conjugation
- (2015) Kerstin Brinkmann et al. Frontiers in Genetics
- The Oncogenic Polycomb Histone Methyltransferase EZH2Methylates Lysine 120 on Histone H2B and Competes Ubiquitination
- (2015) Masaharu Kogure et al. NEOPLASIA
- Mechanisms of transcriptional dysregulation in repeat expansion disorders
- (2014) Matthias Groh et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Molecular basis for substrate recognition by lysine methyltransferases and demethylases
- (2014) Paul A. Del Rizzo et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation
- (2014) Ryuji Hamamoto et al. CANCER LETTERS
- Human METTL20 Is a Mitochondrial Lysine Methyltransferase That Targets the β Subunit of Electron Transfer Flavoprotein (ETFβ) and Modulates Its Activity
- (2014) Jędrzej Małecki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Insights into Estrogen Receptor α Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation
- (2014) Yuanyuan Jiang et al. JOURNAL OF MOLECULAR BIOLOGY
- Arginine Methylation Facilitates the Recruitment of TOP3B to Chromatin to Prevent R Loop Accumulation
- (2014) Yanzhong Yang et al. MOLECULAR CELL
- C9orf72 nucleotide repeat structures initiate molecular cascades of disease
- (2014) Aaron R. Haeusler et al. NATURE
- SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
- (2014) Pawel K. Mazur et al. NATURE
- Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor
- (2014) S. M. Carr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcription-Associated R-Loop Formation across the Human FMR1 CGG-Repeat Region
- (2014) Erick W. Loomis et al. PLoS Genetics
- The Histone Methyltransferase SMYD2 Methylates PARP1 and Promotes Poly(ADP-ribosyl)ation Activity in Cancer Cells
- (2014) Lianhua Piao et al. NEOPLASIA
- Identification and Characterization of a Novel Human Methyltransferase Modulating Hsp70 Protein Function through Lysine Methylation
- (2013) Magnus E. Jakobsson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PRKDC mutations in a SCID patient with profound neurological abnormalities
- (2013) Lisa Woodbine et al. JOURNAL OF CLINICAL INVESTIGATION
- Immunoaffinity Enrichment and Mass Spectrometry Analysis of Protein Methylation
- (2013) Ailan Guo et al. MOLECULAR & CELLULAR PROTEOMICS
- A Method for Systematic Mapping of Protein Lysine Methylation Identifies Functions for HP1β in DNA Damage Response
- (2013) Huadong Liu et al. MOLECULAR CELL
- Regulation of DNA Damage Responses by Ubiquitin and SUMO
- (2013) Stephen P. Jackson et al. MOLECULAR CELL
- Maintaining genome stability in the nervous system
- (2013) Peter J McKinnon NATURE NEUROSCIENCE
- A mediator methylation mystery: JMJD1C demethylates MDC1 to regulate DNA repair
- (2013) Jian Lu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1–mediated chromatin response to DNA breaks
- (2013) Sugiko Watanabe et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability
- (2013) D. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Discovery of Histone Demethylases
- (2013) Y. G. Shi et al. Cold Spring Harbor Perspectives in Biology
- SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress
- (2013) I. Kassner et al. Open Biology
- The protein arginine deiminases: Structure, function, inhibition, and disease
- (2012) Kevin L. Bicker et al. BIOPOLYMERS
- Histone Lysine Methyltransferase SETD8 Promotes Carcinogenesis by Deregulating PCNA Expression
- (2012) M. Takawa et al. CANCER RESEARCH
- Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed Genes
- (2012) Amaya Alzu et al. CELL
- Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death
- (2012) Qi Xie et al. EMBO REPORTS
- R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants
- (2012) P. C. Stirling et al. GENES & DEVELOPMENT
- Dysregulation of Mitochondrial Calcium Signaling and Superoxide Flashes Cause Mitochondrial Genomic DNA Damage in Huntington Disease
- (2012) Jiu-Qiang Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair
- (2012) Sophie E. Polo et al. MOLECULAR CELL
- EZH2 Generates a Methyl Degron that Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex
- (2012) Ji Min Lee et al. MOLECULAR CELL
- Prime, Repair, Restore: The Active Role of Chromatin in the DNA Damage Response
- (2012) Gaston Soria et al. MOLECULAR CELL
- Regulation of KLF4 Turnover Reveals an Unexpected Tissue-Specific Role of pVHL in Tumorigenesis
- (2012) Armin M. Gamper et al. MOLECULAR CELL
- R Loops: From Transcription Byproducts to Threats to Genome Stability
- (2012) Andrés Aguilera et al. MOLECULAR CELL
- Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation
- (2012) Scott B Rothbart et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Effect of PRMT1-Mediated Arginine Methylation on the Subcellular Localization, Stress Granules, and Detergent-Insoluble Aggregates of FUS/TLS
- (2012) Atsushi Yamaguchi et al. PLoS One
- Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B
- (2012) Hyun-Soo Cho et al. Nature Communications
- Dual modification of Alzheimer’s disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach
- (2011) Stefani N. Thomas et al. ACTA NEUROPATHOLOGICA
- The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates
- (2011) Uttiya Basu et al. CELL
- Roles of protein arginine methylation in DNA damage signaling pathways
- (2011) Young-Ho Lee et al. CELL CYCLE
- The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation
- (2011) Zhenbao Yu et al. CELL RESEARCH
- Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
- (2011) S. E. Polo et al. GENES & DEVELOPMENT
- Accelerated Age-Related Cognitive Decline and Neurodegeneration, Caused by Deficient DNA Repair
- (2011) N. Z. Borgesius et al. JOURNAL OF NEUROSCIENCE
- Methylation-mediated regulation of E2F1 in DNA damage-induced cell death
- (2011) Qi Xie et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome Instability
- (2011) Lamia Wahba et al. MOLECULAR CELL
- Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination
- (2011) Konstantina Skourti-Stathaki et al. MOLECULAR CELL
- More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
- (2011) Jiri Lukas et al. NATURE CELL BIOLOGY
- A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage
- (2011) Wei He et al. NUCLEIC ACIDS RESEARCH
- PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse
- (2011) P. V. Hornbeck et al. NUCLEIC ACIDS RESEARCH
- Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1)
- (2011) Xiangyu Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Overview of DNA Repair in Amyotrophic Lateral Sclerosis
- (2011) Fabio Coppedè TheScientificWorldJOURNAL
- Methylation of the Retinoblastoma Tumor Suppressor by SMYD2
- (2010) Louis A. Saddic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53
- (2010) Jing Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysine Methylation Regulates E2F1-Induced Cell Death
- (2010) Haroula Kontaki et al. MOLECULAR CELL
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding
- (2010) Zhigang Guo et al. Nature Chemical Biology
- Methylation of the Tumor Suppressor Protein, BRCA1, Influences Its Transcriptional Cofactor Function
- (2010) Irene Guendel et al. PLoS One
- Mutation update for theCSB/ERCC6andCSA/ERCC8genes involved in Cockayne syndrome
- (2009) V. Laugel et al. HUMAN MUTATION
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- DNA repair deficiency and neurological disease
- (2009) Peter J. McKinnon NATURE REVIEWS NEUROSCIENCE
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- Mitochondrial DNA, base excision repair and neurodegeneration
- (2008) Nadja C. de Souza-Pinto et al. DNA REPAIR
- Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase
- (2008) Krithika Subramanian et al. MOLECULAR CELL
- Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt
- (2008) Kazuyuki Yamagata et al. MOLECULAR CELL
- Regulation of DNA repair throughout the cell cycle
- (2008) Dana Branzei et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More