Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells

Protein oxidation and peroxidation

(2016) M. J. Davies   BIOCHEMICAL JOURNAL

p53 coordinates base excision repair to prevent genomic instability

(2016) Mattia Poletto et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial proteases and protein quality control in ageing and longevity

(2015) Marie-Paule Hamon et al.   AGEING RESEARCH REVIEWS

Mechanisms of ATM Activation

(2015) Tanya T. Paull   Annual Review of Biochemistry

Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway

(2015) Wen-Cheng Chou et al.   CARCINOGENESIS

Reactive Oxygen Species (ROS)-Activated ATM-Dependent Phosphorylation of Cytoplasmic Substrates Identified by Large-Scale Phosphoproteomics Screen

(2015) Sergei V. Kozlov et al.   MOLECULAR & CELLULAR PROTEOMICS

Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability

(2015) Enni Markkanen et al.   NUCLEIC ACIDS RESEARCH

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

ATM prevents DSB formation by coordinating SSB repair and cell cycle progression

(2015) Svetlana V. Khoronenkova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quality Control and Infiltration of Translation by Amino Acids Outside of the Genetic Code

(2014) Tammy Bullwinkle et al.   Annual Review of Genetics

DNA Damage Response Genes and the Development of Cancer Metastasis

(2014) Constantinos G. Broustas et al.   RADIATION RESEARCH

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

(2013) M. Ambrose et al.   BLOOD

Base excision repair in the mammalian brain: Implication for age related neurodegeneration

(2013) Peter Sykora et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ARF induction in response to DNA strand breaks is regulated by PARP1

(2013) Giulia Orlando et al.   NUCLEIC ACIDS RESEARCH

Mammalian Base Excision Repair: the Forgotten Archangel

(2013) Grigory L. Dianov et al.   NUCLEIC ACIDS RESEARCH

Translational Repression and eIF4A2 Activity Are Critical for MicroRNA-Mediated Gene Regulation

(2013) H. A. Meijer et al.   SCIENCE

The proteasome and the degradation of oxidized proteins: Part II – protein oxidation and proteasomal degradation

(2013) Tobias Jung et al.   Redox Biology

Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks

(2012) Adva Levy-Barda et al.   CELL CYCLE

Histone carbonylation occurs in proliferating cells

(2012) José Luis García-Giménez et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of Double-stranded RNA-activated Protein Kinase (PKR) by Interferon-stimulated Gene 15 (ISG15) Modification Down-regulates Protein Translation

(2012) Fumihiko Okumura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reducing Mitochondrial ROS Improves Disease-related Pathology in a Mouse Model of Ataxia-telangiectasia

(2012) Anthony D D'Souza et al.   MOLECULAR THERAPY

Mitochondrial dysfunction in ataxia-telangiectasia

(2011) Y. A. Valentin-Vega et al.   BLOOD

Oxidative Stress-Mediated Regulation of Proteasome Complexes

(2011) Charity T. Aiken et al.   MOLECULAR & CELLULAR PROTEOMICS

A Novel Role for ATM in Regulating Proteasome-Mediated Protein Degradation through Suppression of the ISG15 Conjugation Pathway

(2011) Laurence M. Wood et al.   PLoS One

The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes

(2010) Andrew M. Pickering et al.   BIOCHEMICAL JOURNAL

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)

(2009) A Arlt et al.   ONCOGENE