The Signaling Pathways, and Therapeutic Targets of Antiviral Agents: Focusing on the Antiviral Approaches and Clinical Perspectives of Anthocyanins in the Management of Viral Diseases

The interplay between viruses and TRIM family proteins

(2019) Ramisha Khan et al.   REVIEWS IN MEDICAL VIROLOGY

Differential accumulation of pelargonidin glycosides in petals at three different developmental stages of the orange-flowered gentian (Gentiana lutea L. var. aurantiaca)

(2019) Gianfranco Diretto et al.   PLoS One

Ultrasound as a Rapid and Low-Cost Extraction Procedure to Obtain Anthocyanin-Based Colorants from Prunus spinosa L. Fruit Epicarp: Comparative Study with Conventional Heat-Based Extraction

(2019) Maria G. Leichtweis et al.   MOLECULES

Pomegranate Fruit and Juice (cv. Mollar), Rich in Ellagitannins and Anthocyanins, Also Provide a Significant Content of a Wide Range of Proanthocyanidins

(2019) Huertas M. Díaz-Mula et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Comparative Study on the Chemical Structure and In Vitro Antiproliferative Activity of Anthocyanins in Purple Root Tubers and Leaves of Sweet Potato (Ipomoea batatas)

(2019) Vijayakumar R. Vishnu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Anthocyanins and metabolites from purple rice inhibit IL-1β-induced matrix metalloproteinases expression in human articular chondrocytes through the NF-κB and ERK/MAPK pathway

(2019) Tunchanok Wongwichai et al.   BIOMEDICINE & PHARMACOTHERAPY

Nanocrystallization of Anthocyanin Extract from Red-Fleshed Apple ′QN-5′ Improved Its Antioxidant Effect through Enhanced Stability and Activity under Stressful Conditions

(2019) Xiang Zhang et al.   MOLECULES

Nanoemulsion and Nanoliposome Based Strategies for Improving Anthocyanin Stability and Bioavailability

(2019) Bing-Huei Chen et al.   Nutrients

Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties

(2019) Sherif T. S. Hassan et al.   MOLECULES

Black rice anthocyanins embedded in self-assembled chitosan/chondroitin sulfate nanoparticles enhance apoptosis in HCT-116 cells

(2019) Tisong Liang et al.   FOOD CHEMISTRY

Formation and stability of anthocyanins-loaded nanocomplexes prepared with chitosan hydrochloride and carboxymethyl chitosan

(2018) Jiao Ge et al.   FOOD HYDROCOLLOIDS

Roselle Anthocyanins: Antioxidant Properties and Stability to Heat and pH

(2018) Hai-Yao Wu et al.   MOLECULES

Nanocomplexes composed of chitosan derivatives and β-Lactoglobulin as a carrier for anthocyanins: Preparation, stability and bioavailability in vitro

(2018) Jiao Ge et al.   FOOD RESEARCH INTERNATIONAL

Regular Consumption of Dark Chocolate Is Associated with Low Serum Concentrations of C-Reactive Protein in a Healthy Italian Population

(2018) Romina di Giuseppe et al.   JOURNAL OF NUTRITION

A Polyphenol Rich Extract from Solanum melongena L. DR2 Peel Exhibits Antioxidant Properties and Anti-Herpes Simplex Virus Type 1 Activity In Vitro

(2018) Antonella Di Sotto et al.   MOLECULES

Antiviral Activities of Mulberry (Morus alba) Juice and Seed against Influenza Viruses

(2018) Hyojin Kim et al.   Evidence-based Complementary and Alternative Medicine

Nanomedicine formulations for the delivery of antiviral drugs: a promising solution for the treatment of viral infections

(2017) David Lembo et al.   Expert Opinion on Drug Delivery

Loading of anthocyanins on chitosan nanoparticles influences anthocyanin degradation in gastrointestinal fluids and stability in a beverage

(2017) Bo He et al.   FOOD CHEMISTRY

Fabrication and characterization of biocompatible hybrid nanoparticles from spontaneous co-assembly of casein/gliadin and proanthocyanidin

(2017) Chengzhen Liu et al.   FOOD HYDROCOLLOIDS

The inhibitory performance of flavonoid cyanidin-3-sambubiocide against H274Y mutation in H1N1 influenza virus

(2017) S. Kannan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Berries as a potential anti-influenza factor – A review

(2017) Anna Gramza-Michałowska et al.   Journal of Functional Foods

Formulation and Characterization of Anthocyanins-Loaded Nanoparticles

(2017) Danay Dupeyrón et al.   Current Drug Delivery

Identification and Analysis of Novel Inhibitors against NS3 Helicase and NS5B RNA-Dependent RNA Polymerase from Hepatitis C Virus 1b (Con1)

(2017) Na Yang et al.   Frontiers in Microbiology

Antiviral Properties of the Natural Polyphenols Delphinidin and Epigallocatechin Gallate against the Flaviviruses West Nile Virus, Zika Virus, and Dengue Virus

(2017) Ángela Vázquez-Calvo et al.   Frontiers in Microbiology

Anthocyanins encapsulated by PLGA@PEG nanoparticles potentially improved its free radical scavenging capabilities via p38/JNK pathway against Aβ1–42-induced oxidative stress

(2017) Faiz Ul Amin et al.   JOURNAL OF NANOBIOTECHNOLOGY

Antiviral effects of black raspberry (Rubus coreanus) seed extract and its polyphenolic compounds on norovirus surrogates

(2016) Ji-Hye Lee et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Chemistry, Pharmacology and Health Benefits of Anthocyanins

(2016) Antonella Smeriglio et al.   PHYTOTHERAPY RESEARCH

Antiviral Effects of Black Raspberry (Rubus coreanus) Seed and Its Gallic Acid against Influenza Virus Infection

(2016) Ji-Hye Lee et al.   Viruses-Basel

Polyphenolic compounds, anthocyanins and antioxidant activity of nineteen pomegranate fruits: A rich source of bioactive compounds

(2016) Pilar Legua et al.   Journal of Functional Foods

Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial

(2016) Evelin Tiralongo et al.   Nutrients

Discovery of novel targets for antivirals: learning from flies

(2016) Nelson Martins et al.   Current Opinion in Virology

Role of Marine Natural Products in the Genesis of Antiviral Agents

(2015) Vedanjali Gogineni et al.   CHEMICAL REVIEWS

Analysis and characterisation of phytochemicals in mulberry (Morus alba L.) fruits grown in Vojvodina, North Serbia

(2015) Maja M. Natić et al.   FOOD CHEMISTRY

A review: Using nanoparticles to enhance absorption and bioavailability of phenolic phytochemicals

(2015) Zheng Li et al.   FOOD HYDROCOLLOIDS

Antiviral effects of grape seed extract against feline calicivirus, murine norovirus, and hepatitis A virus in model food systems and under gastric conditions

(2015) Snehal S. Joshi et al.   FOOD MICROBIOLOGY

Biopolymer nanoparticles as potential delivery systems for anthocyanins: Fabrication and properties

(2015) Izlia J. Arroyo-Maya et al.   FOOD RESEARCH INTERNATIONAL

Anti-influenza virus effects of cocoa

(2015) Masanori Kamei et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action

(2015) Noémie Calland et al.   JOURNAL OF VIROLOGY

Anthocyanin composition of different wild and cultivated berry species

(2015) Robert Veberic et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Protein/peptide-based entry/fusion inhibitors as anti-HIV therapies: challenges and future direction

(2015) Miral Fumakia et al.   REVIEWS IN MEDICAL VIROLOGY

Current treatment of hepatitis B virus infections

(2015) Erik De Clercq   REVIEWS IN MEDICAL VIROLOGY

RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity

(2015) Fernando Valiente-Echeverría et al.   REVIEWS IN MEDICAL VIROLOGY

Nanomedicine for Infectious Disease Applications: Innovation towards Broad-Spectrum Treatment of Viral Infections

(2015) Joshua A. Jackman et al.   Small

Dietary anthocyanins as a complementary medicinal approach for management of inflammatory bowel disease

(2015) Hamid Reza Sodagari et al.   Expert Review of Gastroenterology & Hepatology

Letermovir and inhibitors of the terminase complex: a promising new class of investigational antiviral drugs against human cytomegalovirus

(2015) Raymund Razonable et al.   Infection and Drug Resistance

Antiviral Activity of Solanum paniculatum Extract and Constituents

(2015) Ydia M. Valadares et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES

Substituent effects on the binding of natural product anthocyanidin inhibitors to influenza neuraminidase with mass spectrometry

(2014) Kavya Swaminathan et al.   ANALYTICA CHIMICA ACTA

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Bioavailability of anthocyanins

(2014) Jim Fang   DRUG METABOLISM REVIEWS

Current Status in the Therapy of Liver Diseases

(2014) Philipp Uhl et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reduction of adenovirus 36-induced obesity and inflammation by mulberry extract

(2014) Ha-Na Na et al.   MICROBIOLOGY AND IMMUNOLOGY

Anti-Hepatitis B Virus Effects of Dehydrocheilanthifoline from Corydalis saxicola

(2013) Fan-Li Zeng et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Binding of a natural anthocyanin inhibitor to influenza neuraminidase by mass spectrometry

(2013) Kavya Swaminathan et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Aronia melanocarpa and its components demonstrate antiviral activity against influenza viruses

(2013) Sehee Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-HBV active constituents from Piper longum

(2013) Zhi-Yong Jiang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry

(2013) Liang-Tzung Lin et al.   BMC MICROBIOLOGY

The Case for Anthocyanin Consumption to Promote Human Health: A Review

(2013) Elisa Pojer et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Antiviral Effects of Mulberry (Morus alba) Juice and Its Fractions on Foodborne Viral Surrogates

(2013) Ji-Hye Lee et al.   Foodborne Pathogens and Disease

A Plant Extract of Ribes nigrum folium Possesses Anti-Influenza Virus Activity In Vitro and In Vivo by Preventing Virus Entry to Host Cells

(2013) Christina Ehrhardt et al.   PLoS One

Inhibitory receptor molecules in chronic hepatitis B and C infections: novel targets for immunotherapy?

(2013) Mohamad S. Hakim et al.   REVIEWS IN MEDICAL VIROLOGY

Glycoprotein targeted therapeutics: a new era of anti-herpes simplex virus-1 therapeutics

(2013) Thessicar E. Antoine et al.   REVIEWS IN MEDICAL VIROLOGY

Homoisoflavonoids from Caesalpinia sappan Displaying Viral Neuraminidases Inhibition

(2012) Hyung Jae Jeong et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Xanthones from Polygala karensium inhibit neuraminidases from influenza A viruses

(2012) Trong Tuan Dao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of HIV-1 replication by a tricyclic coumarin GUT-70 in acutely and chronically infected cells

(2012) Eriko Kudo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antiviral Effects of Black Raspberry (Rubus coreanus) Juice on Foodborne Viral Surrogates

(2012) Mi Oh et al.   Foodborne Pathogens and Disease

Antiviral therapy: old and current issues

(2012) Guido Antonelli et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Hepatoprotective and antiviral properties of isochlorogenic acid A from Laggera alata against hepatitis B virus infection

(2012) Bing-Jie Hao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Dietary Supplementation with Lacto-Wolfberry Enhances the Immune Response and Reduces Pathogenesis to Influenza Infection in Mice

(2012) Zhihong Ren et al.   JOURNAL OF NUTRITION

Relationship between polyphenol content and anti-influenza viral effects of berries

(2012) Haruhito Sekizawa et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Anti-viral and anti-bacterial activities of an extract of blackcurrants (Ribes nigrum L.)

(2012) Kazufumi Ikuta et al.   MICROBIOLOGY AND IMMUNOLOGY

Zinc-finger Nuclease Editing of Human cxcr4 Promotes HIV-1 CD4+ T Cell Resistance and Enrichment

(2012) Jinyun Yuan et al.   MOLECULAR THERAPY

Houttuynoids A–E, Anti-Herpes Simplex Virus Active Flavonoids with Novel Skeletons from Houttuynia cordata

(2012) Shao-Dan Chen et al.   ORGANIC LETTERS

Hepatitis C Virus and Natural Compounds: A New Antiviral Approach?

(2012) Noémie Calland et al.   Viruses-Basel

Monoclonal Antibody-Based Candidate Therapeutics Against HIV Type 1

(2011) Weizao Chen et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Grape Seed Extract for Control of Human Enteric Viruses

(2011) Xiaowei Su et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses

(2011) Christian Krawitz et al.   BMC Complementary and Alternative Medicine

Chemokine control of West Nile virus infection

(2011) Jean K. Lim et al.   EXPERIMENTAL CELL RESEARCH

Zinc-Finger Nucleases for Somatic Gene Therapy: The Next Frontier

(2011) Shamim H. Rahman et al.   HUMAN GENE THERAPY

Resveratrol-Mediated Gamma Interferon Reduction Prevents Airway Inflammation and Airway Hyperresponsiveness in Respiratory Syncytial Virus-Infected Immunocompromised Mice

(2011) N. Zang et al.   JOURNAL OF VIROLOGY

Dietary anthocyanin-rich plants: Biochemical basis and recent progress in health benefits studies

(2011) Takanori Tsuda   MOLECULAR NUTRITION & FOOD RESEARCH

Antiviral effects of blackberry extract against herpes simplex virus type 1

(2011) Robert J. Danaher et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS

Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids

(2011) Berrin Özçelik et al.   PHARMACEUTICAL BIOLOGY

FlavoneC-glycosides from the Leaves ofLophatherum gracileand TheirIn VitroAntiviral Activity

(2011) Ying Wang et al.   PLANTA MEDICA

Lycium Barbarum Polysaccharides Reduce Neuronal Damage, Blood-Retinal Barrier Disruption and Oxidative Stress in Retinal Ischemia/Reperfusion Injury

(2011) Suk-Yee Li et al.   PLoS One

In-vitro antiviral activity of Solanum nigrum against Hepatitis C Virus

(2011) Tariq Javed et al.   Virology Journal

Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata

(2010) Trong Tuan Dao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hypersensitivity reactions to HIV therapy

(2010) Mas Chaponda et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Immune-modulating efficacy of a polyphenol-rich beverage on symptoms associated with the common cold: a double-blind, randomised, placebo-controlled, multi-centric clinical study

(2010) Katrin Schütz et al.   BRITISH JOURNAL OF NUTRITION

Bioactive Compounds in Cranberries and their Biological Properties

(2010) J. Côté et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Pharmacotherapy of respiratory syncytial virus infection

(2010) Robert C Welliver   CURRENT OPINION IN PHARMACOLOGY

Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1α

(2010) Maya Mouler Rechtman et al.   FEBS LETTERS

Anthocyanins composition and antioxidant activity of wild Lycium ruthenicum Murr. from Qinghai-Tibet Plateau

(2010) Jie Zheng et al.   FOOD CHEMISTRY

Expanded Highly Active Antiretroviral Therapy Coverage Among HIV-Positive Drug Users to Improve Individual and Public Health Outcomes

(2010) Julio S G Montaner et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2

(2010) K. Chono et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Palivizumab prophylaxis in ‘late preterm’ newborns

(2010) Marcello Lanari et al.   Journal of Maternal-Fetal & Neonatal Medicine

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

(2010) Nathalia Holt et al.   NATURE BIOTECHNOLOGY

Treatment of respiratory syncytial virus with palivizumab: a systematic review

(2010) Jia Hu et al.   World Journal of Pediatrics

Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen)

(2010) Weihuan Huang et al.   Chinese Medicine

When and how to use maraviroc in HIV-infected patients

(2009) Vincent Soriano et al.   AIDS

Anthocyanin supplementation improves serum LDL- and HDL-cholesterol concentrations associated with the inhibition of cholesteryl ester transfer protein in dyslipidemic subjects

(2009) Yu Qin et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Nonnucleoside Reverse Transcriptase Inhibitor Resistance and the Role of the Second-Generation Agents

(2009) Jessica Adams et al.   ANNALS OF PHARMACOTHERAPY

Pharmacogenetics of antiretrovirals

(2009) Valerio Tozzi   ANTIVIRAL RESEARCH

Entry inhibitors in the treatment of HIV-1 infection

(2009) John C. Tilton et al.   ANTIVIRAL RESEARCH

Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989–2009)

(2009) Marie-Pierre de Béthune   ANTIVIRAL RESEARCH

Pharmacokinetics and metabolism of the putative cancer chemopreventive agent cyanidin-3-glucoside in mice

(2009) Timothy H. Marczylo et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Etravirine: A second-generation nonnucleoside reverse transcriptase inhibitor (NNRTI) active against NNRTI-resistant strains of HIV

(2009) Daryl S. Schiller et al.   CLINICAL THERAPEUTICS

The antiviral activity of toll-like receptor 7 and 7/8 agonists

(2009) R.L. Miller et al.   DRUG NEWS & PERSPECTIVES

Silymarin Inhibits In Vitro T-Cell Proliferation and Cytokine Production in Hepatitis C Virus Infection

(2009) Chihiro Morishima et al.   GASTROENTEROLOGY

Anthocyanin content, antioxidant, anti-inflammatory and anticancer properties of blackberry and raspberry fruits

(2009) Camille S. Bowen-Forbes et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Anthocyanins, Antioxidative, and Antimicrobial Properties of American Cranberry (Vaccinium macrocarponAit.) and their Press Cakes

(2009) P. Viskelis et al.   JOURNAL OF FOOD SCIENCE

Goji (Lycium barbarumandL. chinense): Phytochemistry, Pharmacology and Safety in the Perspective of Traditional Uses and Recent Popularity

(2009) Olivier Potterat   PLANTA MEDICA

The history of antiretrovirals: key discoveries over the past 25 years

(2009) Erik De Clercq   REVIEWS IN MEDICAL VIROLOGY

Antiviral activity of Cleome rosea extracts from field-grown plants and tissue culture-derived materials against acyclovir-resistant Herpes simplex viruses type 1 (ACVr-HSV-1) and type 2 (ACVr-HSV-2)

(2009) Claudia Simões et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Optimization of the extraction of anthocyanin from Bokbunja (Rubus coreanus Miq.) marc produced during traditional wine processing and characterization of the extracts

(2008) C.S. Ku et al.   BIORESOURCE TECHNOLOGY

Anthocyanins and their role in cancer prevention

(2008) Li-Shu Wang et al.   CANCER LETTERS

Chemical studies of anthocyanins: A review

(2008) Araceli Castañeda-Ovando et al.   FOOD CHEMISTRY

A Deletion in the Chemokine Receptor 5(CCR5)Gene Is Associated with Tickborne Encephalitis

(2008) Elin Kindberg et al.   JOURNAL OF INFECTIOUS DISEASES

Role of the Hepatitis C Virus Core+1 Open Reading Frame and Core cis-Acting RNA Elements in Viral RNA Translation and Replication

(2008) N. Vassilaki et al.   JOURNAL OF VIROLOGY

Chocolate at heart: The anti-inflammatory impact of cocoa flavanols

(2008) Carlo Selmi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Multifunctional nanoparticles – properties and prospects for their use in human medicine

(2008) Nuria Sanvicens et al.   TRENDS IN BIOTECHNOLOGY

Restriction of retroviral replication by APOBEC3G/F and TRIM5α

(2008) Hendrik Huthoff et al.   TRENDS IN MICROBIOLOGY