Emerging Delivery Strategies of Carbon Monoxide for Therapeutic Applications: from CO Gas to CO Releasing Nanomaterials

Nanocarrier-mediated Delivery of CORM-2 Enhances Anti-allodynic and Anti-hyperalgesic Effects of CORM-2

(2019) Hari Prasad Joshi et al.   MOLECULAR NEUROBIOLOGY

A Versatile Carbon Monoxide Nanogenerator for Enhanced Tumor Therapy and Anti-Inflammation

(2019) Shi-Bo Wang et al.   ACS Nano

Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades

(2019) Xuefei Lu et al.   Nature Nanotechnology

Programmed ROS/CO-releasing nanomedicine for synergetic chemodynamic-gas therapy of cancer

(2019) Bin Zhao et al.   JOURNAL OF NANOBIOTECHNOLOGY

Graphdiyne Nanoparticles with High Free Radical Scavenging Activity for Radiation Protection

(2018) Jiani Xie et al.   ACS Applied Materials & Interfaces

Dual Intratumoral Redox/Enzyme-Responsive NO-Releasing Nanomedicine for the Specific, High-Efficacy, and Low-Toxic Cancer Therapy

(2018) Xiaobo Jia et al.   ADVANCED MATERIALS

Carbon monoxide in lung cell physiology and disease

(2018) Stefan W. Ryter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Stimuli-Responsive NO Release for On-Demand Gas-Sensitized Synergistic Cancer Therapy

(2018) Wenpei Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Broad-Spectrum Antimicrobial Potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation, Transcriptomic and Statistical Analyses, and Membrane Polarization

(2018) Lauren K. Wareham et al.   ANTIOXIDANTS & REDOX SIGNALING

Intelligent Metal Carbonyl Metal-Organic Framework Nanocomplex for Fluorescent Traceable H2 O2 -Triggered CO Delivery

(2018) Zhaokui Jin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Biomimetic carbon monoxide delivery based on hemoglobin vesicles ameliorates acute pancreatitis in mice via the regulation of macrophage and neutrophil activity

(2018) Kazuaki Taguchi et al.   DRUG DELIVERY

A Visible Light-activated Quinolone Carbon Monoxide-releasing Molecule: Prodrug and Albumin-assisted Delivery Enable Anti-cancer and Potent Anti-inflammatory Effects

(2018) Marina Popova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Emerging role of carbon monoxide in regulation of cellular pathways and in the maintenance of gastric mucosal integrity

(2018) Katarzyna Magierowska et al.   PHARMACOLOGICAL RESEARCH

Flexible Modulation of CO-Release Using Various Nuclearity of Metal Carbonyl Clusters on Graphene Oxide for Stroke Remediation

(2018) Mein Jin Tan et al.   Advanced Healthcare Materials

Exogenous/Endogenous-Triggered Mesoporous Silica Cancer Nanomedicine

(2018) Bowen Yang et al.   Advanced Healthcare Materials

The Antimicrobial Activity of a Carbon Monoxide Releasing Molecule (EBOR-CORM-1) Is Shaped by Intraspecific Variation within Pseudomonas aeruginosa Populations

(2018) Lindsey Flanagan et al.   Frontiers in Microbiology

PDT-Driven Highly Efficient Intracellular Delivery and Controlled Release of CO in Combination with Sufficient Singlet Oxygen Production for Synergistic Anticancer Therapy

(2018) Lihuang Wu et al.   ADVANCED FUNCTIONAL MATERIALS

Graphene-Based Smart Platforms for Combined Cancer Therapy

(2018) Zhanjun Gu et al.   ADVANCED MATERIALS

Gas-Generating Nanoplatforms: Material Chemistry, Multifunctionality, and Gas Therapy

(2018) Luodan Yu et al.   ADVANCED MATERIALS

X-Ray-Controlled Generation of Peroxynitrite Based on Nanosized LiLuF4 :Ce3+ Scintillators and their Applications for Radiosensitization

(2018) Zhen Du et al.   ADVANCED MATERIALS

Therapeutic Aspects of Carbon Monoxide in Cardiovascular Disease

(2018) Hyuk-Hoon Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mesoporous Metal-Organic Frameworks: Synthetic Strategies and Emerging Applications

(2018) Dingxin Liu et al.   Small

Carbon monoxide and its donors – their implications for medicine

(2018) Weronika Adach et al.   Future Medicinal Chemistry

Precise nanomedicine for intelligent therapy of cancer

(2018) Huabing Chen et al.   Science China-Chemistry

Functionalized MoS2 Nanovehicle with Near-Infrared Laser-Mediated Nitric Oxide Release and Photothermal Activities for Advanced Bacteria-Infected Wound Therapy

(2018) Qin Gao et al.   Small

Efficient Near Infrared Light Triggered Nitric Oxide Release Nanocomposites for Sensitizing Mild Photothermal Therapy

(2018) Xiao Zhang et al.   Advanced Science

Carbon monoxide sensitizes cisplatin-resistant ovarian cancer cell lines toward cisplatin via attenuation of levels of glutathione and nuclear metallothionein

(2018) Brian Kawahara et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

On-demand CO release for amplification of chemotherapy by MOF functionalized magnetic carbon nanoparticles with NIR irradiation

(2018) Jizong Yao et al.   BIOMATERIALS

Synthesis, Structures, and CO Release Capacity of a Family of Water-Soluble PhotoCORMs: Assessment of the Biocompatibility and Their Phototoxicity toward Human Breast Cancer Cells

(2017) Indranil Chakraborty et al.   INORGANIC CHEMISTRY

Aluminum Doped MCM-41 Nanoparticles as Platforms for the Dual Encapsulation of a CO-Releasing Molecule and Cisplatin

(2017) Francisco J. Carmona et al.   INORGANIC CHEMISTRY

Carbon Monoxide and Its Controlled Release: Therapeutic Application, Detection, and Development of Carbon Monoxide Releasing Molecules (CORMs)

(2017) Ken Ling et al.   JOURNAL OF MEDICINAL CHEMISTRY

Attenuation of Antioxidant Capacity in Human Breast Cancer Cells by Carbon Monoxide through Inhibition of Cystathionine β-Synthase Activity: Implications in Chemotherapeutic Drug Sensitivity

(2017) Brian Kawahara et al.   JOURNAL OF MEDICINAL CHEMISTRY

Co-Registered Molecular Logic Gate with a CO-Releasing Molecule Triggered by Light and Peroxide

(2017) Upendar Reddy G et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Systemic application of carbon monoxide-releasing molecule 3 protects skeletal muscle from ischemia-reperfusion injury

(2017) Aurelia Bihari et al.   JOURNAL OF VASCULAR SURGERY

MRI-guided and ultrasound-triggered release of NO by advanced nanomedicine

(2017) Zhaokui Jin et al.   Nanoscale

Aspects of Carbon Monoxide in Form of CO-Releasing Molecules Used in Cancer Treatment: More Light on the Way

(2017) Malamati Kourti et al.   Oxidative Medicine and Cellular Longevity

Antimicrobial activity of carbon monoxide-releasing molecule [Mn(CO)3(tpa-κ3N)]Br versus multidrug-resistant isolates of Avian Pathogenic Escherichia coli and its synergy with colistin

(2017) Jonathan Betts et al.   PLoS One

Drug Delivery to the Brain across the Blood-Brain Barrier Using Nanomaterials

(2017) Yung-Hao Tsou et al.   Small

Light responsive metal–organic frameworks as controllable CO-releasing cell culture substrates

(2017) Stéphane Diring et al.   Chemical Science

Toxicity of tryptophan manganese(i) carbonyl (Trypto-CORM), against Neisseria gonorrhoeae

(2017) Jonathan S. Ward et al.   MedChemComm

Precision gas therapy using intelligent nanomedicine

(2017) Qianjun He   Biomaterials Science

Carbon monoxide-releasing molecule, CORM-3, modulates alveolar macrophage M1/M2 phenotype in vitro

(2017) Hiroko Yamamoto-Oka et al.   INFLAMMOPHARMACOLOGY

Near infrared light triggered nitric oxide releasing platform based on upconversion nanoparticles for synergistic therapy of cancer stem-like cells

(2017) Xiao Zhang et al.   Science Bulletin

Ultrasound-Triggered Nitric Oxide Release Platform Based on Energy Transformation for Targeted Inhibition of Pancreatic Tumor

(2016) Kun Zhang et al.   ACS Nano

Controllable CO Release Following Near-Infrared Light-Induced Cleavage of Iron Carbonyl Derivatized Prussian Blue Nanoparticles for CO-Assisted Synergistic Treatment

(2016) Wei-Peng Li et al.   ACS Nano

Bactericidal Effect of a Photoresponsive Carbon Monoxide-Releasing Nonwoven against Staphylococcus aureus Biofilms

(2016) Mareike Klinger-Strobel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Heme Oxygenase-1/Carbon Monoxide System and Embryonic Stem Cell Differentiation and Maturation into Cardiomyocytes

(2016) Hagir B. Suliman et al.   ANTIOXIDANTS & REDOX SIGNALING

Antimicrobial Activity of the Manganese Photoactivated Carbon Monoxide-Releasing Molecule [Mn(CO)3(tpa-κ3N)]+ Against a Pathogenic Escherichia coli that Causes Urinary Infections

(2016) Mariana Tinajero-Trejo et al.   ANTIOXIDANTS & REDOX SIGNALING

Polymeric Framboidal Nanoparticles Loaded with a Carbon Monoxide Donor via Phenylboronic Acid-Catechol Complexation

(2016) André J. van der Vlies et al.   BIOCONJUGATE CHEMISTRY

Carbon monoxide releasing molecule-2 (CORM-2) inhibits growth of multidrug-resistant uropathogenic Escherichia coli in biofilm and following host cell colonization

(2016) Charlotte Sahlberg Bang et al.   BMC MICROBIOLOGY

CO-releasing molecule (CORM) conjugate systems

(2016) Anna Christin Kautz et al.   DALTON TRANSACTIONS

Synthesis of oxime-based CO-releasing molecules, CORMs and their immobilization on maghemite nanoparticles for magnetic-field induced CO release

(2016) Hajo Meyer et al.   DALTON TRANSACTIONS

Enhanced acute anti-inflammatory effects of CORM-2-loaded nanoparticles via sustained carbon monoxide delivery

(2016) Omer Salman Qureshi et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Carbon monoxide promotes gastric wound healing in mice via the protein kinase C pathway

(2016) Tomohisa Takagi et al.   FREE RADICAL RESEARCH

Cation Exchange Strategy for the Encapsulation of a Photoactive CO-Releasing Organometallic Molecule into Anionic Porous Frameworks

(2016) Francisco J. Carmona et al.   INORGANIC CHEMISTRY

A Theranostic Two-Tone Luminescent PhotoCORM Derived from Re(I) and (2-Pyridyl)-benzothiazole: Trackable CO Delivery to Malignant Cells

(2016) Samantha J. Carrington et al.   INORGANIC CHEMISTRY

Carbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties

(2016) Saori Nagao et al.   International Journal of Nanomedicine

Evaluation of a new type of nano-sized carbon monoxide donor on treating mice with experimentally induced colitis

(2016) Saori Nagao et al.   JOURNAL OF CONTROLLED RELEASE

Toward Carbon Monoxide–Based Therapeutics: Critical Drug Delivery and Developability Issues

(2016) Xingyue Ji et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Interaction of CORM-2 with Block Copolymers Containing Poly(4-vinylpyridine): Macromolecular Scaffolds for Carbon Monoxide Delivery in Biological Systems

(2016) Diep Nguyen et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth

(2016) Zsuzsanna Nemeth et al.   Oncotarget

Polymer–protein hybrid scaffolds as carriers for CORM-3: platforms for the delivery of carbon monoxide (CO)

(2016) Diep Nguyen et al.   RSC Advances

NIR-Responsive On-Demand Release of CO from Metal Carbonyl-Caged Graphene Oxide Nanomedicine

(2015) Qianjun He et al.   ADVANCED MATERIALS

Carbon monoxide in the treatment of sepsis

(2015) Kiichi Nakahira et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A Photoactive Carbon-Monoxide-Releasing Protein Cage for Dose-Regulated Delivery in Living Cells

(2015) Kenta Fujita et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, Mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO)3Cl(glycinate)] Actions on a Heme-Deficient Mutant of Escherichia coli

(2015) Jayne Louise Wilson et al.   ANTIOXIDANTS & REDOX SIGNALING

CO-Releasing Polymers Exert Antimicrobial Activity

(2015) Diep Nguyen et al.   BIOMACROMOLECULES

An artificial CO-releasing metalloprotein built by histidine-selective metallation

(2015) Inês S. Albuquerque et al.   CHEMICAL COMMUNICATIONS

A photoCORM nanocarrier for CO release using NIR light

(2015) Agustin E. Pierri et al.   CHEMICAL COMMUNICATIONS

Design of a CO-releasing Extracellular Scaffold Using in Vivo Protein Crystals

(2015) Hiroyasu Tabe et al.   CHEMISTRY LETTERS

Rapid Eradication of Human Breast Cancer Cells through Trackable Light-Triggered CO Delivery by Mesoporous Silica Nanoparticles Packed with a Designed photoCORM

(2015) Indranil Chakraborty et al.   CHEMISTRY OF MATERIALS

Quantum-CORMs: quantum dot sensitized CO releasing molecules

(2015) A. Ruggi et al.   DALTON TRANSACTIONS

Haeme oxygenase signalling pathway: implications for cardiovascular disease

(2015) Laura E. Fredenburgh et al.   EUROPEAN HEART JOURNAL

Stabilizing Alginate Confinement and Polymer Coating of CO-Releasing Molecules Supported on Iron Oxide Nanoparticles To Trigger the CO Release by Magnetic Heating

(2015) Hajo Meyer et al.   INORGANIC CHEMISTRY

Folic acid-tagged protein nanoemulsions loaded with CORM-2 enhance the survival of mice bearing subcutaneous A20 lymphoma tumors

(2015) Ana Loureiro et al.   Nanomedicine-Nanotechnology Biology and Medicine

Gasotransmitters in cancer: from pathophysiology to experimental therapy

(2015) Csaba Szabo   NATURE REVIEWS DRUG DISCOVERY

Carbon monoxide inhibits sprouting angiogenesis and vascular endothelial growth factor receptor-2 phosphorylation

(2015) Peter W. Hewett et al.   THROMBOSIS AND HAEMOSTASIS

HO-1/CO system in tumor growth, angiogenesis and metabolism — Targeting HO-1 as an anti-tumor therapy

(2015) Agnieszka Loboda et al.   VASCULAR PHARMACOLOGY

Design of biomaterials for intracellular delivery of carbon monoxide

(2015) Hiroshi Inaba et al.   Biomaterials Science

Macromolecular and Inorganic Nanomaterials Scaffolds for Carbon Monoxide Delivery: Recent Developments and Future Trends

(2015) Diep Nguyen et al.   ACS Biomaterials-Science & Engineering

Macromolecular and Inorganic Nanomaterials Scaffolds for Carbon Monoxide Delivery: Recent Developments and Future Trends

(2015) Diep Nguyen et al.   ACS Biomaterials Science & Engineering

Spontaneous CO Release from RuII(CO)2-Protein Complexes in Aqueous Solution, Cells, and Mice

(2014) Miguel Chaves-Ferreira et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon-Monoxide-Releasing Molecules for the Delivery of Therapeutic CO In Vivo

(2014) Sandra García-Gallego et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs)

(2014) U Schatzschneider   BRITISH JOURNAL OF PHARMACOLOGY

Carbon monoxide is not always a poison gas for human organism: Physiological and pharmacological features of CO

(2014) Beata Olas   CHEMICO-BIOLOGICAL INTERACTIONS

Antiproliferative effects of carbon monoxide on pancreatic cancer

(2014) Libor Vítek et al.   DIGESTIVE AND LIVER DISEASE

Sonogashira, CuAAC, and Oxime Ligations for the Synthesis of MnITricarbonyl PhotoCORM Peptide Conjugates

(2014) Sandesh Pai et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Preparation of a Cross-Linked Porous Protein Crystal Containing Ru Carbonyl Complexes as a CO-Releasing Extracellular Scaffold

(2014) Hiroyasu Tabe et al.   INORGANIC CHEMISTRY

Macrophages sense and kill bacteria through carbon monoxide–dependent inflammasome activation

(2014) Barbara Wegiel et al.   JOURNAL OF CLINICAL INVESTIGATION

Styrene-maleic acid copolymer-encapsulated CORM2, a water-soluble carbon monoxide (CO) donor with a constant CO-releasing property, exhibits therapeutic potential for inflammatory bowel disease

(2014) Hongzhuan Yin et al.   JOURNAL OF CONTROLLED RELEASE

Intracellular CO Release from Composite of Ferritin and Ruthenium Carbonyl Complexes

(2014) Kenta Fujita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light-triggered carbon monoxide delivery with Al-MCM-41-based nanoparticles bearing a designed manganese carbonyl complex

(2014) Margarita A. Gonzales et al.   Journal of Materials Chemistry B

Light-triggered CO release from nanoporous non-wovens

(2014) Carmen Bohlender et al.   Journal of Materials Chemistry B

Different design of enzyme-triggered CO-releasing molecules (ET-CORMs) reveals quantitative differences in biological activities in terms of toxicity and inflammation

(2014) E. Stamellou et al.   Redox Biology

Interplay Between Heme Oxygenase-1 and miR-378 Affects Non-Small Cell Lung Carcinoma Growth, Vascularization, and Metastasis

(2013) Klaudia Skrzypek et al.   ANTIOXIDANTS & REDOX SIGNALING

Carbon Monoxide Confers Protection in Sepsis by Enhancing Beclin 1-Dependent Autophagy and Phagocytosis

(2013) Seonmin Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

(2013) B. Wegiel et al.   CANCER RESEARCH

Metal carbonyls supported on iron oxide nanoparticles to trigger the CO-gasotransmitter release by magnetic heating

(2013) Peter C. Kunz et al.   CHEMICAL COMMUNICATIONS

Enzyme-triggered CO-releasing molecules (ET-CORMs): Evaluation of biological activity in relation to their structure

(2013) S. Romanski et al.   FREE RADICAL BIOLOGY AND MEDICINE

CO and CO-releasing molecules in medicinal chemistry

(2013) Fabio Zobi   Future Medicinal Chemistry

Next Generation PhotoCORMs: Polynuclear Tricarbonylmanganese(I)-Functionalized Polypyridyl Metallodendrimers

(2013) Preshendren Govender et al.   INORGANIC CHEMISTRY

Low concentration of exogenous carbon monoxide protects mammalian cells against proliferation induced by radiation-induced bystander effect

(2013) Liping Tong et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Carbon Monoxide Attenuates Dextran Sulfate Sodium-Induced Colitis via Inhibition of GSK-3βSignaling

(2013) Md. Jamal Uddin et al.   Oxidative Medicine and Cellular Longevity

The Bactericidal Activity of Carbon Monoxide–Releasing Molecules against Helicobacter pylori

(2013) Ana F. Tavares et al.   PLoS One

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

Antibacterial Effects of Carbon Monoxide

(2012) Jayne Louise Wilson et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Acyloxybutadiene tricarbonyl iron complexes as enzyme-triggered CO-releasing molecules (ET-CORMs): a structure–activity relationship study

(2012) Steffen Romanski et al.   DALTON TRANSACTIONS

A role for reactive oxygen species in the antibacterial properties of carbon monoxide-releasing molecules

(2012) Ana Filipa N. Tavares et al.   FEMS MICROBIOLOGY LETTERS

Syntheses, Structures, and Properties of New Manganese Carbonyls as Photoactive CO-Releasing Molecules: Design Strategies That Lead to CO Photolability in the Visible Region

(2012) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

Bioorthogonal oxime ligation of a Mo(CO)4(N–N) CO-releasing molecule (CORM) to a TGF β-binding peptide

(2012) Hendrik Pfeiffer et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

A Luminescent and Biocompatible PhotoCORM

(2012) Agustin E. Pierri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron Dienylphosphate Tricarbonyl Complexes as Water-Soluble Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2012) Steffen Romanski et al.   ORGANOMETALLICS

Carbon monoxide: Mechanisms of action and potential clinical implications

(2012) Luc Rochette et al.   PHARMACOLOGY & THERAPEUTICS

A peptide-based material for therapeutic carbon monoxide delivery

(2012) John B. Matson et al.   Soft Matter

Nanostructure-templated control of drug release from peptide amphiphile nanofiber gels

(2012) John B. Matson et al.   Soft Matter

Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2011) Steffen Romanski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention effect in solid tumors

(2011) Jun Fang et al.   CANCER SCIENCE

Therapeutic potential of carbon monoxide in multiple sclerosis

(2011) P. Fagone et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Polymer Conjugates of Photoinducible CO-Releasing Molecules

(2011) Nadine E. Brückmann et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Synthesis, Characterization, and Reactivity of the Stable Iron Carbonyl Complex [Fe(CO)(N4Py)](ClO4)2: Photoactivated Carbon Monoxide Release, Growth Inhibitory Activity, and Peptide Ligation

(2011) Casey S. Jackson et al.   INORGANIC CHEMISTRY

Manganese Carbonyls Bearing Tripodal Polypyridine Ligands as Photoactive Carbon Monoxide-Releasing Molecules

(2011) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

Reactive Oxygen Species Mediate Bactericidal Killing Elicited by Carbon Monoxide-releasing Molecules

(2011) Ana Filipa N. Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Anti-Inflammatory Role for Carbon Monoxide and Heme Oxygenase-1 in Chronic Th2-Mediated Murine Colitis

(2011) S. Z. Sheikh et al.   JOURNAL OF IMMUNOLOGY

Beneficial effects of carbon monoxide-releasing molecule-2 (CORM-2) on acute doxorubicin cardiotoxicity in mice: Role of oxidative stress and apoptosis

(2011) Hitesh Soni et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nitric Oxide–Dependent Bone Marrow Progenitor Mobilization by Carbon Monoxide Enhances Endothelial Repair After Vascular Injury

(2010) Barbara Wegiel et al.   CIRCULATION

Inhalation of Carbon Monoxide Ameliorates TNBS-Induced Colitis in Mice Through the Inhibition of TNF-α Expression

(2010) Tomohisa Takagi et al.   DIGESTIVE DISEASES AND SCIENCES

CO Releasing Properties and Cytoprotective Effect ofcis-trans- [ReII(CO)2Br2L2]nComplexes

(2010) Fabio Zobi et al.   INORGANIC CHEMISTRY

Carbon Monoxide-Releasing Micelles for Immunotherapy

(2010) Urara Hasegawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Carbon monoxide prevents ventilator-induced lung injury via caveolin-1*

(2009) Alexander Hoetzel et al.   CRITICAL CARE MEDICINE

Carbon monoxide is a poison … to microbes! CO as a bactericidal molecule

(2009) Beek Yoke Chin et al.   CURRENT OPINION IN PHARMACOLOGY

Sonogashira and “Click” reactions for the N-terminal and side-chain functionalization of peptides with [Mn(CO)3(tpm)]+-based CO releasing molecules (tpm = tris(pyrazolyl)methane)

(2009) Hendrik Pfeiffer et al.   DALTON TRANSACTIONS

Tricarbonylmanganese(I) and –rhenium(I) Complexes of Imidazol-Based Phosphane Ligands: Influence of the Substitution Pattern on the CO Release Properties

(2009) Peter C. Kunz et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

A Photochemical Precursor for Carbon Monoxide Release in Aerated Aqueous Media

(2009) R. Dale Rimmer et al.   INORGANIC CHEMISTRY

The Heme Oxygenase-1/Carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-1

(2009) X. M. Wang et al.   JOURNAL OF IMMUNOLOGY

Exploring the antimicrobial action of a carbon monoxide-releasing compound through whole-genome transcription profiling of Escherichia coli

(2009) L. S. Nobre et al.   MICROBIOLOGY-SGM

Heme-Oxygenase-1 Induction and Carbon Monoxide-Releasing Molecule Inhibit Lipopolysaccharide (LPS)-Induced High-Mobility Group Box 1 Release in Vitro and Improve Survival of Mice in LPS- and Cecal Ligation and Puncture-Induced Sepsis Model in Vivo

(2009) K. Tsoyi et al.   MOLECULAR PHARMACOLOGY

Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex

(2008) Johanna Niesel et al.   CHEMICAL COMMUNICATIONS

A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia

(2008) Mathieu Desmard et al.   FASEB JOURNAL

Use of carbon monoxide as a therapeutic agent: promises and challenges

(2008) Roberta Foresti et al.   INTENSIVE CARE MEDICINE

Carbon Monoxide-releasing Antibacterial Molecules Target Respiration and Global Transcriptional Regulators

(2008) Kelly S. Davidge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme oxygenase-1–derived carbon monoxide enhances the host defense response to microbial sepsis in mice

(2008) Su Wol Chung et al.   JOURNAL OF CLINICAL INVESTIGATION

Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9

(2008) C.-W. Lin et al.   MOLECULAR CANCER THERAPEUTICS

Carbon monoxide liberated from carbon monoxide-releasing molecule CORM-2 attenuates inflammation in the liver of septic mice

(2007) Gediminas Cepinskas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY