Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs)

The Concise Guide to PHARMACOLOGY 2013/14: Ligand-Gated Ion Channels

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: Ion Channels

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metal carbonyls supported on iron oxide nanoparticles to trigger the CO-gasotransmitter release by magnetic heating

(2013) Peter C. Kunz et al.   CHEMICAL COMMUNICATIONS

Iron Metal-Organic Frameworks MIL-88B and NH2-MIL-88B for the Loading and Delivery of the Gasotransmitter Carbon Monoxide

(2013) Mingyan Ma et al.   CHEMISTRY-A EUROPEAN JOURNAL

CO and CO-releasing molecules in medicinal chemistry

(2013) Fabio Zobi   Future Medicinal Chemistry

Next Generation PhotoCORMs: Polynuclear Tricarbonylmanganese(I)-Functionalized Polypyridyl Metallodendrimers

(2013) Preshendren Govender et al.   INORGANIC CHEMISTRY

Determination of Carbon Monoxide in Tuna by Gas Chromatography with Micro-Thermal Conductivity Detector

(2013) C. Bernardi et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores

(2013) Ping Peng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Fluorescein Analogue Xanthene-9-Carboxylic Acid: A Transition-Metal-Free CO Releasing Molecule Activated by Green Light

(2013) Lovely Angel Panamparambil Antony et al.   ORGANIC LETTERS

Synthesis and Performance of Acyloxy-diene-Fe(CO)3 Complexes with Variable Chain Lengths as Enzyme-Triggered Carbon Monoxide-Releasing Molecules

(2013) Svetlana Botov et al.   ORGANOMETALLICS

Sulfite species enhance carbon monoxide release from CO-releasing molecules: Implications for the deoxymyoglobin assay of activity

(2012) Samantha McLean et al.   ANALYTICAL BIOCHEMISTRY

A Selective Fluorescent Probe for Carbon Monoxide Imaging in Living Cells

(2012) Jing Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lighting up Carbon Monoxide: Fluorescent Probes for Monitoring CO in Living Cells

(2012) Lin Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure and Regulation of Soluble Guanylate Cyclase

(2012) Emily R. Derbyshire et al.   Annual Review of Biochemistry

Redox, haem and CO in enzymatic catalysis and regulation

(2012) Stephen W. Ragsdale et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

CuAAC click functionalization of azide-modified nanodiamond with a photoactivatable CO-releasing molecule (PhotoCORM) based on [Mn(CO)3(tpm)]+

(2012) G. Dördelmann et al.   CHEMICAL COMMUNICATIONS

Small Molecule Signaling Agents: The Integrated Chemistry and Biochemistry of Nitrogen Oxides, Oxides of Carbon, Dioxygen, Hydrogen Sulfide, and Their Derived Species

(2012) Jon M. Fukuto et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

Interaction of Carbon Monoxide with Transition Metals: Evolutionary Insights into Drug Target Discovery

(2012) Roberta Foresti et al.   CURRENT DRUG TARGETS

Acyloxybutadiene tricarbonyl iron complexes as enzyme-triggered CO-releasing molecules (ET-CORMs): a structure–activity relationship study

(2012) Steffen Romanski et al.   DALTON TRANSACTIONS

A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM)

(2012) Jonathan S. Ward et al.   DALTON TRANSACTIONS

Characterization of a versatile organometallic pro-drug (CORM) for experimental CO based therapeutics

(2012) João D. Seixas et al.   DALTON TRANSACTIONS

Syntheses, Structures, and Properties of New Manganese Carbonyls as Photoactive CO-Releasing Molecules: Design Strategies That Lead to CO Photolability in the Visible Region

(2012) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

New insights into the chemistry of fac-[Ru(CO)3]2+ fragments in biologically relevant conditions: The CO releasing activity of [Ru(CO)3Cl2(1,3-thiazole)], and the X-ray crystal structure of its adduct with lysozyme

(2012) M.F.A. Santos et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Bioorthogonal oxime ligation of a Mo(CO)4(N–N) CO-releasing molecule (CORM) to a TGF β-binding peptide

(2012) Hendrik Pfeiffer et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

A Reaction-Based Fluorescent Probe for Selective Imaging of Carbon Monoxide in Living Cells Using a Palladium-Mediated Carbonylation

(2012) Brian W. Michel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Luminescent and Biocompatible PhotoCORM

(2012) Agustin E. Pierri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron Dienylphosphate Tricarbonyl Complexes as Water-Soluble Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2012) Steffen Romanski et al.   ORGANOMETALLICS

Generation of Carbon Monoxide Releasing Molecules (CO-RMs) as Drug Candidates for the Treatment of Acute Liver Injury: Targeting of CO-RMs to the Liver

(2012) Ana R. Marques et al.   ORGANOMETALLICS

Carbon monoxide: Mechanisms of action and potential clinical implications

(2012) Luc Rochette et al.   PHARMACOLOGY & THERAPEUTICS

Solubility and Permeation of Hydrogen Sulfide in Lipid Membranes

(2012) Ernesto Cuevasanta et al.   PLoS One

Gas biology: Tiny molecules controlling metabolic systems

(2012) Mayumi Kajimura et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

A peptide-based material for therapeutic carbon monoxide delivery

(2012) John B. Matson et al.   Soft Matter

The social network of carbon monoxide in medicine

(2012) Barbara Wegiel et al.   TRENDS IN MOLECULAR MEDICINE

Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2011) Steffen Romanski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrogen Sulfide and Cell Signaling

(2011) Ling Li et al.   Annual Review of Pharmacology and Toxicology

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Photochemically activated carbon monoxide release for biological targets. Toward developing air-stable photoCORMs labilized by visible light

(2011) R. Dale Rimmer et al.   COORDINATION CHEMISTRY REVIEWS

Modification of the deoxy-myoglobin/carbonmonoxy-myoglobin UV-vis assay for reliable determination of CO-release rates from organometallic carbonyl complexes

(2011) Anthony J. Atkin et al.   DALTON TRANSACTIONS

17 e−rhenium dicarbonyl CO-releasing molecules on a cobalamin scaffold for biological application

(2011) Fabio Zobi et al.   DALTON TRANSACTIONS

Manganese Carbonyls Bearing Tripodal Polypyridine Ligands as Photoactive Carbon Monoxide-Releasing Molecules

(2011) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

Designed Iron Carbonyls as Carbon Monoxide (CO) Releasing Molecules: Rapid CO Release and Delivery to Myoglobin in Aqueous Buffer, and Vasorelaxation of Mouse Aorta

(2011) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

Silicium Dioxide Nanoparticles As Carriers for Photoactivatable CO-Releasing Molecules (PhotoCORMs)

(2011) Gregor Dördelmann et al.   INORGANIC CHEMISTRY

PhotoCORMs: Light-triggered release of carbon monoxide from the coordination sphere of transition metal complexes for biological applications

(2011) Ulrich Schatzschneider   INORGANICA CHIMICA ACTA

Carbon monoxide: an emerging regulator of ion channels

(2011) William J. Wilkinson et al.   JOURNAL OF PHYSIOLOGY-LONDON

CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl−Lysozyme Complex

(2011) Teresa Santos-Silva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing Soluble Guanylate Cyclase Activation by CO and YC-1 Using Resonance Raman Spectroscopy

(2010) Mohammed Ibrahim et al.   BIOCHEMISTRY

Photoactivated Biological Activity of Transition-Metal Complexes

(2010) Ulrich Schatzschneider   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Thiol-disulfide Redox Dependence of Heme Binding and Heme Ligand Switching in Nuclear Hormone Receptor Rev-erbβ

(2010) Nirupama Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enzymatic Ring-Opening Mechanism of Verdoheme by the Heme Oxygenase: A Combined X-ray Crystallography and QM/MM Study

(2010) Wenzhen Lai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of Iron Dinitrosyl Species Formed in the Reaction of Nitric Oxide with a Biological Rieske Center

(2010) Christine E. Tinberg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbon Monoxide-Releasing Micelles for Immunotherapy

(2010) Urara Hasegawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Syntheses, structural characterization and CO releasing properties of boranocarbonate [H3BCO2H]− derivatives

(2010) Tamil Selvi Pitchumony et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Quantitating carbon monoxide production from heme by vascular plant preparations in vitro

(2010) Hendrik J. Vreman et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Gaseotransmitters: New Frontiers for Translational Science

(2010) C. Szabo   Science Translational Medicine

Heme Oxygenase Reveals Its Strategy for Catalyzing Three Successive Oxygenation Reactions

(2009) Toshitaka Matsui et al.   ACCOUNTS OF CHEMICAL RESEARCH

Interactions of Multiple Gas-Transducing Systems: Hallmarks and Uncertainties of CO, NO, and H2S Gas Biology

(2009) Mayumi Kajimura et al.   ANTIOXIDANTS & REDOX SIGNALING

Sonogashira and “Click” reactions for the N-terminal and side-chain functionalization of peptides with [Mn(CO)3(tpm)]+-based CO releasing molecules (tpm = tris(pyrazolyl)methane)

(2009) Hendrik Pfeiffer et al.   DALTON TRANSACTIONS

Areneruthenium complexes as anticancer agents

(2009) Georg Süss-Fink   DALTON TRANSACTIONS

X-ray Crystal Structure of Human Heme Oxygenase-1 with (2R,4S)-2-[2-(4-Chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-4[((5-trifluoromethylpyridin-2-yl)thio)methyl]-1,3-dioxolane: A Novel, Inducible Binding Mode

(2009) Mona N. Rahman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Heme Regulation of Human Cystathionine β-Synthase Activity: Insights from Fluorescence and Raman Spectroscopy

(2009) Colin L. Weeks et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent developments in ruthenium anticancer drugs

(2009) Aviva Levina et al.   Metallomics

Modulation of BKCa Channel Gating by Endogenous Signaling Molecules

(2009) Shangwei Hou et al.   PHYSIOLOGY

Signaling by Gasotransmitters

(2009) A. K. Mustafa et al.   Science Signaling

2.3 Å X-ray Structure of the Heme-Bound GAF Domain of Sensory Histidine Kinase DosT ofMycobacterium tuberculosis†‡

(2008) Larissa M. Podust et al.   BIOCHEMISTRY

Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex

(2008) Johanna Niesel et al.   CHEMICAL COMMUNICATIONS

Derivatives of Sodium Boranocarbonate as Novel CO-Releasing Molecules (CO-RMs)

(2008) Tamil S. Pitchumony et al.   CHIMIA

Carbon monoxide, reactive oxygen signaling, and oxidative stress

(2008) Claude A. Piantadosi   FREE RADICAL BIOLOGY AND MEDICINE

X-ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 1-(Adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone: A Common Binding Mode for Imidazole-Based Heme Oxygenase-1 Inhibitors#

(2008) Mona N. Rahman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quantum Mechanical/Molecular Mechanical Study of Mechanisms of Heme Degradation by the Enzyme Heme Oxygenase:  The Strategic Function of the Water Cluster

(2008) Hui Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS

The RCK1 high-affinity Ca2+ sensor confers carbon monoxide sensitivity to Slo1 BK channels

(2008) S. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA