CO and CO-releasing molecules in medicinal chemistry

Sulfite species enhance carbon monoxide release from CO-releasing molecules: Implications for the deoxymyoglobin assay of activity

(2012) Samantha McLean et al.   ANALYTICAL BIOCHEMISTRY

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

Theoretical Insights into the Mechanism of Carbon Monoxide (CO) Release from CO-Releasing Molecules

(2012) Sai Vikrama Chaitanya Vummaleti et al.   CHEMISTRY-A EUROPEAN JOURNAL

Interaction of Carbon Monoxide with Transition Metals: Evolutionary Insights into Drug Target Discovery

(2012) Roberta Foresti et al.   CURRENT DRUG TARGETS

Acyloxybutadiene tricarbonyl iron complexes as enzyme-triggered CO-releasing molecules (ET-CORMs): a structure–activity relationship study

(2012) Steffen Romanski et al.   DALTON TRANSACTIONS

A Comparative Study of Tricarbonylmanganese Photoactivatable CO Releasing Molecules (PhotoCORMs) by Using the Myoglobin Assay and Time-Resolved IR Spectroscopy

(2012) Wilhelm Huber et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Preconditioning of Carbon Monoxide Releasing Molecule-derived CO Attenuates LPS-induced Activation of HUVEC

(2012) Bingwei Sun et al.   International Journal of Biological Sciences

Carbon Monoxide Modulates Apoptosis by Reinforcing Oxidative Metabolism in Astrocytes

(2012) Ana S. Almeida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Types of CO-Releasing Molecules (CO-RMs), Based on Iron Dithiocarbamate Complexes and [Fe(CO)3I(S2COEt)]

(2012) Lindsay Hewison et al.   ORGANOMETALLICS

CO-Releasing Molecules: A Personal View

(2012) Brian E. Mann   ORGANOMETALLICS

CO Release from Norbornadiene Iron(0) Tricarbonyl Complexes: Importance of Ligand Dissociation

(2012) Anthony J. Atkin et al.   ORGANOMETALLICS

Generation of Carbon Monoxide Releasing Molecules (CO-RMs) as Drug Candidates for the Treatment of Acute Liver Injury: Targeting of CO-RMs to the Liver

(2012) Ana R. Marques et al.   ORGANOMETALLICS

The comparison of antithrombotic properties of CORM-3 and CORM-A1 in arterial thrombosis in rats

(2012) Karol Kramkowski et al.   VASCULAR PHARMACOLOGY

Corrigendum: Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2011) Steffen Romanski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Novel Carbon Monoxide-Releasing Molecule Fully Protects Mice from Severe Malaria

(2011) Ana C. Pena et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Prevention of clinical and histological signs of proteolipid protein (PLP)-induced experimental allergic encephalomyelitis (EAE) in mice by the water-soluble carbon monoxide-releasing molecule (CORM)-A1

(2011) P. Fagone et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Photochemically activated carbon monoxide release for biological targets. Toward developing air-stable photoCORMs labilized by visible light

(2011) R. Dale Rimmer et al.   COORDINATION CHEMISTRY REVIEWS

Towards Improved Therapeutic CORMs: Understanding the Reactivity of CORM-3 with Proteins

(2011) T. Santos-Silva et al.   CURRENT MEDICINAL CHEMISTRY

Reactivity of 17 e− Complex [ReIIBr4(CO)2]2− with Bridging Aromatic Ligands. Characterization and CO-Releasing Properties

(2011) Fabio Zobi et al.   DALTON TRANSACTIONS

[Mn(CO)4{S2CNMe(CH2CO2H)}], a new water-soluble CO-releasing molecule

(2011) Sian H. Crook et al.   DALTON TRANSACTIONS

Modification of the deoxy-myoglobin/carbonmonoxy-myoglobin UV-vis assay for reliable determination of CO-release rates from organometallic carbonyl complexes

(2011) Anthony J. Atkin et al.   DALTON TRANSACTIONS

17 e−rhenium dicarbonyl CO-releasing molecules on a cobalamin scaffold for biological application

(2011) Fabio Zobi et al.   DALTON TRANSACTIONS

Divergent mechanisms involved in CO and CORM-2 induced vasorelaxation

(2011) Kelly Decaluwé et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Growing PAINS in academic drug discovery

(2011) Adrian Whitty   Future Medicinal Chemistry

Synthesis, Characterization, and Reactivity of the Stable Iron Carbonyl Complex [Fe(CO)(N4Py)](ClO4)2: Photoactivated Carbon Monoxide Release, Growth Inhibitory Activity, and Peptide Ligation

(2011) Casey S. Jackson et al.   INORGANIC CHEMISTRY

Designed Iron Carbonyls as Carbon Monoxide (CO) Releasing Molecules: Rapid CO Release and Delivery to Myoglobin in Aqueous Buffer, and Vasorelaxation of Mouse Aorta

(2011) Margarita A. Gonzalez et al.   INORGANIC CHEMISTRY

Tetrachlorocarbonyliridates: Water-Soluble Carbon Monoxide Releasing Molecules Rate-Modulated by the Sixth Ligand

(2011) Damian E. Bikiel et al.   INORGANIC CHEMISTRY

Silicium Dioxide Nanoparticles As Carriers for Photoactivatable CO-Releasing Molecules (PhotoCORMs)

(2011) Gregor Dördelmann et al.   INORGANIC CHEMISTRY

PhotoCORMs: Light-triggered release of carbon monoxide from the coordination sphere of transition metal complexes for biological applications

(2011) Ulrich Schatzschneider   INORGANICA CHIMICA ACTA

Reactive Oxygen Species Mediate Bactericidal Killing Elicited by Carbon Monoxide-releasing Molecules

(2011) Ana Filipa N. Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis and Reactivity of Molybdenum Complexes Containing Functionalized Alkynyl Ligands: A Photochemically Activated CO-Releasing Molecule (PhotoCO-RM)

(2011) Wei-Qiang Zhang et al.   ORGANOMETALLICS

Synthesis, Structures, and CO Releasing Properties of two Tricarbonyl Manganese(I) Complexes

(2011) Fabian Mohr et al.   ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE

Label-Free Imaging of Metal-Carbonyl Complexes in Live Cells by Raman Microspectroscopy

(2010) Konrad Meister et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron indenyl carbonyl compounds: CO-releasing molecules

(2010) Lindsay Hewison et al.   DALTON TRANSACTIONS

Photoactivated Biological Activity of Transition-Metal Complexes

(2010) Ulrich Schatzschneider   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Carbon monoxide-releasing molecule CORM-3 suppresses vascular endothelial cell SOD-1/SOD-2 activity while up-regulating the cell surface levels of SOD-3 in a heparin-dependent manner

(2010) Shinjiro Mizuguchi et al.   FREE RADICAL BIOLOGY AND MEDICINE

CO Releasing Properties and Cytoprotective Effect ofcis-trans- [ReII(CO)2Br2L2]nComplexes

(2010) Fabio Zobi et al.   INORGANIC CHEMISTRY

Group 6 Carbon Monoxide-Releasing Metal Complexes with Biologically-Compatible Leaving Groups

(2010) Wei-Qiang Zhang et al.   INORGANIC CHEMISTRY

Knockdown of heme oxygenase-2 impairs corneal epithelial cell wound healing

(2010) Adna Halilovic et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dicarbonyl-bis(cysteamine)iron(II): A light induced carbon monoxide releasing molecule based on iron (CORM-S1)

(2010) Robert Kretschmer et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

CO-releasing properties of cis-trans-[ReII(CO)2Br2L2]n complexes

(2010) Fabio Zobi et al.   NUCLEAR MEDICINE AND BIOLOGY

Syntheses, structural characterization and CO releasing properties of boranocarbonate [H3BCO2H]− derivatives

(2010) Tamil Selvi Pitchumony et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Heme Oxygenase-2 and Large-Conductance Ca2+-activated K+Channels

(2009) Markus Roth et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Protective effects of a carbon monoxide-releasing molecule (CORM-3) during hepatic cold preservation

(2009) M.D. Pizarro et al.   CRYOBIOLOGY

μ2-Alkyne dicobalt(0)hexacarbonyl complexes as carbon monoxide-releasing molecules (CO-RMs): probing the release mechanism

(2009) Anthony J. Atkin et al.   DALTON TRANSACTIONS

Tricarbonylmanganese(I) and –rhenium(I) Complexes of Imidazol-Based Phosphane Ligands: Influence of the Substitution Pattern on the CO Release Properties

(2009) Peter C. Kunz et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Therapeutic applications of the gaseous mediators carbon monoxide and hydrogen sulfide

(2009) Gerard L Bannenberg et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A Photochemical Precursor for Carbon Monoxide Release in Aerated Aqueous Media

(2009) R. Dale Rimmer et al.   INORGANIC CHEMISTRY

Carbon Monoxide Rescues Mice from Lethal Sepsis by Supporting Mitochondrial Energetic Metabolism and Activating Mitochondrial Biogenesis

(2009) S. Lancel et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex

(2008) Johanna Niesel et al.   CHEMICAL COMMUNICATIONS

Derivatives of Sodium Boranocarbonate as Novel CO-Releasing Molecules (CO-RMs)

(2008) Tamil S. Pitchumony et al.   CHIMIA

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1

(2008) Claude A. Piantadosi et al.   CIRCULATION RESEARCH

A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia

(2008) Mathieu Desmard et al.   FASEB JOURNAL

Carbon Monoxide-releasing Antibacterial Molecules Target Respiration and Global Transcriptional Regulators

(2008) Kelly S. Davidge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS

trans-Arachidonic acids induce a heme oxygenase-dependent vasorelaxation of cerebral microvasculature

(2007) Amna Kooli et al.   FREE RADICAL BIOLOGY AND MEDICINE