PDT-Driven Highly Efficient Intracellular Delivery and Controlled Release of CO in Combination with Sufficient Singlet Oxygen Production for Synergistic Anticancer Therapy

Virion-Like Membrane-Breaking Nanoparticles with Tumor-Activated Cell-and-Tissue Dual-Penetration Conquer Impermeable Cancer

(2018) Xiao Zhang et al.   ADVANCED MATERIALS

Rational Design of Conjugated Photosensitizers with Controllable Photoconversion for Dually Cooperative Phototherapy

(2018) Shuyue Ye et al.   ADVANCED MATERIALS

Nanoscale Metal–Organic Framework Overcomes Hypoxia for Photodynamic Therapy Primed Cancer Immunotherapy

(2018) Guangxu Lan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of a Light-Controlled Nanoplatform for Direct Nuclear Delivery of Molecular and Nanoscale Materials

(2018) Ya-Xuan Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide

(2018) Yueqin Zheng et al.   Nature Chemistry

Recent advances in anti-angiogenic nanomedicines for cancer therapy

(2018) Pravin Bhattarai et al.   Nanoscale

Aspects of Carbon Monoxide in Form of CO-Releasing Molecules Used in Cancer Treatment: More Light on the Way

(2017) Malamati Kourti et al.   Oxidative Medicine and Cellular Longevity

Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions

(2017) Demian van Straten et al.   Cancers

Bioreducible Fluorinated Peptide Dendrimers Capable of Circumventing Various Physiological Barriers for Highly Efficient and Safe Gene Delivery

(2016) Xiaojun Cai et al.   ACS Applied Materials & Interfaces

Rational Design of Multi-Stimuli-Responsive Nanoparticles for Precise Cancer Therapy

(2016) Xiaonan An et al.   ACS Nano

Tumor-Specific Multiple Stimuli-Activated Dendrimeric Nanoassemblies with Metabolic Blockade Surmount Chemotherapy Resistance

(2016) Yachao Li et al.   ACS Nano

Controllable CO Release Following Near-Infrared Light-Induced Cleavage of Iron Carbonyl Derivatized Prussian Blue Nanoparticles for CO-Assisted Synergistic Treatment

(2016) Wei-Peng Li et al.   ACS Nano

Light-Responsive, Singlet-Oxygen-Triggered On-Demand Drug Release from Photosensitizer-Doped Mesoporous Silica Nanorods for Cancer Combination Therapy

(2016) Guangbao Yang et al.   ADVANCED FUNCTIONAL MATERIALS

Bifunctional Platinated Nanoparticles for Photoinduced Tumor Ablation

(2016) Zhengqing Guo et al.   ADVANCED MATERIALS

Catalase-Loaded TaOx Nanoshells as Bio-Nanoreactors Combining High-Z Element and Enzyme Delivery for Enhancing Radiotherapy

(2016) Guosheng Song et al.   ADVANCED MATERIALS

Readily Available Fluorescent Probe for Carbon Monoxide Imaging in Living Cells

(2016) Weiyong Feng et al.   ANALYTICAL CHEMISTRY

Click and Release: A Chemical Strategy toward Developing Gasotransmitter Prodrugs by Using an Intramolecular Diels-Alder Reaction

(2016) Xingyue Ji et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simple Peptide-Tuned Self-Assembly of Photosensitizers towards Anticancer Photodynamic Therapy

(2016) Kai Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Smart Photosensitizer-Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells

(2016) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Vascular and angiogenic activities of CORM-401, an oxidant-sensitive CO-releasing molecule

(2016) Sarah Fayad-Kobeissi et al.   BIOCHEMICAL PHARMACOLOGY

Polymeric Framboidal Nanoparticles Loaded with a Carbon Monoxide Donor via Phenylboronic Acid-Catechol Complexation

(2016) André J. van der Vlies et al.   BIOCONJUGATE CHEMISTRY

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

(2016) Zijian Zhou et al.   CHEMICAL SOCIETY REVIEWS

Use of fluorescent probes for ROS to tease apart Type I and Type II photochemical pathways in photodynamic therapy

(2016) Maria Garcia-Diaz et al.   METHODS

Dual-Stage-Light-Guided Tumor Inhibition by Mitochondria-Targeted Photodynamic Therapy

(2015) Kai Han et al.   ADVANCED FUNCTIONAL MATERIALS

A Tumor Targeted Chimeric Peptide for Synergistic Endosomal Escape and Therapy by Dual-Stage Light Manipulation

(2015) Kai Han et al.   ADVANCED FUNCTIONAL MATERIALS

Virus-Inspired Mimics Based on Dendritic Lipopeptides for Efficient Tumor-Specific Infection and Systemic Drug Delivery

(2015) Zhijun Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

NIR-Responsive On-Demand Release of CO from Metal Carbonyl-Caged Graphene Oxide Nanomedicine

(2015) Qianjun He et al.   ADVANCED MATERIALS

Bioinspired Therapeutic Dendrimers as Efficient Peptide Drugs Based on Supramolecular Interactions for Tumor Inhibition

(2015) Xiao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A photoCORM nanocarrier for CO release using NIR light

(2015) Agustin E. Pierri et al.   CHEMICAL COMMUNICATIONS

Biodegradable Polymer Nanogels for Drug/Nucleic Acid Delivery

(2015) Yulin Li et al.   CHEMICAL REVIEWS

Micro- and nanogels with labile crosslinks – from synthesis to biomedical applications

(2015) Xuejiao Zhang et al.   CHEMICAL SOCIETY REVIEWS

Rapid Eradication of Human Breast Cancer Cells through Trackable Light-Triggered CO Delivery by Mesoporous Silica Nanoparticles Packed with a Designed photoCORM

(2015) Indranil Chakraborty et al.   CHEMISTRY OF MATERIALS

Gasotransmitters in cancer: from pathophysiology to experimental therapy

(2015) Csaba Szabo   NATURE REVIEWS DRUG DISCOVERY

Design Strategies To Improve the Sensitivity of Photoactive Metal Carbonyl Complexes (photoCORMs) to Visible Light and Their Potential as CO-Donors to Biological Targets

(2014) Indranil Chakraborty et al.   ACCOUNTS OF CHEMICAL RESEARCH

pH-Responsive Cyanine-Grafted Graphene Oxide for Fluorescence Resonance Energy Transfer-Enhanced Photothermal Therapy

(2014) Miao Guo et al.   ADVANCED FUNCTIONAL MATERIALS

Carbon-Monoxide-Releasing Molecules for the Delivery of Therapeutic CO In Vivo

(2014) Sandra García-Gallego et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs)

(2014) U Schatzschneider   BRITISH JOURNAL OF PHARMACOLOGY

Carbon monoxide – physiology, detection and controlled release

(2014) Stefan H. Heinemann et al.   CHEMICAL COMMUNICATIONS

Antiproliferative effects of carbon monoxide on pancreatic cancer

(2014) Libor Vítek et al.   DIGESTIVE AND LIVER DISEASE

An Activatable Prodrug for the Treatment of Metastatic Tumors

(2014) Eun-Joong Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

(2013) B. Wegiel et al.   CANCER RESEARCH

The induction of heme oxygenase-1 suppresses heat shock protein 90 and the proliferation of human breast cancer cells through its byproduct carbon monoxide

(2013) Wen-Ying Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Developing drug molecules for therapy with carbon monoxide

(2012) Carlos C. Romão et al.   CHEMICAL SOCIETY REVIEWS

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

[Mn(CO)4{S2CNMe(CH2CO2H)}], a new water-soluble CO-releasing molecule

(2011) Sian H. Crook et al.   DALTON TRANSACTIONS

Dendrimer phthalocyanine-encapsulated polymeric micelle-mediated photochemical internalization extends the efficacy of photodynamic therapy and overcomes drug-resistance in vivo

(2011) Hsueh-Lin Lu et al.   JOURNAL OF CONTROLLED RELEASE

Beneficial effects of carbon monoxide-releasing molecule-2 (CORM-2) on acute doxorubicin cardiotoxicity in mice: Role of oxidative stress and apoptosis

(2011) Hitesh Soni et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Carbon Monoxide-Releasing Micelles for Immunotherapy

(2010) Urara Hasegawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY