Astrocytes sustain long-term productive HIV-1 infection without establishment of reactivable viral latency

Astrocyte-mediated synapse remodeling in the pathological brain

(2017) Sun Kwang Kim et al.   GLIA

Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents

(2017) Caroline Pereira Bittencourt Passaes et al.   JOURNAL OF VIROLOGY

Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells

(2017) David Alvarez-Carbonell et al.   Retrovirology

HIV Latency: Should We Shock or Lock?

(2017) Gilles Darcis et al.   TRENDS IN IMMUNOLOGY

HIV-1 Nef is released in extracellular vesicles derived from astrocytes: evidence for Nef-mediated neurotoxicity

(2017) A Sami Saribas et al.   Cell Death & Disease

Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material

(2017) Rebecca A. Russell et al.   Cell Reports

Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation

(2017) Alberto Bosque et al.   Cell Reports

Astrocytes as an HIV Reservoir: Mechanism of HIV Infection

(2016) Guan-Han Li et al.   CURRENT HIV RESEARCH

HIV-1 Latency and Eradication: Past, Present and Future

(2016) Prasun K. Datta et al.   CURRENT HIV RESEARCH

HIV-1 Tat Promotes Lysosomal Exocytosis in Astrocytes and Contributes to Astrocyte-mediated Tat Neurotoxicity

(2016) Yan Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toxicity and in vitro activity of HIV-1 latency-reversing agents in primary CNS cells

(2016) Lachlan R. Gray et al.   JOURNAL OF NEUROVIROLOGY

Defining the roles for Vpr in HIV-1-associated neuropathogenesis

(2016) Tony James et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment

(2016) Deanna Saylor et al.   Nature Reviews Neurology

Reversal of Latency as Part of a Cure for HIV-1

(2016) Thomas Aagaard Rasmussen et al.   TRENDS IN MICROBIOLOGY

Cell-to-cell contact facilitates HIV transmission from lymphocytes to astrocytes via CXCR4

(2015) Guan-Han Li et al.   AIDS

HIV-1 Tat Alters Neuronal Autophagy by Modulating Autophagosome Fusion to the Lysosome: Implications for HIV-Associated Neurocognitive Disorders

(2015) J. Fields et al.   JOURNAL OF NEUROSCIENCE

Enigma of HIV-1 latent infection in astrocytes: an in-vitro study using protein kinase C agonist as a latency reversing agent

(2015) Ashok Chauhan   MICROBES AND INFECTION

Bryostatin activates HIV-1 latent expression in human astrocytes through a PKC and NF-ĸB-dependent mechanism

(2015) Laura Díaz et al.   Scientific Reports

Cell–cell contact viral transfer contributes to HIV infection and persistence in astrocytes

(2014) Xiaoyu Luo et al.   JOURNAL OF NEUROVIROLOGY

HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research

(2014) Melissa J. Churchill et al.   JOURNAL OF NEUROVIROLOGY

Emergence of CD4 Independence Envelopes and Astrocyte Infection in R5 Simian-Human Immunodeficiency Virus Model of Encephalitis

(2014) K. Zhuang et al.   JOURNAL OF VIROLOGY

Unperturbed Posttranscriptional Regulatory Rev Protein Function and HIV-1 Replication in Astrocytes

(2014) Ashok Chauhan   PLoS One

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

(2014) John G Walsh et al.   Retrovirology

Endocytosis-mediated HIV-1 entry and its significance in the elusive behavior of the virus in astrocytes

(2014) Ashok Chauhan et al.   VIROLOGY

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

Epigenetic Regulation of HIV-1 Latency in Astrocytes

(2013) S. D. Narasipura et al.   JOURNAL OF VIROLOGY

A Doubly Fluorescent HIV-1 Reporter Shows that the Majority of Integrated HIV-1 Is Latent Shortly after Infection

(2013) M. S. Dahabieh et al.   JOURNAL OF VIROLOGY

Reactivation of latent HIV-1 in central memory CD4+ T cells through TLR-1/2 stimulation

(2013) Camille L Novis et al.   Retrovirology

Isolation and characterization of living primary astroglial cells using the new GLAST-specific monoclonal antibody ACSA-1

(2012) Melanie Jungblut et al.   GLIA

Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment

(2011) Jarek Harezlak et al.   AIDS

Brain Cell Reservoirs of Latent Virus in Presymptomatic HIV-Infected Individuals

(2011) Katherine A. Thompson et al.   AMERICAN JOURNAL OF PATHOLOGY

Screening for Cognitive Impairment in Human Immunodeficiency Virus

(2011) V. Valcour et al.   CLINICAL INFECTIOUS DISEASES

HIV-1 Tat Protein Promotes Neuronal Dysfunction through Disruption of MicroRNAs

(2011) J. Robert Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Immunodeficiency Virus Infection of Human Astrocytes Disrupts Blood-Brain Barrier Integrity by a Gap Junction-Dependent Mechanism

(2011) E. A. Eugenin et al.   JOURNAL OF NEUROSCIENCE

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp)

(2010) Michelle Vincendeau et al.   AIDS

Eradication of HIV from the brain: reasons for pause

(2010) Avindra Nath et al.   AIDS

Molecular mechanisms of neuroinvasion by monocytes-macrophages in HIV-1 infection

(2010) Gabriel Gras et al.   Retrovirology

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

(2009) Melissa J. Churchill et al.   ANNALS OF NEUROLOGY

TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4+ T cells

(2009) Sandra Thibault et al.   Retrovirology

Efficient magnetic bead-based separation of HIV-1-infected cells using an improved reporter virus system reveals that p53 up-regulation occurs exclusively in the virus-expressing cell population

(2009) Michaël Imbeault et al.   VIROLOGY

The HIV Envelope but Not VSV Glycoprotein Is Capable of Mediating HIV Latent Infection of Resting CD4 T Cells

(2009) Dongyang Yu et al.   PLoS Pathogens