HIV-1 reprograms the migration of macrophages

Podosomes are disrupted in PAPA syndrome

(2014) I. Maridonneau-Parini   BLOOD

The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages

(2014) T. W. Starnes et al.   BLOOD

An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages

(2014) Anthony Troegeler et al.   IMMUNOLOGY AND CELL BIOLOGY

Tyrosine Phosphorylation of Wiskott-Aldrich Syndrome Protein (WASP) by Hck Regulates Macrophage Function

(2014) Haein Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adding new dimensions: towards an integrative understanding of HIV-1 spread

(2014) Oliver T. Fackler et al.   NATURE REVIEWS MICROBIOLOGY

The cellular and molecular origin of tumor-associated macrophages

(2014) R. A. Franklin et al.   SCIENCE

The multiple faces of leukocyte interstitial migration

(2014) Tim Lämmermann et al.   Seminars in Immunopathology

Protrusion force microscopy reveals oscillatory force generation and mechanosensing activity of human macrophage podosomes

(2014) Anna Labernadie et al.   Nature Communications

Cyclin D1-Dependent Induction of Luminal Inflammatory Breast Tumors by Activated Notch3

(2013) H. Ling et al.   CANCER RESEARCH

Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents

(2013) Cristina Tintori et al.   ChemMedChem

Hck contributes to bone homeostasis by controlling the recruitment of osteoclast precursors

(2013) Christel Vérollet et al.   FASEB JOURNAL

Mucosal immunology of HIV infection

(2013) Huanbin Xu et al.   IMMUNOLOGICAL REVIEWS

A specific subset of RabGTPases controls cell surface exposure of MT1-MMP, extracellular matrix degradation and three-dimensional invasion of macrophages

(2013) C. Wiesner et al.   JOURNAL OF CELL SCIENCE

Macrophages Accumulate in the Gut Mucosa of Untreated HIV-infected Patients

(2013) K. Allers et al.   JOURNAL OF INFECTIOUS DISEASES

The HIV-1-containing macrophage compartment: a perfect cellular niche?

(2013) Joshua Tan et al.   TRENDS IN MICROBIOLOGY

Kinetics of liver macrophages (Kupffer cells) in SIV-infected macaques

(2013) Muhammad H. Ahsan et al.   VIROLOGY

Interplay between myosin IIA-mediated contractility and actin network integrity orchestrates podosome composition and oscillations

(2013) K. van den Dries et al.   Nature Communications

WIP: WASP-interacting proteins at invadopodia and podosomes

(2012) Esther García et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments

(2012) Céline Cougoule et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Three-dimensional invasion of macrophages is mediated by cysteine cathepsins in protrusive podosomes

(2012) Zala Jevnikar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophage Mesenchymal Migration Requires Podosome Stabilization by Filamin A

(2012) Romain Guiet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-Domain Antibody-SH3 Fusions for Efficient Neutralization of HIV-1 Nef Functions

(2012) J. Bouchet et al.   JOURNAL OF VIROLOGY

HIV-infected T cells are migratory vehicles for viral dissemination

(2012) Thomas T. Murooka et al.   NATURE

New dimensions in cell migration

(2012) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo

(2012) B. Stolp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling

(2011) X. Pan et al.   BLOOD

Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody

(2011) J. Bouchet et al.   BLOOD

Interactions of the HIV/SIV Pathogenicity Factor Nef with SH3 Domain-Containing Host Cell Proteins

(2011) Kalle Saksela   CURRENT HIV RESEARCH

Impaired podosome formation and invasive migration of macrophages from patients with a PSTPIP1 mutation and PAPA syndrome

(2010) Christa L. Cortesio et al.   ARTHRITIS AND RHEUMATISM

KIF5B and KIF3A/KIF3B kinesins drive MT1-MMP surface exposure, CD44 shedding, and extracellular matrix degradation in primary macrophages

(2010) C. Wiesner et al.   BLOOD

Inhibition of phagocytosis in HIV-1-infected macrophages relies on Nef-dependent alteration of focal delivery of recycling compartments

(2010) J. Mazzolini et al.   BLOOD

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Cancer Dissemination—Lessons from Leukocytes

(2010) Chris D. Madsen et al.   DEVELOPMENTAL CELL

Macrophage podosomes go 3D

(2010) Emeline Van Goethem et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

HIV-1 Nef Disrupts Maturation of CD4+ T Cells through CD4/Lck Modulation

(2010) P. Chrobak et al.   JOURNAL OF IMMUNOLOGY

HIV-1 Nef Triggers Macrophage Fusion in a p61Hck- and Protease-Dependent Manner

(2010) C. Verollet et al.   JOURNAL OF IMMUNOLOGY

Lentiviral Nef Proteins Utilize PAK2-Mediated Deregulation of Cofilin as a General Strategy To Interfere with Actin Remodeling

(2010) B. Stolp et al.   JOURNAL OF VIROLOGY

Dynamics of podosome stiffness revealed by atomic force microscopy

(2010) A. Labernadie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis

(2009) C. Cougoule et al.   BLOOD

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

HIV-1 Nef Interferes with Host Cell Motility by Deregulation of Cofilin

(2009) Bettina Stolp et al.   Cell Host & Microbe

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages

(2009) A. Dovas et al.   JOURNAL OF CELL SCIENCE

Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures

(2009) E. Van Goethem et al.   JOURNAL OF IMMUNOLOGY

HIV-1 Nef-mediated inhibition of T cell migration and its molecular determinants

(2009) In-Woo Park et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Selective Expression of Human Immunodeficiency Virus Nef in Specific Immune Cell Populations of Transgenic Mice Is Associated with Distinct AIDS-Like Phenotypes

(2009) Z. Hanna et al.   JOURNAL OF VIROLOGY

HIV-1 Nef Inhibits Ruffles, Induces Filopodia, and Modulates Migration of Infected Lymphocytes

(2009) C. Nobile et al.   JOURNAL OF VIROLOGY

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

(2009) Weifeng Xu et al.   NATURE IMMUNOLOGY

Molecular mediators of macrophage fusion

(2009) Laura Helming et al.   TRENDS IN CELL BIOLOGY

Cell Biology of HIV-1 Infection of Macrophages

(2008) Carol A. Carter et al.   Annual Review of Microbiology

The oncogenic activity of the Src family kinase Hck requires the cooperative action of the plasma membrane- and lysosome-associated isoforms

(2008) Renaud Poincloux et al.   EUROPEAN JOURNAL OF CANCER

Human Immunodeficiency Virus Type 1 Nef Incorporation into Virions Does Not Increase Infectivity

(2008) N. Laguette et al.   JOURNAL OF VIROLOGY

Interstitial leukocyte migration and immune function

(2008) Peter Friedl et al.   NATURE IMMUNOLOGY

Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBP 

(2008) I. Komuro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 Nef: at the crossroads

(2008) John L Foster et al.   Retrovirology

The Tyrosine Kinase Activity of c-Src Regulates Actin Dynamics and Organization of Podosomes in Osteoclasts

(2007) Olivier Destaing et al.   MOLECULAR BIOLOGY OF THE CELL