B Vitamins and Fatty Acids: What Do They Share with Small Vessel Disease-Related Dementia?

The Controversial Role of Homocysteine in Neurology: From Labs to Clinical Practice

(2019) Rita Moretti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Longitudinal analysis on determinants of vitamin B6 status in community-dwelling older adults over a period of 18 years

(2019) Alexandra Jungert et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Randomized Trial of Marine n-3 Polyunsaturated Fatty Acids for the Prevention of Cerebral Small Vessel Disease and Inflammation in Aging (PUFA Trial): Rationale, Design and Baseline Results

(2019) Gene Bowman et al.   Nutrients

Inborn errors of coenzyme A metabolism and neurodegeneration

(2019) Ivano Di Meo et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Disorders affecting vitamin B 6 metabolism

(2019) Matthew P. Wilson et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Vitamin B12 , folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation

(2019) D. Sean Froese et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications

(2019) Valeria Gasperi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitigating effect of biotin against irradiation-induced cerebral cortical and hippocampal damage in the rat brain tissue

(2019) Nadia Abdel-Magied et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Role of endothelial NAD+ deficiency in age-related vascular dysfunction

(2019) Anna Csicsar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Lower Plasma Vitamin B-6 is Associated with 2-Year Cognitive Decline in the Boston Puerto Rican Health Study

(2019) Natalia Palacios et al.   JOURNAL OF NUTRITION

Associations of Dietary Riboflavin, Niacin, and Retinol with Age-related Hearing Loss: An Analysis of Korean National Health and Nutrition Examination Survey Data

(2019) Tae Su Kim et al.   Nutrients

Intellectual Disability Associated With Pyridoxine-Responsive Epilepsies: The Need to Protect Cognitive Development

(2019) Bjørnar Hassel et al.   Frontiers in Psychiatry

Associations of dietary choline intake with risk of incident dementia and with cognitive performance: the Kuopio Ischaemic Heart Disease Risk Factor Study

(2019) Maija P T Ylilauri et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington’s Disease

(2019) Stefano Patassini et al.   Metabolites

Royal Jelly and Its Components Promote Healthy Aging and Longevity: From Animal Models to Humans

(2019) Kunugi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dietary Intake of Riboflavin and Unsaturated Fatty Acid Can Improve the Multi-Domain Cognitive Function in Middle-Aged and Elderly Populations: A 2-Year Prospective Cohort Study

(2019) Lingwei Tao et al.   Frontiers in Aging Neuroscience

Origin and pathophysiology of protein carbonylation, nitration and chlorination in age-related brain diseases and aging

(2018) Efstathios S. Gonos et al.   Aging-US

Prevention of progression in Parkinson’s disease

(2018) Jan Aaseth et al.   BIOMETALS

Thiamine for preventing dementia development among patients with alcohol use disorder: A nationwide population-based cohort study

(2018) Wei-Po Chou et al.   CLINICAL NUTRITION

Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models

(2018) Daniel Elbaum et al.   PLoS One

NAD+supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

(2018) Yujun Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enriched Brain Omega-3 Polyunsaturated Fatty Acids Confer Neuroprotection against Microinfarction

(2018) Chuanming Luo et al.   EBioMedicine

Plasma pyridoxal 5′-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003–2004

(2018) Martha Savaria Morris et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Food for Thought: Souvenaid® in Mild Alzheimer's Disease

(2018) Jeffrey L. Cummings   JOURNAL OF ALZHEIMERS DISEASE

Efficacy of Souvenaid in Mild Alzheimer's Disease: Results from a Randomized, Controlled Trial

(2018) Philip Scheltens et al.   JOURNAL OF ALZHEIMERS DISEASE

High methionine, low folate and low vitamin B6/B12 (HM-LF-LV) diet causes neurodegeneration and subsequent short-term memory loss

(2018) Mohammed Nuru et al.   METABOLIC BRAIN DISEASE

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

(2018) Xuchu Que et al.   NATURE

Decline in Sirtuin-1 expression and activity plays a critical role in blood-brain barrier permeability in aging

(2018) Svetlana M. Stamatovic et al.   NEUROBIOLOGY OF DISEASE

The chemistry of the vitamin B3 metabolome

(2018) Mikhail V. Makarov et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Riboflavin and pyridoxine restore dopamine levels and reduce oxidative stress in brain of rats

(2018) Armando Valenzuela Peraza et al.   BMC NEUROSCIENCE

The Role of NADPH Oxidases and Oxidative Stress in Neurodegenerative Disorders

(2018) Anuradha Tarafdar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nicotinamide ribose ameliorates cognitive impairment of aged and Alzheimer’s disease model mice

(2018) Xian Xie et al.   METABOLIC BRAIN DISEASE

The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial

(2018) Talitha Ford et al.   Nutrients

Brain SIRT1 Mediates Metabolic Homeostasis and Neuroprotection

(2018) Jing Xu et al.   Frontiers in Endocrinology

Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration

(2017) Pauline Vaur et al.   FASEB JOURNAL

Prophylaxis of migraine headaches with riboflavin: A systematic review

(2017) D. F. Thompson et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Vitamin B12 and homocysteine associations with gait speed in older adults: The Baltimore Longitudinal Study of Aging

(2017) M. L. Vidoni et al.   Journal of Nutrition Health & Aging

B vitamins and cognition in subjects with small vessel disease: A Substudy of VITATOPS, a randomized, placebo-controlled trial

(2017) Simon Kang Seng Ting et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neuroprotective potential of high-dose biotin

(2017) Mark F. McCarty et al.   MEDICAL HYPOTHESES

Inflammation, vitamin B6 and related pathways

(2017) Per Magne Ueland et al.   MOLECULAR ASPECTS OF MEDICINE

Dynamic association of epigenetic H3K4me3 and DNA 5hmC marks in the dorsal hippocampus and anterior cingulate cortex following reactivation of a fear memory

(2017) William M. Webb et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

(2017) Costantino Iadecola   NEURON

The long-term relationship between dietary pantothenic acid (vitamin B 5 ) intake and C-reactive protein concentration in adults aged 40 years and older

(2017) S. Jung et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Neuroprotective Actions of Dietary Choline

(2017) et al.   Nutrients

A Complex Interplay of Vitamin B1 and B6 Metabolism with Cognition, Brain Structure, and Functional Connectivity in Older Adults

(2017) Kai Jannusch et al.   Frontiers in Neuroscience

High dose biotin as treatment for progressive multiple sclerosis

(2017) Gary Birnbaum et al.   Multiple Sclerosis and Related Disorders

Riboflavin Has Neuroprotective Potential: Focus on Parkinson’s Disease and Migraine

(2017) Eyad T. Marashly et al.   Frontiers in Neurology

Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

(2017) Annika Höhn et al.   Redox Biology

Riboflavin Responsive Mitochondrial Dysfunction in Neurodegenerative Diseases

(2017) Tamilarasan Udhayabanu et al.   Journal of Clinical Medicine

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

(2016) Natalie E. de Picciotto et al.   AGING CELL

High dietary advanced glycation end products are associated with poorer spatial learning and accelerated Aβ deposition in an Alzheimer mouse model

(2016) Irit Lubitz et al.   AGING CELL

Vitamin B-12 status and neurologic function in older people: a cross-sectional analysis of baseline trial data from the Older People and Enhanced Neurological Function (OPEN) study

(2016) Lisa M Miles et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Vitamin B1 (thiamine) and dementia

(2016) Gary E. Gibson et al.   Annals of the New York Academy of Sciences

Homocysteine, B Vitamins, and Cognitive Impairment

(2016) A. David Smith et al.   Annual Review of Nutrition

Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID)

(2016) Atticus H. Hainsworth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Riboflavin and health: A review of recent human research

(2016) Kiran Thakur et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The Effects of Vitamin B in Depression

(2016) Kathleen Mikkelsen et al.   CURRENT MEDICINAL CHEMISTRY

Energy metabolism and inflammation in brain aging and Alzheimer’s disease

(2016) Fei Yin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Association of Serum Vitamin D with the Risk of Incident Dementia and Subclinical Indices of Brain Aging: The Framingham Heart Study

(2016) Ioannis Karakis et al.   JOURNAL OF ALZHEIMERS DISEASE

SIRT1 in Endothelial Cells as a Novel Target for the Prevention of Early Vascular Aging

(2016) Yumeng Guo et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Integrity of normal-appearing white matter: Influence of age, visible lesion burden and hypertension in patients with small-vessel disease

(2016) Susana Muñoz Maniega et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Efficacy of Vitamin B Supplementation on Cognition in Elderly Patients With Cognitive-Related Diseases

(2016) Dong-Mei Zhang et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Nicotinamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy

(2016) Deborah A. Shear et al.   JOURNAL OF NEUROTRAUMA

MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study

(2016) Ayman Tourbah et al.   Multiple Sclerosis Journal

Nicotinamide mononucleotide inhibits post-ischemic NAD+ degradation and dramatically ameliorates brain damage following global cerebral ischemia

(2016) Ji H. Park et al.   NEUROBIOLOGY OF DISEASE

Knock-down of pantothenate kinase 2 severely affects the development of the nervous and vascular system in zebrafish, providing new insights into PKAN disease

(2016) Daniela Zizioli et al.   NEUROBIOLOGY OF DISEASE

Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis

(2016) Frédéric Sedel et al.   NEUROPHARMACOLOGY

Mechanisms Responsible for the High Sensitivity of Neural Cells to Vitamin B1 Deficiency

(2016) Yu. M. Parkhomenko et al.   NEUROPHYSIOLOGY

Role of folic acid in nitric oxide bioavailability and vascular endothelial function

(2016) Anna E. Stanhewicz et al.   NUTRITION REVIEWS

Hyperhomocysteinemia impairs regional blood flow: involvements of endothelial and neuronal nitric oxide

(2016) Noboru Toda et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Causes, Consequences and Public Health Implications of Low B-Vitamin Status in Ageing

(2016) Kirsty Porter et al.   Nutrients

B Vitamins and the Brain: Mechanisms, Dose and Efficacy—A Review

(2016) David Kennedy   Nutrients

Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function

(2016) Andrew J. Kennedy et al.   Cell Reports

Neural Correlates for Apathy: Frontal-Prefrontal and Parietal Cortical- Subcortical Circuits

(2016) Rita Moretti et al.   Frontiers in Aging Neuroscience

MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study

(2016) Ayman Tourbah et al.   Multiple Sclerosis Journal

Enhancing NAD+salvage metabolism is neuroprotective in a PINK1 model of Parkinson's disease

(2016) Susann Lehmann et al.   Biology Open

Update on cerebral small vessel disease: a dynamic whole-brain disease

(2016) Yulu Shi et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Measurement of Blood Thiamine Metabolites for Alzheimer's Disease Diagnosis

(2016) Xiaoli Pan et al.   EBioMedicine

Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI

(2016) Fei Ma et al.   Scientific Reports

HMGB1 Inhibition During Zymosan-Induced Inflammation: The Potential Therapeutic Action of Riboflavin

(2015) Agnieszka Irena Mazur-Bialy et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Cerebral microvascular pericytes and neurogliovascular signaling in health and disease

(2015) Turgay Dalkara et al.   BRAIN RESEARCH

Micronutrient intakes and potential inadequacies of community-dwelling older adults: a systematic review

(2015) Sovianne ter Borg et al.   BRITISH JOURNAL OF NUTRITION

Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter

(2015) Jiao-Jiao Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Longitudinal change of small-vessel disease-related brain abnormalities

(2015) Reinhold Schmidt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Major involvement of Na+-dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells

(2015) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Biomarkers of Nutrition for Development—Folate Review

(2015) Lynn B Bailey et al.   JOURNAL OF NUTRITION

Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome

(2015) Alicia Guemez-Gamboa et al.   NATURE GENETICS

Longitudinal Relationship Between Cerebral Small-Vessel Disease and Cerebral Blood Flow: The Second Manifestations of Arterial Disease-Magnetic Resonance Study

(2015) P. H. van der Veen et al.   STROKE

Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

(2015) Christian T. Madsen et al.   Nature Communications

Associations between B Vitamins and Parkinson’s Disease

(2015) Liang Shen   Nutrients

Niacin alleviates TRAIL-mediated colon cancer cell death via autophagy flux activation

(2015) Sung-Wook Kim et al.   Oncotarget

Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis

(2015) Garik Mkrtchyan et al.   Scientific Reports

Vitamin B-6

(2015) Patrick J Stover et al.   Advances in Nutrition

Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer’s disease

(2015) Anne Rijpma et al.   Alzheimers Research & Therapy

The Association between Cerebral White Matter Lesions and Plasma Omega-3 to Omega-6 Polyunsaturated Fatty Acids Ratio to Cognitive Impairment Development

(2015) Michihiro Suwa et al.   Biomed Research International

Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer’s Disease

(2015) Massimo S. Fiandaca et al.   Frontiers in Neurology

Association between intake of B vitamins and cognitive function in elderly Koreans with cognitive impairment

(2015) Hyesook Kim et al.   Nutrition Journal

Biotin-Responsive Basal Ganglia Disease: Neuroimaging Features before and after Treatment

(2014) H. Kassem et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Homocysteine induces the expression of C-reactive protein via NMDAr-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells

(2014) Xiaoming Pang et al.   ATHEROSCLEROSIS

Thiamine deficiency results in release of soluble factors that disrupt mitochondrial membrane potential and downregulate the glutamate transporter splice-variant GLT-1b in cultured astrocytes

(2014) Shivraj S. Jhala et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Defective pantothenate metabolism and neurodegeneration

(2014) Susan J. Hayflick   BIOCHEMICAL SOCIETY TRANSACTIONS

Alteration of the coenzyme A biosynthetic pathway in neurodegeneration with brain iron accumulation syndromes: Table 1

(2014) Paola Venco et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Beyond BMI: The “Metabolically healthy obese” phenotype & its association with clinical/subclinical cardiovascular disease and all-cause mortality -- a systematic review

(2014) Lara L Roberson et al.   BMC PUBLIC HEALTH

Riboflavin (vitamin B2) and oxidative stress: a review

(2014) Marziyeh Ashoori et al.   BRITISH JOURNAL OF NUTRITION

Endothelial Dysfunction: The Link Between Homocysteine and Hydrogen Sulfide

(2014) Sathnur Pushpakumar et al.   CURRENT MEDICINAL CHEMISTRY

Vitamin B6 prevents cognitive impairment in experimental pneumococcal meningitis

(2014) Tatiana Barichello et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Riboflavin (vitamin B-2) reduces hepatocellular injury following liver ischaemia and reperfusion in mice

(2014) Sheila Cristina Sanches et al.   FOOD AND CHEMICAL TOXICOLOGY

Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C 677 T mutation and sickle cell trait without homocysteinemia: An autopsy case report and review of literature

(2014) Z. Ali et al.   FORENSIC SCIENCE INTERNATIONAL

Hyperhomocysteinemia and Neurologic Disorders: a Review

(2014) Ramin Ansari et al.   Journal of Clinical Neurology

Combination of metabolomic and phospholipid-profiling approaches for the study of Alzheimer's disease

(2014) Raúl González-Domínguez et al.   Journal of Proteomics

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

(2014) Long N. Nguyen et al.   NATURE

Critical levels of brain atrophy associated with homocysteine and cognitive decline

(2014) Celeste A. de Jager   NEUROBIOLOGY OF AGING

microRNAs: A connection between cholesterol metabolism and neurodegeneration

(2014) Leigh Goedeke et al.   NEUROBIOLOGY OF DISEASE

Toxic Effects of Mildly Elevated Homocysteine Concentrations in Neuronal-Like Cells

(2014) M. Currò et al.   NEUROCHEMICAL RESEARCH

NF-κB activation and cell death after intracerebral hemorrhage in patients

(2014) Zeli Zhang et al.   NEUROLOGICAL SCIENCES

Glutamate Carboxypeptidase II Inhibition Behaviorally and Physiologically Improves Pyridoxine-Induced Neuropathy in Rats

(2014) Michelle C. Potter et al.   PLoS One

DHA-PC and PSD-95 decrease after loss of synaptophysin and before neuronal loss in patients with Alzheimer's disease

(2014) Dai Yuki et al.   Scientific Reports

Epigenetic Modifications: Basic Mechanisms and Role in Cardiovascular Disease (2013 Grover Conference Series)

(2014) Joseph Loscalzo et al.   Pulmonary Circulation

NADPH Oxidases in Vascular Pathology

(2013) Anna Konior et al.   ANTIOXIDANTS & REDOX SIGNALING

Phospholipid methylation in mammals: from biochemistry to physiological function

(2013) Dennis E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Vitamin B6 reduces hippocampal apoptosis in experimental pneumococcal meningitis

(2013) Denise C Zysset-Burri et al.   BMC INFECTIOUS DISEASES

Microvascular dysfunction as a link between obesity, insulin resistance and hypertension

(2013) Ü. Karaca et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Thiamin-dependent enzymes: new perspectives from the interface between chemistry and biology

(2013) Victoria I. Bunik   FEBS Journal

Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Aβ(1–42)-induced rat model of Alzheimer's disease

(2013) E. Turunc Bayrakdar et al.   FREE RADICAL RESEARCH

Induction of Hyperhomocysteinemia Models Vascular Dementia by Induction of Cerebral Microhemorrhages and Neuroinflammation

(2013) Tiffany L Sudduth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

(2013) Bing Gong et al.   NEUROBIOLOGY OF AGING

Nicotinamide pre-treatment ameliorates NAD(H) hyperoxidation and improves neuronal function after severe hypoxia

(2013) Pavan K. Shetty et al.   NEUROBIOLOGY OF DISEASE

Acetyl-CoA the Key Factor for Survival or Death of Cholinergic Neurons in Course of Neurodegenerative Diseases

(2013) Andrzej Szutowicz et al.   NEUROCHEMICAL RESEARCH

Identification of Altered Metabolic Pathways in Plasma and CSF in Mild Cognitive Impairment and Alzheimer’s Disease Using Metabolomics

(2013) Eugenia Trushina et al.   PLoS One

Vitamin B12 and Progression of White Matter Lesions. A 2-Year Follow-Up Study in First-Ever Lacunar Stroke Patients

(2013) Ellen C. van Overbeek et al.   PLoS One

Effect of B Vitamins and Lowering Homocysteine on Cognitive Impairment in Patients With Previous Stroke or Transient Ischemic Attack: A Prespecified Secondary Analysis of a Randomized, Placebo-Controlled Trial and Meta-Analysis

(2013) G. J. Hankey et al.   STROKE

Pathology and pathogenesis of vascular cognitive impairment—a critical update

(2013) Kurt A. Jellinger   Frontiers in Aging Neuroscience

The Discovery of Niacin, Biotin, and Pantothenic Acid

(2012) Douglas J. Lanska   ANNALS OF NUTRITION AND METABOLISM

Review of Cerebral Microangiopathy and Alzheimer’s Disease: Relation between White Matter Hyperintensities and Microbleeds

(2012) C. Hommet et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Low and high homocysteine are associated with mortality independent of B group vitamins but interactive with cognitive status in a free-living elderly cohort

(2012) Li-Li Xiu et al.   NUTRITION RESEARCH

New Considerations on the Neuromodulatory Role of Thiamine

(2012) Joseph A. Hirsch et al.   PHARMACOLOGY

B Vitamins and Magnetic Resonance Imaging–Detected Ischemic Brain Lesions in Patients With Recent Transient Ischemic Attack or Stroke

(2012) Margherita Cavalieri et al.   STROKE

The Role of B Vitamins in Preventing and Treating Cognitive Impairment and Decline

(2012) Martha Savaria Morris   Advances in Nutrition

Heterogeneity in age-related white matter changes

(2011) Reinhold Schmidt et al.   ACTA NEUROPATHOLOGICA

Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans

(2011) Kerry-Ann da Costa et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Microinfarcts, brain atrophy, and cognitive function: The Honolulu Asia Aging Study Autopsy Study

(2011) Lenore J. Launer et al.   ANNALS OF NEUROLOGY

Continuous nicotinamide administration improves behavioral recovery and reduces lesion size following bilateral frontal controlled cortical impact injury

(2011) Cole Vonder Haar et al.   BEHAVIOURAL BRAIN RESEARCH

Vitamin B6: a challenging link between nutrition and inflammation in CVD

(2011) Valentina Lotto et al.   BRITISH JOURNAL OF NUTRITION

Pyridoxine inhibits endothelial NOS uncoupling induced by oxidized low-density lipoprotein via the PKCα signalling pathway in human umbilical vein endothelial cells

(2011) Liping Xie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression

(2011) Karen D. Corbin et al.   CURRENT OPINION IN GASTROENTEROLOGY

Antioxidant and B vitamin intake in relation to cognitive function in later life in the Lothian Birth Cohort 1936

(2011) G McNeill et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Magnetic Resonance Imaging in Cerebral Small Vessel Disease and its Use as a Surrogate Disease Marker

(2011) Bhavini Patel et al.   International Journal of Stroke

Hypothesis: Hyperhomocysteinemia is an indicator of oxidant stress

(2011) Maureane Hoffman   MEDICAL HYPOTHESES

Cerebral subcortical small vessel disease and its relation to cognition in elderly subjects: a pathological study in the Oxford Project to Investigate Memory and Ageing (OPTIMA) cohort

(2011) A. Smallwood et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Use of folic acid and vitamin supplementation among adults with depression and anxiety: a cross-sectional, population-based survey

(2011) Guixiang Zhao et al.   Nutrition Journal

Efficacy of a medical food in mild Alzheimer's disease: A randomized, controlled trial

(2010) Philip Scheltens et al.   Alzheimers & Dementia

Powerful beneficial effects of benfotiamine on cognitive impairment and  -amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice

(2010) X. Pan et al.   BRAIN

Dietary intake of folate, vitamin B6, vitamin B12 and riboflavin and risk of Parkinson's disease: a case–control study in Japan

(2010) Kentaro Murakami et al.   BRITISH JOURNAL OF NUTRITION

Vitamin B6 Compounds are Capable of Reducing the Superoxide Radical and Lipid Peroxide Levels Induced by H2O2 in Vascular Endothelial Cells in Culture

(2010) Mohamedain M. Mahfouz et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Dynamics of Regional Distribution of Ischemic Lesions in Middle Cerebral Artery Trunk Occlusion Relates to Collateral Circulation

(2010) Bastian Cheng et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects

(2010) Henk J. Blom et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo

(2010) Christopher J. Pynn et al.   JOURNAL OF LIPID RESEARCH

Dietary folate, vitamin B-12, vitamin B-6 and incident Alzheimer’s disease: The cache county memory, health, and aging study

(2010) C. Nelson et al.   Journal of Nutrition Health & Aging

B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial

(2010)   LANCET NEUROLOGY

Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges

(2010) Leonardo Pantoni   LANCET NEUROLOGY

Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake

(2010) Eri Suzuki et al.   LIFE SCIENCES

Pyridoxine Restores Endothelial Cell Function in High Glucose

(2010) Bret G. Kelso et al.   Metabolic Syndrome and Related Disorders

Unknown

(2010) Martin Ploder et al.   MOLECULAR MEDICINE

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease

(2010) Tyisha Hathorn et al.   NEUROBIOLOGY OF DISEASE

Quantitative analysis of hemodynamic and metabolic changes in subcortical vascular dementia using simultaneous near-infrared spectroscopy and fMRI measurements

(2010) Sungho Tak et al.   NEUROIMAGE

Diabetes, Alzheimer disease, and vascular dementia: A population-based neuropathologic study

(2010) S. Ahtiluoto et al.   NEUROLOGY

Riboflavin Can Protect Tissues from Oxidative Injury

(2010)   NUTRITION REVIEWS

Vitamin B6 and Immune Competence

(2010) Laura C. Rail et al.   NUTRITION REVIEWS

Sustained Delivery of Nicotinamide Limits Cortical Injury and Improves Functional Recovery Following Traumatic Brain Injury

(2010) Andrea M. Goffus et al.   Oxidative Medicine and Cellular Longevity

Gait in Elderly With Cerebral Small Vessel Disease

(2010) Karlijn F. de Laat et al.   STROKE

Citicoline in Vascular Cognitive Impairment and Vascular Dementia After Stroke

(2010) J. Alvarez-Sabin et al.   STROKE

Vitamin B-12 and homocysteine status among vegetarians: a global perspective

(2009) Ibrahim Elmadfa et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Biotin

(2009) Janos Zempleni et al.   BIOFACTORS

Folic acid, methylation and neural tube closure in humans

(2009) Henk J. Blom   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Thiaminylated adenine nucleotides. Chemical synthesis, structural characterization and natural occurrence

(2009) Michel Frédérich et al.   FEBS Journal

Vitamin B-6 Intake Is Inversely Related to, and the Requirement Is Affected by, Inflammation Status

(2009) Martha Savaria Morris et al.   JOURNAL OF NUTRITION

Age-associated leukoaraiosis and cortical cholinergic deafferentation

(2009) N. I. Bohnen et al.   NEUROLOGY

Vitamin B2 inhibits glutamate release from rat cerebrocortical nerve terminals

(2009) Su-Jane Wang et al.   NEUROREPORT

Molecular Genetics of Alcohol-Related Brain Damage

(2008) I. Guerrini et al.   ALCOHOL AND ALCOHOLISM

Greater intake of vitamins B6 and B12 spares gray matter in healthy elderly: A voxel-based morphometry study

(2008) Kirk I. Erickson et al.   BRAIN RESEARCH

Prenatal choline supplementation in rats increases the expression of IGF2 and its receptor IGF2R and enhances IGF2-induced acetylcholine release in hippocampus and frontal cortex

(2008) Isabella Napoli et al.   BRAIN RESEARCH

Antihypertensive effect of biotin in stroke-prone spontaneously hypertensive rats

(2008) Mari Watanabe-Kamiyama et al.   BRITISH JOURNAL OF NUTRITION

Alcohol-related dementia: a 21st-century silent epidemic?

(2008) Susham Gupta et al.   BRITISH JOURNAL OF PSYCHIATRY

Homocysteine Inhibits Arterial Endothelial Cell Growth Through Transcriptional Downregulation of Fibroblast Growth Factor-2 Involving G Protein and DNA Methylation

(2008) Po-Yuan Chang et al.   CIRCULATION RESEARCH

Dynamic changes in DNA methylation during thermal control establishment affect CREB binding to the brain-derived neurotrophic factor promoter

(2008) Maya Yossifoff et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease

(2008) Paul S. Aisen   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Homocysteine Reduces Endothelial Progenitor Cells in Stroke Patients through Apoptosis

(2008) Mohammad Murshedul Alam et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Epigenetic Regulation of bdnf Gene Transcription in the Consolidation of Fear Memory

(2008) F. D. Lubin et al.   JOURNAL OF NEUROSCIENCE

Age-Related Alterations of B-Group Vitamin Contents in Urine, Blood and Liver from Rats

(2008) Tsutomu FUKUWATARI et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Combined effects of niacin and chromium treatment on vascular endothelial dysfunction in hyperlipidemic rats

(2008) N. Niu et al.   MOLECULAR BIOLOGY REPORTS

Homocysteine and Its Relationship to Stroke Subtypes in a UK Black Population

(2008) Usman Khan et al.   STROKE

Progression of White Matter Hyperintensities and Incidence of New Lacunes Over a 3-Year Period

(2008) Alida A. Gouw et al.   STROKE

Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes

(2007) Claudia A. Benavente et al.   FREE RADICAL BIOLOGY AND MEDICINE