Nicotinamide ribose ameliorates cognitive impairment of aged and Alzheimer’s disease model mice

Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes

(2018) Nady Braidy et al.   ANTIOXIDANTS & REDOX SIGNALING

NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

(2018) Jun Yoshino et al.   Cell Metabolism

Drug development for Alzheimer’s disease: review

(2018) Kejing Lao et al.   JOURNAL OF DRUG TARGETING

Targeting NAD + degradation: The therapeutic potential of flavonoids for Alzheimer's disease and cognitive frailty

(2018) Qingwei Ruan et al.   PHARMACOLOGICAL RESEARCH

Mild cognitive impairment due to Alzheimer disease: Contemporary approaches to diagnostics and pharmacological intervention

(2018) Sergey O. Bachurin et al.   PHARMACOLOGICAL RESEARCH

NAD+supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

(2018) Yujun Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

(2018) Christopher R. Martens et al.   Nature Communications

Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration

(2017) Pauline Vaur et al.   FASEB JOURNAL

Why do so many clinical trials of therapies for Alzheimer's disease fail?

(2017) Roy M Anderson et al.   LANCET

Alzheimer's disease and other dementias: update on research

(2017) Lon Schneider   LANCET NEUROLOGY

The NAD+/PARP1/SIRT1 Axis in Aging

(2017) Andrew R. Mendelsohn et al.   REJUVENATION RESEARCH

WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation

(2017) Dahu Li et al.   Neuroscience Bulletin

NAMPT serum levels are selectively elevated in acute infectious disease and in acute relapse of chronic inflammatory diseases in children

(2017) Julia Gesing et al.   PLoS One

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

(2016) Natalie E. de Picciotto et al.   AGING CELL

Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death

(2016) Xiaonan Wang et al.   BRAIN RESEARCH

Hepatic NAD+deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing

(2016) Can-Can Zhou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Weight Loss Is Associated With Increased NAD+/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue

(2016) Elisabeth Rappou et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk

(2016) S. A. Trammell et al.   JOURNAL OF NUTRITION

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

(2016) H. Zhang et al.   SCIENCE

NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation

(2016) D. Ryu et al.   Science Translational Medicine

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

(2016) Samuel A. J. Trammell et al.   Nature Communications

Toll-Like Receptor 4 Deficiency Causes Reduced Exploratory Behavior in Mice Under Approach-Avoidance Conflict

(2016) Chunlu Li et al.   Neuroscience Bulletin

TNP-ATP is Beneficial for Treatment of Neonatal Hypoxia-Induced Hypomyelination and Cognitive Decline

(2016) Jie Xiao et al.   Neuroscience Bulletin

Opposite Sex Contact and Isolation: A Novel Depression/Anxiety Model

(2016) Liu Yang et al.   Neuroscience Bulletin

Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer’s disease-relevant murine model

(2015) Aaron N Long et al.   BMC Neurology

Nicotinamide Phosphoribosyltransferase as a Target in Inflammation- Related Disorders

(2015) Fabrizio Montecucco et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

(2014) M Di Stefano et al.   CELL DEATH AND DIFFERENTIATION

Effects of Anethole in Nociception Experimental Models

(2014) Alessandra Mileni Versuti Ritter et al.   Evidence-based Complementary and Alternative Medicine

NAD+metabolism: A therapeutic target for age-related metabolic disease

(2013) Laurent Mouchiroud et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

(2013) Bing Gong et al.   NEUROBIOLOGY OF AGING

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

(2012) Carles Cantó et al.   Cell Metabolism

Secretome Analyses of Aβ1–42 Stimulated Hippocampal Astrocytes Reveal that CXCL10 is Involved in Astrocyte Migration

(2012) Wenjia Lai et al.   JOURNAL OF PROTEOME RESEARCH

Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession

(2012) Dong Liu et al.   NEUROBIOLOGY OF AGING

Pre-B Cell Colony Enhancing Factor/NAMPT/Visfatin in Inflammation and Obesity- Related Disorders

(2010) Alexander R. Moschen et al.   CURRENT PHARMACEUTICAL DESIGN

Early temporal short-term memory deficits in double transgenic APP/PS1 mice

(2010) Saioa Lagadec et al.   NEUROBIOLOGY OF AGING

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes

(2009) Shin-ichiro Imai   Frontiers in Bioscience-Landmark

Characterizing the Appearance and Growth of Amyloid Plaques in APP/PS1 Mice

(2009) P. Yan et al.   JOURNAL OF NEUROSCIENCE

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition