Biomarkers of Nutrition for Development—Folate Review

Circulating folic acid in plasma: relation to folic acid fortification

(2018) Renee D Kalmbach et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The use of Blood Concentrations of Vitamins and their Respective Functional Indicators to Define Folate and Vitamin B12 Status

(2015) Jacob Selhub et al.   FOOD AND NUTRITION BULLETIN

Review of the Magnitude of Folate and Vitamin B12 Deficiencies Worldwide

(2015) Erin McLean et al.   FOOD AND NUTRITION BULLETIN

Conclusions of a WHO Technical Consultation on Folate and Vitamin B12 Deficiencies

(2015) Bruno de Benoist   FOOD AND NUTRITION BULLETIN

A High Prevalence of Biochemical Evidence of Vitamin B12 or Folate Deficiency does not Translate into a Comparable Prevalence of Anemia

(2015) Jack Metz   FOOD AND NUTRITION BULLETIN

Fortification of Flour with Folic Acid

(2015) Robert J. Berry et al.   FOOD AND NUTRITION BULLETIN

Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals

(2014) Robert Clarke et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Targeted metabolomics and mathematical modeling demonstrate that vitamin B-6 restriction alters one-carbon metabolism in cultured HepG2 cells

(2014) Vanessa R. da Silva et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Population red blood cell folate concentrations for prevention of neural tube defects: bayesian model

(2014) K. S. Crider et al.   BMJ-British Medical Journal

A high-throughput LC-MS/MS method suitable for population biomonitoring measures five serum folate vitamers and one oxidation product

(2013) Zia Fazili et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Blood Pressure in Treated Hypertensive Individuals With the MTHFR 677TT Genotype Is Responsive to Intervention With Riboflavin

(2013) Carol P. Wilson et al.   HYPERTENSION

Genetic Variation: Impact on Folate (and Choline) Bioefficacy

(2013) Allyson A. West et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

B-Vitamins, Methylenetetrahydrofolate Reductase (MTHFR) and Hypertension

(2013) Mary Ward et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Quantification of urinary folate catabolites using liquid chromatography–tandem mass spectrometry

(2013) Mareile Niesser et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Selected Physiologic Variables Are Weakly to Moderately Associated with 29 Biomarkers of Diet and Nutrition, NHANES 2003–2006

(2013) Bridgette M. H. Haynes et al.   JOURNAL OF NUTRITION

Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50 000 individuals

(2013) Stein Emil Vollset et al.   LANCET

Neural tube defects: recent advances, unsolved questions, and controversies

(2013) Andrew J Copp et al.   LANCET NEUROLOGY

Natural killer cell cytotoxicity is not regulated by folic acid in vitro

(2013) Sandra Hirsch et al.   NUTRITION

Folate Catabolites in Spot Urine as Non-Invasive Biomarkers of Folate Status during Habitual Intake and Folic Acid Supplementation

(2013) Mareile Niesser et al.   PLoS One

Characterization and rescue of telomeric abnormalities in ICF syndrome type I fibroblasts

(2013) Shiran Yehezkel et al.   Frontiers in Oncology

Influence of Age, Gender and Lifestyle in Lymphocyte Subsets: Report from the Spanish Gait-2 Study

(2012) María Concepción García-Dabrio et al.   ACTA HAEMATOLOGICA

Folate-status response to a controlled folate intake in nonpregnant, pregnant, and lactating women

(2012) Allyson A West et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

DNA damage in children and adolescents with cardiovascular disease risk factors

(2012) Mariele Kliemann et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Plasticity of DNA methylation in mouse T cell activation and differentiation

(2012) Yan Li et al.   BMC MOLECULAR BIOLOGY

Global Gene Expression Analysis in Cord Blood Reveals Gender-Specific Differences in Response to Carcinogenic Exposure In Utero

(2012) K. Hochstenbach et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Relative Distribution of Folate Species Is Associated with Global DNA Methylation in Human Colorectal Mucosa

(2012) J. Liu et al.   Cancer Prevention Research

Assessing the influence of 5,10-methylenetetrahydrofolate reductase polymorphism on folate stability during long-term frozen storage, thawing, and repeated freeze/thawing of whole blood

(2012) Zia Fazili et al.   CLINICA CHIMICA ACTA

Global DNA hypomethylation in cancer: review of validated methods and clinical significance

(2012) Estela G. Toraño et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Folate deficiency is associated with the formation of complex nuclear anomalies in the cytokinesis-block micronucleus cytome assay

(2012) Caroline F. Bull et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Nutrient intakes and the common mental disorders in women

(2012) Felice N. Jacka et al.   JOURNAL OF AFFECTIVE DISORDERS

Serine Hydroxymethyltransferase Anchorsde NovoThymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis

(2012) Donald D. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polymorphisms in 1-Carbon Metabolism, Epigenetics and Folate-Related Pathologies

(2012) Patrick J. Stover   Journal of Nutrigenetics and Nutrigenomics

Accounting for an Isobaric Interference Allows Correct Determination of Folate Vitamers in Serum by Isotope Dilution-Liquid Chromatography-Tandem MS

(2012) Zia Fazili et al.   JOURNAL OF NUTRITION

Low Colonocyte Folate Is Associated with Uracil Misincorporation and Global DNA Hypomethylation in Human Colorectum

(2012) Angela P. McGlynn et al.   JOURNAL OF NUTRITION

Changes in Measurement Procedure from a Radioassay to a Microbiologic Assay Necessitate Adjustment of Serum and RBC Folate Concentrations in the U.S. Population from the NHANES 1988–2010

(2012) Christine M. Pfeiffer et al.   JOURNAL OF NUTRITION

Estimation of Trends in Serum and RBC Folate in the U.S. Population from Pre- to Postfortification Using Assay-Adjusted Data from the NHANES 1988–2010

(2012) Christine M. Pfeiffer et al.   JOURNAL OF NUTRITION

Do Dietary Supplements Improve Micronutrient Sufficiency in Children and Adolescents?

(2012) Regan L. Bailey et al.   JOURNAL OF PEDIATRICS

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice

(2012) J. Momb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of voluntary fortification and supplement use on dietary intakes of folate and status in an Irish adult population

(2012) S. M. Hopkins et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

(2012) N. Shyh-Chang et al.   SCIENCE

A QC approach to the determination of day-to-day reproducibility and robustness of LC–MS methods for global metabolite profiling in metabonomics/metabolomics

(2012) Helen G Gika et al.   Bioanalysis

The Impact of Nutrition on Differential Methylated Regions of the Genome

(2012) Anne Parle-McDermott et al.   Advances in Nutrition

Trafficking of Intracellular Folates

(2012) Patrick J. Stover et al.   Advances in Nutrition

Folate and DNA Methylation: A Review of Molecular Mechanisms and the Evidence for Folate's Role

(2012) Krista S. Crider et al.   Advances in Nutrition

Examination of Vitamin Intakes among US Adults by Dietary Supplement Use

(2012) Regan Lucas Bailey et al.   Journal of the Academy of Nutrition and Dietetics

Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias

(2012) Robert Clarke et al.   PLOS MEDICINE

Folate status assessment history: implications for measurement of biomarkers in NHANES

(2011) Barry Shane   AMERICAN JOURNAL OF CLINICAL NUTRITION

Dietary folate, but not choline, modifies neural tube defect risk in Shmt1 knockout mice

(2011) Anna E Beaudin et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Biomarkers of folate status in NHANES: a roundtable summary

(2011) Elizabeth A Yetley et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Determination of unmetabolized folic acid in human plasma using affinity HPLC

(2011) Renee Kalmbach et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Folate and vitamin B-12 biomarkers in NHANES: history of their measurement and use

(2011) Elizabeth A Yetley et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Biomarkers of vitamin B-12 status in NHANES: a roundtable summary

(2011) Elizabeth A Yetley et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration

(2011) Simon G. Lamarre et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A Reproducible and High-Throughput HPLC/MS Method To Separate Sarcosine from α- and β-Alanine and To Quantify Sarcosine in Human Serum and Urine

(2011) Tamra E. Meyer et al.   ANALYTICAL CHEMISTRY

LINE-1 Elements in Structural Variation and Disease

(2011) Christine R. Beck et al.   Annual Review of Genomics and Human Genetics

Mechanisms of Membrane Transport of Folates into Cells and Across Epithelia

(2011) Rongbao Zhao et al.   Annual Review of Nutrition

Histone Demethylase LSD1 Is a Folate-Binding Protein

(2011) Zigmund Luka et al.   BIOCHEMISTRY

Hypomethylation of LINE-1 but not Alu in lymphocyte subsets of systemic lupus erythematosus patients

(2011) Jeerawat Nakkuntod et al.   CLINICA CHIMICA ACTA

Isotope Dilution-LC-MS/MS Reference Method Assessment of Serum Folate Assay Accuracy and Proficiency Testing Consensus Mean

(2011) S. Blackmore et al.   CLINICAL CHEMISTRY

Kinetic Modeling of Storage Effects on Biomarkers Related to B Vitamin Status and One-Carbon Metabolism

(2011) S. Hustad et al.   CLINICAL CHEMISTRY

Unintended pregnancy in the United States: incidence and disparities, 2006

(2011) Lawrence B. Finer et al.   CONTRACEPTION

Folic Acid Intake and Spina Bifida in the Era of Dietary Folic Acid Fortification

(2011) Katherine Ahrens et al.   EPIDEMIOLOGY

A genomic point-of-view on environmental factors influencing the human brain methylome

(2011) Janine M. LaSalle   Epigenetics

Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans

(2011) Ayumi Narisawa et al.   HUMAN MOLECULAR GENETICS

Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial

(2011) Celeste A. Jager et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Using the reconstructed genome-scale human metabolic network to study physiology and pathology

(2011) A. Bordbar et al.   JOURNAL OF INTERNAL MEDICINE

Moderate Vitamin B-6 Restriction Does Not Alter Postprandial Methionine Cycle Rates of Remethylation, Transmethylation, and Total Transsulfuration but Increases the Fractional Synthesis Rate of Cystathionine in Healthy Young Men and Women

(2011) Yvonne Lamers et al.   JOURNAL OF NUTRITION

Comparison of Serum and Red Blood Cell Folate Microbiologic Assays for National Population Surveys

(2011) Christine M. Pfeiffer et al.   JOURNAL OF NUTRITION

Folate Intake, Mthfr Genotype, and Sex Modulate Choline Metabolism in Mice

(2011) Tina W. Chew et al.   JOURNAL OF NUTRITION

Whole-genome gene expression modifications associated with nitrosamine exposure and micronucleus frequency in human blood cells

(2011) D. G. A. J. Hebels et al.   MUTAGENESIS

Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity

(2011) Michael Fenech   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

New approaches to modeling complex biochemistry

(2011) John A Bachman et al.   NATURE METHODS

Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria

(2011) D. D. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions

(2011) Krista S. Crider et al.   Nutrients

Genome-Scale Metabolic Modeling Elucidates the Role of Proliferative Adaptation in Causing the Warburg Effect

(2011) Tomer Shlomi et al.   PLoS Computational Biology

Atopy, asthma, and lung function in relation to folate and vitamin B12 in adults

(2010) B. H. Thuesen et al.   ALLERGY

MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline

(2010) Jian Yan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Total folate and folic acid intakes from foods and dietary supplements of US children aged 1–13 y

(2010) Regan L Bailey et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged ≥60 y in the United States

(2010) Regan L Bailey et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Folic acid flour fortification: Impact on the frequencies of 52 congenital anomaly types in three South American countries

(2010) Jorge S. López-Camelo et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Folic Acid Intake Among U.S. Women Aged 15–44 Years, National Health and Nutrition Examination Survey, 2003–2006

(2010) Sarah C. Tinker et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

(2010) Anne S. Tibbetts et al.   Annual Review of Nutrition

Effects of Lowering Homocysteine Levels With B Vitamins on Cardiovascular Disease, Cancer, and Cause-Specific MortalityMeta-analysis of 8 Randomized Trials Involving 37 485 IndividualsEffects of Lowering Homocysteine Levels

(2010)   ARCHIVES OF INTERNAL MEDICINE

The role of metabolites and metabolomics in clinically applicable biomarkers of disease

(2010) Mamas Mamas et al.   ARCHIVES OF TOXICOLOGY

Systematizing the generation of missing metabolic knowledge

(2010) Jeffrey D. Orth et al.   BIOTECHNOLOGY AND BIOENGINEERING

Periconceptional nutrient intakes and risks of neural tube defects in California

(2010) Suzan L. Carmichael et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Folate intake and the risk of colorectal cancer: A systematic review and meta-analysis

(2010) Deborah A. Kennedy et al.   Cancer Epidemiology

Circulating Folate, Vitamin B12, Homocysteine, Vitamin B12 Transport Proteins, and Risk of Prostate Cancer: a Case-Control Study, Systematic Review, and Meta-analysis

(2010) S. M. Collin et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Determination of Total Homocysteine, Methylmalonic Acid, and 2-Methylcitric Acid in Dried Blood Spots by Tandem Mass Spectrometry

(2010) C. T. Turgeon et al.   CLINICAL CHEMISTRY

Systems biology of microbial metabolism

(2010) Matthias Heinemann et al.   CURRENT OPINION IN MICROBIOLOGY

MammalianMTHFD2LEncodes a Mitochondrial Methylenetetrahydrofolate Dehydrogenase Isozyme Expressed in Adult Tissues

(2010) Swetha Bolusani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Navigating the Human Metabolome for Biomarker Identification and Design of Pharmaceutical Molecules

(2010) Irene Kouskoumvekaki et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C→T polymorphism in MTHFR

(2010) Geraldine Horigan et al.   JOURNAL OF HYPERTENSION

Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis

(2010) Susan J. Duthie   JOURNAL OF INHERITED METABOLIC DISEASE

Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects

(2010) Henk J. Blom et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Choline Intake Exceeding Current Dietary Recommendations Preserves Markers of Cellular Methylation in a Genetic Subgroup of Folate-Compromised Men

(2010) William Shin et al.   JOURNAL OF NUTRITION

Analytical Recovery of Folate and Its Degradation Products in Human Serum Stored at −25°C for up to 29 Years

(2010) Rita Hannisdal et al.   JOURNAL OF NUTRITION

Blood Folate Status and Expression of Proteins Involved in Immune Function, Inflammation, and Coagulation: Biochemical and Proteomic Changes in the Plasma of Humans in Response to Long-Term Synthetic Folic Acid Supplementation

(2010) Susan J. Duthie et al.   JOURNAL OF PROTEOME RESEARCH

Association of chromosome damage detected as micronuclei with hematological diseases and micronutrient status

(2010) A. Lal et al.   MUTAGENESIS

Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure

(2010) A. Rossnerova et al.   MUTAGENESIS

The effect of age, gender, diet and lifestyle on DNA damage measured using micronucleus frequency in human peripheral blood lymphocytes

(2010) M. Fenech et al.   MUTAGENESIS

Genetic polymorphisms of genes involved in DNA repair and metabolism influence micronucleus frequencies in human peripheral blood lymphocytes

(2010) V. S. Dhillon et al.   MUTAGENESIS

Automated image analysis of micronuclei by IMSTAR for biomonitoring

(2010) I. Decordier et al.   MUTAGENESIS

THE CONCENTRATION OF “FOLIC ACID”

(2010) Herschel K. Mitchell et al.   NUTRITION REVIEWS

Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial

(2010) A. David Smith et al.   PLoS One

Epigenetic modifications and human pathologies: cancer and CVD

(2010) Susan J. Duthie   PROCEEDINGS OF THE NUTRITION SOCIETY

Interpreting Metabolomic Profiles using Unbiased Pathway Models

(2010) Rahul C. Deo et al.   PLoS Computational Biology

Metabolic Network Topology Reveals Transcriptional Regulatory Signatures of Type 2 Diabetes

(2010) Aleksej Zelezniak et al.   PLoS Computational Biology

Folic acid source, usual intake, and folate and vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003–2006

(2009) Quanhe Yang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Total folate and folic acid intake from foods and dietary supplements in the United States: 2003–2006

(2009) Regan L Bailey et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The logic of the hepatic methionine metabolic cycle

(2009) M.V. Martinov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Insights into metabolic mechanisms underlying folate-responsive neural tube defects: A minireview

(2009) Anna E. Beaudin et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Gene expression profiling in the fetal cardiac tissue after folate and low-dose trichloroethylene exposure

(2009) Patricia T. Caldwell et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Persistent circulating unmetabolised folic acid in a setting of liberal voluntary folic acid fortification. Implications for further mandatory fortification?

(2009) Mary R Sweeney et al.   BMC PUBLIC HEALTH

Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study

(2009) Olivia van Oostrom et al.   Cardiovascular Diabetology

Liquid Chromatography-Tandem Mass Spectrometry Analysis of Folate and Folate Catabolites in Human Serum

(2009) R. Hannisdal et al.   CLINICAL CHEMISTRY

Folate-targeted therapeutic and imaging agents for cancer

(2009) Philip Stewart Low et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Macrophages and Adipocytes in Human Obesity: Adipose Tissue Gene Expression and Insulin Sensitivity During Calorie Restriction and Weight Stabilization

(2009) F. Capel et al.   DIABETES

Choline and Risk of Neural Tube Defects in a Folate-fortified Population

(2009) Gary M. Shaw et al.   EPIDEMIOLOGY

Mitochondrial DNA deletions of blood lymphocytes as genetic markers of low folate-related mitochondrial genotoxicity in peripheral tissues

(2009) Yi-Fang Chou et al.   EUROPEAN JOURNAL OF NUTRITION

Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues

(2009) Rongbao Zhao et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

A common variant inMTHFD1Lis associated with neural tube defects and mRNA splicing efficiency

(2009) Anne Parle-McDermott et al.   HUMAN MUTATION

Mitochondrial C1-Tetrahydrofolate Synthase (MTHFD1L) Supports the Flow of Mitochondrial One-carbon Units into the Methyl Cycle in Embryos

(2009) Schuyler T. Pike et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determination of 5-methyl-2′-deoxycytidine in genomic DNA using high performance liquid chromatography-ultraviolet detection

(2009) Jatinderpal Sandhu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

One-carbon metabolism and breast cancer: an epidemiological perspective

(2009) Xinran Xu et al.   Journal of Genetics and Genomics

One-Carbon Metabolism–Genome Interactions in Folate-Associated Pathologies

(2009) Patrick J. Stover   JOURNAL OF NUTRITION

Analytical Recovery of Folate Degradation Products Formed in Human Serum and Plasma at Room Temperature

(2009) Rita Hannisdal et al.   JOURNAL OF NUTRITION

A Mathematical Model Gives Insights into the Effects of Vitamin B-6 Deficiency on 1-Carbon and Glutathione Metabolism

(2009) H. Frederik Nijhout et al.   JOURNAL OF NUTRITION

Moderate Dietary Vitamin B-6 Restriction Raises Plasma Glycine and Cystathionine Concentrations While Minimally Affecting the Rates of Glycine Turnover and Glycine Cleavage in Healthy Men and Women

(2009) Yvonne Lamers et al.   JOURNAL OF NUTRITION

Predicting metabolic biomarkers of human inborn errors of metabolism

(2009) Tomer Shlomi et al.   Molecular Systems Biology

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

(2009) Arun Sreekumar et al.   NATURE

Folate, cancer risk, and the Greek god, Proteus: a tale of two chameleons

(2009) Joel B Mason   NUTRITION REVIEWS

Folate, Related B Vitamins, and Homocysteine in Childhood and Adolescence: Potential Implications for Disease Risk in Later Life

(2009) M. A. Kerr et al.   PEDIATRICS

The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake

(2009) S. W. Bailey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry

(2009) Øivind Midttun et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Performance Characteristics of Six Homocysteine Assays

(2008) Sonia L. La’ulu et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Neural Tube Defects and Maternal Folate Intake Among Pregnancies Conceived After Folic Acid Fortification in the United States

(2008) B. S. Mosley et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Uracil in DNA: Consequences for carcinogenesis and chemotherapy

(2008) Sondra H. Berger et al.   BIOCHEMICAL PHARMACOLOGY

α Isoforms of soluble and membrane-linked folate-binding protein in human blood

(2008) Mimi Høier-Madsen et al.   BIOSCIENCE REPORTS

Predictive value of folate, vitamin B12 and homocysteine levels in late-life depression

(2008) Jae-Min Kim et al.   BRITISH JOURNAL OF PSYCHIATRY

Commutability of NIST SRM 1955 Homocysteine and Folate in Frozen Human Serum with selected total homocysteine immunoassays and enzymatic assays

(2008) Bryant C. Nelson et al.   CLINICA CHIMICA ACTA

Trends in Circulating Concentrations of Total Homocysteine among US Adolescents and Adults: Findings from the 1991-1994 and 1999-2004 National Health and Nutrition Examination Surveys

(2008) C. M. Pfeiffer et al.   CLINICAL CHEMISTRY

Effects of Delayed Sample Processing and Freezing on Serum Concentrations of Selected Nutritional Indicators

(2008) B. S. Drammeh et al.   CLINICAL CHEMISTRY

Data splitting as a countermeasure against hypothesis fishing: with a case study of predictors for low back pain

(2008) Fredrik A. Dahl et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Contributions of Total Daily Intake of Folic Acid to Serum Folate Concentrations

(2008) Lorraine Yeung   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Time course gene expression in the one-carbon metabolism network using HepG2 cell line grown in folate-deficient medium

(2008) Abalo Chango et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Urinary Water-Soluble Vitamins and Their Metabolite Contents as Nutritional Markers for Evaluating Vitamin Intakes in Young Japanese Women

(2008) Tsutomu FUKUWATARI et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

A highly sensitive single-enzyme homocysteine assay

(2008) Yuying Tan et al.   Nature Protocols

Reduction of the genomic damage level in haemodialysis patients by folic acid and vitamin B12 supplementation

(2008) H. Stopper et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Common Metabolic Profile in Infants Indicating Impaired Cobalamin Status Responds to Cobalamin Supplementation

(2008) A.-L. Bjorke-Monsen et al.   PEDIATRICS

Homocysteine and related B-vitamin status in coeliac disease: Effects of gluten exclusion and histological recovery

(2008) William Dickey et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

A mathematical model of glutathione metabolism

(2008) Michael C Reed et al.   Theoretical Biology and Medical Modelling

An assay for uracil in human DNA at baseline: effect of marginal vitamin B6 deficiency

(2007) Susan T. Mashiyama et al.   ANALYTICAL BIOCHEMISTRY

Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines

(2007) J CROTT et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY