Next-generation interfaces for studying neural function

Conjugated Polymers in Bioelectronics

(2018) Sahika Inal et al.   ACCOUNTS OF CHEMICAL RESEARCH

Optical Probes for Neurobiological Sensing and Imaging

(2018) Eric H. Kim et al.   ACCOUNTS OF CHEMICAL RESEARCH

Electrical Neural Stimulation and Simultaneous in Vivo Monitoring with Transparent Graphene Electrode Arrays Implanted in GCaMP6f Mice

(2018) Dong-Wook Park et al.   ACS Nano

High-Density Stretchable Electrode Grids for Chronic Neural Recording

(2018) Klas Tybrandt et al.   ADVANCED MATERIALS

Superelastic Multimaterial Electronic and Photonic Fibers and Devices via Thermal Drawing

(2018) Yunpeng Qu et al.   ADVANCED MATERIALS

A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice

(2018) Fangmiao Sun et al.   CELL

In Vivo Photopharmacology

(2018) Katharina Hüll et al.   CHEMICAL REVIEWS

Microfabricated Probes for Studying Brain Chemistry: A Review

(2018) Thitaphat Ngernsutivorakul et al.   CHEMPHYSCHEM

Toward true closed-loop neuromodulation: artifact-free recording during stimulation

(2018) Andy Zhou et al.   CURRENT OPINION IN NEUROBIOLOGY

Optogenetic entrainment of neural oscillations with hybrid fiber probes

(2018) Antje Kilias et al.   Journal of Neural Engineering

A genetically encoded fluorescent acetylcholine indicator for in vitro and in vivo studies

(2018) Miao Jing et al.   NATURE BIOTECHNOLOGY

A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters

(2018) Kiryl D. Piatkevich et al.   Nature Chemical Biology

Photoactivatable drugs for nicotinic optopharmacology

(2018) Sambashiva Banala et al.   NATURE METHODS

Wireless optoelectronic photometers for monitoring neuronal dynamics in the deep brain

(2018) Luyao Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A method for single-neuron chronic recording from the retina in awake mice

(2018) Guosong Hong et al.   SCIENCE

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

(2018) Tommaso Patriarchi et al.   SCIENCE

Miniaturized neural system for chronic, local intracerebral drug delivery

(2018) Canan Dagdeviren et al.   Science Translational Medicine

High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics

(2018) Thomas Mager et al.   Nature Communications

Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain

(2018) Ulrike Scheib et al.   Nature Communications

Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays

(2018) Martin Thunemann et al.   Nature Communications

Electrical properties, substrate specificity and optogenetic potential of the engineered light-driven sodium pump eKR2

(2018) Christiane Grimm et al.   Scientific Reports

Silk Fibroin Films Facilitate Single-Step Targeted Expression of Optogenetic Proteins

(2018) Skyler L. Jackman et al.   Cell Reports

Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides

(2018) Olivier Sallin et al.   eLife

Dual color optogenetic control of neural populations using low-noise, multishank optoelectrodes

(2018) Komal Kampasi et al.   Microsystems & Nanoengineering

Rational design of silicon structures for optically controlled multiscale biointerfaces

(2018) Yuanwen Jiang et al.   Nature Biomedical Engineering

A Click Cage: Organelle-Specific Uncaging of Lipid Messengers

(2018) Nicolai Wagner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diode fibres for fabric-based optical communications

(2018) Michael Rein et al.   NATURE

Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS

(2018) William H. Zhang et al.   Nature Chemical Biology

Highly conductive, stretchable and biocompatible Ag–Au core–sheath nanowire composite for wearable and implantable bioelectronics

(2018) Suji Choi et al.   Nature Nanotechnology

In vivo detection of optically-evoked opioid peptide release

(2018) Ream Al-Hasani et al.   eLife

Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR

(2018) Jonathan S. Marvin et al.   NATURE METHODS

High-fidelity multimode fibre-based endoscopy for deep brain in vivo imaging

(2018) Sergey Turtaev et al.   Light-Science & Applications

Sub-millisecond optogenetic control of neuronal firing with two-photon holographic photoactivation of Chronos

(2017) E. Ronzitti et al.   JOURNAL OF NEUROSCIENCE

Nanoelectronic Coating Enabled Versatile Multifunctional Neural Probes

(2017) Zhengtuo Zhao et al.   NANO LETTERS

Fully integrated silicon probes for high-density recording of neural activity

(2017) James J. Jun et al.   NATURE

Virus stamping for targeted single-cell infection in vitro and in vivo

(2017) Rajib Schubert et al.   NATURE BIOTECHNOLOGY

A calcium- and light-gated switch to induce gene expression in activated neurons

(2017) Dongmin Lee et al.   NATURE BIOTECHNOLOGY

A light- and calcium-gated transcription factor for imaging and manipulating activated neurons

(2017) Wenjing Wang et al.   NATURE BIOTECHNOLOGY

Fast high-resolution miniature two-photon microscopy for brain imaging in freely behaving mice

(2017) Weijian Zong et al.   NATURE METHODS

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

(2017) Ken Y Chan et al.   NATURE NEUROSCIENCE

One-step optogenetics with multifunctional flexible polymer fibers

(2017) Seongjun Park et al.   NATURE NEUROSCIENCE

Dynamic illumination of spatially restricted or large brain volumes via a single tapered optical fiber

(2017) Ferruccio Pisanello et al.   NATURE NEUROSCIENCE

Temporally precise single-cell-resolution optogenetics

(2017) Or A. Shemesh et al.   NATURE NEUROSCIENCE

Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex

(2017) William E. Allen et al.   NEURON

Optogenetic Tools for Subcellular Applications in Neuroscience

(2017) Benjamin R. Rost et al.   NEURON

Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors

(2017) Joshua Levitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-term dopamine neurochemical monitoring in primates

(2017) Helen N. Schwerdt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transparent, conformable, active multielectrode array using organic electrochemical transistors

(2017) Wonryung Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deconstructing behavioral neuropharmacology with cellular specificity

(2017) Brenda C. Shields et al.   SCIENCE

The form and function of channelrhodopsin

(2017) Karl Deisseroth et al.   SCIENCE

Semisynthetic fluorescent pH sensors for imaging exocytosis and endocytosis

(2017) Magalie Martineau et al.   Nature Communications

Thermally-drawn fibers with spatially-selective porous domains

(2017) Benjamin Grena et al.   Nature Communications

Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor

(2017) Michael H. Berry et al.   Nature Communications

Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior

(2017) Jonas Wietek et al.   Scientific Reports

Genetically Encoded Photoactuators and Photosensors for Characterization and Manipulation of Pluripotent Stem Cells

(2017) Jordan E. Pomeroy et al.   Theranostics

Neural recording and modulation technologies

(2017) Ritchie Chen et al.   Nature Reviews Materials

Flexible and stretchable nanowire-coated fibers for optoelectronic probing of spinal cord circuits

(2017) Chi Lu et al.   Science Advances

Failure of Standard Training Sets in the Analysis of Fast-Scan Cyclic Voltammetry Data

(2016) Justin A. Johnson et al.   ACS Chemical Neuroscience

Microfabrication and in Vivo Performance of a Microdialysis Probe with Embedded Membrane

(2016) Woong Hee Lee et al.   ANALYTICAL CHEMISTRY

Recent developments of genetically encoded optical sensors for cell biology

(2016) Andrey Bolbat et al.   BIOLOGY OF THE CELL

Targeting Neural Circuits

(2016) Priyamvada Rajasethupathy et al.   CELL

Cell-Type-Specific Optical Recording of Membrane Voltage Dynamics in Freely Moving Mice

(2016) Jesse D. Marshall et al.   CELL

High-Performance Bioinstrumentation for Real-Time Neuroelectrochemical Traumatic Brain Injury Monitoring

(2016) Konstantinos I. Papadimitriou et al.   Frontiers in Human Neuroscience

A Diamond-Based Electrode for Detection of Neurochemicals in the Human Brain

(2016) Kevin E. Bennet et al.   Frontiers in Human Neuroscience

Simultaneous monitoring of potassium, glucose and lactate during spreading depolarization in the injured human brain – Proof of principle of a novel real-time neurochemical analysis system, continuous online microdialysis

(2016) Michelle L Rogers et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Benzoyl chloride derivatization with liquid chromatography–mass spectrometry for targeted metabolomics of neurochemicals in biological samples

(2016) Jenny-Marie T Wong et al.   JOURNAL OF CHROMATOGRAPHY A

Chronicin vivostability assessment of carbon fiber microelectrode arrays

(2016) Paras R Patel et al.   Journal of Neural Engineering

Genetically Targeted All-Optical Electrophysiology with a Transgenic Cre-Dependent Optopatch Mouse

(2016) S. Lou et al.   JOURNAL OF NEUROSCIENCE

Local Control of Extracellular Dopamine Levels in the Medial Nucleus Accumbens by a Glutamatergic Projection from the Infralimbic Cortex

(2016) C. Quiroz et al.   JOURNAL OF NEUROSCIENCE

Isomerically Pure Tetramethylrhodamine Voltage Reporters

(2016) Parker E. Deal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neural probe combining microelectrodes and a droplet-based microdialysis collection system for high temporal resolution sampling

(2016) Guillaume Petit-Pierre et al.   LAB ON A CHIP

Optical inactivation of synaptic AMPA receptors erases fear memory

(2016) Kiwamu Takemoto et al.   NATURE BIOTECHNOLOGY

Optimized second-generation CRY2–CIB dimerizers and photoactivatable Cre recombinase

(2016) Amir Taslimi et al.   Nature Chemical Biology

Stable long-term chronic brain mapping at the single-neuron level

(2016) Tian-Ming Fu et al.   NATURE METHODS

Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain

(2016) Christina K Kim et al.   NATURE METHODS

Genetically encoded indicators of neuronal activity

(2016) Michael Z Lin et al.   NATURE NEUROSCIENCE

Bidirectional modulation of anxiety-related and social behaviors by amygdala projections to the medial prefrontal cortex

(2016) A.C. Felix-Ortiz et al.   NEUROSCIENCE

Beyond the brain: Optogenetic control in the spinal cord and peripheral nervous system

(2016) Kate L. Montgomery et al.   Science Translational Medicine

Structural control of mixed ionic and electronic transport in conducting polymers

(2016) Jonathan Rivnay et al.   Nature Communications

Archaerhodopsin Selectively and Reversibly Silences Synaptic Transmission through Altered pH

(2016) Mohamady El-Gaby et al.   Cell Reports

Sensitive red protein calcium indicators for imaging neural activity

(2016) Hod Dana et al.   eLife

Fiberless multicolor neural optoelectrode for in vivo circuit analysis

(2016) Komal Kampasi et al.   Scientific Reports

Flexible Neural Electrode Array Based-on Porous Graphene for Cortical Microstimulation and Sensing

(2016) Yichen Lu et al.   Scientific Reports

Red-Shifting Azobenzene Photoswitches for in Vivo Use

(2015) Mingxin Dong et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Roadmap to Success in Photopharmacology

(2015) Johannes Broichhagen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Construction of Training Sets for Valid Calibration of in Vivo Cyclic Voltammetric Data by Principal Component Analysis

(2015) Nathan T. Rodeberg et al.   ANALYTICAL CHEMISTRY

BBB leakage, astrogliosis, and tissue loss correlate with silicon microelectrode array recording performance

(2015) Nicholas F. Nolta et al.   BIOMATERIALS

Wireless Optofluidic Systems for Programmable In Vivo Pharmacology and Optogenetics

(2015) Jae-Woong Jeong et al.   CELL

Insertion of linear 8.4μm diameter 16 channel carbon fiber electrode arrays for single unit recordings

(2015) Paras R Patel et al.   Journal of Neural Engineering

Neural probes with multi-drug delivery capability

(2015) Hyogeun Shin et al.   LAB ON A CHIP

Multifunctional fibers for simultaneous optical, electrical and chemical interrogation of neural circuits in vivo

(2015) Andres Canales et al.   NATURE BIOTECHNOLOGY

Transparent intracortical microprobe array for simultaneous spatiotemporal optical stimulation and multichannel electrical recording

(2015) Joonhee Lee et al.   NATURE METHODS

Photoactivatable genetically encoded calcium indicators for targeted neuronal imaging

(2015) Shai Berlin et al.   NATURE METHODS

Optogenetic acidification of synaptic vesicles and lysosomes

(2015) Benjamin R Rost et al.   NATURE NEUROSCIENCE

Mesolimbic dopamine signals the value of work

(2015) Arif A Hamid et al.   NATURE NEUROSCIENCE

Monolithically Integrated μLEDs on Silicon Neural Probes for High-Resolution Optogenetic Studies in Behaving Animals

(2015) Fan Wu et al.   NEURON

A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior

(2015) Eyal Vardy et al.   NEURON

Deep two-photon brain imaging with a red-shifted fluorometric Ca2+indicator

(2015) Carsten Tischbirek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electronic dura mater for long-term multimodal neural interfaces

(2015) I. R. Minev et al.   SCIENCE

Exclusive photorelease of signalling lipids at the plasma membrane

(2015) André Nadler et al.   Nature Communications

Natural Neural Projection Dynamics Underlying Social Behavior

(2014) Lisa A. Gunaydin et al.   CELL

Genetic targeting of chemical indicators in vivo

(2014) Guoying Yang et al.   NATURE METHODS

Noninvasive optical inhibition with a red-shifted microbial rhodopsin

(2014) Amy S Chuong et al.   NATURE NEUROSCIENCE

NeuroGrid: recording action potentials from the surface of the brain

(2014) Dion Khodagholy et al.   NATURE NEUROSCIENCE

Transparent and flexible low noise graphene electrodes for simultaneous electrophysiology and neuroimaging

(2014) Duygu Kuzum et al.   Nature Communications

Enzyme-Modified Carbon-Fiber Microelectrode for the Quantification of Dynamic Fluctuations of Nonelectroactive Analytes Using Fast-Scan Cyclic Voltammetry

(2013) Leyda Z. Lugo-Morales et al.   ANALYTICAL CHEMISTRY

Brain microdialysis and its applications in experimental neurochemistry

(2013) Elmira Anderzhanova et al.   CELL AND TISSUE RESEARCH

Optogenetic stimulation of a hippocampal engram activates fear memory recall

(2012) Xu Liu et al.   NATURE

Genetically Encoded Green Fluorescent Ca2+ Indicators with Improved Detectability for Neuronal Ca2+ Signals

(2012) Masamichi Ohkura et al.   PLoS One

Integrated device for combined optical neuromodulation and electrical recording for chronicin vivoapplications

(2011) Jing Wang et al.   Journal of Neural Engineering

Miniaturized integration of a fluorescence microscope

(2011) Kunal K Ghosh et al.   NATURE METHODS

Toward a comparison of microelectrodes for acute and chronic recordings

(2009) Matthew P. Ward et al.   BRAIN RESEARCH

Chronic microsensors for longitudinal, subsecond dopamine detection in behaving animals

(2009) Jeremy J Clark et al.   NATURE METHODS

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

(2009) Georgia M. Alexander et al.   NEURON

Optical Deconstruction of Parkinsonian Neural Circuitry

(2009) V. Gradinaru et al.   SCIENCE

Improved Temporal Resolution for in Vivo Microdialysis by Using Segmented Flow

(2008) Meng Wang et al.   ANALYTICAL CHEMISTRY

Monitoring Rapid Chemical Communication in the Brain

(2008) Donita L. Robinson et al.   CHEMICAL REVIEWS

High-speed, miniaturized fluorescence microscopy in freely moving mice

(2008) Benjamin A Flusberg et al.   NATURE METHODS

Ceramic-based multisite microelectrode arrays for simultaneous measures of choline and acetylcholine in CNS

(2007) Jason J. Burmeister et al.   BIOSENSORS & BIOELECTRONICS