Optimized second-generation CRY2–CIB dimerizers and photoactivatable Cre recombinase

Actin Flows Mediate a Universal Coupling between Cell Speed and Cell Persistence

(2015) Paolo Maiuri et al.   CELL

Optogenetic Control of Molecular Motors and Organelle Distributions in Cells

(2015) Liting Duan et al.   CHEMISTRY & BIOLOGY

CRISPR-Cas9-based Photoactivatable Transcription System

(2015) Yuta Nihongaki et al.   CHEMISTRY & BIOLOGY

Microsecond Deprotonation of Aspartic Acid and Response of the α/β Subdomain Precede C-Terminal Signaling in the Blue Light Sensor Plant Cryptochrome

(2015) Christian Thöing et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

(2015) Lauren R Polstein et al.   Nature Chemical Biology

Resolving cryptic aspects of cryptochrome signaling: Fig. 1.

(2015) Brian D. Zoltowski   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trp triad-dependent rapid photoreduction is not required for the function ofArabidopsisCRY1

(2015) Jie Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered pairs of distinct photoswitches for optogenetic control of cellular proteins

(2015) Fuun Kawano et al.   Nature Communications

Photo-activatable Cre recombinase regulates gene expression in vivo

(2015) Suzanne E. Schindler et al.   Scientific Reports

Searching for the mechanism of signalling by plant photoreceptor cryptochrome

(2014) Pavel Müller et al.   FEBS LETTERS

Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration

(2014) Patrick R. O'Neill et al.   MOLECULAR BIOLOGY OF THE CELL

Reversible protein inactivation by optogenetic trapping in cells

(2014) Sangkyu Lee et al.   NATURE METHODS

Cellular Metabolites Enhance the Light Sensitivity ofArabidopsisCryptochrome through Alternate Electron Transfer Pathways

(2014) Christopher Engelhard et al.   PLANT CELL

Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins

(2014) Gurkan Guntas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An optimized optogenetic clustering tool for probing protein interaction and function

(2014) Amir Taslimi et al.   Nature Communications

Benchmarking of Optical Dimerizer Systems

(2014) Gopal P. Pathak et al.   ACS Synthetic Biology

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

Live imaging of multicolor-labeled cells in Drosophila

(2013) M. Boulina et al.   DEVELOPMENT

A light-triggered protein secretion system

(2013) Daniel Chen et al.   JOURNAL OF CELL BIOLOGY

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

Optical control of mammalian endogenous transcription and epigenetic states

(2013) Silvana Konermann et al.   NATURE

Optogenetic protein clustering and signaling activation in mammalian cells

(2013) Lukasz J Bugaj et al.   NATURE METHODS

Multi-chromatic control of mammalian gene expression and signaling

(2013) Konrad Müller et al.   NUCLEIC ACIDS RESEARCH

Lifetimes of Arabidopsis cryptochrome signaling statesin vivo

(2013) Vera Herbel et al.   PLANT JOURNAL

Optogenetic Control of PIP3: PIP3 Is Sufficient to Induce the Actin-Based Active Part of Growth Cones and Is Regulated via Endocytosis

(2013) Toshiyuki Kakumoto et al.   PLoS One

Flavin reduction activates Drosophila cryptochrome

(2013) A. T. Vaidya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultraviolet-B-mediated induction of protein–protein interactions in mammalian cells

(2013) Remco P. Crefcoeur et al.   Nature Communications

Multiple bHLH Proteins form Heterodimers to Mediate CRY2-Dependent Regulation of Flowering-Time in Arabidopsis

(2013) Yawen Liu et al.   PLoS Genetics

Decrypting Cryptochrome: Revealing the Molecular Identity of the Photoactivation Reaction

(2012) Ilia A. Solov’yov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light-mediated control of DNA transcription in yeast

(2012) Robert M. Hughes et al.   METHODS

TULIPs: tunable, light-controlled interacting protein tags for cell biology

(2012) Devin Strickland et al.   NATURE METHODS

Optogenetic control of phosphoinositide metabolism

(2012) O. Idevall-Hagren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of full-length Drosophila cryptochrome

(2011) Brian D. Zoltowski et al.   NATURE

Arabidopsis cryptochrome 2 (CRY2) functions by the photoactivation mechanism distinct from the tryptophan (trp) triad-dependent photoreduction

(2011) X. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

Induction of protein-protein interactions in live cells using light

(2009) Masayuki Yazawa et al.   NATURE BIOTECHNOLOGY

Photoexcited CRY2 Interacts with CIB1 to Regulate Transcription and Floral Initiation in Arabidopsis

(2008) H. Liu et al.   SCIENCE