Current state of melanoma diagnosis and treatment

Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline

(2018) Julie R. Brahmer et al.   JOURNAL OF CLINICAL ONCOLOGY

Use of Smartphones for Early Detection of Melanoma: Systematic Review

(2018) Cédric Rat et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Paediatric melanoma

(2017) C. Stefanaki et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Loss of H3K27 trimethylation is not suitable for distinguishing malignant peripheral nerve sheath tumor from melanoma: a study of 387 cases including mimicking lesions

(2017) Sophie Le Guellec et al.   MODERN PATHOLOGY

Marked for death: targeting epigenetic changes in cancer

(2017) Sophia Xiao Pfister et al.   NATURE REVIEWS DRUG DISCOVERY

Immune system and melanoma biology: a balance between immunosurveillance and immune escape

(2017) Anna Passarelli et al.   Oncotarget

Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities

(2017) Goran Micevic et al.   Clinical Epigenetics

Loss of H3K27me3 Expression Is a Highly Sensitive Marker for Sporadic and Radiation-induced MPNST

(2016) Carlos N. Prieto-Granada et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Combinatorial immunotherapy for melanoma

(2016) D D George et al.   CANCER GENE THERAPY

Malignant melanoma—The cradle of anti-neoplastic immunotherapy

(2016) Kristian M. Koller et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Immunostain use in the diagnosis of melanomas referred to a tertiary medical center: a 15-year retrospective review (2001-2015)

(2016) Randie H. Kim et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Loss of H3K27 tri-methylation is a diagnostic marker for malignant peripheral nerve sheath tumors and an indicator for an inferior survival

(2016) Arjen H G Cleven et al.   MODERN PATHOLOGY

Systems Level Analysis of Histone H3 Post-translational Modifications (PTMs) Reveals Features of PTM Crosstalk in Chromatin Regulation

(2016) Veit Schwämmle et al.   MOLECULAR & CELLULAR PROTEOMICS

The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation

(2016) Karine Jacquet et al.   MOLECULAR CELL

Epigenetic therapies by targeting aberrant histone methylome in AML: molecular mechanisms, current preclinical and clinical development

(2016) C T Tsai et al.   ONCOGENE

Tumour-infiltrating lymphocytes in melanoma prognosis and cancer immunotherapy

(2016) Nayoung Lee et al.   PATHOLOGY

Germline MC1R status influences somatic mutation burden in melanoma

(2016) Carla Daniela Robles-Espinoza et al.   Nature Communications

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

A p16-Ki-67-HMB45 immunohistochemistry scoring system as an ancillary diagnostic tool in the diagnosis of melanoma

(2015) Arnaud Uguen et al.   Diagnostic Pathology

The interplay of histone modifications - writers that read

(2015) T. Zhang et al.   EMBO REPORTS

Epigenetic regulation in human melanoma: past and future

(2015) Debina Sarkar et al.   Epigenetics

Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma

(2015) Dirk Schadendorf et al.   JOURNAL OF CLINICAL ONCOLOGY

Melanoma genetics

(2015) Jazlyn Read et al.   JOURNAL OF MEDICAL GENETICS

Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry

(2015) Amanda L. Creech et al.   METHODS

Loss of H3K27 trimethylation distinguishes malignant peripheral nerve sheath tumors from histologic mimics

(2015) Inga-Marie Schaefer et al.   MODERN PATHOLOGY

Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma

(2015) Deepanwita Sengupta et al.   MOLECULAR & CELLULAR PROTEOMICS

Histone H4 Lysine 20 (H4K20) Methylation, Expanding the Signaling Potential of the Proteome One Methyl Moiety at a Time

(2015) Rick van Nuland et al.   MOLECULAR & CELLULAR PROTEOMICS

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure

(2015) S. Premi et al.   SCIENCE

Current Staging and Prognostic Factors in Melanoma

(2015) Edmund K. Bartlett et al.   Surgical Oncology Clinics of North America

The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors

(2015) Daniel Zingg et al.   Nature Communications

Disturbing the histone code in leukemia: translocations and mutations affecting histone methyl transferases

(2015) Martin Chopra et al.   Cancer Genetics

SOX10

(2015) Brian C. Willis et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Histomorphologic Assessment and Interobserver Diagnostic Reproducibility of Atypical Spitzoid Melanocytic Neoplasms With Long-term Follow-up

(2014) Pedram Gerami et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Molecular Pathways: Deregulation of Histone H3 Lysine 27 Methylation in Cancer--Different Paths, Same Destination

(2014) T. Ezponda et al.   CLINICAL CANCER RESEARCH

SET8 methyltransferase activity during the DNA double-strand break response is required for recruitment of 53BP1

(2014) S. Dulev et al.   EMBO REPORTS

5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies

(2014) Jonathan J Lee et al.   MODERN PATHOLOGY

Epigenetics of human melanoma: promises and challenges

(2014) A. Besaratinia et al.   Journal of Molecular Cell Biology

Regulation and Role of EZH2 in Cancer

(2014) Hirohito Yamaguchi et al.   Cancer Research and Treatment

How does pheomelanin synthesis contribute to melanomagenesis?

(2013) Ann M. Morgan et al.   BIOESSAYS

Proteomics in epigenetics: new perspectives for cancer research

(2013) T. Bartke et al.   Briefings in Functional Genomics

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

(2013) Sebastian Bender et al.   CANCER CELL

Historical review of melanoma treatment and outcomes

(2013) Carrie Lee et al.   CLINICS IN DERMATOLOGY

Immunohistochemical expression of p16 in desmoplastic melanoma

(2013) Elena Blokhin et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

TERT Promoter Mutations in Familial and Sporadic Melanoma

(2013) S. Horn et al.   SCIENCE

PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer

(2013) Teruyuki Sato et al.   Scientific Reports

Diagnostic Inaccuracy of Smartphone Applications for Melanoma Detection

(2013) Joel A. Wolf et al.   JAMA Dermatology

CTLA-4 Blockade with Ipilimumab: Long-term Follow-up of 177 Patients with Metastatic Melanoma

(2012) P. A. Prieto et al.   CLINICAL CANCER RESEARCH

Proliferation indices of phosphohistone H3 and Ki67: strong prognostic markers in a consecutive cohort with stage I/II melanoma

(2012) Patricia S Nielsen et al.   MODERN PATHOLOGY

Parallel Reaction Monitoring for High Resolution and High Mass Accuracy Quantitative, Targeted Proteomics

(2012) Amelia C. Peterson et al.   MOLECULAR & CELLULAR PROTEOMICS

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

(2012) Devarati Mitra et al.   NATURE

Driver Mutations in Melanoma: Lessons Learned From Bench-to-Bedside Studies

(2012) Janice M. Mehnert et al.   Current Oncology Reports

Immunohistochemical Double Stains Against Ki67/MART1 and HMB45/MITF: Promising Diagnostic Tools in Melanocytic Lesions

(2011) Patricia Switten Nielsen et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Immunotherapy for melanoma

(2011) Jeffrey Weber   CURRENT OPINION IN ONCOLOGY

Circulating Serologic and Molecular Biomarkers in Malignant Melanoma

(2011) Shanique R. Palmer et al.   MAYO CLINIC PROCEEDINGS

Evolving concepts in melanoma classification and their relevance to multidisciplinary melanoma patient care

(2011) Richard A. Scolyer et al.   Molecular Oncology

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

The Performance of MelaFind

(2010) Gary Monheit et al.   ARCHIVES OF DERMATOLOGY

Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma

(2010) Rita G Ladstein et al.   BMC CANCER

Modulation of T-Cell Activation by Malignant Melanoma Initiating Cells

(2010) T. Schatton et al.   CANCER RESEARCH

Use of immunohistochemistry in the diagnosis of melanocytic lesions: applications and pitfalls

(2010) Doina Ivan et al.   Future Oncology

Melanocortin 1 receptor and risk of cutaneous melanoma: A meta-analysis and estimates of population burden

(2010) Patricia F. Williams et al.   INTERNATIONAL JOURNAL OF CANCER

The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells

(2010) Mathieu Tardat et al.   NATURE CELL BIOLOGY

Staging and Prognosis of Cutaneous Melanoma

(2010) Paxton V. Dickson et al.   Surgical Oncology Clinics of North America

Comparison of pHH3, Ki-67, and Survivin Immunoreactivity in Benign and Malignant Melanocytic Lesions

(2009) Michel R Nasr et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study

(2009) Jedd D Wolchok et al.   LANCET ONCOLOGY

Histone methyltransferases in cancer

(2009) Mareike Albert et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A History of Cancer Chemotherapy

(2008) Vincent T. DeVita et al.   CANCER RESEARCH

Immunohistochemical characteristics of melanoma

(2008) Steven J. Ohsie et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Use of immunohistochemistry in melanocytic lesions

(2008) Victor G. Prieto et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Paul Ehrlich: founder of chemotherapy

(2008) Stefan H. E. Kaufmann   NATURE REVIEWS DRUG DISCOVERY

Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

(2008) Lee E. Finlan et al.   PLoS Genetics