- Home
- Publications
- Publication Search
- Publication Details
Title
Obesity and Breast Cancer: Role of Leptin
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-07-18
DOI
10.3389/fonc.2019.00596
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Obesity, Leptin and Breast Cancer: Epidemiological Evidence and Proposed Mechanisms
- (2019) Sebastiano Andò et al. Cancers
- A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable
- (2019) Alessio Cortellini et al. Journal for ImmunoTherapy of Cancer
- The Surprisingly Positive Association Between Obesity and Cancer Immunotherapy Efficacy
- (2019) William J. Murphy et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The Obesity Paradox in Cancer: How Important Is Muscle?
- (2018) Elizabeth M. Cespedes Feliciano et al. Annual Review of Nutrition
- Leptin-induced ER-α-positive breast cancer cell viability and migration is mediated by suppressing CCN5-signaling via activating JAK/AKT/STAT-pathway
- (2018) Inamul Haque et al. BMC CANCER
- JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance
- (2018) Tianyi Wang et al. Cell Metabolism
- New horizons in breast cancer: the promise of immunotherapy
- (2018) L. de la Cruz-Merino et al. Clinical & Translational Oncology
- BMI and outcomes in melanoma: more evidence for the obesity paradox
- (2018) Andrew J Hayes et al. LANCET ONCOLOGY
- Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis
- (2018) Jennifer L McQuade et al. LANCET ONCOLOGY
- Obesity and breast cancer – Role of estrogens and the molecular underpinnings of aromatase regulation in breast adipose tissue
- (2018) Céline Gérard et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Leptin Signaling Mediates Obesity-Associated CSC Enrichment and EMT in Preclinical TNBC Models
- (2018) Laura W. Bowers et al. MOLECULAR CANCER RESEARCH
- Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
- (2018) Spencer C. Wei et al. Cancer Discovery
- STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance
- (2017) Praveena S Thiagarajan et al. ENDOCRINE-RELATED CANCER
- Leptin induces CREB-dependent aromatase activation through COX-2 expression in breast cancer cells
- (2017) Hyung Gyun Kim et al. FOOD AND CHEMICAL TOXICOLOGY
- Leptin regulation of the p53-HIF1α/PKM2-aromatase axis in breast adipose stromal cells: a novel mechanism for the obesity–breast cancer link
- (2017) H Zahid et al. INTERNATIONAL JOURNAL OF OBESITY
- Combination therapy strategies for improving PD-1 blockade efficacy: a new era in cancer immunotherapy
- (2017) P. S. Chowdhury et al. JOURNAL OF INTERNAL MEDICINE
- Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes
- (2017) Shenying Fang et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Obesity and p16 INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity
- (2017) Huda H. Al-Khalaf et al. MOLECULAR AND CELLULAR BIOLOGY
- Leptin induces ROS via NOX5 in healthy and neoplastic mammary epithelial cells
- (2017) Sinda Mahbouli et al. ONCOLOGY REPORTS
- Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer
- (2017) Ameet K. Mishra et al. PLoS One
- Adipocyte–Tumor Cell Metabolic Crosstalk in Breast Cancer
- (2017) Andrew J. Hoy et al. TRENDS IN MOLECULAR MEDICINE
- Leptin is overexpressed in the tumor microenvironment of obese patients with estrogen receptor positive breast cancer
- (2017) Mohamed Hosney et al. Experimental and Therapeutic Medicine
- Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2
- (2017) Yunxiu Huang et al. CELLULAR ONCOLOGY
- Estrogen receptor signaling mediates leptin-induced growth of breast cancer cells via autophagy induction
- (2017) Pawan Kumar Raut et al. Oncotarget
- Inhibitory effects of BMP9 on breast cancer cells by regulating their interaction with pre-adipocytes/adipocytes
- (2017) Ting Wang et al. Oncotarget
- Immunohistochemical staining of leptin is associated with grade, stage, lymph node involvement, recurrence, and hormone receptor phenotypes in breast cancer
- (2017) Mohamad Nidal Khabaz et al. BMC Womens Health
- Obesity, Inflammation, and Cancer
- (2016) Tuo Deng et al. Annual Review of Pathology-Mechanisms of Disease
- Leptin, obesity and breast cancer: progress to understanding the molecular connections
- (2016) Ines Barone et al. CURRENT OPINION IN PHARMACOLOGY
- Role of inflammation in obesity-related breast cancer
- (2016) Elisa Crespi et al. CURRENT OPINION IN PHARMACOLOGY
- The role of adiponectin in obesity-associated female-specific carcinogenesis
- (2016) Ganji Purnachandra Nagaraju et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Leptin regulates energy metabolism in MCF-7 breast cancer cells
- (2016) Mª del Mar Blanquer-Rosselló et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Leptin promotes breast cancer cell migration and invasion via IL-18 expression and secretion
- (2016) KUANGFA LI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Multifaceted Breast Cancer: The Molecular Connection With Obesity
- (2016) Antonia Feola et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Obesity and Cancer Mechanisms: Tumor Microenvironment and Inflammation
- (2016) Neil M. Iyengar et al. JOURNAL OF CLINICAL ONCOLOGY
- Leptin promotes epithelial-mesenchymal transition of breast cancer via the upregulation of pyruvate kinase M2
- (2016) Lan Wei et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- p53 signaling is involved in leptin-induced growth of hepatic and breast cancer cells
- (2016) Mohan Shrestha et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Obesity and Breast Cancer: Molecular Interconnections and Potential Clinical Applications
- (2016) Valeria Simone et al. ONCOLOGIST
- Sam68 Mediates the Activation of Insulin and Leptin Signalling in Breast Cancer Cells
- (2016) Antonio Pérez-Pérez et al. PLoS One
- APPL1-Mediating Leptin Signaling Contributes to Proliferation and Migration of Cancer Cells
- (2016) Youming Ding et al. PLoS One
- The Obesity Paradox in Cancer: a Review
- (2016) Hannah Lennon et al. Current Oncology Reports
- Activation of IL-8 via PI3K/Akt-dependent pathway is involved in leptin-mediated epithelial-mesenchymal transition in human breast cancer cells
- (2015) Lin Wang et al. CANCER BIOLOGY & THERAPY
- Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
- (2015) Padmanee Sharma et al. CELL
- Chronic-Leptin Attenuates Cisplatin Cytotoxicity in MCF-7 Breast Cancer Cell Line
- (2015) Mercedes Nadal-Serrano et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer
- (2015) N. M. Iyengar et al. CLINICAL CANCER RESEARCH
- Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer
- (2015) Xuyi Wang et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Autophagy induction by leptin contributes to suppression of apoptosis in cancer cells and xenograft model: Involvement of p53/FoxO3A axis
- (2015) Saroj Nepal et al. Oncotarget
- The Interactions of Obesity, Inflammation and Insulin Resistance in Breast Cancer
- (2015) David Rose et al. Cancers
- Integral Role of PTP1B in Adiponectin-Mediated Inhibition of Oncogenic Actions of Leptin in Breast Carcinogenesis
- (2015) LaTonia Taliaferro-Smith et al. NEOPLASIA
- Vitamin D Suppresses Leptin Stimulation of Cancer Growth through microRNA
- (2014) R. Kasiappan et al. CANCER RESEARCH
- 20 YEARS OF LEPTIN: Connecting leptin signaling to biological function
- (2014) Margaret B Allison et al. JOURNAL OF ENDOCRINOLOGY
- Obesity and cancer—mechanisms underlying tumour progression and recurrence
- (2014) Jiyoung Park et al. Nature Reviews Endocrinology
- The obesity paradox: Understanding the effect of obesity on mortality among individuals with cardiovascular disease
- (2014) Hailey R. Banack et al. PREVENTIVE MEDICINE
- Leptin induces CYP1B1 expression in MCF-7 cells through ligand-independent activation of the ERα pathway
- (2014) Tilak Khanal et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Biochemical and molecular mechanisms for the association between obesity, chronic Inflammation, and breast cancer
- (2013) David P. Rose et al. BIOFACTORS
- HER2 induces expression of leptin in human breast epithelial cells
- (2013) Yujin Cha et al. BMB Reports
- Molecular Pathways: Adipose Inflammation as a Mediator of Obesity-Associated Cancer
- (2013) L. R. Howe et al. CLINICAL CANCER RESEARCH
- Role of adipokines and cytokines in obesity-associated breast cancer: Therapeutic targets
- (2013) Sajid Khan et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells
- (2013) Qiao Zheng et al. ENDOCRINE-RELATED CANCER
- Integrating leptin and cAMP signalling pathways in triple-negative breast cancer cells
- (2013) Silvio Naviglio Frontiers in Bioscience-Landmark
- Obesity induced a leptin-Notch signaling axis in breast cancer
- (2013) Monica Battle et al. INTERNATIONAL JOURNAL OF CANCER
- Leptin as a Potential Target for Estrogen Receptor-Positive Breast Cancer
- (2013) Cha Kyong Yom et al. Journal of Breast Cancer
- Leptin–cytokine crosstalk in breast cancer
- (2013) Gale Newman et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Leptin promotes the proliferation and migration of human breast cancer through the extracellular-signal regulated kinase pathway
- (2013) HONG-JUN YUAN et al. Molecular Medicine Reports
- Hyperglycemia Enhances the Proliferation of Non-Tumorigenic and Malignant Mammary Epithelial Cells through Increased leptin/IGF1R Signaling and Activation of AKT/mTOR
- (2013) Rebecca Lopez et al. PLoS One
- Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells
- (2012) Shanchun Guo et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- The balance between leptin and adiponectin in the control of carcinogenesis – Focus on mammary tumorigenesis
- (2012) Michael E. Grossmann et al. BIOCHIMIE
- Leptin attenuates the anti-estrogen effect of tamoxifen in breast cancer
- (2012) Xiaofeng Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- Leptin Mediates Tumor-Stromal Interactions That Promote the Invasive Growth of Breast Cancer Cells
- (2012) I. Barone et al. CANCER RESEARCH
- The cellular and molecular mechanisms by which insulin influences breast cancer risk and progression
- (2012) David P Rose et al. ENDOCRINE-RELATED CANCER
- Leptin-induced Epithelial-Mesenchymal Transition in Breast Cancer Cells Requires β-Catenin Activation via Akt/GSK3- and MTA1/Wnt1 Protein-dependent Pathways
- (2012) Dan Yan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Adipokine leptin in obesity-related pathology of breast cancer
- (2012) Amitabha Ray JOURNAL OF BIOSCIENCES
- Leptin regulates cyclin D1 in luminal epithelial cells of mouse MMTV-Wnt-1 mammary tumors
- (2012) Qiao Zheng et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Leptin increases HER2 protein levels through a STAT3-mediated up-regulation of Hsp90 in breast cancer cells
- (2012) Cinzia Giordano et al. Molecular Oncology
- Increased Levels of COX-2 and Prostaglandin E 2 Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women
- (2012) Kotha Subbaramaiah et al. Cancer Discovery
- In Vivo and in Vitro Evidence That PPARγ Ligands Are Antagonists of Leptin Signaling in Breast Cancer
- (2011) Stefania Catalano et al. AMERICAN JOURNAL OF PATHOLOGY
- Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells
- (2011) B. B. Knight et al. ENDOCRINE-RELATED CANCER
- Leptin receptor signaling: pathways to leptin resistance
- (2011) Joris Wauman Frontiers in Bioscience-Landmark
- Leptin and breast cancer: an overview
- (2011) Mehmet Artac et al. MEDICAL ONCOLOGY
- The multifactorial role of leptin in driving the breast cancer microenvironment
- (2011) Sebastiano Andò et al. Nature Reviews Endocrinology
- Notch, IL-1 and Leptin Crosstalk Outcome (NILCO) Is Critical for Leptin-Induced Proliferation, Migration and VEGF/VEGFR-2 Expression in Breast Cancer
- (2011) Shanchun Guo et al. PLoS One
- Leptin upregulates tissue factor expression in human breast cancer MCF-7 cells
- (2011) Emanuela Napoleone et al. THROMBOSIS RESEARCH
- Leptin upregulates telomerase activity and transcription of human telomerase reverse transcriptase in MCF-7 breast cancer cells
- (2010) He Ren et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells
- (2010) Silvio Naviglio et al. CANCER BIOLOGY & THERAPY
- Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFκB/HIF-1α activation
- (2010) Ruben R. Gonzalez-Perez et al. CELLULAR SIGNALLING
- Cellular and molecular crosstalk between leptin receptor and estrogen receptor-α in breast cancer: molecular basis for a novel therapeutic setting
- (2010) Roberta Fusco et al. ENDOCRINE-RELATED CANCER
- Molecular mechanisms of leptin and adiponectin in breast cancer
- (2010) Thierry Jardé et al. EUROPEAN JOURNAL OF CANCER
- Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies
- (2010) LANCET ONCOLOGY
- Circulating levels of leptin, adiposity and breast cancer risk
- (2009) M-H Wu et al. BRITISH JOURNAL OF CANCER
- Subcellular Localization of Cyclic AMP-Responsive Element Binding Protein-Regulated Transcription Coactivator 2 Provides a Link between Obesity and Breast Cancer in Postmenopausal Women
- (2009) Kristy A. Brown et al. CANCER RESEARCH
- Expression of estrogen receptor alpha increases leptin-induced STAT3 activity in breast cancer cells
- (2009) Nadine A. Binai et al. INTERNATIONAL JOURNAL OF CANCER
- Leptin and Leptin Receptor Expression in Breast Cancer
- (2009) Hee Sung Kim Cancer Research and Treatment
- Leptin/HER2 crosstalk in breast cancer: in vitro study and preliminary in vivoanalysis
- (2008) Elena Fiorio et al. BMC CANCER
- Bidirectional Crosstalk between Leptin and Insulin-like Growth Factor-I Signaling Promotes Invasion and Migration of Breast Cancer Cells via Transactivation of Epidermal Growth Factor Receptor
- (2008) N. K. Saxena et al. CANCER RESEARCH
- Insulin-Dependent Leptin Expression in Breast Cancer Cells
- (2008) V. Bartella et al. CANCER RESEARCH
- Leptin signaling in breast cancer: An overview
- (2008) Donatella Cirillo et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Leptin-regulated gene expression in MCF-7 breast cancer cells: mechanistic insights into leptin-regulated mammary tumor growth and progression
- (2008) Candida N Perera et al. JOURNAL OF ENDOCRINOLOGY
- Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
- (2008) Andrew G Renehan et al. LANCET
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started