Leptin-induced Epithelial-Mesenchymal Transition in Breast Cancer Cells Requires β-Catenin Activation via Akt/GSK3- and MTA1/Wnt1 Protein-dependent Pathways

Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

(2011) Junlin Li et al.   BMC CANCER

Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells

(2011) B. B. Knight et al.   ENDOCRINE-RELATED CANCER

Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival

(2011) Q. Zheng et al.   ENDOCRINE-RELATED CANCER

Targeted Inhibition of  -Catenin/CBP Signaling Ameliorates Renal Interstitial Fibrosis

(2011) S. Hao et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Notch, IL-1 and Leptin Crosstalk Outcome (NILCO) Is Critical for Leptin-Induced Proliferation, Migration and VEGF/VEGFR-2 Expression in Breast Cancer

(2011) Shanchun Guo et al.   PLoS One

Leptin Receptor Signaling Supports Cancer Cell Metabolism through Suppression of Mitochondrial Respiration in Vivo

(2010) Jiyoung Park et al.   AMERICAN JOURNAL OF PATHOLOGY

Obesity and breast cancer: status of leptin and adiponectin in pathological processes

(2010) Michael E. Grossmann et al.   CANCER AND METASTASIS REVIEWS

Metastasis-Associated Protein 1 and Its Short Form Variant Stimulates Wnt1 Transcription through Promoting Its Derepression from Six3 Corepressor

(2010) R. Kumar et al.   CANCER RESEARCH

Metastasis-Associated Protein 1 Short Form Stimulates Wnt1 Pathway in Mammary Epithelial and Cancer Cells

(2010) R. Kumar et al.   CANCER RESEARCH

Cellular and molecular crosstalk between leptin receptor and estrogen receptor-α in breast cancer: molecular basis for a novel therapeutic setting

(2010) Roberta Fusco et al.   ENDOCRINE-RELATED CANCER

Leptin as a potential therapeutic target for breast cancer prevention and treatment

(2010) Amitbha Ray et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Adiponectin antagonizes the oncogenic actions of leptin in hepatocellular carcinogenesis

(2010) Dipali Sharma et al.   HEPATOLOGY

Epithelial-Mesenchymal Transition (EMT) in Tumor-Initiating Cells and Its Clinical Implications in Breast Cancer

(2010) Chad J. Creighton et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression

(2010) Douglas S. Micalizzi et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

The Wnt/β-catenin pathway regulates growth and maintenance of colonospheres

(2010) Shailender S Kanwar et al.   Molecular Cancer

Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

(2010) W. R. Henderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune-Induced Epithelial to Mesenchymal Transition In vivo Generates Breast Cancer Stem Cells

(2009) M. Santisteban et al.   CANCER RESEARCH

Leptin utilizes Jun N-terminal kinases to stimulate the invasion of MCF-7 breast cancer cells

(2009) Vanity McMurtry et al.   CLINICAL & EXPERIMENTAL METASTASIS

LKB1 is required for adiponectin-mediated modulation of AMPK–S6K axis and inhibition of migration and invasion of breast cancer cells

(2009) L Taliaferro-Smith et al.   ONCOGENE

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bidirectional Crosstalk between Leptin and Insulin-like Growth Factor-I Signaling Promotes Invasion and Migration of Breast Cancer Cells via Transactivation of Epidermal Growth Factor Receptor

(2008) N. K. Saxena et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Leptin signaling in breast cancer: An overview

(2008) Donatella Cirillo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Obesity Accelerates Mouse Mammary Tumor Growth in the Absence of Ovarian Hormones

(2008) Nomelí P. Núñez et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

(2008) Anne-Pierre Morel et al.   PLoS One