Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer
Authors
Keywords
Leptin, Breast cancer, Obesity, Cancer treatment, TGF-beta signaling cascade, SMAD signaling, Cancer stem cells, STAT signaling
Journal
PLoS One
Volume 12, Issue 5, Pages e0178454
Publisher
Public Library of Science (PLoS)
Online
2017-05-26
DOI
10.1371/journal.pone.0178454
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A novel leptin antagonist peptide inhibits breast cancer growthin vitroandin vivo
- (2015) Stefania Catalano et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Acute leptin exposure reduces megalin expression and upregulates TGFβ1 in cultured renal proximal tubule cells
- (2015) Jessica F. Briffa et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Breast cancer stem cells, EMT and therapeutic targets
- (2014) Srishti Kotiyal et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Presurgical Trial of Metformin in Overweight and Obese Patients with Newly Diagnosed Breast Cancer
- (2014) Kevin Kalinsky et al. CANCER INVESTIGATION
- Leptin and its receptors
- (2014) Nobuhiro Wada et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Leptin Promotes Metastasis by Inducing an Epithelial-Mesenchymal Transition in A549 Lung Cancer Cells
- (2014) Helin Feng et al. ONCOLOGY RESEARCH
- Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling
- (2014) Y Feng et al. Cell Death & Disease
- Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells
- (2013) Qiao Zheng et al. ENDOCRINE-RELATED CANCER
- The Association between Leptin Level and Breast Cancer: A Meta-Analysis
- (2013) Jingping Niu et al. PLoS One
- The Impact of Obesity on Breast Cancer: A Retrospective Review
- (2012) Danielle J. Haakinson et al. ANNALS OF SURGICAL ONCOLOGY
- Body mass index and survival after breast cancer diagnosis in Japanese women
- (2012) Masaaki Kawai et al. BMC CANCER
- Postmenopausal breast cancer in Iran; risk factors and their population attributable fractions
- (2012) Reza Ghiasvand et al. BMC CANCER
- Leptin Mediates Tumor-Stromal Interactions That Promote the Invasive Growth of Breast Cancer Cells
- (2012) I. Barone et al. CANCER RESEARCH
- Molecular Pathways: Targeting the TGF- Pathway for Cancer Therapy
- (2012) A. L. Smith et al. CLINICAL CANCER RESEARCH
- Body mass index (BMI) and breast cancer: impact on tumor histopatologic features, cancer subtypes and recurrence rate in pre and postmenopausal women
- (2012) Nicoletta Biglia et al. GYNECOLOGICAL ENDOCRINOLOGY
- Complexities of TGF-β Targeted Cancer Therapy
- (2012) Erin C. Connolly et al. International Journal of Biological Sciences
- Interactions Between β-Catenin and Transforming Growth Factor-β Signaling Pathways Mediate Epithelial-Mesenchymal Transition and Are Dependent on the Transcriptional Co-activator cAMP-response Element-binding Protein (CREB)-binding Protein (CBP)
- (2012) Beiyun Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Leptin-induced Epithelial-Mesenchymal Transition in Breast Cancer Cells Requires β-Catenin Activation via Akt/GSK3- and MTA1/Wnt1 Protein-dependent Pathways
- (2012) Dan Yan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion
- (2011) B. Dirat et al. CANCER RESEARCH
- Leptin and cancer: from cancer stem cells to metastasis
- (2011) J. Park et al. ENDOCRINE-RELATED CANCER
- Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival
- (2011) Q. Zheng et al. ENDOCRINE-RELATED CANCER
- Efficacy of a leptin receptor antagonist peptide in a mouse model of triple-negative breast cancer
- (2011) Laszlo Otvos et al. EUROPEAN JOURNAL OF CANCER
- Obesity and breast cancer: status of leptin and adiponectin in pathological processes
- (2010) Michael E. Grossmann et al. CANCER AND METASTASIS REVIEWS
- Metformin attenuates cardiac fibrosis by inhibiting the TGFβ1–Smad3 signalling pathway
- (2010) Han Xiao et al. CARDIOVASCULAR RESEARCH
- Metformin against TGFβ-induced epithelial-to-mesenchymal transition (EMT): From cancer stem cells to aging-associated fibrosis
- (2010) Sílvia Cufí et al. CELL CYCLE
- Circulating levels of leptin, adiposity and breast cancer risk
- (2009) M-H Wu et al. BRITISH JOURNAL OF CANCER
- Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer
- (2009) E. Charafe-Jauffret et al. CLINICAL CANCER RESEARCH
- Expression of estrogen receptor alpha increases leptin-induced STAT3 activity in breast cancer cells
- (2009) Nadine A. Binai et al. INTERNATIONAL JOURNAL OF CANCER
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
- (2008) Anne-Pierre Morel et al. PLoS One
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More