Obesity induced a leptin-Notch signaling axis in breast cancer

Abstract 5282: Leptin induces Notch in endothelial cells: Role of VEGFR-2 transactivation

(2012) Viola Lanier et al.   CANCER RESEARCH

Sixteen years and counting: an update on leptin in energy balance

(2011) Laurent Gautron et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner

(2011) Utpal B Pajvani et al.   NATURE MEDICINE

The cancer stem cell: premises, promises and challenges

(2011) Hans Clevers   NATURE MEDICINE

The multifactorial role of leptin in driving the breast cancer microenvironment

(2011) Sebastiano Andò et al.   Nature Reviews Endocrinology

Notch, IL-1 and Leptin Crosstalk Outcome (NILCO) Is Critical for Leptin-Induced Proliferation, Migration and VEGF/VEGFR-2 Expression in Breast Cancer

(2011) Shanchun Guo et al.   PLoS One

Vascular Endothelial Growth Factor Receptor-2 Couples Cyclo-Oxygenase-2 with Pro-Angiogenic Actions of Leptin on Human Endothelial Cells

(2011) Elena Garonna et al.   PLoS One

Role of obesity-associated dysfunctional adipose tissue in cancer: A molecular nutrition approach

(2010) Pedro L. Prieto-Hontoria et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Effect of obesity on survival of women with breast cancer: systematic review and meta-analysis

(2010) Melinda Protani et al.   BREAST CANCER RESEARCH AND TREATMENT

Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells

(2010) Monica Bartucci et al.   ENDOCRINE-RELATED CANCER

Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway

(2010) S Eliasz et al.   ONCOGENE

Adipose tissue-derived progenitor cells and cancer

(2010) Yan Zhang   World Journal of Stem Cells

Body Mass Index Before and After Breast Cancer Diagnosis: Associations with All-Cause, Breast Cancer, and Cardiovascular Disease Mortality

(2009) H. B. Nichols et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

HER-2, Notch, and Breast Cancer Stem Cells: Targeting an Axis of Evil

(2009) H. Korkaya et al.   CLINICAL CANCER RESEARCH