Nrf2 Induction Re-establishes a Proper Neuronal Differentiation Program in Friedreich’s Ataxia Neural Stem Cells

Ferroptosis as a novel therapeutic target for Friedreich's ataxia

(2019) M. Grazia Cotticelli et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Redox Signaling Mechanisms in Nervous System Development

(2018) Mauricio Olguín-Albuerne et al.   ANTIOXIDANTS & REDOX SIGNALING

A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells

(2018) S. Ray et al.   CELL TRANSPLANTATION

Epigenetic modification of Nrf2 by sulforaphane increases the antioxidative and anti-inflammatory capacity in a cellular model of Alzheimer's disease

(2018) Fangfang Zhao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The role of Nrf2 signaling in counteracting neurodegenerative diseases

(2018) Albena T. Dinkova-Kostova et al.   FEBS Journal

Comparison of Adaptive Neuroprotective Mechanisms of Sulforaphane and its Interconversion Product Erucin in in Vitro and in Vivo Models of Parkinson’s Disease

(2018) Fabiana Morroni et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Sulforaphane Inhibits the Generation of Amyloid-β Oligomer and Promotes Spatial Learning and Memory in Alzheimer’s Disease (PS1V97L) Transgenic Mice

(2018) Ting-Ting Hou et al.   JOURNAL OF ALZHEIMERS DISEASE

Cerebral abnormalities in Friedreich ataxia: A review

(2018) Louisa P. Selvadurai et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Novel Nrf2-Inducer Prevents Mitochondrial Defects and Oxidative Stress in Friedreich’s Ataxia Models

(2018) Rosella Abeti et al.   Frontiers in Cellular Neuroscience

Crucifers and related vegetables and supplements for neurologic disorders

(2018) Anita A. Panjwani et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The role of oxidative stress in Friedreich's ataxia

(2017) Federica Lupoli et al.   FEBS LETTERS

Post-transcriptional regulation of FUS and EWS protein expression by miR-141 during neural differentiation

(2017) Francesca Svetoni et al.   HUMAN MOLECULAR GENETICS

Nrf2-Inducers Counteract Neurodegeneration in Frataxin-Silenced Motor Neurons: Disclosing New Therapeutic Targets for Friedreich’s Ataxia

(2017) Sara Petrillo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer’s Disease

(2017) Qian Cai et al.   JOURNAL OF ALZHEIMERS DISEASE

Friedreich Ataxia: Hypoplasia of Spinal Cord and Dorsal Root Ganglia

(2017) Arnulf H. Koeppen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Prophylactic effects of sulforaphane on depression-like behavior and dendritic changes in mice after inflammation

(2017) Ji-chun Zhang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Nrf2, cellular redox regulation, and neurologic implications

(2017) Eduardo E. Benarroch   NEUROLOGY

Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle-age period

(2016) Mandi J. Corenblum et al.   AGING CELL

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

(2016) Mireille Khacho et al.   Cell Stem Cell

Frataxin silencing alters microtubule stability in motor neurons: implications for Friedreich’s ataxia

(2016) Emanuela Piermarini et al.   HUMAN MOLECULAR GENETICS

Cerebral and cerebellar grey matter atrophy in Friedreich ataxia: the IMAGE-FRDA study

(2016) Louisa P. Selvadurai et al.   JOURNAL OF NEUROLOGY

Optimal ROS Signaling Is Critical for Nuclear Reprogramming

(2016) Gang Zhou et al.   Cell Reports

Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing

(2016) Piergiorgio La Rosa et al.   eLife

Fronto-cerebellar dysfunction and dysconnectivity underlying cognition in friedreich ataxia: The IMAGE-FRDA study

(2015) Ian H. Harding et al.   HUMAN BRAIN MAPPING

Longitudinal magnetic resonance imaging study shows progressive pyramidal and callosal damage in Friedreich's ataxia

(2015) Thiago J.R. Rezende et al.   MOVEMENT DISORDERS

The Cell Biology of Neurogenesis: Toward an Understanding of the Development and Evolution of the Neocortex

(2014) Elena Taverna et al.   Annual Review of Cell and Developmental Biology

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia

(2014) Sunil Sahdeo et al.   HUMAN MOLECULAR GENETICS

Frataxin Silencing Inactivates Mitochondrial Complex I in NSC34 Motoneuronal Cells and Alters Glutathione Homeostasis

(2014) Barbara Carletti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Growth and folding of the mammalian cerebral cortex: from molecules to malformations

(2014) Tao Sun et al.   NATURE REVIEWS NEUROSCIENCE

Nrf2 Regulates Neurogenesis and Protects Neural Progenitor Cells Against Aβ Toxicity

(2014) Virve Kärkkäinen et al.   STEM CELLS

Frataxin Deficiency Leads to Defects in Expression of Antioxidants and Nrf2 Expression in Dorsal Root Ganglia of the Friedreich's Ataxia YG8R Mouse Model

(2013) Yuxi Shan et al.   ANTIOXIDANTS & REDOX SIGNALING

Comparing EPI-743 treatment in siblings with Leber's Hereditary Optic Neuropathy mt14484 mutation

(2013) Carlos F. Chicani et al.   CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE

Cognition in Late-Onset Friedreich Ataxia

(2013) Antonieta Nieto et al.   CEREBELLUM

Frataxin Deficiency Leads to Reduced Expression and Impaired Translocation of NF-E2-Related Factor (Nrf2) in Cultured Motor Neurons

(2013) Valentina D'Oria et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases

(2013) Andrea Tarozzi et al.   Oxidative Medicine and Cellular Longevity

Effect of EPI-743 on the Clinical Course of the Mitochondrial Disease Leber Hereditary Optic Neuropathy

(2012) Alfredo A. Sadun   ARCHIVES OF NEUROLOGY

Decreased functional brain activation in Friedreich ataxia using the Simon effect task

(2012) N. Georgiou-Karistianis et al.   BRAIN AND COGNITION

Iron–sulfur cluster synthesis, iron homeostasis and oxidative stress in Friedreich ataxia

(2012) Rachael A. Vaubel et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

EPI-743 reverses the progression of the pediatric mitochondrial disease—Genetically defined Leigh Syndrome

(2012) Diego Martinelli et al.   MOLECULAR GENETICS AND METABOLISM

Mitochondrial Complex III ROS Regulate Adipocyte Differentiation

(2011) Kathryn V. Tormos et al.   Cell Metabolism

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

(2011) U. P. Shirendeb et al.   HUMAN MOLECULAR GENETICS

Initial experience in the treatment of inherited mitochondrial disease with EPI-743

(2011) Gregory M. Enns et al.   MOLECULAR GENETICS AND METABOLISM

Friedreich Ataxia: Molecular Mechanisms, Redox Considerations, and Therapeutic Opportunities

(2010) Renata Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Dysarthria in Friedreich’s Ataxia: A Perceptual Analysis

(2010) Joanne Folker et al.   FOLIA PHONIATRICA ET LOGOPAEDICA

Nrf2 promotes neuronal cell differentiation

(2009) Fei Zhao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia

(2009) Vincent Paupe et al.   PLoS One

Novel neural stem cell systems

(2008) Luciano Conti et al.   EXPERT OPINION ON BIOLOGICAL THERAPY