Growth and folding of the mammalian cerebral cortex: from molecules to malformations

Mutations in LAMB1 Cause Cobblestone Brain Malformation without Muscular or Ocular Abnormalities

(2013) Farid Radmanesh et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Megalencephaly Syndromes and Activating Mutations in the PI3K-AKT Pathway: MPPH and MCAP

(2013) GHAYDA M. MIRZAA et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Macrocephaly as a Clinical Indicator of Genetic Subtypes in Autism

(2013) Steven Klein et al.   Autism Research

Asymmetric Inheritance of Centrosome-Associated Primary Cilium Membrane Directs Ciliogenesis after Cell Division

(2013) Judith T.M.L. Paridaen et al.   CELL

Trnp1 Regulates Expansion and Folding of the Mammalian Cerebral Cortex by Control of Radial Glial Fate

(2013) Ronny Stahl et al.   CELL

Tuning the cell fate of neurons and glia by microRNAs

(2013) Shan Bian et al.   CURRENT OPINION IN NEUROBIOLOGY

IGF-1 Activates a Cilium-Localized Noncanonical Gβγ Signaling Pathway that Regulates Cell-Cycle Progression

(2013) Celine Yeh et al.   DEVELOPMENTAL CELL

Regulation of cerebral cortex size and folding by expansion of basal progenitors

(2013) Miki Nonaka-Kinoshita et al.   EMBO JOURNAL

Conical expansion of the outer subventricular zone and the role of neocortical folding in evolution and development

(2013) Eric Lewitus et al.   Frontiers in Human Neuroscience

Cortical Gyrification Induced by Fibroblast Growth Factor 2 in the Mouse Brain

(2013) B. G. Rash et al.   JOURNAL OF NEUROSCIENCE

Thalamic Control of Neocortical Area Formation in Mice

(2013) T. Y. Vue et al.   JOURNAL OF NEUROSCIENCE

Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation

(2013) Holden Higginbotham et al.   NATURE NEUROSCIENCE

Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development

(2013) Nathalie Saurat et al.   Neural Development

The Phosphatase PP4c Controls Spindle Orientation to Maintain Proliferative Symmetric Divisions in the Developing Neocortex

(2013) Yunli Xie et al.   NEURON

Cortical Evolution: Judge the Brain by Its Cover

(2013) Daniel H. Geschwind et al.   NEURON

Pax6 Exerts Regional Control of Cortical Progenitor Proliferation via Direct Repression of Cdk6 and Hypophosphorylation of pRb

(2013) Da Mi et al.   NEURON

MicroRNA-92b regulates the development of intermediate cortical progenitors in embryonic mouse brain

(2013) T. J. Nowakowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Geniculocortical Input Drives Genetic Distinctions Between Primary and Higher-Order Visual Areas

(2013) S.-J. Chou et al.   SCIENCE

The Placental Mammal Ancestor and the Post-K-Pg Radiation of Placentals

(2013) M. A. O'Leary et al.   SCIENCE

Development of cortical folding during evolution and ontogeny

(2013) Karl Zilles et al.   TRENDS IN NEUROSCIENCES

The secondary loss of gyrencephaly as an example of evolutionary phenotypical reversal

(2013) Iva Kelava et al.   Frontiers in Neuroanatomy

MicroRNA Cluster miR-17-92 Regulates Neural Stem Cell Expansion and Transition to Intermediate Progenitors in the Developing Mouse Neocortex

(2013) Shan Bian et al.   Cell Reports

Neuropathology of brain and spinal malformations in a case of monosomy 1p36

(2013) Naoko Shiba et al.   Acta Neuropathologica Communications

The cerebral cortex of Albert Einstein: a description and preliminary analysis of unpublished photographs

(2012) Dean Falk et al.   BRAIN

Cobblestone lissencephaly: neuropathological subtypes and correlations with genes of dystroglycanopathies

(2012) Louise Devisme et al.   BRAIN

Malformations of Cortical Development

(2012) Eleonora Aronica et al.   BRAIN PATHOLOGY

Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation

(2012) Yawei J. Yang et al.   CELL

Asymmetric Segregation of the Double-Stranded RNA Binding Protein Staufen2 during Mammalian Neural Stem Cell Divisions Promotes Lineage Progression

(2012) Gretchen Kusek et al.   Cell Stem Cell

PTEN signaling in autism spectrum disorders

(2012) Jing Zhou et al.   CURRENT OPINION IN NEUROBIOLOGY

Spindle orientation in mammalian cerebral cortical development

(2012) Madeline A Lancaster et al.   CURRENT OPINION IN NEUROBIOLOGY

p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex

(2012) G. Mairet-Coello et al.   DEVELOPMENT

Convergent repression of Foxp2 3'UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons

(2012) Y. M. Clovis et al.   DEVELOPMENT

Emerging roles of neural stem cells in cerebral cortex development and evolution

(2012) Víctor Borrell et al.   Developmental Neurobiology

miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling

(2012) Kristin Franke et al.   EMBO JOURNAL

Examining the relationship between early axon growth and transcription factor expression in the developing cerebral cortex

(2012) Tom Lickiss et al.   JOURNAL OF ANATOMY

WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression

(2012) M. A. Bogoyevitch et al.   JOURNAL OF CELL SCIENCE

Dystroglycan on Radial Glia End Feet Is Required for Pial Basement Membrane Integrity and Columnar Organization of the Developing Cerebral Cortex

(2012) Timothy D. Myshrall et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Filamin A Regulates Neural Progenitor Proliferation and Cortical Size through Wee1-Dependent Cdk1 Phosphorylation

(2012) G. Lian et al.   JOURNAL OF NEUROSCIENCE

Primary cilia and forebrain development

(2012) Marc August Willaredt et al.   MECHANISMS OF DEVELOPMENT

Basic Biology and Mechanisms of Neural Ciliogenesis and the B9 Family

(2012) David Gate et al.   MOLECULAR NEUROBIOLOGY

De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes

(2012) Jean-Baptiste Rivière et al.   NATURE GENETICS

De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly

(2012) Jeong Ho Lee et al.   NATURE GENETICS

DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis

(2012) Yu-Ting Yang et al.   NATURE NEUROSCIENCE

Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations

(2012) Annapurna Poduri et al.   NEURON

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

How the Cortex Gets Its Folds: An Inside-Out, Connectivity-Driven Model for the Scaling of Mammalian Cortical Folding

(2012) Bruno Mota et al.   Frontiers in Neuroanatomy

Mammalian Neurogenesis Requires Treacle-Plk1 for Precise Control of Spindle Orientation, Mitotic Progression, and Maintenance of Neural Progenitor Cells

(2012) Daisuke Sakai et al.   PLoS Genetics

Development and Evolution of the Human Neocortex

(2011) Jan H. Lui et al.   CELL

The (Not Necessarily) Convoluted Role of Basal Radial Glia in Cortical Neurogenesis

(2011) R. F. Hevner et al.   CEREBRAL CORTEX

Compartmentalization of Cerebral Cortical Germinal Zones in a Lissencephalic Primate and Gyrencephalic Rodent

(2011) F. Garcia-Moreno et al.   CEREBRAL CORTEX

Germinal Zones in the Developing Cerebral Cortex of Ferret: Ontogeny, Cell Cycle Kinetics, and Diversity of Progenitors

(2011) Isabel Reillo et al.   CEREBRAL CORTEX

Stage-Specific Modulation of Cortical Neuronal Development by Mmu-miR-134

(2011) Philip Gaughwin et al.   CEREBRAL CORTEX

Abundant Occurrence of Basal Radial Glia in the Subventricular Zone of Embryonic Neocortex of a Lissencephalic Primate, the Common Marmoset Callithrix jacchus

(2011) Iva Kelava et al.   CEREBRAL CORTEX

We have got you ‘covered’: how the meninges control brain development

(2011) Julie A Siegenthaler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cilia in the nervous system: linking cilia function and neurodevelopmental disorders

(2011) Ji E Lee et al.   CURRENT OPINION IN NEUROLOGY

The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex

(2011) M. Asami et al.   DEVELOPMENT

Interkinetic Nuclear Movement in the Ventricular Zone of the Cortex

(2011) Orly Reiner et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Polymicrogyria Includes Fusion of the Molecular Layer and Decreased Neuronal Populations But Normal Cortical Laminar Organization

(2011) Alexander R. Judkins et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Local Tissue Growth Patterns Underlying Normal Fetal Human Brain Gyrification Quantified In Utero

(2011) V. Rajagopalan et al.   JOURNAL OF NEUROSCIENCE

Wnt Signaling Regulates Neuronal Differentiation of Cortical Intermediate Progenitors

(2011) R. N. Munji et al.   JOURNAL OF NEUROSCIENCE

FGF Signaling Expands Embryonic Cortical Surface Area by Regulating Notch-Dependent Neurogenesis

(2011) B. G. Rash et al.   JOURNAL OF NEUROSCIENCE

Oblique Radial Glial Divisions in the Developing Mouse Neocortex Induce Self-Renewing Progenitors outside the Germinal Zone That Resemble Primate Outer Subventricular Zone Progenitors

(2011) A. Shitamukai et al.   JOURNAL OF NEUROSCIENCE

Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors

(2011) Aiqun Li et al.   NATURE CELL BIOLOGY

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway

(2011) Ralph Gruber et al.   NATURE CELL BIOLOGY

Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans

(2011) Loïc de Pontual et al.   NATURE GENETICS

A new subtype of progenitor cell in the mouse embryonic neocortex

(2011) Xiaoqun Wang et al.   NATURE NEUROSCIENCE

Cilia in the CNS: The Quiet Organelle Claims Center Stage

(2011) Angeliki Louvi et al.   NEURON

The Cerebrospinal Fluid Provides a Proliferative Niche for Neural Progenitor Cells

(2011) Maria K. Lehtinen et al.   NEURON

Mouse Inscuteable Induces Apical-Basal Spindle Orientation to Facilitate Intermediate Progenitor Generation in the Developing Neocortex

(2011) Maria Pia Postiglione et al.   NEURON

Functional Dicer Is Necessary for Appropriate Specification of Radial Glia during Early Development of Mouse Telencephalon

(2011) Tomasz Jan Nowakowski et al.   PLoS One

Cdk5rap2 exposes the centrosomal root of microcephaly syndromes

(2011) Timothy L. Megraw et al.   TRENDS IN CELL BIOLOGY

GPR56-related bilateral frontoparietal polymicrogyria: further evidence for an overlap with the cobblestone complex

(2010) Nadia Bahi-Buisson et al.   BRAIN

Cortical progenitor expansion, self-renewal and neurogenesis—a polarized perspective

(2010) Simone A Fietz et al.   CURRENT OPINION IN NEUROBIOLOGY

Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors

(2010) S. B. Lizarraga et al.   DEVELOPMENT

Fibroblast growth factor signaling in development of the cerebral cortex

(2010) Tomoko Iwata et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

CDK5RAP2 Regulates Centriole Engagement and Cohesion in Mice

(2010) Jose A. Barrera et al.   DEVELOPMENTAL CELL

Par proteins and neuronal polarity

(2010) Ryan Insolera et al.   Developmental Neurobiology

Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons

(2010) A. Sessa et al.   GENES & DEVELOPMENT

LGN regulates mitotic spindle orientation during epithelial morphogenesis

(2010) Zhen Zheng et al.   JOURNAL OF CELL BIOLOGY

RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells

(2010) Y. Kawase-Koga et al.   JOURNAL OF CELL SCIENCE

Gap Junctions/Hemichannels Modulate Interkinetic Nuclear Migration in the Forebrain Precursors

(2010) X. Liu et al.   JOURNAL OF NEUROSCIENCE

Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations

(2010) Kaya Bilgüvar et al.   NATURE

Neurogenic radial glia in the outer subventricular zone of human neocortex

(2010) David V. Hansen et al.   NATURE

Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture

(2010) Timothy W Yu et al.   NATURE GENETICS

WDR62 is associated with the spindle pole and is mutated in human microcephaly

(2010) Adeline K Nicholas et al.   NATURE GENETICS

OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

(2010) Simone A Fietz et al.   NATURE NEUROSCIENCE

Hook3 Interacts with PCM1 to Regulate Pericentriolar Material Assembly and the Timing of Neurogenesis

(2010) Xuecai Ge et al.   NEURON

Neural Progenitor Nuclei IN Motion

(2010) Elena Taverna et al.   NEURON

Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline

(2010) J. N. Pulvers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Centrioles, Centrosomes, and Cilia in Health and Disease

(2009) Erich A. Nigg et al.   CELL

Retinoic Acid from the Meninges Regulates Cortical Neuron Generation

(2009) Julie A. Siegenthaler et al.   CELL

Cdk4/CyclinD1 Overexpression in Neural Stem Cells Shortens G1, Delays Neurogenesis, and Promotes the Generation and Expansion of Basal Progenitors

(2009) Christian Lange et al.   Cell Stem Cell

Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex

(2009) Tom Kowalczyk et al.   CEREBRAL CORTEX

Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors

(2009) J. N. Pulvers et al.   DEVELOPMENT

Different timings of dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system

(2009) Yoko Kawase-Koga et al.   DEVELOPMENTAL DYNAMICS

Cyclin D2 Is Critical for Intermediate Progenitor Cell Proliferation in the Embryonic Cortex

(2009) S. B. Glickstein et al.   JOURNAL OF NEUROSCIENCE

Asymmetric centrosome inheritance maintains neural progenitors in the neocortex

(2009) Xiaoqun Wang et al.   NATURE

Evolution of the neocortex: a perspective from developmental biology

(2009) Pasko Rakic   NATURE REVIEWS NEUROSCIENCE

A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination

(2009) Chunnian Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex

(2009) Rachel E Thomson et al.   Neural Development

SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice

(2009) Xiaochang Zhang et al.   NEURON

Mammalian Par3 Regulates Progenitor Cell Asymmetric Division via Notch Signaling in the Developing Neocortex

(2009) Ronald S. Bultje et al.   NEURON

Fgf10 Regulates Transition Period of Cortical Stem Cell Differentiation to Radial Glia Controlling Generation of Neurons and Basal Progenitors

(2009) Setsuko Sahara et al.   NEURON

Many roads lead to primary autosomal recessive microcephaly

(2009) Angela M. Kaindl et al.   PROGRESS IN NEUROBIOLOGY

Genetic disorders associated with macrocephaly

(2008) Charles A. Williams et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Neuroepithelial Stem Cell Proliferation Requires LIS1 for Precise Spindle Orientation and Symmetric Division

(2008) Jessica Yingling et al.   CELL

MALS-3 regulates polarity and early neurogenesis in the developing cerebral cortex

(2008) K. Srinivasan et al.   DEVELOPMENT

miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex

(2008) D. De Pietri Tonelli et al.   DEVELOPMENT

Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly

(2008) Lei Chen et al.   DEVELOPMENTAL BIOLOGY

Fanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitors

(2008) Karine Sii-Felice et al.   EMBO JOURNAL

MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation

(2008) Jenn-Yah Yu et al.   EXPERIMENTAL CELL RESEARCH

The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone

(2008) S. J. Arnold et al.   GENES & DEVELOPMENT

Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis

(2008) Stephen C. Noctor et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

(2008) T. H. Davis et al.   JOURNAL OF NEUROSCIENCE

Prospective isolation of functionally distinct radial glial subtypes—Lineage and transcriptome analysis

(2008) Luisa Pinto et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cortical thickness measured from MRI in the YAC128 mouse model of Huntington's disease

(2008) Jason P. Lerch et al.   NEUROIMAGE

Tbr2 Directs Conversion of Radial Glia into Basal Precursors and Guides Neuronal Amplification by Indirect Neurogenesis in the Developing Neocortex

(2008) Alessandro Sessa et al.   NEURON