Frataxin silencing alters microtubule stability in motor neurons: implications for Friedreich’s ataxia
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Title
Frataxin silencing alters microtubule stability in motor neurons: implications for Friedreich’s ataxia
Authors
Keywords
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Journal
HUMAN MOLECULAR GENETICS
Volume 25, Issue 19, Pages 4288-4301
Publisher
Oxford University Press (OUP)
Online
2016-08-12
DOI
10.1093/hmg/ddw260
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Note: Only part of the references are listed.- Glutathione redox imbalance in brain disorders
- (2015) Feng Gu et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
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- (2014) Kurt R. Brunden et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Decreased SIRT2 activity leads to altered microtubule dynamics in oxidatively-stressed neuronal cells: Implications for Parkinson's disease
- (2014) Vivek P. Patel et al. EXPERIMENTAL NEUROLOGY
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- (2014) Sarah Bellouze et al. HUMAN MOLECULAR GENETICS
- Frataxin Silencing Inactivates Mitochondrial Complex I in NSC34 Motoneuronal Cells and Alters Glutathione Homeostasis
- (2014) Barbara Carletti et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Frataxin Deficiency Leads to Defects in Expression of Antioxidants and Nrf2 Expression in Dorsal Root Ganglia of the Friedreich's Ataxia YG8R Mouse Model
- (2013) Yuxi Shan et al. ANTIOXIDANTS & REDOX SIGNALING
- Frataxin Deficiency Leads to Reduced Expression and Impaired Translocation of NF-E2-Related Factor (Nrf2) in Cultured Motor Neurons
- (2013) Valentina D'Oria et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2013) Jonathan A. Cooper JOURNAL OF CELL BIOLOGY
- Glutathione metabolism in cobalamin deficiency type C (cblC)
- (2013) Anna Pastore et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Glutathione: A redox signature in monitoring EPI-743 therapy in children with mitochondrial encephalomyopathies
- (2013) Anna Pastore et al. MOLECULAR GENETICS AND METABOLISM
- Analysis of GSH and GSSG after derivatization with N-ethylmaleimide
- (2013) Daniela Giustarini et al. Nature Protocols
- Clinical Neurogenetics
- (2013) Abigail Collins NEUROLOGIC CLINICS
- Microtubule S-glutathionylation as a potential approach for antimitotic agents
- (2012) Wei Chen et al. BMC CANCER
- S-Glutathionylation signaling in cell biology: Progress and prospects
- (2012) Anna Pastore et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Axon degeneration in Parkinson's disease
- (2012) Robert E. Burke et al. EXPERIMENTAL NEUROLOGY
- Therapeutic Developments in Friedreich Ataxia
- (2012) Robert B. Wilson JOURNAL OF CHILD NEUROLOGY
- Iron–sulfur cluster synthesis, iron homeostasis and oxidative stress in Friedreich ataxia
- (2012) Rachael A. Vaubel et al. MOLECULAR AND CELLULAR NEUROSCIENCE
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- (2012) Diego Martinelli et al. MOLECULAR GENETICS AND METABOLISM
- Dysregulation of Glutathione Homeostasis in Neurodegenerative Diseases
- (2012) William M. Johnson et al. Nutrients
- Idebenone in Friedreich ataxia cardiomyopathy—results from a 6-month phase III study (IONIA)
- (2011) Sarah J. Lagedrost et al. AMERICAN HEART JOURNAL
- Mechanisms of Altered Redox Regulation in Neurodegenerative Diseases—Focus on S-Glutathionylation
- (2011) Elizabeth A. Sabens Liedhegner et al. ANTIOXIDANTS & REDOX SIGNALING
- Posttranslational Modification of Cysteine in Redox Signaling and Oxidative Stress: Focus on S-Glutathionylation
- (2011) John J. Mieyal et al. ANTIOXIDANTS & REDOX SIGNALING
- α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging
- (2011) William D. Shrader et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Friedreich's ataxia: the vicious circle hypothesis revisited
- (2011) Aurélien Bayot et al. BMC Medicine
- Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson’s disease model
- (2011) Won-Seok Choi et al. JOURNAL OF CELL BIOLOGY
- Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich's ataxia: data from a 6-month controlled study followed by a 12-month open-label extension study
- (2011) Thomas Meier et al. JOURNAL OF NEUROLOGY
- plusTipTracker: Quantitative image analysis software for the measurement of microtubule dynamics
- (2011) Kathryn T. Applegate et al. JOURNAL OF STRUCTURAL BIOLOGY
- Initial experience in the treatment of inherited mitochondrial disease with EPI-743
- (2011) Gregory M. Enns et al. MOLECULAR GENETICS AND METABOLISM
- Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions
- (2011) Carsten Janke et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Effect of protein glutathionylation on neuronal cytoskeleton: a potential link to neurodegeneration
- (2011) B. Carletti et al. NEUROSCIENCE
- Friedreich Ataxia: Molecular Mechanisms, Redox Considerations, and Therapeutic Opportunities
- (2010) Renata Santos et al. ANTIOXIDANTS & REDOX SIGNALING
- A Phase 3, Double-blind, Placebo-Controlled Trial of Idebenone in Friedreich Ataxia
- (2010) David R. Lynch et al. ARCHIVES OF NEUROLOGY
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- (2010) Tomohiro Kubo et al. CURRENT BIOLOGY
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- (2010) Niels Galjart CURRENT BIOLOGY
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- (2010) S. Schmucker et al. HUMAN MOLECULAR GENETICS
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- (2010) Daniele Cartelli et al. JOURNAL OF NEUROCHEMISTRY
- Defects in Mitochondrial Axonal Transport and Membrane Potential without Increased Reactive Oxygen Species Production in a Drosophila Model of Friedreich Ataxia
- (2010) Y. Shidara et al. JOURNAL OF NEUROSCIENCE
- Tubulin post-translational modifications: encoding functions on the neuronal microtubule cytoskeleton
- (2010) Carsten Janke et al. TRENDS IN NEUROSCIENCES
- Regulation of microtubule dynamic instability
- (2009) Babet van der Vaart et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system
- (2009) James C. Vickers et al. BRAIN RESEARCH BULLETIN
- Mammalian end binding proteins control persistent microtubule growth
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- Recent advances in our understanding of neurodegeneration
- (2009) Kurt A. Jellinger JOURNAL OF NEURAL TRANSMISSION
- Post-translational modifications of tubulin in the nervous system
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- (2009) Alexandra Seguin et al. MITOCHONDRION
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- (2009) Cecilia Conde et al. NATURE REVIEWS NEUROSCIENCE
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- (2009) Vincent Paupe et al. PLoS One
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