Sulforaphane Inhibits the Generation of Amyloid-β Oligomer and Promotes Spatial Learning and Memory in Alzheimer’s Disease (PS1V97L) Transgenic Mice

Sulforaphane Promotes Mitochondrial Protection in SH-SY5Y Cells Exposed to Hydrogen Peroxide by an Nrf2-Dependent Mechanism

(2017) Marcos Roberto de Oliveira et al.   MOLECULAR NEUROBIOLOGY

The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation

(2017) Fatou Amar et al.   Science Signaling

The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation

(2017) Fatou Amar et al.   Science Signaling

Role of Oxidative Stress in the Progression of Alzheimer's Disease

(2017) Rukhsana Sultana et al.   JOURNAL OF ALZHEIMERS DISEASE

Emerging amyloid disease-modifying drugs for Alzheimer’s disease

(2016) Daniela Galimberti et al.   EXPERT OPINION ON EMERGING DRUGS

Acceleration of Amyloidosis by Inflammation in the Amyloid-Beta Marmoset Monkey Model of Alzheimer’s Disease

(2016) Ingrid H. Philippens et al.   JOURNAL OF ALZHEIMERS DISEASE

Sulforaphane exerts its anti-inflammatory effect against amyloid-β peptide via STAT-1 dephosphorylation and activation of Nrf2/HO-1 cascade in human THP-1 macrophages

(2016) Ye Won An et al.   NEUROBIOLOGY OF AGING

Toxicity mechanisms of arsenic that are shared with neurodegenerative diseases and cognitive impairment: Role of oxidative stress and inflammatory responses

(2016) Claudia Escudero-Lourdes   NEUROTOXICOLOGY

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

(2015) Kirsten L. Viola et al.   ACTA NEUROPATHOLOGICA

Neuroprotective Effects of Sulforaphane on Cholinergic Neurons in Mice with Alzheimer’s Disease-Like Lesions

(2014) Rui Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting the β secretase BACE1 for Alzheimer's disease therapy

(2014) Riqiang Yan et al.   LANCET NEUROLOGY

A Lifespan Observation of a Novel Mouse Model: In Vivo Evidence Supports Aβ Oligomer Hypothesis

(2014) Yichi Zhang et al.   PLoS One

Sulforaphane interaction with amyloid beta 1-40 peptide studied by electrospray ionization mass spectrometry

(2014) V. Nagaveni et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

γ-Secretase inhibitors and modulators

(2013) Todd E. Golde et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

(2013) Sylvain E. Lesné et al.   BRAIN

Why Alzheimer trials fail: removing soluble oligomeric beta amyloid is essential, inconsistent, and difficult

(2013) William I. Rosenblum   NEUROBIOLOGY OF AGING

Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases

(2013) Andrea Tarozzi et al.   Oxidative Medicine and Cellular Longevity

The case for soluble Aβ oligomers as a drug target in Alzheimer's disease

(2013) Franz Hefti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System

(2012) Hwan-Ching Tai et al.   AMERICAN JOURNAL OF PATHOLOGY

Soluble A  Promotes Wild-Type Tau Pathology In Vivo

(2012) M. A. Chabrier et al.   JOURNAL OF NEUROSCIENCE

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems

(2012) Sally Hunter et al.   Alzheimers Research & Therapy

Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease

(2011) Victor L. Villemagne et al.   ANNALS OF NEUROLOGY

Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease

(2011) Chia-Hsiung Chen et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease

(2011) Kazuma Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble Aβ oligomer production and toxicity

(2011) Megan E. Larson et al.   JOURNAL OF NEUROCHEMISTRY

Val97Leu mutant presenilin-1 induces tau hyperphosphorylation and spatial memory deficit in mice and the underlying mechanisms

(2011) Yue Wang et al.   JOURNAL OF NEUROCHEMISTRY

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer’s disease-like pathogenesis in APP+PS1 bigenic mice

(2010) Tomomi Kiyota et al.   FASEB JOURNAL

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE