LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration

Cellular and Molecular Mechanisms of MT1-MMP-Dependent Cancer Cell Invasion

(2016) Antonio Castro-Castro et al.   Annual Review of Cell and Developmental Biology

Nuclear Lamins in Cancer

(2016) Jerome Irianto et al.   Cellular and Molecular Bioengineering

Nuclei migrate through constricted spaces using microtubule motors and actin networks inC. eleganshypodermal cells

(2016) Courtney R. Bone et al.   DEVELOPMENT

Fascin Regulates Nuclear Movement and Deformation in Migrating Cells

(2016) Asier Jayo et al.   DEVELOPMENTAL CELL

Causes and consequences of nuclear envelope alterations in tumour progression

(2016) Emily S. Bell et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Mechanosensing via cell-matrix adhesions in 3D microenvironments

(2016) Andrew D. Doyle et al.   EXPERIMENTAL CELL RESEARCH

Activating the nuclear piston mechanism of 3D migration in tumor cells

(2016) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

Nuclear migration events throughout development

(2016) Courtney R. Bone et al.   JOURNAL OF CELL SCIENCE

Nuclear constriction segregates mobile nuclear proteins away from chromatin

(2016) Jerome Irianto et al.   MOLECULAR BIOLOGY OF THE CELL

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

(2016) M. Raab et al.   SCIENCE

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments

(2016) Hawa-Racine Thiam et al.   Nature Communications

Cdk1 Activates Pre-mitotic Nuclear Envelope Dynein Recruitment and Apical Nuclear Migration in Neural Stem Cells

(2015) Alexandre D. Baffet et al.   DEVELOPMENTAL CELL

Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion

(2015) Dustin G. Thomas et al.   JOURNAL OF CELL BIOLOGY

ARF6–JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion

(2015) Valentina Marchesin et al.   JOURNAL OF CELL BIOLOGY

Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network

(2015) Vira V. Artym et al.   JOURNAL OF CELL BIOLOGY

p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer

(2015) C Lodillinsky et al.   ONCOGENE

Mechanical interplay between invadopodia and the nucleus in cultured cancer cells

(2015) Or-Yam Revach et al.   Scientific Reports

Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments

(2014) Patricia M. Davidson et al.   Cellular and Molecular Bioengineering

Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42–Tuba pathway

(2014) Amélie Juin et al.   JOURNAL OF CELL BIOLOGY

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Nesprins: Tissue-Specific Expression of Epsilon and Other Short Isoforms

(2014) Nguyen Thuy Duong et al.   PLoS One

Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix

(2014) R. J. Petrie et al.   SCIENCE

Nuclear Positioning

(2013) Gregg G. Gundersen et al.   CELL

Nuclear Envelope Composition Determines the Ability of Neutrophil-type Cells to Passage through Micron-scale Constrictions

(2013) Amy C. Rowat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

(2013) Pedro Monteiro et al.   JOURNAL OF CELL BIOLOGY

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Nuclear deformation during breast cancer cell transmigration

(2012) Yi Fu et al.   LAB ON A CHIP

The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration

(2012) Shyam B. Khatau et al.   Scientific Reports

Degrading Devices: Invadosomes in Proteolytic Cell Invasion

(2011) Stefan Linder et al.   Annual Review of Cell and Developmental Biology

Nesprin-3: a versatile connector between the nucleus and the cytoskeleton

(2011) Mirjam Ketema et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Cancer Cell-Associated MT1-MMP Promotes Blood Vessel Invasion and Distant Metastasis in Triple-Negative Mammary Tumors

(2011) J. Y. Perentes et al.   CANCER RESEARCH

Mutually Exclusive Cytoplasmic Dynein Regulation by NudE-Lis1 and Dynactin

(2011) Richard J. McKenney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

(2011) Maria L. Lombardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiological type I collagen organization induces the formation of a novel class of linear invadosomes

(2011) Amélie Juin et al.   MOLECULAR BIOLOGY OF THE CELL

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Interactions Between Nuclei and the Cytoskeleton Are Mediated by SUN-KASH Nuclear-Envelope Bridges

(2010) Daniel A. Starr et al.   Annual Review of Cell and Developmental Biology

LIS1 and NudE Induce a Persistent Dynein Force-Producing State

(2010) Richard J. McKenney et al.   CELL

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development

(2010) K. Natalie Randles et al.   DEVELOPMENTAL DYNAMICS

Kinesin-1 and dynein at the nuclear envelope mediate the bidirectional migrations of nuclei

(2010) Heidi N. Fridolfsson et al.   JOURNAL OF CELL BIOLOGY

β1A Integrin Is a Master Regulator of Invadosome Organization and Function

(2010) Olivier Destaing et al.   MOLECULAR BIOLOGY OF THE CELL

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice

(2009) Xiaochang Zhang et al.   NEURON

Mapping proteolytic cancer cell-extracellular matrix interfaces

(2008) Katarina Wolf et al.   CLINICAL & EXPERIMENTAL METASTASIS

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness

(2008) P.J. Stewart-Hutchinson et al.   EXPERIMENTAL CELL RESEARCH

Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells

(2008) Sachin Hebbar et al.   JOURNAL OF CELL BIOLOGY

Breaching the basement membrane: who, when and how?

(2008) R. Grant Rowe et al.   TRENDS IN CELL BIOLOGY