Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments

Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion

(2015) Dustin G. Thomas et al.   JOURNAL OF CELL BIOLOGY

Altering lamina assembly reveals lamina-dependent and -independent functions for A-type lamins

(2015) M. Zwerger et al.   JOURNAL OF CELL SCIENCE

Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy

(2015) Takeshi Shimi et al.   MOLECULAR BIOLOGY OF THE CELL

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

(2014) Kimberly M. Stroka et al.   CELL

Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments

(2014) Patricia M. Davidson et al.   Cellular and Molecular Bioengineering

Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin

(2014) Amnon Buxboim et al.   CURRENT BIOLOGY

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Nuclear Mechanics and Mechanotransduction in Health and Disease

(2013) Philipp Isermann et al.   CURRENT BIOLOGY

Nuclear Envelope Composition Determines the Ability of Neutrophil-type Cells to Passage through Micron-scale Constrictions

(2013) Amy C. Rowat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

At the leading edge of three-dimensional cell migration

(2013) R. J. Petrie et al.   JOURNAL OF CELL SCIENCE

Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

(2013) Melda Tozluoğlu et al.   NATURE CELL BIOLOGY

Mechanisms of leading edge protrusion in interstitial migration

(2013) Kerry Wilson et al.   Nature Communications

Physical confinement alters tumor cell adhesion and migration phenotypes

(2012) Eric M. Balzer et al.   FASEB JOURNAL

Elucidating mechanical transition effects of invading cancer cells with a subnucleus-scaled microfluidic serial dimensional modulation device

(2012) Michael Mak et al.   LAB ON A CHIP

Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton

(2012) Ke Xu et al.   NATURE METHODS

New dimensions in cell migration

(2012) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chemotaxis of Cell Populations through Confined Spaces at Single-Cell Resolution

(2012) ZiQiu Tong et al.   PLoS One

Microfluidics for Mammalian Cell Chemotaxis

(2011) Beum Jun Kim et al.   ANNALS OF BIOMEDICAL ENGINEERING

Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect

(2011) V. L. R. M. Verstraeten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19

(2011) U. Haessler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A low resistance microfluidic system for the creation of stable concentration gradients in a defined 3D microenvironment

(2010) Ovid C. Amadi et al.   BIOMEDICAL MICRODEVICES

Nuclear mechanics during cell migration

(2010) Peter Friedl et al.   CURRENT OPINION IN CELL BIOLOGY

Open access microfluidic device for the study of cell migration during chemotaxis

(2010) Dawit Jowhar et al.   Integrative Biology

An arrayed high-content chemotaxis assay for patient diagnosis

(2010) Erwin Berthier et al.   Integrative Biology

An Improved Chamber for Direct Visualisation of Chemotaxis

(2010) Andrew J. Muinonen-Martin et al.   PLoS One

Thioredoxin-independent Regulation of Metabolism by the α-Arrestin Proteins

(2009) Parth Patwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced expression of lamin A/C correlates with poor histological differentiation and prognosis in primary gastric carcinoma

(2009) Zhengrong Wu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Lamin A: a putative colonic epithelial stem cell biomarker which identifies colorectal tumours with a more aggressive phenotype

(2008) Naomi D. Willis et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Towards an integrated understanding of the structure and mechanics of the cell nucleus

(2008) Amy C. Rowat et al.   BIOESSAYS